-
1
-
-
58149337392
-
Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling
-
Akerfeldt M.C., Howes J., Chan J.Y., Stevens V.A., Boubenna N., McGuire H.M., et al. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. Diabetes 2008, 57(11):3034-3044.
-
(2008)
Diabetes
, vol.57
, Issue.11
, pp. 3034-3044
-
-
Akerfeldt, M.C.1
Howes, J.2
Chan, J.Y.3
Stevens, V.A.4
Boubenna, N.5
McGuire, H.M.6
-
2
-
-
0033957476
-
Transgenic overexpression of human Bcl-2 in islet beta cells inhibits apoptosis but does not prevent autoimmune destruction
-
Allison J., Thomas H., Beck D., Brady J.L., Lew A.M., Elefanty A., et al. Transgenic overexpression of human Bcl-2 in islet beta cells inhibits apoptosis but does not prevent autoimmune destruction. International Immunology 2000, 12(1):9-17.
-
(2000)
International Immunology
, vol.12
, Issue.1
, pp. 9-17
-
-
Allison, J.1
Thomas, H.2
Beck, D.3
Brady, J.L.4
Lew, A.M.5
Elefanty, A.6
-
3
-
-
0032146564
-
IL-1 produced and released endogenously within human islets inhibits beta cell function
-
Arnush M., Heitmeier M.R., Scarim A.L., Marino M.H., Manning P.T., Corbett J.A. IL-1 produced and released endogenously within human islets inhibits beta cell function. Journal of Clinical Investigation 1998, 102(3):516-526.
-
(1998)
Journal of Clinical Investigation
, vol.102
, Issue.3
, pp. 516-526
-
-
Arnush, M.1
Heitmeier, M.R.2
Scarim, A.L.3
Marino, M.H.4
Manning, P.T.5
Corbett, J.A.6
-
4
-
-
0032521025
-
Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes
-
Arnush M., Scarim A.L., Heitmeier M.R., Kelly C.B., Corbett J.A. Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes. Journal of Immunology 1998, 160(6):2684-2691.
-
(1998)
Journal of Immunology
, vol.160
, Issue.6
, pp. 2684-2691
-
-
Arnush, M.1
Scarim, A.L.2
Heitmeier, M.R.3
Kelly, C.B.4
Corbett, J.A.5
-
5
-
-
0344837711
-
Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression
-
Barbu A.R., Akusjarvi G., Welsh N. Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression. Molecular Medicine 2002, 8(11):733-741.
-
(2002)
Molecular Medicine
, vol.8
, Issue.11
, pp. 733-741
-
-
Barbu, A.R.1
Akusjarvi, G.2
Welsh, N.3
-
6
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
Bendtzen K., Mandrup-Poulsen T., Nerup J., Nielsen J.H., Dinarello C.A., Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science 1986, 232(4757):1545-1547.
-
(1986)
Science
, vol.232
, Issue.4757
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
7
-
-
0034596017
-
IB1 reduces cytokine-induced apoptosis of insulin-secreting cells
-
Bonny C., Oberson A., Steinmann M., Schorderet D.F., Nicod P., Waeber G. IB1 reduces cytokine-induced apoptosis of insulin-secreting cells. Journal of Biological Chemistry 2000, 275(22):16466-16472.
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.22
, pp. 16466-16472
-
-
Bonny, C.1
Oberson, A.2
Steinmann, M.3
Schorderet, D.F.4
Nicod, P.5
Waeber, G.6
-
8
-
-
19944432792
-
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells
-
Cardozo A.K., Ortis F., Storling J., Feng Y.M., Rasschaert J., Tonnesen M., et al. Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells. Diabetes 2005, 54(2):452-461.
-
(2005)
Diabetes
, vol.54
, Issue.2
, pp. 452-461
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
Feng, Y.M.4
Rasschaert, J.5
Tonnesen, M.6
-
9
-
-
0027934873
-
TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide
-
Cetkovic-Cvrlje M., Eizirik D.L. TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide. Cytokine 1994, 6(4):399-406.
-
(1994)
Cytokine
, vol.6
, Issue.4
, pp. 399-406
-
-
Cetkovic-Cvrlje, M.1
Eizirik, D.L.2
-
10
-
-
38449122843
-
The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death
-
Chambers K.T., Unverferth J.A., Weber S.M., Wek R.C., Urano F., Corbett J.A. The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death. Diabetes 2008, 57(1):124-132.
-
(2008)
Diabetes
, vol.57
, Issue.1
, pp. 124-132
-
-
Chambers, K.T.1
Unverferth, J.A.2
Weber, S.M.3
Wek, R.C.4
Urano, F.5
Corbett, J.A.6
-
11
-
-
78349309166
-
Cyclophilin A release as a biomarker of necrotic cell death
-
Christofferson D.E., Yuan J. Cyclophilin A release as a biomarker of necrotic cell death. Cell Death and Differentiation 2010, 17(12):1942-1943.
