-
1
-
-
0034253588
-
Evolution and function of ubiquitin-like protein-conjugation systems
-
Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol 2000; 2: E153-E157.
-
(2000)
Nat Cell Biol
, vol.2
-
-
Hochstrasser, M.1
-
2
-
-
0035170874
-
Solution structure of ThiS and implications for the evolutionary roots of ubiquitin
-
Wang C, Xi J, Begley TP, Nicholson LK. Solution structure of ThiS and implications for the evolutionary roots of ubiquitin. Nat Struct Mol Biol 2001; 8: 47-51.
-
(2001)
Nat Struct Mol Biol
, vol.8
, pp. 47-51
-
-
Wang, C.1
Xi, J.2
Begley, T.P.3
Nicholson, L.K.4
-
3
-
-
2442437350
-
Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells
-
Goldstein G, Scheid M, Hammerling U, Boyse EA, Schlesinger DH, Niall HD. Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc Natl Acad Sci USA 1975; 72: 11-15.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 11-15
-
-
Goldstein, G.1
Scheid, M.2
Hammerling, U.3
Boyse, E.A.4
Schlesinger, D.H.5
Niall, H.D.6
-
4
-
-
0035293622
-
Protein regulation by monoubiquitin
-
Hicke L. Protein regulation by monoubiquitin. Nat Rev Mol Cell Biol 2001; 2: 195-201.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 195-201
-
-
Hicke, L.1
-
6
-
-
0021099710
-
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown
-
Hershko A, Heller H, Elias S, Ciechanover A. Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown. J Biol Chem 1983; 258: 8206-8214.
-
(1983)
J Biol Chem
, vol.258
, pp. 8206-8214
-
-
Hershko, A.1
Heller, H.2
Elias, S.3
Ciechanover, A.4
-
7
-
-
9644268864
-
Mechanism and function of deubiquitinating enzymes
-
Amerik AY, Hochstrasser M. Mechanism and function of deubiquitinating enzymes. Biochim Biophys Acta 2004; 1695: 189-207.
-
(2004)
Biochim Biophys Acta
, vol.1695
, pp. 189-207
-
-
Amerik, A.Y.1
Hochstrasser, M.2
-
8
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako T, Kamei K, Murata S, Kato M, Fukumoto H, Kanie M et al. A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J 2006; 25: 4877-4887.
-
(2006)
EMBO J
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
Kamei, K.2
Murata, S.3
Kato, M.4
Fukumoto, H.5
Kanie, M.6
-
9
-
-
0017601447
-
Isopeptide linkage between nonhistone and histone-2A polypeptides of chromosomal conjugate-proteins-A24
-
Goldknopf IL, Busch H. Isopeptide linkage between nonhistone and histone-2A polypeptides of chromosomal conjugate-proteins-A24. Proc Natl Acad Sci USA 1977; 74: 864-868.
-
(1977)
Proc Natl Acad Sci USA
, vol.74
, pp. 864-868
-
-
Goldknopf, I.L.1
Busch, H.2
-
10
-
-
0041706156
-
A proteomics approach to understanding protein ubiquitination
-
Peng JM, Schwartz D, Elias JE, Thoreen CC, Cheng DM, Marsischky G et al. A proteomics approach to understanding protein ubiquitination. Nat Biotechnol 2003; 21: 921-926.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 921-926
-
-
Peng, J.M.1
Schwartz, D.2
Elias, J.E.3
Thoreen, C.C.4
Cheng, D.M.5
Marsischky, G.6
-
11
-
-
0036922992
-
Structural properties of polyubiquitin chains in solution
-
Varadan R, Walker O, Pickart C, Fushman D. Structural properties of polyubiquitin chains in solution. J Mol Biol 2002; 324: 637-647.
-
(2002)
J Mol Biol
, vol.324
, pp. 637-647
-
-
Varadan, R.1
Walker, O.2
Pickart, C.3
Fushman, D.4
-
12
-
-
73649116305
-
Exploring the linkage dependence of polyubiquitin conformations using molecular modeling
-
Fushman D, Walker O. Exploring the linkage dependence of polyubiquitin conformations using molecular modeling. J Mol Biol 2010; 395: 803-814.
-
(2010)
J Mol Biol
, vol.395
, pp. 803-814
-
-
Fushman, D.1
Walker, O.2
-
13
-
-
34547130325
-
Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages
-
Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D et al. Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. J Biol Chem 2007; 282: 17375-17386.
-
(2007)
J Biol Chem
, vol.282
, pp. 17375-17386
-
-
Kim, H.T.1
Kim, K.P.2
Lledias, F.3
Kisselev, A.F.4
Scaglione, K.M.5
Skowyra, D.6
-
14
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW. Defining the human deubiquitinating enzyme interaction landscape. Cell 2009; 138: 389-403.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
15
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S. Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 2009; 10: 550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
16
-
-
72149130935
-
The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome
-
Jacobson AD, Zhang NY, Xu P, Han KJ, Noone S, Peng J et al. The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome. J Biol Chem 2009; 284: 35485-35494.
-
(2009)
J Biol Chem
, vol.284
, pp. 35485-35494
-
-
Jacobson, A.D.1
Zhang, N.Y.2
Xu, P.3
Han, K.J.4
Noone, S.5
Peng, J.6
-
17
-
-
71149107057
-
Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening
-
Peth A, Besche HC, Goldberg AL. Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening. Mol Cell 2009; 36: 794-804.
-
(2009)
Mol Cell
, vol.36
, pp. 794-804
-
-
Peth, A.1
Besche, H.C.2
Goldberg, A.L.3
-
18
-
-
78649289427
-
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation
-
Peth A, Uchiki T, Goldberg AL. ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation. Mol Cell 2010; 40: 671-681.
-
(2010)
Mol Cell
, vol.40
, pp. 671-681
-
-
Peth, A.1
Uchiki, T.2
Goldberg, A.L.3
-
19
-
-
0029119522
-
A proteolytic pathway that recognizes ubiquitin as a degradation signal
-
Johnson ES, Ma PCM, Ota IM, Varshavsky A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. J Biol Chem 1995; 270: 17442-17456.
-
(1995)
J Biol Chem
, vol.270
, pp. 17442-17456
-
-
Johnson, E.S.1
Ma, P.C.M.2
Ota, I.M.3
Varshavsky, A.4
-
20
-
-
0035891863
-
Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex
-
Matilla A, Gorbea C, Einum DD, Townsend J, Michalik A, van Broeckhoven C et al. Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex. Hum Mol Genet 2001; 10: 2821-2831.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2821-2831
-
-
Matilla, A.1
Gorbea, C.2
Einum, D.D.3
Townsend, J.4
Michalik, A.5
Van Broeckhoven, C.6
-
21
-
-
62649104153
-
K63-specific deubiquitination by two JAMM/MPN\+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
-
Cooper EM, Cutcliffe C, Kristiansen TZ, Pandey A, Pickart CM, Cohen RE. K63-specific deubiquitination by two JAMM/MPN\+ complexes: BRISC-associated Brcc36 and proteasomal Poh1. EMBO J 2009; 28: 621-631.
