BRCA1-associated exclusion of 53BP1 from DNA: Damage sites underlies temporal control of DNA repair

Journal of Cell Science

Volumn 125, Issue 15, 2012, Pages 3529-3534

  Chapman, J Ross ^a,b   Sossick, Alex J ^a   Boulton, Simon J ^b   Jackson, Stephen P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

H2AX; 53bp1; Brca1; DNA damage; DNA double strand breaks; IRIF; Structured illumination; Super resolution microscopy

Indexed keywords

53BP1 PROTEIN; BRCA1 PROTEIN; HISTONE H2AX GAMMA; NUCLEAR PROTEIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG;

ARTICLE; CELL AGGREGATION; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENOMIC INSTABILITY; HELA CELL; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IONISING RADIATION INDUCED FOCUS; PRIORITY JOURNAL; PROTEIN ANALYSIS;

BRCA1 PROTEIN; CELL CULTURE TECHNIQUES; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; TRANSFECTION;

EID: 84865386136     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.105353     Document Type: Article

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