Impact of the endoplasmic reticulum stress response in spinal cord after transient ischemia

Brain Research

Volumn 1169, Issue 1, 2007, Pages 24-33

  Yamauchi, Takashi ^a   Sakurai, Masahiro ^b   Abe, Koji ^c   Matsumiya, Goro ^a   Sawa, Yoshiki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SENDAI CITY MEDICAL CENTER   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Endoplasmic reticulum stress; Ischemia Reperfusion; Spinal cord

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; PROTEIN IRE1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BALLOON CATHETER; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTERNEURON; MOTONEURON; NERVE CELL NECROSIS; NONHUMAN; PARAPLEGIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; RABBIT; REPERFUSION; SPINAL CORD ISCHEMIA; STATISTICAL ANALYSIS; STRESS; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; BIOLOGICAL MARKERS; CELL DEATH; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; INTERNEURONS; ISCHEMIC ATTACK, TRANSIENT; MOLECULAR CHAPERONES; MOTOR NEURON DISEASE; MOTOR NEURONS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; RABBITS; REPERFUSION INJURY; SPINAL CORD; SPINAL CORD ISCHEMIA; TRANS-ACTIVATION (GENETICS);

EUKARYOTA; ORYCTOLAGUS CUNICULUS;

EID: 34548513249     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.06.093     Document Type: Article

References (27)

1. Boyce M., Bryant K.F., Jousse C., Long K., Harding H.P., Scheuner D., Kaufman R.J., Ma D., Coen D.M., Ron D., and Yuan J. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 307 (2005) 935-939
2. DeGracia D.J., Kumar R., Owen C.R., Krause G.S., and White B.C. Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death. J. Cereb. Blood Flow Metab. 22 (2002) 127-141
3. Eldadah B.A., and Faden A.I. Caspase pathways, neuronal apoptosis, and CNS injury. J. Neurotrauma (2000) 17811-17829
4. Hayashi T., Saito A., Okuno S., Ferrand-Drake M., Dodd R.L., and Chan P.H. Oxidative injury to the endoplasmic reticulum in mouse brains after transient focal ischemia. Neurobiol. Dis. 15 (2004) 229-239
5. Hossmann K.A. Disturbances of cerebral protein synthesis and ischemic cell death. Prog. Brain Res. 96 (1993) 161-177
6. Latinis K.M., and Koretzky G.A. Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells. Blood 87 (1996) 871-875
7. Liang P., and MacRae T.H. Molecular chaperones and the cytoskeleton. J. Cell Sci. 110 Pt 13 (1997) 1431-1440
8. Luo S., Baumeister P., Yang S., Abcouwer S.F., and Lee A.S. Induction of Grp78/BiP by translational block. J. Biol. Chem. 278 (2003) 37375-37385
9. Mancini M., Machamer C.E., Roy S., Nicholson D.W., Thornberry N.A., Casciola-Rosen L.A., and Rosen A. Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis. J. Cell Biol. 149 (2000) 603-612
10. Matsui Y., Goh K., Shiiya N., Murashita T., Miyama M., Ohba J., Gohda T., Sakuma M., Yasuda K., and Tanabe T. Clinical application of evoked spinal cord potentials elicited by direct stimulation of the cord during temporary occlusion of the thoracic aorta. J. Thorac. Cardiovasc. Surg. 107 (1994) 1519-1527
11. Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., and Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403 (2000) 98-103
12. Paschen W. Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34 (2003) 365-383
13. Safi H.J., Miller III C.C., Huynh T.T., Estrera A.L., Porat E.E., Winnerkvist A.N., Allen B.S., Hassoun H.T., and Moore F.A. Distal aortic perfusion and cerebrospinal fluid drainage for thoracoabdominal and descending thoracic aortic repair: ten years of organ protection. Ann. Surg. 238 (2003) 372-380 (discussion 380-1)
14. Sakurai M., Aoki M., Abe K., Sadahiro M., and Tabayashi K. Selective motor neuron death and heat shock protein induction after spinal cord ischemia in rabbits. J. Thorac. Cardiovasc. Surg. 113 (1997) 159-164
15. Sakurai M., Hayashi T., Abe K., Yaginuma G., Meguro T., Itoyama Y., and Tabayashi K. Induction of glial cell line-derived neurotrophic factor and c-ret porto-oncogene-like immunoreactivity in rabbit spinal cord after transient ischemia. Neurosci. Lett. 276 (1999) 123-126
16. Sakurai M., Nagata T., Abe K., Horinouchi T., Itoyama Y., and Tabayashi K. Survival and death-promoting events after transient spinal cord ischemia in rabbits: induction of Akt and caspase3 in motor neurons. J. Thorac. Cardiovasc. Surg. 125 (2003) 370-377
17. Sakurai M., Takahashi G., Abe K., Horinouchi T., Itoyama Y., and Tabayashi K. Endoplasmic reticulum stress induced in motor neurons by transient spinal cord ischemia in rabbits. J. Thorac. Cardiovasc. Surg. 130 (2005) 640-645
18. Schmidt-Kastner R., Zhang B., Belayev L., Khoutorova L., Amin R., Busto R., and Ginsberg M.D. DNA microarray analysis of cortical gene expression during early recirculation after focal brain ischemia in rat. Brain Res. Mol. Brain Res. 108 (2002) 81-93
19. Sherman M.Y., and Goldberg A.L. Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases. Neuron 29 (2001) 15-32
20. Tirasophon W., Welihinda A.A., and Kaufman R.J. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev. 12 (1998) 1812-1824
21. Tokumine J., Kakinohana O., Cizkova D., Smith D.W., and Marsala M. Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat. J. Neurosci. Res. 74 (2003) 552-561
22. Travers K.J., Patil C.K., Wodicka L., Lockhart D.J., Weissman J.S., and Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101 (2000) 249-258
23. Urano F., Wang X., Bertolotti A., Zhang Y., Chung P., Harding H.P., and Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287 (2000) 664-666
24. Welihinda A.A., Tirasophon W., and Kaufman R.J. The cellular response to protein misfolding in the endoplasmic reticulum. Gene Expr. 7 (1999) 293-300
25. Westwick J.K., Weitzel C., Minden A., Karin M., and Brenner D.A. Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J. Biol. Chem. 269 (1994) 26396-26401
26. Yoneda T., Imaizumi K., Oono K., Yui D., Gomi F., Katayama T., and Tohyama M. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J. Biol. Chem. 276 (2001) 13935-13940
27. Yu Z., Luo H., Fu W., and Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155 (1999) 302-314