-
(2009)
EMBO J
, vol.28
, pp. 621-631
-
-
Cooper, E.M.1
Cutcliffe, C.2
Kristiansen, T.Z.3
Pandey, A.4
Pickart, C.M.5
Cohen, R.E.6
-
22
-
-
63049125531
-
Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
-
Xu P, Duong DM, Seyfried NT, Cheng DM, Xie Y, Robert J et al. Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 2009; 137: 133-145.
-
(2009)
Cell
, vol.137
, pp. 133-145
-
-
Xu, P.1
Duong, D.M.2
Seyfried, N.T.3
Cheng, D.M.4
Xie, Y.5
Robert, J.6
-
23
-
-
77956903406
-
Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase
-
Virdee S, Ye Y, Nguyen DP, Komander D, Chin JW. Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase. Nat Chem Biol 2010; 6: 750-757.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 750-757
-
-
Virdee, S.1
Ye, Y.2
Nguyen, D.P.3
Komander, D.4
Chin, J.W.5
-
24
-
-
1042278177
-
Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase
-
Nishikawa H, Ooka S, Sato K, Arima K, Okamoto J, Klevit RE et al. Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase. J Biol Chem 2003; 279: 3916-3924.
-
(2003)
J Biol Chem
, vol.279
, pp. 3916-3924
-
-
Nishikawa, H.1
Ooka, S.2
Sato, K.3
Arima, K.4
Okamoto, J.5
Klevit, R.E.6
-
25
-
-
33751515474
-
The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity
-
Ben-Saadon R, Zaaroor D, Ziv T, Ciechanover A. The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. Mol Cell 2006; 24: 701-711.
-
(2006)
Mol Cell
, vol.24
, pp. 701-711
-
-
Ben-Saadon, R.1
Zaaroor, D.2
Ziv, T.3
Ciechanover, A.4
-
26
-
-
77957284673
-
Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex
-
Patterson-Fortin J, Shao G, Bretscher H, Messick TE, Greenberg RA. Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex. J Biol Chem 2010; 285: 30971-30981.
-
(2010)
J Biol Chem
, vol.285
, pp. 30971-30981
-
-
Patterson-Fortin, J.1
Shao, G.2
Bretscher, H.3
Messick, T.E.4
Greenberg, R.A.5
-
27
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 2003; 421: 961-966.
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
28
-
-
0346059615
-
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage
-
Mochan TA, Venere M, DiTullio Jr. RA, Halazonetis TD. 53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage. Cancer Res 2003; 63: 8586-8591.
-
(2003)
Cancer Res
, vol.63
, pp. 8586-8591
-
-
Mochan, T.A.1
Venere, M.2
DiTullio Jr., R.A.3
Halazonetis, T.D.4
-
29
-
-
0038496703
-
Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control
-
Lou Z, Chini CC, Minter-Dykhouse K, Chen J. Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control. J Biol Chem 2003; 278: 13599-13602.
-
(2003)
J Biol Chem
, vol.278
, pp. 13599-13602
-
-
Lou, Z.1
Chini, C.C.2
Minter-Dykhouse, K.3
Chen, J.4
-
30
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB et al. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007; 131: 901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
-
31
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, Sweeney FD et al. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 2007; 318: 1637-1640.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
-
32
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007; 131: 887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
-
33
-
-
36749025467
-
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
Wang B, Elledge SJ. Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc Natl Acad Sci USA 2007; 104: 20759-20763.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
Elledge, S.J.2
-
34
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009; 136: 435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
-
35
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES et al. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009; 136: 420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
-
36
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP et al. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 2007; 316: 1194-1198.
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
-
37
-
-
67349168142
-
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
-
Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X et al. RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol 2009; 11: 592-603.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 592-603
-
-
Huang, J.1
Huen, M.S.2
Kim, H.3
Leung, C.C.4
Glover, J.N.5
Yu, X.6
-
38
-
-
70349944658
-
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response
-
Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM et al. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response. J Cell Biol 2009; 186: 835-847.
-
(2009)
J Cell Biol
, vol.186
, pp. 835-847
-
-
Marteijn, J.A.1
Bekker-Jensen, S.2
Mailand, N.3
Lans, H.4
Schwertman, P.5
Gourdin, A.M.6
-
39
-
-
84859895529
-
RNF8-and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
-
Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, Mer G et al. RNF8-and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J 2012; 31: 1865-1878.
-
(2012)
EMBO J
, vol.31
, pp. 1865-1878
-
-
Mallette, F.A.1
Mattiroli, F.2
Cui, G.3
Young, L.C.4
Hendzel, M.J.5
Mer, G.6
-
40
-
-
84867101138
-
The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response
-
Butler LR, Densham RM, Jia J, Garvin AJ, Stone HR, Shah V et al. The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response. EMBO J 2012; 31: 3918-3934.
-
(2012)
EMBO J
, vol.31
, pp. 3918-3934
-
-
Butler, L.R.1
Densham, R.M.2
Jia, J.3
Garvin, A.J.4
Stone, H.R.5
Shah, V.6
-
41
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli F, Vissers JH, van Dijk WJ, Ikpa P, Citterio E, Vermeulen W et al. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell 2012; 150: 1182-1195.
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
Vissers, J.H.2
Van Dijk, W.J.3
Ikpa, P.4
Citterio, E.5
Vermeulen, W.6
-
42
-
-
53249113644
-
RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites
-
Yan J, Jetten AM. RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites. Cancer Lett 2008; 271: 179-190.
-
(2008)
Cancer Lett
, vol.271
, pp. 179-190
-
-
Yan, J.1
Jetten, A.M.2
-
43
-
-
84863315246
-
Rap80 is important for genomic stability and is required for stabilizing the BRCA1-A complex at DNA damage sites in vivo
-
Wu J, Liu C, Chen J, Yu X. Rap80 is important for genomic stability and is required for stabilizing the BRCA1-A complex at DNA damage sites in vivo. J Biol Chem 2012; 287: 22919-22926.
-
(2012)
J Biol Chem
, vol.287
, pp. 22919-22926
-
-
Wu, J.1
Liu, C.2
Chen, J.3
Yu, X.4
-
44
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B et al. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 2007; 316: 1198-1202.
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
Culhane, A.C.4
Moreau, L.A.5
Xia, B.6
-
45
-
-
84867115508
-
RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1
-
Nakada S, Yonamine RM, Matsuo K. RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1. Cancer Res 2012; 72: 4974-4983.