-
(2010)
Cell Death and Differentiation
, vol.17
, Issue.12
, pp. 1942-1943
-
-
Christofferson, D.E.1
Yuan, J.2
-
12
-
-
33644749322
-
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
Cnop M., Welsh N., Jonas J.C., Jorns A., Lenzen S., Eizirik D.L. Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities. Diabetes 2005, 54(Suppl. 2):S97-S107.
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jorns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
13
-
-
79960901784
-
Pancreatic beta-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis
-
Collier J.J., Burke S.J., Eisenhauer M.E., Lu D., Sapp R.C., Frydman C.J., et al. Pancreatic beta-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis. PloS One 2011, 6(7):e22485.
-
(2011)
PloS One
, vol.6
, Issue.7
-
-
Collier, J.J.1
Burke, S.J.2
Eisenhauer, M.E.3
Lu, D.4
Sapp, R.C.5
Frydman, C.J.6
-
14
-
-
33745316621
-
Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines
-
Collier J.J., Fueger P.T., Hohmeier H.E., Newgard C.B. Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines. Diabetes 2006, 55(5):1398-1406.
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1398-1406
-
-
Collier, J.J.1
Fueger, P.T.2
Hohmeier, H.E.3
Newgard, C.B.4
-
15
-
-
0023216442
-
Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans
-
Comens P.G., Wolf B.A., Unanue E.R., Lacy P.E., McDaniel M.L. Interleukin 1 is potent modulator of insulin secretion from isolated rat islets of Langerhans. Diabetes 1987, 36(8):963-970.
-
(1987)
Diabetes
, vol.36
, Issue.8
, pp. 963-970
-
-
Comens, P.G.1
Wolf, B.A.2
Unanue, E.R.3
Lacy, P.E.4
McDaniel, M.L.5
-
16
-
-
0025720502
-
Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion
-
Corbett J.A., Lancaster J.R., Sweetland M.A., McDaniel M.L. Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion. Journal of Biological Chemistry 1991, 266(32):21351-21354.
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.32
, pp. 21351-21354
-
-
Corbett, J.A.1
Lancaster, J.R.2
Sweetland, M.A.3
McDaniel, M.L.4
-
17
-
-
0028181046
-
Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase
-
Corbett J.A., McDaniel M.L. Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase. Biochemical Journal 1994, 299(Pt. 3):719-724.
-
(1994)
Biochemical Journal
, vol.299
, Issue.PART. 3
, pp. 719-724
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
18
-
-
0028900805
-
Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
-
Corbett J.A., McDaniel M.L. Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. Journal of Experimental Medicine 1995, 181(2):559-568.
-
(1995)
Journal of Experimental Medicine
, vol.181
, Issue.2
, pp. 559-568
-
-
Corbett, J.A.1
McDaniel, M.L.2
-
19
-
-
0027534895
-
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans
-
Corbett J.A., Sweetland M.A., Wang J.L., Lancaster J.R., McDaniel M.L. Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. Proceedings of the National Academy of Sciences of the United States of America 1993, 90(5):1731-1735.
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.5
, pp. 1731-1735
-
-
Corbett, J.A.1
Sweetland, M.A.2
Wang, J.L.3
Lancaster, J.R.4
McDaniel, M.L.5
-
20
-
-
0026793534
-
Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction
-
Corbett J.A., Wang J.L., Hughes J.H., Wolf B.A., Sweetland M.A., Lancaster J.R., et al. Nitric oxide and cyclic GMP formation induced by interleukin 1 beta in islets of Langerhans. Evidence for an effector role of nitric oxide in islet dysfunction. Biochemical Journal 1992, 287(Pt. 1):229-235.
-
(1992)
Biochemical Journal
, vol.287
, Issue.PART. 1
, pp. 229-235
-
-
Corbett, J.A.1
Wang, J.L.2
Hughes, J.H.3
Wolf, B.A.4
Sweetland, M.A.5
Lancaster, J.R.6
-
21
-
-
0027054055
-
Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide
-
Corbett J.A., Wang J.L., Sweetland M.A., Lancaster J.R., McDaniel M.L. Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide. Journal of Clinical Investigation 1992, 90(6):2384-2391.
-
(1992)
Journal of Clinical Investigation
, vol.90
, Issue.6
, pp. 2384-2391
-
-
Corbett, J.A.1
Wang, J.L.2
Sweetland, M.A.3
Lancaster, J.R.4
McDaniel, M.L.5
-
22
-
-
0027428461
-
Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
-
Delaney C.A., Green M.H., Lowe J.E., Green I.C. Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Letters 1993, 333(3):291-295.
