Presenilin-1 regulates the expression of p62 to govern p62-dependent tau degradation

Molecular Neurobiology

Volumn 49, Issue 1, 2014, Pages 10-27

  Tung, Ying Tsen ^a,b   Wang, Bo Jeng ^a,b   Hsu, Wen Ming ^c   Hu, Ming Kuan ^d   Her, Guor Mour ^e   Huang, Wei Pang ^b   Liao, Yung Feng ^a,b  

^a INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^e NATIONAL TAIWAN OCEAN UNIVERSITY   (Taiwan)

Author keywords

Alzheimer's disease; Autophagy; p62; Presenilin; Tau; Secretase

Indexed keywords

GAMMA SECRETASE; MESSENGER RNA; PRESENILIN 1; PROTEIN KINASE B; PROTEIN P62; TAU PROTEIN; TRANSCRIPTION FACTOR AP 1;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; CELL FUNCTION; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; REVIEW;

ANIMALS; CELL LINE, TUMOR; DOWN-REGULATION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; PHENOTYPE; PRESENILIN-1; PROTEOLYSIS; RNA-BINDING PROTEINS; TAU PROTEINS; ZEBRAFISH;

EID: 84894364673     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8482-y     Document Type: Review

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