-
(2012)
Cancer Res
, vol.72
, pp. 4974-4983
-
-
Nakada, S.1
Yonamine, R.M.2
Matsuo, K.3
-
46
-
-
79952694801
-
RAD51-independent inverted-repeat recombination by a strand-annealing mechanism
-
Mott C, Symington LS. RAD51-independent inverted-repeat recombination by a strand-annealing mechanism. DNA Repair 2011; 10: 408-415.
-
(2011)
DNA Repair
, vol.10
, pp. 408-415
-
-
Mott, C.1
Symington, L.S.2
-
47
-
-
0035893241
-
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange
-
Sigurdsson S, Van Komen S, Bussen W, Schild D, Albala JS, Sung P. Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes Develop 2001; 15: 3308-3318.
-
(2001)
Genes Develop
, vol.15
, pp. 3308-3318
-
-
Sigurdsson, S.1
Van Komen, S.2
Bussen, W.3
Schild, D.4
Albala, J.S.5
Sung, P.6
-
48
-
-
77955475870
-
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex
-
Dou H, Huang C, Singh M, Carpenter PB, Yeh ET. Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Mol Cell 2010; 39: 333-345.
-
(2010)
Mol Cell
, vol.39
, pp. 333-345
-
-
Dou, H.1
Huang, C.2
Singh, M.3
Carpenter, P.B.4
Yeh, E.T.5
-
49
-
-
84861765707
-
RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair
-
Galanty Y, Belotserkovskaya R, Coates J, Jackson SP. RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. Genes Develop 2012; 26: 1179-1195.
-
(2012)
Genes Develop
, vol.26
, pp. 1179-1195
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Jackson, S.P.4
-
50
-
-
84863846456
-
Sumoylation of MDC1 is important for proper DNA damage response
-
Luo K, Zhang H, Wang L, Yuan J, Lou Z. Sumoylation of MDC1 is important for proper DNA damage response. EMBO J 2012; 31: 3008-3019.
-
(2012)
EMBO J
, vol.31
, pp. 3008-3019
-
-
Luo, K.1
Zhang, H.2
Wang, L.3
Yuan, J.4
Lou, Z.5
-
51
-
-
84861784690
-
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage
-
Yin Y, Seifert A, Chua JS, Maure JF, Golebiowski F, Hay RT. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. Genes Develop 2012; 26: 1196-1208.
-
(2012)
Genes Develop
, vol.26
, pp. 1196-1208
-
-
Yin, Y.1
Seifert, A.2
Chua, J.S.3
Maure, J.F.4
Golebiowski, F.5
Hay, R.T.6
-
52
-
-
84873704658
-
RNF4 is required for DNA double-strand break repair in vivo
-
Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, Sotiropoulou P et al. RNF4 is required for DNA double-strand break repair in vivo. Cell Death Differ 2012; 20: 490-502.
-
(2012)
Cell Death Differ
, vol.20
, pp. 490-502
-
-
Vyas, R.1
Kumar, R.2
Clermont, F.3
Helfricht, A.4
Kalev, P.5
Sotiropoulou, P.6
-
53
-
-
33746766974
-
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
-
Zhang D, Zaugg K, Mak TW, Elledge SJ. A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 2006; 126: 529-542.
-
(2006)
Cell
, vol.126
, pp. 529-542
-
-
Zhang, D.1
Zaugg, K.2
Mak, T.W.3
Elledge, S.J.4
-
54
-
-
35848942129
-
Fbw7 and Usp28 regulate Myc protein stability in response to DNA damage
-
Popov N, Herold S, Llamazares M, Schulein C, Eilers M. Fbw7 and Usp28 regulate Myc protein stability in response to DNA damage. Cell Cycle 2007; 6: 2327-2331.
-
(2007)
Cell Cycle
, vol.6
, pp. 2327-2331
-
-
Popov, N.1
Herold, S.2
Llamazares, M.3
Schulein, C.4
Eilers, M.5
-
55
-
-
36049036216
-
Human USP3 is a chromatin modifier required for S phase progression and genome stability
-
Nicassio F, Corrado N, Vissers JH, Areces LB, Bergink S, Marteijn JA et al. Human USP3 is a chromatin modifier required for S phase progression and genome stability. Curr Biol 2007; 17: 1972-1977.
-
(2007)
Curr Biol
, vol.17
, pp. 1972-1977
-
-
Nicassio, F.1
Corrado, N.2
Vissers, J.H.3
Areces, L.B.4
Bergink, S.5
Marteijn, J.A.6
-
56
-
-
35548986309
-
Regulation of cell cycle progression and gene expression by H2A deubiquitination
-
Joo HY, Zhai L, Yang C, Nie S, Erdjument-Bromage H, Tempst P et al. Regulation of cell cycle progression and gene expression by H2A deubiquitination. Nature 2007; 449: 1068-1072.
-
(2007)
Nature
, vol.449
, pp. 1068-1072
-
-
Joo, H.Y.1
Zhai, L.2
Yang, C.3
Nie, S.4
Erdjument-Bromage, H.5
Tempst, P.6
-
57
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC et al. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 2010; 466: 941-946.
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
-
58
-
-
84862806447
-
The mechanism of OTUB1-mediated inhibition of ubiquitination
-
Wiener R, Zhang X, Wang T, Wolberger C. The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature 2012; 483: 618-622.
-
(2012)
Nature
, vol.483
, pp. 618-622
-
-
Wiener, R.1
Zhang, X.2
Wang, T.3
Wolberger, C.4
-
59
-
-
84856801739
-
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function
-
Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF et al. OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. Mol Cell 2012; 45: 384-397.
-
(2012)
Mol Cell
, vol.45
, pp. 384-397
-
-
Juang, Y.C.1
Landry, M.C.2
Sanches, M.3
Vittal, V.4
Leung, C.C.5
Ceccarelli, D.F.6
-
60
-
-
84864386119
-
Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13
-
Sato Y, Yamagata A, Goto-Ito S, Kubota K, Miyamoto R, Nakada S et al. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13. J Biol Chem 2012; 287: 25860-25868.
-
(2012)
J Biol Chem
, vol.287
, pp. 25860-25868
-
-
Sato, Y.1
Yamagata, A.2
Goto-Ito, S.3
Kubota, K.4
Miyamoto, R.5
Nakada, S.6
-
61
-
-
77957260099
-
The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments
-
Feng L, Wang J, Chen J. The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J Biol Chem 2010; 285: 30982-30988.