-
(1993)
FEBS Letters
, vol.333
, Issue.3
, pp. 291-295
-
-
Delaney, C.A.1
Green, M.H.2
Lowe, J.E.3
Green, I.C.4
-
23
-
-
0023768414
-
Interleukin-1 induced impairment in pancreatic islet oxidative metabolism of glucose is potentiated by tumor necrosis factor
-
Eizirik D.L. Interleukin-1 induced impairment in pancreatic islet oxidative metabolism of glucose is potentiated by tumor necrosis factor. Acta Endocrinologica 1988, 119(3):321-325.
-
(1988)
Acta Endocrinologica
, vol.119
, Issue.3
, pp. 321-325
-
-
Eizirik, D.L.1
-
24
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
Eizirik D.L., Cardozo A.K., Cnop M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocrine Reviews 2008, 29(1):42-61.
-
(2008)
Endocrine Reviews
, vol.29
, Issue.1
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
25
-
-
0030005411
-
The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic beta cells
-
Eizirik D.L., Flodstrom M., Karlsen A.E., Welsh N. The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic beta cells. Diabetologia 1996, 39(8):875-890.
-
(1996)
Diabetologia
, vol.39
, Issue.8
, pp. 875-890
-
-
Eizirik, D.L.1
Flodstrom, M.2
Karlsen, A.E.3
Welsh, N.4
-
26
-
-
0035668779
-
A choice of death-The signal-transduction of immune-mediated beta-cell apoptosis
-
[erratum appears in Diabetologia. 2002 Jun;45(6):936.]
-
Eizirik D.L., Mandrup-Poulsen T. A choice of death-The signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001, 44(12):2115-2133. [erratum appears in Diabetologia. 2002 Jun;45(6):936.].
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
27
-
-
0031426764
-
Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM?
-
Eizirik D.L., Pavlovic D. Is there a role for nitric oxide in beta-cell dysfunction and damage in IDDM?. Diabetes/Metabolism Reviews 1997, 13(4):293-307.
-
(1997)
Diabetes/Metabolism Reviews
, vol.13
, Issue.4
, pp. 293-307
-
-
Eizirik, D.L.1
Pavlovic, D.2
-
28
-
-
0028296629
-
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation
-
Eizirik D.L., Sandler S., Welsh N., Cetkovic-Cvrlje M., Nieman A., Geller D.A., et al. Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. Journal of Clinical Investigation 1994, 93(5):1968-1974.
-
(1994)
Journal of Clinical Investigation
, vol.93
, Issue.5
, pp. 1968-1974
-
-
Eizirik, D.L.1
Sandler, S.2
Welsh, N.3
Cetkovic-Cvrlje, M.4
Nieman, A.5
Geller, D.A.6
-
29
-
-
0024390169
-
Endothelium-derived relaxing and contracting factors
-
Furchgott R.F., Vanhoutte P.M. Endothelium-derived relaxing and contracting factors. FASEB Journal 1989, 3(9):2007-2018.
-
(1989)
FASEB Journal
, vol.3
, Issue.9
, pp. 2007-2018
-
-
Furchgott, R.F.1
Vanhoutte, P.M.2
-
30
-
-
0024296032
-
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
-
Garthwaite J., Charles S.L., Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 1988, 336(6197):385-388.
-
(1988)
Nature
, vol.336
, Issue.6197
, pp. 385-388
-
-
Garthwaite, J.1
Charles, S.L.2
Chess-Williams, R.3
-
31
-
-
0024462440
-
NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices
-
Garthwaite J., Garthwaite G., Palmer R.M., Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. European Journal of Pharmacology 1989, 172(4-5):413-416.
-
(1989)
European Journal of Pharmacology
, vol.172
, Issue.4-5
, pp. 413-416
-
-
Garthwaite, J.1
Garthwaite, G.2
Palmer, R.M.3
Moncada, S.4
-
32
-
-
4143050290
-
The interaction between FOXO and SIRT1: Tipping the balance towards survival
-
Giannakou M.E., Partridge L. The interaction between FOXO and SIRT1: Tipping the balance towards survival. Trends in Cell Biology 2004, 14(8):408-412.
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.8
, pp. 408-412
-
-
Giannakou, M.E.1
Partridge, L.2
-
33
-
-
68049143316
-
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells
-
Grunnet L.G., Aikin R., Tonnesen M.F., Paraskevas S., Blaabjerg L., Storling J., et al. Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells. Diabetes 2009, 58(8):1807-1815.
-
(2009)
Diabetes
, vol.58
, Issue.8
, pp. 1807-1815
-
-
Grunnet, L.G.1
Aikin, R.2
Tonnesen, M.F.3
Paraskevas, S.4
Blaabjerg, L.5
Storling, J.6
-
34
-
-
79959618962
-
Bcl-2 proteins in diabetes: Mitochondrial pathways of beta-cell death and dysfunction
-
Gurzov E.N., Eizirik D.L. Bcl-2 proteins in diabetes: Mitochondrial pathways of beta-cell death and dysfunction. Trends in Cell Biology 2011, 21(7):424-431.
