Widespread amyloid deposition in transplanted human pancreatic islets

New England Journal of Medicine

Volumn 359, Issue 9, 2008, Pages 977-979

  Westermark, Gunilla T ^a   Westermark, Per ^b   Berne, Christian ^b   Korsgren, Olle ^b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; DACLIZUMAB; RAPAMYCIN; TACROLIMUS;

ANAMNESIS; CLINICAL FEATURE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY GRAFT REJECTION; LETTER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PATHOGENESIS; PRIORITY JOURNAL;

EID: 50449085533     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0802893     Document Type: Letter

References (5)

1. Shapiro AMJ, Lakey JRT, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-8.
2. Shapiro AMJ, Ricordi C, Hering BJ, et al. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006;355:1318-30.
3. Lorenzo A, Razzaboni B, Weir GC, Yankner BA. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature 1994;368:756-60.
4. Westermark P, Eizirik DL, Pipeleers DG, Hellerström C, Andersson A. Rapid deposition of amyloid in human islets transplanted into nude mice. Diabetologia 1995;38:543-9.
5. Westermark GT, Westermark P, Eizirik D, et al. Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice. Metabolism 1999;48:448-54.