-
(2010)
J Biol Chem
, vol.285
, pp. 30982-30988
-
-
Feng, L.1
Wang, J.2
Chen, J.3
-
62
-
-
62549140202
-
-
Shao G, Lilli DR, Patterson-Fortin J, Coleman KA, Morrissey DE, Greenberg RA. The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks. Proc Natl Acad Sci USA 2009; 106: 3166-3171.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3166-3171
-
-
Shao, G.1
Lilli, D.R.2
Patterson-Fortin, J.3
Coleman, K.A.4
Morrissey, D.E.5
-
63
-
-
82955233157
-
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
-
Acs K, Luijsterburg MS, Ackermann L, Salomons FA, Hoppe T, Dantuma NP. The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat Struct Mol Biol 2011; 18: 1345-1350.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1345-1350
-
-
Acs, K.1
Luijsterburg, M.S.2
Ackermann, L.3
Salomons, F.A.4
Hoppe, T.5
Dantuma, N.P.6
-
64
-
-
80455145246
-
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
-
Meerang M, Ritz D, Paliwal S, Garajova Z, Bosshard M, Mailand N et al. The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat Cell Biol 2011; 13: 1376-1382.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1376-1382
-
-
Meerang, M.1
Ritz, D.2
Paliwal, S.3
Garajova, Z.4
Bosshard, M.5
Mailand, N.6
-
65
-
-
33645731673
-
A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling
-
Dantuma NP, Groothuis TA, Salomons FA, Neefjes J. A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling. J Cell Biol 2006; 173: 19-26.
-
(2006)
J Cell Biol
, vol.173
, pp. 19-26
-
-
Dantuma, N.P.1
Groothuis, T.A.2
Salomons, F.A.3
Neefjes, J.4
-
66
-
-
57649130600
-
Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation
-
Shi W, Ma Z, Willers H, Akhtar K, Scott SP, Zhang J et al. Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation. J Biol Chem 2008; 283: 31608-31616.
-
(2008)
J Biol Chem
, vol.283
, pp. 31608-31616
-
-
Shi, W.1
Ma, Z.2
Willers, H.3
Akhtar, K.4
Scott, S.P.5
Zhang, J.6
-
67
-
-
34548807121
-
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells
-
Murakawa Y, Sonoda E, Barber LJ, Zeng W, Yokomori K, Kimura H et al. Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res 2007; 67: 8536-8543.
-
(2007)
Cancer Res
, vol.67
, pp. 8536-8543
-
-
Murakawa, Y.1
Sonoda, E.2
Barber, L.J.3
Zeng, W.4
Yokomori, K.5
Kimura, H.6
-
68
-
-
34547628200
-
Proteasome function is required for DNA damage response and fanconi anemia pathway activation
-
Jacquemont C, Taniguchi T. Proteasome function is required for DNA damage response and fanconi anemia pathway activation. Cancer Res 2007; 67: 7395-7405.
-
(2007)
Cancer Res
, vol.67
, pp. 7395-7405
-
-
Jacquemont, C.1
Taniguchi, T.2
-
69
-
-
36749022182
-
The proteasome is involved in determining differential utilization of double-strand break repair pathways
-
Gudmundsdottir K, Lord CJ, Ashworth A. The proteasome is involved in determining differential utilization of double-strand break repair pathways. Oncogene 2007; 26: 7601-7606.
-
(2007)
Oncogene
, vol.26
, pp. 7601-7606
-
-
Gudmundsdottir, K.1
Lord, C.J.2
Ashworth, A.3
-
70
-
-
77649196564
-
Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair
-
Ben-Aroya S, Agmon N, Yuen K, Kwok T, McManus K, Kupiec M et al. Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair. PLoS Genet 2010; 6: e1000852.
-
(2010)
PLoS Genet
, vol.6
-
-
Ben-Aroya, S.1
Agmon, N.2
Yuen, K.3
Kwok, T.4
McManus, K.5
Kupiec, M.6
-
71
-
-
65849488473
-
Regulation of ErbB2 receptor status by the proteasomal DUB POH1
-
Liu H, Buus R, Clague MJ, Urbe S. Regulation of ErbB2 receptor status by the proteasomal DUB POH1. PLoS ONE 2009; 4: e5544.
-
(2009)
PLoS ONE
, vol.4
-
-
Liu, H.1
Buus, R.2
Clague, M.J.3
Urbe, S.4
-
72
-
-
0344629427
-
Ubiquitin depletion as a key mediator of toxicity by translational inhibitors
-
Hanna J, Leggett DS, Finley D. Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Mol Cell Biol 2003; 23: 9251-9261.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9251-9261
-
-
Hanna, J.1
Leggett, D.S.2
Finley, D.3
-
73
-
-
49749093073
-
Ku80 removal from DNA through double strand break-induced ubiquitylation
-
Postow L, Ghenoiu C, Woo EM, Krutchinsky AN, Chait BT, Funabiki H. Ku80 removal from DNA through double strand break-induced ubiquitylation. J Cell Biol 2008; 182: 467-479.
-
(2008)
J Cell Biol
, vol.182
, pp. 467-479
-
-
Postow, L.1
Ghenoiu, C.2
Woo, E.M.3
Krutchinsky, A.N.4
Chait, B.T.5
Funabiki, H.6
-
74
-
-
19944388882
-
Proteasome involvement in the repair of DNA double-strand breaks
-
Krogan NJ, Lam MH, Fillingham J, Keogh MC, Gebbia M, Li J et al. Proteasome involvement in the repair of DNA double-strand breaks. Mol Cell 2004; 16: 1027-1034.
-
(2004)
Mol Cell
, vol.16
, pp. 1027-1034
-
-
Krogan, N.J.1
Lam, M.H.2
Fillingham, J.3
Keogh, M.C.4
Gebbia, M.5
Li, J.6
-
75
-
-
0031105037
-
Structural and functional properties of proteasome activator PA28
-
Kuehn L, Dahlmann B. Structural and functional properties of proteasome activator PA28. Mol Biol Rep 1997; 24: 89-93.
-
(1997)
Mol Biol Rep
, vol.24
, pp. 89-93
-
-
Kuehn, L.1
Dahlmann, B.2
-
76
-
-
0036646488
-
PA200, a nuclear proteasome activator involved in DNA repair
-
Ustrell V, Hoffman L, Pratt G, Rechsteiner M. PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 2002; 21: 3516-3525.
-
(2002)
EMBO J
, vol.21
, pp. 3516-3525
-
-
Ustrell, V.1
Hoffman, L.2
Pratt, G.3
Rechsteiner, M.4
-
77
-
-
55849123303
-
Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability
-
Blickwedehl J, Agarwal M, Seong C, Pandita RK, Melendy T, Sung P et al. Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability. Proc Natl Acad Sci USA 2008; 105: 16165-16170.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16165-16170
-
-
Blickwedehl, J.1
Agarwal, M.2
Seong, C.3
Pandita, R.K.4
Melendy, T.5
Sung, P.6
-
78
-
-
34447549100
-
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation
-
Blickwedehl J, McEvoy S, Wong I, Kousis P, Clements J, Elliott R et al. Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation. Radiat Res 2007; 167: 663-674.