-
(2011)
Trends in Cell Biology
, vol.21
, Issue.7
, pp. 424-431
-
-
Gurzov, E.N.1
Eizirik, D.L.2
-
35
-
-
77953755226
-
P53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress
-
Gurzov E.N., Germano C.M., Cunha D.A., Ortis F., Vanderwinden J.M., Marchetti P., et al. p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress. Journal of Biological Chemistry 2010, 285(26):19910-19920.
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.26
, pp. 19910-19920
-
-
Gurzov, E.N.1
Germano, C.M.2
Cunha, D.A.3
Ortis, F.4
Vanderwinden, J.M.5
Marchetti, P.6
-
36
-
-
0030997703
-
Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
-
Heitmeier M.R., Scarim A.L., Corbett J.A. Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1. Journal of Biological Chemistry 1997, 272(21):13697-13704.
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.21
, pp. 13697-13704
-
-
Heitmeier, M.R.1
Scarim, A.L.2
Corbett, J.A.3
-
37
-
-
0032832969
-
Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans
-
Heitmeier M.R., Scarim A.L., Corbett J.A. Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. Journal of Biological Chemistry 1999, 274(41):29266-29273.
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.41
, pp. 29266-29273
-
-
Heitmeier, M.R.1
Scarim, A.L.2
Corbett, J.A.3
-
38
-
-
0023142137
-
L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells
-
Hibbs J.B., Vavrin Z., Taintor R.R. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. Journal of Immunology 1987, 138(2):550-565.
-
(1987)
Journal of Immunology
, vol.138
, Issue.2
, pp. 550-565
-
-
Hibbs, J.B.1
Vavrin, Z.2
Taintor, R.R.3
-
39
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang H., Tindall D.J. Dynamic FoxO transcription factors. Journal of Cell Science 2007, 120(Pt. 15):2479-2487.
-
(2007)
Journal of Cell Science
, vol.120
, Issue.PART. 15
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
40
-
-
70350451227
-
Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated beta-cells that is associated with irreversible DNA damage
-
Hughes K.J., Chambers K.T., Meares G.P., Corbett J.A. Nitric oxides mediates a shift from early necrosis to late apoptosis in cytokine-treated beta-cells that is associated with irreversible DNA damage. American Journal of Physiology. Endocrinology and Metabolism 2009, 297(5):E1187-E1196.
-
(2009)
American Journal of Physiology. Endocrinology and Metabolism
, vol.297
, Issue.5
-
-
Hughes, K.J.1
Chambers, K.T.2
Meares, G.P.3
Corbett, J.A.4
-
41
-
-
0024999802
-
Interleukin 1 inhibits insulin secretion from isolated rat pancreatic islets by a process that requires gene transcription and mRNA translation
-
Hughes J.H., Colca J.R., Easom R.A., Turk J., McDaniel M.L. Interleukin 1 inhibits insulin secretion from isolated rat pancreatic islets by a process that requires gene transcription and mRNA translation. Journal of Clinical Investigation 1990, 86(3):856-863.
-
(1990)
Journal of Clinical Investigation
, vol.86
, Issue.3
, pp. 856-863
-
-
Hughes, J.H.1
Colca, J.R.2
Easom, R.A.3
Turk, J.4
McDaniel, M.L.5
-
42
-
-
70350463891
-
Repair of nitric oxide-damaged DNA in beta-cells requires JNK-dependent GADD45alpha expression
-
Hughes K.J., Meares G.P., Chambers K.T., Corbett J.A. Repair of nitric oxide-damaged DNA in beta-cells requires JNK-dependent GADD45alpha expression. Journal of Biological Chemistry 2009, 284(40):27402-27408.
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.40
, pp. 27402-27408
-
-
Hughes, K.J.1
Meares, G.P.2
Chambers, K.T.3
Corbett, J.A.4
-
43
-
-
79953159885
-
FoxO1 and SIRT1 regulate beta-cell responses to nitric oxide
-
Hughes K.J., Meares G.P., Hansen P.A., Corbett J.A. FoxO1 and SIRT1 regulate beta-cell responses to nitric oxide. Journal of Biological Chemistry 2011, 286(10):8338-8348.
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.10
, pp. 8338-8348
-
-
Hughes, K.J.1
Meares, G.P.2
Hansen, P.A.3
Corbett, J.A.4
-
44
-
-
0025153863
-
Nitric oxide: A novel signal transduction mechanism for transcellular communication
-
Ignarro L.J. Nitric oxide: A novel signal transduction mechanism for transcellular communication. Hypertension 1990, 16(5):477-483.
