Fas and activated caspase 8 in normal, Alzheimer and multiple infarct brains

Neuroscience Letters

Volumn 367, Issue 1, 2004, Pages 113-117

  Yew, David T ^a   Ping Li, Wei ^b   Liu, W K ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Alzheimer; Caspase 8; Fas; Multiple infarcts; Normal aging; Plaque

Indexed keywords

CASPASE 8; CELL ENZYME; FAS ANTIGEN; MEMBRANE RECEPTOR;

AGED; ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; BRAIN INFARCTION; BRAIN NERVE CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; FRONTAL LOBE; GLIA CELL; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; OCCIPITAL LOBE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SENILE PLAQUE;

EID: 4043106345     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.05.091     Document Type: Article

References (18)

1. Busciglio J., Gabuzda D.H., Matsudaira P., Yankner B.A. Generation of beta amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc. Natl. Acad. Sci. U.S.A. 90:1993;2092-2096
2. Chinnaiyan A.M., Dixit V.M. Portrait of an executioner: the molecular mechanism of Fas/APO-1 induced apoptosis. Semin. Immunol. 9:1997;6-76
3. De la Monte S.M., Sohn Y.K., Ganju N., Wards J.R. P53 and CD 95 associated apoptosis in neurodegenerative diseases. Lab. Invest. 78:1998;401-4118
4. De la Monte S.M., Sohn Y.K., Wards J.R. Correlates of P53 and Fas (CD 95)-mediated apoptosis in Alzheimer's disease. J. Neurol. Sci. 6:1997;73-83
5. Eischen C.M., Leibson P.J. The Fas pathway in apoptosis. Adv. Pharmacol. 41:1997;107-132
6. Engidawork E., Gulesserian T., Yoo B.C., Cairns N., Lubec G. Alternation of caspases and apoptosis-related proteins in brains of patients with Alzheimer's disease. Biochem. Biophys. Res. Commun. 281:2001;84-93
7. Estus S., Tucker H.M., Rooyan C., van Wright S., Brigham E.F., Wogulis M., Rybel R.E. Aggregated amyloid-beta protein induces cortical apoptosis and concomitant "apoptotic" pattern of gene induction. J. Neurosci. 17:1997;7736-7746
8. Ferrer I., Puig B., Krupinski J., Carmona M., Blanco R. Fas and Fas ligand expression in Alzheimer's disease. Acta Neuropathol. 102:2001;121-131
9. Forloni G. Neurotoxicity of β amyloid and prion peptides. Curr. Opin. Neurol. 9:1996;492-500
10. Gottlieb R.A., Babior B.M. Regulation of Fas mediated apoptosis. Curr. Top. Cell Regul. 35:1997;69-105
11. Ivins K.J., Thomton P.C., Rohn T.T., Cotman C.W. Neuronal apoptosis induced by β amyloid is medicated by caspase 8. Neurobiol. Dis. 6:1999;440-449
12. Krammer P.H. The CD 95 (APO-1/Fas) CD 95L system. Toxicol. Lett. 102:1998;131-137
13. Li W.P., Chan W.Y., Lai H.W.L., Yew D.T. Terminal dUTP nick end labelling (TUNEL) positive cells in different regions of the brain in normal aging and Alzheimer patients. J. Mol. Neurosci. 8:1997;75-82
14. Nagata S. Apoptosis mediated by the Fas system. Prog. Mol. Subcell. Biol. 16:1996;87-103
15. Nishimura T., Akiyama H., Yonehara S., Kondo H., Ikeda K., Kato M., Iseki E., Kosaka K. Fas antigen expression in brains of patients with Alzheimer-type dementia. Brain Res. 695:1995;137-145
16. Selznick L.A., Holtman D.M., Han B.M., Gökden M., Srinivasan A.N., Johnson E.M., Roth K.A. In situ immunodetection of neuronal caspase 3 activation in Alzheimer disease. J. Neuropathol. Exp. Neurol. 58:1999;1020-1026
17. Selznick L.A., Zheng T.S., Flavell R.A., Rakic P., Roth K.A. Amyloid beta-induced neuronal death is Bax-dependent but caspase independent. J. Neuropathol. Exp. Neurol. 57:2000;714-717
18. Wallach D., Varfolomeer E., Malinin N., Goltser Y., Kovalenko A., Boldin M. Tumor necrosis factor receptor and Fas signaling mechanisms. Ann. Rev. Immunol. 17:1999;331-367