-
(2007)
Radiat Res
, vol.167
, pp. 663-674
-
-
Blickwedehl, J.1
McEvoy, S.2
Wong, I.3
Kousis, P.4
Clements, J.5
Elliott, R.6
-
79
-
-
84055184842
-
Involvement of the nuclear proteasome activator PA28gamma in the cellular response to DNA double-strand breaks
-
Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z et al. Involvement of the nuclear proteasome activator PA28gamma in the cellular response to DNA double-strand breaks. Cell Cycle 2011; 10: 24.
-
(2011)
Cell Cycle
, vol.10
, pp. 24
-
-
Levy-Barda, A.1
Lerenthal, Y.2
Davis, A.J.3
Chung, Y.M.4
Essers, J.5
Shao, Z.6
-
80
-
-
84863299183
-
S5a/Rpn10, a UIM-protein, as a universal substrate for ubiquitination
-
Kim HT, Goldberg AL. S5a/Rpn10, a UIM-protein, as a universal substrate for ubiquitination. Methods Mol Biol 2012; 832: 653-660.
-
(2012)
Methods Mol Biol
, vol.832
, pp. 653-660
-
-
Kim, H.T.1
Goldberg, A.L.2
-
81
-
-
67650427174
-
S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains
-
Kim HT, Kim KP, Uchiki T, Gygi SP, Goldberg AL. S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains. EMBO J 2009; 28: 1867-1877.
-
(2009)
EMBO J
, vol.28
, pp. 1867-1877
-
-
Kim, H.T.1
Kim, K.P.2
Uchiki, T.3
Gygi, S.P.4
Goldberg, A.L.5
-
82
-
-
80053583606
-
A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction
-
Raman M, Havens CG, Walter JC, Harper JW. A genome-wide screen identifies p97 as an essential regulator of DNA damage-dependent CDT1 destruction. Mol Cell 2011; 44: 72-84.
-
(2011)
Mol Cell
, vol.44
, pp. 72-84
-
-
Raman, M.1
Havens, C.G.2
Walter, J.C.3
Harper, J.W.4
-
83
-
-
80053606383
-
CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication
-
Franz A, Orth M, Pirson PA, Sonneville R, Blow JJ, Gartner A et al. CDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication. Mol Cell 2011; 44: 85-96.
-
(2011)
Mol Cell
, vol.44
, pp. 85-96
-
-
Franz, A.1
Orth, M.2
Pirson, P.A.3
Sonneville, R.4
Blow, J.J.5
Gartner, A.6
-
84
-
-
84856474838
-
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
-
Meyer H, Bug M, Bremer S. Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat Cell Biol 2012; 14: 117-123.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 117-123
-
-
Meyer, H.1
Bug, M.2
Bremer, S.3
-
85
-
-
84862777619
-
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
-
Feng L, Chen J. The E3 ligase RNF8 regulates KU80 removal and NHEJ repair. Nat Struct Mol Biol 2012; 19: 201-206.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 201-206
-
-
Feng, L.1
Chen, J.2
-
86
-
-
80052568653
-
SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitinmediated proteasomal degradation
-
Tan MK, Lim HJ, Harper JW. SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitinmediated proteasomal degradation. Mol Cell Biol 2011; 31: 3687-3699.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3687-3699
-
-
Tan, M.K.1
Lim, H.J.2
Harper, J.W.3
-
87
-
-
84865024389
-
K48-linked ubiquitination and protein degradation regulate 53BP1 recruitment at DNA damage sites
-
Mallette FA, Richard S. K48-linked ubiquitination and protein degradation regulate 53BP1 recruitment at DNA damage sites. Cell Res 2012; 22: 1221-1223.
-
(2012)
Cell Res
, vol.22
, pp. 1221-1223
-
-
Mallette, F.A.1
Richard, S.2
-
88
-
-
5344269437
-
Sculpting the proteome with AAA(\+) proteases and disassembly machines
-
Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA et al. Sculpting the proteome with AAA(\+) proteases and disassembly machines. Cell 2004; 119: 9-18.
-
(2004)
Cell
, vol.119
, pp. 9-18
-
-
Sauer, R.T.1
Bolon, D.N.2
Burton, B.M.3
Burton, R.E.4
Flynn, J.M.5
Grant, R.A.6
-
89
-
-
11844263929
-
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting
-
Richly H, Rape M, Braun S, Rumpf S, Hoege C, Jentsch S. A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting. Cell 2005; 120: 73-84.
-
(2005)
Cell
, vol.120
, pp. 73-84
-
-
Richly, H.1
Rape, M.2
Braun, S.3
Rumpf, S.4
Hoege, C.5
Jentsch, S.6
-
90
-
-
73349115264
-
A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex
-
Wilcox AJ, Laney JD. A ubiquitin-selective AAA-ATPase mediates transcriptional switching by remodelling a repressor-promoter DNA complex. Nat Cell Biol 2009; 11: 1481-1486.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1481-1486
-
-
Wilcox, A.J.1
Laney, J.D.2
-
91
-
-
30744451400
-
Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone
-
Rumpf S, Jentsch S. Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol Cell 2006; 21: 261-269.
-
(2006)
Mol Cell
, vol.21
, pp. 261-269
-
-
Rumpf, S.1
Jentsch, S.2
-
92
-
-
78650733298
-
Cdc48/p97 mediates UVdependent turnover of RNA Pol II
-
Verma R, Oania R, Fang R, Smith GT, Deshaies RJ. Cdc48/p97 mediates UVdependent turnover of RNA Pol II. Mol Cell 2011; 41: 82-92.
-
(2011)
Mol Cell
, vol.41
, pp. 82-92
-
-
Verma, R.1
Oania, R.2
Fang, R.3
Smith, G.T.4
Deshaies, R.J.5
-
93
-
-
79953687692
-
Enzymatic blockade of the ubiquitin-proteasome pathway
-
Ernst R, Claessen JH, Mueller B, Sanyal S, Spooner E, van der Veen AG et al. Enzymatic blockade of the ubiquitin-proteasome pathway. PLoS Biol 2011; 8: e1000605.
-
(2011)
PLoS Biol
, vol.8
-
-
Ernst, R.1
Claessen, J.H.2
Mueller, B.3
Sanyal, S.4
Spooner, E.5
Van Der Veen, A.G.6
-
94
-
-
24744434431
-
Valosin-containing protein phosphorylation at Ser784 in response to DNA damage
-
Livingstone M, Ruan H, Weiner J, Clauser KR, Strack P, Jin S et al. Valosin-containing protein phosphorylation at Ser784 in response to DNA damage. Cancer Res 2005; 65: 7533-7540.
-
(2005)
Cancer Res
, vol.65
, pp. 7533-7540
-
-
Livingstone, M.1
Ruan, H.2
Weiner, J.3
Clauser, K.R.4
Strack, P.5
Jin, S.6
-
95
-
-
0033855808
-
VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells
-
Zhang H, Wang Q, Kajino K, Greene MI. VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells. DNA Cell Biol 2000; 19: 253-263.