-
(1990)
Hypertension
, vol.16
, Issue.5
, pp. 477-483
-
-
Ignarro, L.J.1
-
45
-
-
9244232272
-
Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: Inhibition by Bcl-2
-
Iwahashi H., Hanafusa T., Eguchi Y., Nakajima H., Miyagawa J., Itoh N., et al. Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: Inhibition by Bcl-2. Diabetologia 1996, 39(5):530-536.
-
(1996)
Diabetologia
, vol.39
, Issue.5
, pp. 530-536
-
-
Iwahashi, H.1
Hanafusa, T.2
Eguchi, Y.3
Nakajima, H.4
Miyagawa, J.5
Itoh, N.6
-
46
-
-
0030662226
-
Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms
-
Kim Y.M., Talanian R.V., Billiar T.R. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. Journal of Biological Chemistry 1997, 272(49):31138-31148.
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.49
, pp. 31138-31148
-
-
Kim, Y.M.1
Talanian, R.V.2
Billiar, T.R.3
-
47
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T., Bouchier-Hayes L., Chipuk J.E., Bonzon C., Sullivan B.A., Green D.R., et al. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Molecular Cell 2005, 17(4):525-535.
-
(2005)
Molecular Cell
, vol.17
, Issue.4
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
-
48
-
-
0028206337
-
The intraislet macrophage and type I diabetes
-
Lacy P.E. The intraislet macrophage and type I diabetes. Mount Sinai Journal of Medicine 1994, 61(2):170-174.
-
(1994)
Mount Sinai Journal of Medicine
, vol.61
, Issue.2
, pp. 170-174
-
-
Lacy, P.E.1
-
49
-
-
0025802116
-
Activation of intraislet lymphoid cells causes destruction of islet cells
-
Lacy P.E., Finke E.H. Activation of intraislet lymphoid cells causes destruction of islet cells. American Journal of Pathology 1991, 138(5):1183-1190.
-
(1991)
American Journal of Pathology
, vol.138
, Issue.5
, pp. 1183-1190
-
-
Lacy, P.E.1
Finke, E.H.2
-
50
-
-
63249112836
-
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway
-
Lee J.H., Song M.Y., Song E.K., Kim E.K., Moon W.S., Han M.K., et al. Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes 2009, 58(2):344-351.
-
(2009)
Diabetes
, vol.58
, Issue.2
, pp. 344-351
-
-
Lee, J.H.1
Song, M.Y.2
Song, E.K.3
Kim, E.K.4
Moon, W.S.5
Han, M.K.6
-
51
-
-
0031576527
-
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation
-
Li J., Billiar T.R., Talanian R.V., Kim Y.M. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochemical and Biophysical Research Communications 1997, 240(2):419-424.
-
(1997)
Biochemical and Biophysical Research Communications
, vol.240
, Issue.2
, pp. 419-424
-
-
Li, J.1
Billiar, T.R.2
Talanian, R.V.3
Kim, Y.M.4
-
52
-
-
0033949313
-
-/-)
-
-/-). Diabetes 2000, 49(7):1116-1122.
-
(2000)
Diabetes
, vol.49
, Issue.7
, pp. 1116-1122
-
-
Liu, D.1
Pavlovic, D.2
Chen, M.C.3
Flodstrom, M.4
Sandler, S.5
Eizirik, D.L.6
-
53
-
-
0029801229
-
Expression of the bcl-2 gene from a defective HSV-1 amplicon vector protects pancreatic beta-cells from apoptosis
-
Liu Y., Rabinovitch A., Suarez-Pinzon W., Muhkerjee B., Brownlee M., Edelstein D., et al. Expression of the bcl-2 gene from a defective HSV-1 amplicon vector protects pancreatic beta-cells from apoptosis. Human Gene Therapy 1996, 7(14):1719-1726.
-
(1996)
Human Gene Therapy
, vol.7
, Issue.14
, pp. 1719-1726
-
-
Liu, Y.1
Rabinovitch, A.2
Suarez-Pinzon, W.3
Muhkerjee, B.4
Brownlee, M.5
Edelstein, D.6
-
54
-
-
0035128723
-
Beta-cell apoptosis: Stimuli and signaling
-
Mandrup-Poulsen T. Beta-cell apoptosis: Stimuli and signaling. Diabetes 2001, 50(Suppl. 1):S58-S63.
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Mandrup-Poulsen, T.1
-
55
-
-
0022596377
-
Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans
-
Mandrup-Poulsen T., Bendtzen K., Nerup J., Dinarello C.A., Svenson M., Nielsen J.H. Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans. Diabetologia 1986, 29(1):63-67.
-
(1986)
Diabetologia
, vol.29
, Issue.1
, pp. 63-67
-
-
Mandrup-Poulsen, T.1
Bendtzen, K.2
Nerup, J.3
Dinarello, C.A.4
Svenson, M.5
Nielsen, J.H.6
-
56
-
-
0022234371
-
Cytokines cause functional and structural damage to isolated islets of Langerhans
-
Mandrup-Poulsen T., Bendtzen K., Nielsen J.H., Bendixen G., Nerup J. Cytokines cause functional and structural damage to isolated islets of Langerhans. Allergy 1985, 40(6):424-429.
