The binding and phosphorylation of Thr231 is critical for Tau's hyperphosphorylation and functional regulation by glycogen synthase kinase 3β

Journal of Neurochemistry

Volumn 103, Issue 2, 2007, Pages 802-813

  Lin, Yuh Te ^a,b   Cheng, Jiin Tsuey ^a   Liang, Li Ching ^b   Ko, Chiung Yuan ^a   Lo, Yuk Keung ^b   Lu, Pei Jung ^a,b  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Alzheimer's disease; Glycogen synthase kinase 3 ; Hyperphosphorylation; Tau; Thr231

Indexed keywords

ALANYLVALYLVALYLARGINYLTHREONYLPROLYLPROLYLLYSYLSERYLPROLYLSERYLSERINE; AMINO ACID; GLYCOGEN SYNTHASE KINASE 3BETA; MUTANT PROTEIN; TAU PROTEIN; THREONINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME REGULATION; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION;

BINDING SITES; BLOTTING, WESTERN; CELL LINE; CIRCULAR DICHROISM; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOPRECIPITATION; LIGHT; NEUROFIBRILLARY TANGLES; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN CONFORMATION; SCATTERING, RADIATION; TAU PROTEINS; THREONINE; THROMBIN; TRANSFECTION; TUBULIN;

EID: 34848845327     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04792.x     Document Type: Article

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