-
(2000)
DNA Cell Biol
, vol.19
, pp. 253-263
-
-
Zhang, H.1
Wang, Q.2
Kajino, K.3
Greene, M.I.4
-
96
-
-
1642353529
-
Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATPdependent fashion
-
Indig FE, Partridge JJ, von Kobbe C, Aladjem MI, Latterich M, Bohr VA. Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATPdependent fashion. J Struct Biol 2004; 146: 251-259.
-
(2004)
J Struct Biol
, vol.146
, pp. 251-259
-
-
Indig, F.E.1
Partridge, J.J.2
Von Kobbe, C.3
Aladjem, M.I.4
Latterich, M.5
Bohr, V.A.6
-
97
-
-
0033959478
-
P97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication
-
Yamada T, Okuhara K, Iwamatsu A, Seo H, Ohta K, Shibata T et al. p97 ATPase, an ATPase involved in membrane fusion, interacts with DNA unwinding factor (DUF) that functions in DNA replication. FEBS Lett 2000; 466: 287-291.
-
(2000)
FEBS Lett
, vol.466
, pp. 287-291
-
-
Yamada, T.1
Okuhara, K.2
Iwamatsu, A.3
Seo, H.4
Ohta, K.5
Shibata, T.6
-
98
-
-
36849095082
-
L3MBTL1 recognition of mono-and dimethylated histones
-
Min J, Allali-Hassani A, Nady N, Qi C, Ouyang H, Liu Y et al. L3MBTL1 recognition of mono-and dimethylated histones. Nat Struct Mol Biol 2007; 14: 1229-1230.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1229-1230
-
-
Min, J.1
Allali-Hassani, A.2
Nady, N.3
Qi, C.4
Ouyang, H.5
Liu, Y.6
-
99
-
-
82955164827
-
Differential regulation of RNF8-mediated Lys48-and Lys63-based poly-ubiquitylation
-
Lok GT, Sy SM, Dong SS, Ching YP, Tsao SW, Thomson TM et al. Differential regulation of RNF8-mediated Lys48-and Lys63-based poly-ubiquitylation. Nucleic Acids Res 2011; 40: 196-205.
-
(2011)
Nucleic Acids Res
, vol.40
, pp. 196-205
-
-
Lok, G.T.1
Sy, S.M.2
Dong, S.S.3
Ching, Y.P.4
Tsao, S.W.5
Thomson, T.M.6
-
100
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova N, Chen YC, Spector DL, de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008; 456: 524-528.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
Chen, Y.C.2
Spector, D.L.3
De Lange, T.4
-
101
-
-
79955502009
-
Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1
-
Bothmer A, Robbiani DF, Di Virgilio M, Bunting SF, Klein IA, Feldhahn N et al. Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1. Mol Cell 2011; 42: 319-329.
-
(2011)
Mol Cell
, vol.42
, pp. 319-329
-
-
Bothmer, A.1
Robbiani, D.F.2
Di Virgilio, M.3
Bunting, S.F.4
Klein, I.A.5
Feldhahn, N.6
-
102
-
-
84864076551
-
Rap80 Recruitment to DNA double strand breaks requires binding to both sumo-and ubiquitin-conjugates
-
Hu X, Paul A, Wang B. Rap80 Recruitment to DNA double strand breaks requires binding to both sumo-and ubiquitin-conjugates. J Biol Chem 2012; 287: 25510-25519.
-
(2012)
J Biol Chem
, vol.287
, pp. 25510-25519
-
-
Hu, X.1
Paul, A.2
Wang, B.3
-
103
-
-
84870760201
-
RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage
-
Guzzo CM, Berndsen CE, Zhu J, Gupta V, Datta A, Greenberg RA et al. RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. Sci Signal 2012; 5: 88.
-
(2012)
Sci Signal
, vol.5
, pp. 88
-
-
Guzzo, C.M.1
Berndsen, C.E.2
Zhu, J.3
Gupta, V.4
Datta, A.5
Greenberg, R.A.6
-
104
-
-
63049138322
-
NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control
-
Wang B, Hurov K, Hofmann K, Elledge SJ. NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. Genes Dev 2009; 23: 729-739.
-
(2009)
Genes Dev
, vol.23
, pp. 729-739
-
-
Wang, B.1
Hurov, K.2
Hofmann, K.3
Elledge, S.J.4
-
105
-
-
70349982566
-
A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: Identification of specific differences between BRCA1 and 53BP1 at DNA damage-induced foci
-
Mok MT, Henderson BR. A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: identification of specific differences between BRCA1 and 53BP1 at DNA damage-induced foci. Cell Signal 2010; 22: 47-56.
-
(2010)
Cell Signal
, vol.22
, pp. 47-56
-
-
Mok, M.T.1
Henderson, B.R.2
-
106
-
-
84865386136
-
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair
-
Chapman JR, Sossick AJ, Boulton SJ, Jackson SP. BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. J Cell Sci 2012; 125(Pt 15): 3529-3534.
-
(2012)
J Cell Sci
, vol.125
, Issue.PART. 15
, pp. 3529-3534
-
-
Chapman, J.R.1
Sossick, A.J.2
Boulton, S.J.3
Jackson, S.P.4
-
107
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
-
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 2010; 17: 688-695.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
Van Der Gulden, H.6
-
108
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting SF, Callen E, Wong N, Chen HT, Polato F, Gunn A et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010; 141: 243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
Gunn, A.6
-
109
-
-
68949221567
-
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency
-
Cao L, Xu X, Bunting SF, Liu J, Wang RH, Cao LL et al. A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. Mol Cell 2009; 35: 534-541.
-
(2009)
Mol Cell
, vol.35
, pp. 534-541
-
-
Cao, L.1
Xu, X.2
Bunting, S.F.3
Liu, J.4
Wang, R.H.5
Cao, L.L.6
-
110
-
-
84865232294
-
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
-
Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grofte M et al. TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell 2012; 150: 697-709.
-
(2012)
Cell
, vol.150
, pp. 697-709
-
-
Gudjonsson, T.1
Altmeyer, M.2
Savic, V.3
Toledo, L.4
Dinant, C.5
Grofte, M.6
-
111
-
-
84857411692
-
Identification of mammalian protein quality control factors by high-throughput cellular imaging
-
Pegoraro G, Voss TC, Martin SE, Tuzmen P, Guha R, Misteli T. Identification of mammalian protein quality control factors by high-throughput cellular imaging. PLoS ONE 2012; 7: e31684.
-
(2012)
PLoS ONE
, vol.7
-
-
Pegoraro, G.1
Voss, T.C.2
Martin, S.E.3
Tuzmen, P.4
Guha, R.5
Misteli, T.6
-
112
-
-
78649433314
-
Depletion of DSS1 protein disables homologous recombinational repair in human cells
-
Kristensen CN, Bystol KM, Li B, Serrano L, Brenneman MA. Depletion of DSS1 protein disables homologous recombinational repair in human cells. Mutat Res 2010; 694: 60-64.