-
(1985)
Allergy
, vol.40
, Issue.6
, pp. 424-429
-
-
Mandrup-Poulsen, T.1
Bendtzen, K.2
Nielsen, J.H.3
Bendixen, G.4
Nerup, J.5
-
57
-
-
77950352322
-
Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax
-
McKenzie M.D., Jamieson E., Jansen E.S., Scott C.L., Huang D.C., Bouillet P., et al. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax. Diabetes 2010, 59(3):644-652.
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 644-652
-
-
McKenzie, M.D.1
Jamieson, E.2
Jansen, E.S.3
Scott, C.L.4
Huang, D.C.5
Bouillet, P.6
-
58
-
-
77449100323
-
AMP-activated protein kinase attenuates nitric oxide induced beta-cell death
-
Meares G., Hughes K., Jaimes K., Salvatori A., Rhodes C., Corbett J. AMP-activated protein kinase attenuates nitric oxide induced beta-cell death. Journal of Biological Chemistry 2009, 285:3191-3200.
-
(2009)
Journal of Biological Chemistry
, vol.285
, pp. 3191-3200
-
-
Meares, G.1
Hughes, K.2
Jaimes, K.3
Salvatori, A.4
Rhodes, C.5
Corbett, J.6
-
59
-
-
78650518771
-
Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status
-
Mehmeti I., Lenzen S., Lortz S. Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status. Molecular and Cellular Endocrinology 2011, 332(1-2):88-96.
-
(2011)
Molecular and Cellular Endocrinology
, vol.332
, Issue.1-2
, pp. 88-96
-
-
Mehmeti, I.1
Lenzen, S.2
Lortz, S.3
-
60
-
-
0031577534
-
Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide
-
Mohr S., Zech B., Lapetina E.G., Brune B. Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide. Biochemical and Biophysical Research Communications 1997, 238(2):387-391.
-
(1997)
Biochemical and Biophysical Research Communications
, vol.238
, Issue.2
, pp. 387-391
-
-
Mohr, S.1
Zech, B.2
Lapetina, E.G.3
Brune, B.4
-
61
-
-
0024422967
-
The biological significance of nitric oxide formation from L-arginine
-
Moncada S., Palmer R.M., Higgs E.A. The biological significance of nitric oxide formation from L-arginine. Biochemical Society Transactions 1989, 17(4):642-644.
-
(1989)
Biochemical Society Transactions
, vol.17
, Issue.4
, pp. 642-644
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
62
-
-
0035845568
-
Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway
-
Oyadomari S., Takeda K., Takiguchi M., Gotoh T., Matsumoto M., Wada I., et al. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proceedings of the National Academy of Sciences of the United States of America 2001, 98(19):10845-10850.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10845-10850
-
-
Oyadomari, S.1
Takeda, K.2
Takiguchi, M.3
Gotoh, T.4
Matsumoto, M.5
Wada, I.6
-
63
-
-
84875674753
-
The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis
-
Padgett L.E., Broniowska K.A., Hansen P.A., Corbett J.A., Tse H.M. The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis. Annals of the New York Academy of Sciences 2013, 1281:16-35.
-
(2013)
Annals of the New York Academy of Sciences
, vol.1281
, pp. 16-35
-
-
Padgett, L.E.1
Broniowska, K.A.2
Hansen, P.A.3
Corbett, J.A.4
Tse, H.M.5
-
64
-
-
84872194492
-
Endoplasmic reticulum stress, pancreatic beta-cell degeneration, and diabetes
-
Papa F.R. Endoplasmic reticulum stress, pancreatic beta-cell degeneration, and diabetes. Cold Spring Harbor Perspectives in Medicine 2012, 2(9):a007666.
-
(2012)
Cold Spring Harbor Perspectives in Medicine
, vol.2
, Issue.9
-
-
Papa, F.R.1
-
65
-
-
0033778471
-
Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells
-
Pavlovic D., Andersen N.A., Mandrup-Poulsen T., Eizirik D.L. Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells. European Cytokine Network 2000, 11(2):267-274.
-
(2000)
European Cytokine Network
, vol.11
, Issue.2
, pp. 267-274
-
-
Pavlovic, D.1
Andersen, N.A.2
Mandrup-Poulsen, T.3
Eizirik, D.L.4
-
66
-
-
0028789356
-
Nitric oxide synthase isozymes antibodies
-
Pollock J.S., Forstermann U., Tracey W.R., Nakane M. Nitric oxide synthase isozymes antibodies. Histochemical Journal 1995, 27(10):738-744.
-
(1995)
Histochemical Journal
, vol.27
, Issue.10
, pp. 738-744
-
-
Pollock, J.S.1
Forstermann, U.2
Tracey, W.R.3
Nakane, M.4
-
69
-
-
3042578787
-
Repair of cytokine-induced DNA damage in cultured rat islets of Langerhans
-
Rosales A.L., Cunningham J.M., Bone A.J., Green I.C., Green M.H. Repair of cytokine-induced DNA damage in cultured rat islets of Langerhans. Free Radical Research 2004, 38(7):665-674.
-
(2004)
Free Radical Research
, vol.38
, Issue.7
, pp. 665-674
-
-
Rosales, A.L.1
Cunningham, J.M.2
Bone, A.J.3
Green, I.C.4
Green, M.H.5
-
70
-
-
0034456628
-
Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells
-
Saldeen J. Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells. Endocrinology 2000, 141(6):2003-2010.
-
(2000)
Endocrinology
, vol.141
, Issue.6
, pp. 2003-2010
-
-
Saldeen, J.1
-
71
-
-
0035877087
-
Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis
-
Saldeen J., Lee J.C., Welsh N. Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis. Biochemical Pharmacology 2001, 61(12):1561-1569.
-
(2001)
Biochemical Pharmacology
, vol.61
, Issue.12
, pp. 1561-1569
-
-
Saldeen, J.1
Lee, J.C.2
Welsh, N.3
-
72
-
-
0030684124
-
Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1beta
-
Scarim A.L., Heitmeier M.R., Corbett J.A. Irreversible inhibition of metabolic function and islet destruction after a 36-hour exposure to interleukin-1beta. Endocrinology 1997, 138(12):5301-5307.
-
(1997)
Endocrinology
, vol.138
, Issue.12
, pp. 5301-5307
-
-
Scarim, A.L.1
Heitmeier, M.R.2
Corbett, J.A.3
-
73
-
-
0031757110
-
Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets
-
Scarim A.L., Heitmeier M.R., Corbett J.A. Heat shock inhibits cytokine-induced nitric oxide synthase expression by rat and human islets. Endocrinology 1998, 139(12):5050-5057.
-
(1998)
Endocrinology
, vol.139
, Issue.12
, pp. 5050-5057
-
-
Scarim, A.L.1
Heitmeier, M.R.2
Corbett, J.A.3
-
74
-
-
0042315383
-
Role for c-Jun N-terminal kinase in beta-cell recovery from nitric oxide-mediated damage
-
Scarim A.L., Nishimoto S.Y., Weber S.M., Corbett J.A. Role for c-Jun N-terminal kinase in beta-cell recovery from nitric oxide-mediated damage. Endocrinology 2003, 144(8):3415-3422.
-
(2003)
Endocrinology
, vol.144
, Issue.8
, pp. 3415-3422
-
-
Scarim, A.L.1
Nishimoto, S.Y.2
Weber, S.M.3
Corbett, J.A.4
-
76
-
-
0025685395
-
Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism
-
Southern C., Schulster D., Green I.C. Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism. FEBS Letters 1990, 276(1-2):42-44.
-
(1990)
FEBS Letters
, vol.276
, Issue.1-2
, pp. 42-44
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
77
-
-
0023002314
-
Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans
-
Spinas G.A., Mandrup-Poulsen T., Molvig J., Baek L., Bendtzen K., Dinarello C.A., et al. Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans. Acta Endocrinologica 1986, 113(4):551-558.
-
(1986)
Acta Endocrinologica
, vol.113
, Issue.4
, pp. 551-558
-
-
Spinas, G.A.1
Mandrup-Poulsen, T.2
Molvig, J.3
Baek, L.4
Bendtzen, K.5
Dinarello, C.A.6
-
78
-
-
33644843857
-
Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1
-
Steer S.A., Scarim A.L., Chambers K.T., Corbett J.A. Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1. PLoS Medicine 2006, 3(2):e17.
-
(2006)
PLoS Medicine
, vol.3
, Issue.2
-
-
Steer, S.A.1
Scarim, A.L.2
Chambers, K.T.3
Corbett, J.A.4
-
79
-
-
26244436171
-
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
-
Storling J., Binzer J., Andersson A.K., Zullig R.A., Tonnesen M., Lehmann R., et al. Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt. Diabetologia 2005, 48(10):2039-2050.
-
(2005)
Diabetologia
, vol.48
, Issue.10
, pp. 2039-2050
-
-
Storling, J.1
Binzer, J.2
Andersson, A.K.3
Zullig, R.A.4
Tonnesen, M.5
Lehmann, R.6
-
80
-
-
0032579373
-
Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis
-
Takamura T., Kato I., Kimura N., Nakazawa T., Yonekura H., Takasawa S., et al. Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis. Journal of Biological Chemistry 1998, 273(5):2493-2496.