-
(2010)
Mutat Res
, vol.694
, pp. 60-64
-
-
Kristensen, C.N.1
Bystol, K.M.2
Li, B.3
Serrano, L.4
Brenneman, M.A.5
-
113
-
-
34147195807
-
Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair
-
Zhou Q, Kojic M, Cao Z, Lisby M, Mazloum NA, Holloman WK. Dss1 interaction with Brh2 as a regulatory mechanism for recombinational repair. Mol Cell Biol 2007; 27: 2512-2526.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2512-2526
-
-
Zhou, Q.1
Kojic, M.2
Cao, Z.3
Lisby, M.4
Mazloum, N.A.5
Holloman, W.K.6
-
114
-
-
15044340651
-
Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis
-
Kojic M, Zhou Q, Lisby M, Holloman WK. Brh2-Dss1 interplay enables properly controlled recombination in Ustilago maydis. Mol Cell Biol 2005; 25: 2547-2557.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2547-2557
-
-
Kojic, M.1
Zhou, Q.2
Lisby, M.3
Holloman, W.K.4
-
115
-
-
77957804215
-
Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA
-
Liu J, Doty T, Gibson B, Heyer WD. Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nat Struct Mol Biol 2010; 17: 1260-1262
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1260-1262
-
-
Liu, J.1
Doty, T.2
Gibson, B.3
Heyer, W.D.4
-
116
-
-
69049099939
-
Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents
-
Takeshita T, Wu W, Koike A, Fukuda M, Ohta T. Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents. Cancer Chemotherapy Pharmacol 2009; 64: 1039-1046.
-
(2009)
Cancer Chemotherapy Pharmacol
, vol.64
, pp. 1039-1046
-
-
Takeshita, T.1
Wu, W.2
Koike, A.3
Fukuda, M.4
Ohta, T.5
-
117
-
-
83455195500
-
Bortezomib-induced 'BRCAness' sensitizes multiple myeloma cells to PARP inhibitors
-
Neri P, Ren L, Gratton K, Stebner E, Johnson J, Klimowicz A et al. Bortezomib-induced 'BRCAness' sensitizes multiple myeloma cells to PARP inhibitors. Blood 2011; 118: 6368-6379.
-
(2011)
Blood
, vol.118
, pp. 6368-6379
-
-
Neri, P.1
Ren, L.2
Gratton, K.3
Stebner, E.4
Johnson, J.5
Klimowicz, A.6
-
118
-
-
50449086728
-
Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
-
San Miguel JF, Schlag R, Khuageva NK, Dimopoulos MA, Shpilberg O, Kropff M et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008; 359: 906-917.
-
(2008)
N Engl J Med
, vol.359
, pp. 906-917
-
-
San Miguel, J.F.1
Schlag, R.2
Khuageva, N.K.3
Dimopoulos, M.A.4
Shpilberg, O.5
Kropff, M.6
-
119
-
-
22144466584
-
The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells
-
Chen Q, Van der Sluis PC, Boulware D, Hazlehurst LA, Dalton WS. The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells. Blood 2005; 106: 698-705.
-
(2005)
Blood
, vol.106
, pp. 698-705
-
-
Chen, Q.1
Van Der Sluis, P.C.2
Boulware, D.3
Hazlehurst, L.A.4
Dalton, W.S.5
-
120
-
-
84862908084
-
A phase i study evaluating ibritumomab tiuxetan (Zevalin(R)) in combination with bortezomib (Velcade(R)) in relapsed/refractory mantle cell and low grade B-cell non-Hodgkin lymphoma
-
Beaven AW, Shea TC, Moore DT, Feldman T, Ivanova A, Ferraro M et al. A phase I study evaluating ibritumomab tiuxetan (Zevalin(R)) in combination with bortezomib (Velcade(R)) in relapsed/refractory mantle cell and low grade B-cell non-Hodgkin lymphoma. Leukemia Lymphoma 2012; 53: 254-258.
-
(2012)
Leukemia Lymphoma
, vol.53
, pp. 254-258
-
-
Beaven, A.W.1
Shea, T.C.2
Moore, D.T.3
Feldman, T.4
Ivanova, A.5
Ferraro, M.6
-
121
-
-
84864568543
-
Proteasome inhibitors in multiple myeloma: 10 years later
-
Moreau P, Richardson PG, Cavo M, Orlowski RZ, San Miguel JF, Palumbo A et al. Proteasome inhibitors in multiple myeloma: 10 years later. Blood 2012; 120: 947-959.
-
(2012)
Blood
, vol.120
, pp. 947-959
-
-
Moreau, P.1
Richardson, P.G.2
Cavo, M.3
Orlowski, R.Z.4
San Miguel, J.F.5
Palumbo, A.6
-
122
-
-
84858683642
-
Targeting the ubiquitin-proteasome pathway with inorganic compounds to fight cancer: A challenge for the future
-
Dalla Via L, Nardon C, Fregona D. Targeting the ubiquitin-proteasome pathway with inorganic compounds to fight cancer: a challenge for the future. Future Med Chem 2012; 4: 525-543.
-
(2012)
Future Med Chem
, vol.4
, pp. 525-543
-
-
Dalla Via, L.1
Nardon, C.2
Fregona, D.3
-
123
-
-
84859395758
-
Advances in the treatment of relapsed or refractory Hodgkin's lymphoma
-
Ramchandren R. Advances in the treatment of relapsed or refractory Hodgkin's lymphoma. Oncol 2012; 17: 367-376.
-
(2012)
Oncol
, vol.17
, pp. 367-376
-
-
Ramchandren, R.1
-
125
-
-
84864448811
-
Proteasome deubiquitinases as novel targets for cancer therapy
-
D'Arcy P, Linder S. Proteasome deubiquitinases as novel targets for cancer therapy. Int J Biochem Cell Biol 2012; 44: 1729-1738.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1729-1738
-
-
D'Arcy, P.1
Linder, S.2
-
126
-
-
79951688311
-
Targeting malignancies with disulfiram (Antabuse): Multidrug resistance, angiogenesis, and proteasome
-
Cvek B. Targeting malignancies with disulfiram (Antabuse): multidrug resistance, angiogenesis, and proteasome. Curr Cancer Drug Targets 2011; 11: 332-337.
-
(2011)
Curr Cancer Drug Targets
, vol.11
, pp. 332-337
-
-
Cvek, B.1
-
127
-
-
33846849171
-
The JAMM motif of human deubiquitinase Poh1 is essential for cell viability
-
Gallery M, Blank JL, Lin Y, Gutierrez JA, Pulido JC, Rappoli D et al. The JAMM motif of human deubiquitinase Poh1 is essential for cell viability. Mol Cancer Ther 2007; 6: 262-268.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 262-268
-
-
Gallery, M.1
Blank, J.L.2
Lin, Y.3
Gutierrez, J.A.4
Pulido, J.C.5
Rappoli, D.6
-
128
-
-
84857134729
-
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
-
Lasker K, Forster F, Bohn S, Walzthoeni T, Villa E, Unverdorben P et al. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci USA 2012; 109: 1380-1387.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1380-1387
-
-
Lasker, K.1
Forster, F.2
Bohn, S.3
Walzthoeni, T.4
Villa, E.5
Unverdorben, P.6
-
129
-
-
84856976866
-
Complete subunit architecture of the proteasome regulatory particle
-
Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Complete subunit architecture of the proteasome regulatory particle. Nature 2012; 482: 186-191.
-
(2012)
Nature
, vol.482
, pp. 186-191
-
-
Lander, G.C.1
Estrin, E.2
Matyskiela, M.E.3
Bashore, C.4
Nogales, E.5
Martin, A.6
-
130
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 2005; 123: 773-786.
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
-
131
-
-
0037131243
-
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome
-
Verma R, Aravind L, Oania R, McDonald WH, Yates 3rd JR, Koonin EV et al. Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science 2002; 298: 611-615.
-
(2002)
Science
, vol.298
, pp. 611-615
-
-
Verma, R.1
Aravind, L.2
Oania, R.3
McDonald, W.H.4
Yates III, J.R.5
Koonin, E.V.6
-
132
-
-
0037179694
-
A cryptic protease couples deubiquitination and degradation by the proteasome
-
Yao T, Cohen RE. A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 2002; 419: 403-407.
-
(2002)
Nature
, vol.419
, pp. 403-407
-
-
Yao, T.1
Cohen, R.E.2
-
133
-
-
33744947551
-
The 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localization
-
Nabhan JF, Ribeiro P. The 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localization. J Biol Chem 2006; 281: 16099-16107.
-
(2006)
J Biol Chem
, vol.281
, pp. 16099-16107
-
-
Nabhan, J.F.1
Ribeiro, P.2
-
134
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-[kappa] B signalling
-
Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-[kappa]B signalling. Nature 2004; 430: 694-699.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
-
135
-
-
0345099501
-
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
-
Burnett B, Li F, Pittman RN. The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity. Human Mol Genet 2003; 12: 3195-3205.
-
(2003)
Human Mol Genet
, vol.12
, pp. 3195-3205
-
-
Burnett, B.1
Li, F.2
Pittman, R.N.3
-
136
-
-
0242693202
-
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
-
Scheel H, Tomiuk S, Hofmann K. Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics. Human Mol Genet 2003; 12: 2845-2852.
-
(2003)
Human Mol Genet
, vol.12
, pp. 2845-2852
-
-
Scheel, H.1
Tomiuk, S.2
Hofmann, K.3
-
137
-
-
0037131567
-
The UCH-L1 gene encodes two opposing enzymatic activities that affect a-synuclein degradation and parkinson's disease susceptibility
-
Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury Jr PT. The UCH-L1 gene encodes two opposing enzymatic activities that affect a-synuclein degradation and parkinson's disease susceptibility. Cell 2002; 111: 209-218.
-
(2002)
Cell
, vol.111
, pp. 209-218
-
-
Liu, Y.1
Fallon, L.2
Lashuel, H.A.3
Liu, Z.4
Lansbury Jr., P.T.5
-
138
-
-
0031038169
-
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome
-
Lam YA, Xu W, DeMartino GN, Cohen RE. Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome. Nature 1997; 385: 737-740.
-
(1997)
Nature
, vol.385
, pp. 737-740
-
-
Lam, Y.A.1
Xu, W.2
Demartino, G.N.3
Cohen, R.E.4
-
139
-
-
70449704010
-
Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain
-
Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J et al. Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain. Biochem Biophys Res Commun 2009; 390: 855-860.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 855-860
-
-
Nishio, K.1
Kim, S.W.2
Kawai, K.3
Mizushima, T.4
Yamane, T.5
Hamazaki, J.6
-
140
-
-
4344717012
-
BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage
-
Schoenfeld AR, Apgar S, Dolios G, Wang R, Aaronson SA. BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. Mol Cell Biol 2004; 24: 7444-7455.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7444-7455
-
-
Schoenfeld, A.R.1
Apgar, S.2
Dolios, G.3
Wang, R.4
Aaronson, S.A.5
-
141
-
-
0042467554
-
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-[kappa] B
-
Brummelkamp TR, Nijman SMB, Dirac AMG, Bernards R. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-[kappa]B. Nature 2003; 424: 797-801.
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.B.2
Dirac, A.M.G.3
Bernards, R.4
-
142
-
-
0041967054
-
The tumour suppressor CYLD negatively regulates NF-[kappa] B signalling by deubiquitination
-
Kovalenko A, Chable-Bessia C, Cantarella G, Israel A, Wallach D, Courtois G. The tumour suppressor CYLD negatively regulates NF-[kappa]B signalling by deubiquitination. Nature 2003; 424: 801-805.
-
(2003)
Nature
, vol.424
, pp. 801-805
-
-
Kovalenko, A.1
Chable-Bessia, C.2
Cantarella, G.3
Israel, A.4
Wallach, D.5
Courtois, G.6
-
143
-
-
0042467558
-
CYLD is a deubiquitinating enzyme that negatively regulates NF-[kappa] B activation by TNFR family members
-
Trompouki E, Hatzivassiliou E, Tsichritzis T, Farmer H, Ashworth A, Mosialos G. CYLD is a deubiquitinating enzyme that negatively regulates NF-[kappa]B activation by TNFR family members. Nature 2003; 424: 793-796.
-
(2003)
Nature
, vol.424
, pp. 793-796
-
-
Trompouki, E.1
Hatzivassiliou, E.2
Tsichritzis, T.3
Farmer, H.4
Ashworth, A.5
Mosialos, G.6
-
144
-
-
13244291457
-
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
-
Nijman SMB, Huang TT, Dirac AMG, Brummelkamp TR, Kerkhoven RM, D'Andrea AD et al. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell 2005; 17: 331-339.
-
(2005)
Mol Cell
, vol.17
, pp. 331-339
-
-
Smb, N.1
Huang, T.T.2
Amg, D.3
Brummelkamp, T.R.4
Kerkhoven, R.M.5
D'Andrea, A.D.6
-
145
-
-
1942470483
-
Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analoguesw,z
-
Russell NS, Wilkinson KD. Identification of a novel 29-linked polyubiquitin binding protein, Ufd3, using polyubiquitin chain analoguesw,z. Biochemistry 2004; 43: 4844-4854.
-
(2004)
Biochemistry
, vol.43
, pp. 4844-4854
-
-
Russell, N.S.1
Wilkinson, K.D.2
|