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.5
, pp. 2493-2496
-
-
Takamura, T.1
Kato, I.2
Kimura, N.3
Nakazawa, T.4
Yonekura, H.5
Takasawa, S.6
-
81
-
-
80053245530
-
NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic beta-cells
-
Tamura Y., Chiba Y., Tanioka T., Shimizu N., Shinozaki S., Yamada M., et al. NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic beta-cells. FEBS Letters 2011, 585(19):3058-3064.
-
(2011)
FEBS Letters
, vol.585
, Issue.19
, pp. 3058-3064
-
-
Tamura, Y.1
Chiba, Y.2
Tanioka, T.3
Shimizu, N.4
Shinozaki, S.5
Yamada, M.6
-
82
-
-
80855124182
-
Intracellular pathways of pancreatic beta-cell apoptosis in type 1 diabetes
-
Thomas H.E., Kay T.W. Intracellular pathways of pancreatic beta-cell apoptosis in type 1 diabetes. Diabetes/Metabolism Research and Reviews 2011, 27(8):790-796.
-
(2011)
Diabetes/Metabolism Research and Reviews
, vol.27
, Issue.8
, pp. 790-796
-
-
Thomas, H.E.1
Kay, T.W.2
-
83
-
-
0037645822
-
Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy
-
Tran V.V., Chen G., Newgard C.B., Hohmeier H.E. Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy. Diabetes 2003, 52(6):1423-1432.
-
(2003)
Diabetes
, vol.52
, Issue.6
, pp. 1423-1432
-
-
Tran, V.V.1
Chen, G.2
Newgard, C.B.3
Hohmeier, H.E.4
-
84
-
-
34548381411
-
Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes
-
Wang M., Zhao X.R., Wang P., Li L., Dai Y., Huang H., et al. Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes. International Journal of Biochemistry and Cell Biology 2007, 39(11):2076-2082.
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.11
, pp. 2076-2082
-
-
Wang, M.1
Zhao, X.R.2
Wang, P.3
Li, L.4
Dai, Y.5
Huang, H.6
-
85
-
-
8544267219
-
PPARgamma ligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling
-
Weber S.M., Chambers K.T., Bensch K.G., Scarim A.L., Corbett J.A. PPARgamma ligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling. American Journal of Physiology. Endocrinology and Metabolism 2004, 287(6):E1171-E1177.
-
(2004)
American Journal of Physiology. Endocrinology and Metabolism
, vol.287
, Issue.6
-
-
Weber, S.M.1
Chambers, K.T.2
Bensch, K.G.3
Scarim, A.L.4
Corbett, J.A.5
-
86
-
-
0037404327
-
Inhibition of IFN-gamma -induced STAT1 activation by 15- deoxy-Delta 12,14-prostaglandin J2
-
Weber S.M., Scarim A.L., Corbett J.A. Inhibition of IFN-gamma -induced STAT1 activation by 15- deoxy-Delta 12,14-prostaglandin J2. American Journal of Physiology. Endocrinology and Metabolism 2003, 284(5):E883-E891.
-
(2003)
American Journal of Physiology. Endocrinology and Metabolism
, vol.284
, Issue.5
-
-
Weber, S.M.1
Scarim, A.L.2
Corbett, J.A.3
-
87
-
-
0025833992
-
Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase
-
Welsh N., Eizirik D.L., Bendtzen K., Sandler S. Interleukin-1 beta-induced nitric oxide production in isolated rat pancreatic islets requires gene transcription and may lead to inhibition of the Krebs cycle enzyme aconitase. Endocrinology 1991, 129(6):3167-3173.
-
(1991)
Endocrinology
, vol.129
, Issue.6
, pp. 3167-3173
-
-
Welsh, N.1
Eizirik, D.L.2
Bendtzen, K.3
Sandler, S.4
-
88
-
-
0029401861
-
Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: Implications for the pathogenesis of insulin-dependent diabetes mellitus
-
Welsh N., Margulis B., Borg L.A., Wiklund H.J., Saldeen J., Flodstrom M., et al. Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: Implications for the pathogenesis of insulin-dependent diabetes mellitus. Molecular Medicine 1995, 1(7):806-820.
-
(1995)
Molecular Medicine
, vol.1
, Issue.7
, pp. 806-820
-
-
Welsh, N.1
Margulis, B.2
Borg, L.A.3
Wiklund, H.J.4
Saldeen, J.5
Flodstrom, M.6
-
89
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S.N., Fletcher J.I., Kaufmann T., van Delft M.F., Chen L., Czabotar P.E., et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 2007, 315(5813):856-859.
-
(2007)
Science
, vol.315
, Issue.5813
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
-
90
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle R.J., Strasser A. The BCL-2 protein family: Opposing activities that mediate cell death. Nature Reviews. Molecular Cell Biology 2008, 9(1):47-59.
-
(2008)
Nature Reviews. Molecular Cell Biology
, vol.9
, Issue.1
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
|