BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage

Molecular and Cellular Biology

Volumn 24, Issue 17, 2004, Pages 7444-7455

  Schoenfeld, Alan R ^a   Apgar, Sarah ^a   Dolios, Georgia ^a   Wang, Rong ^a   Aaronson, Stuart A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; GENE PRODUCT; MITOMYCIN C; MUTANT PROTEIN; PROTEASOME; PROTEIN USP11; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DRUG SENSITIVITY; EMBRYO; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; BRCA2 PROTEIN; CELL LINE; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; DNA DAMAGE; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; MITOMYCIN; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SEQUENCE ALIGNMENT; THIOLESTER HYDROLASES; UBIQUITIN; UP-REGULATION;

EID: 4344717012     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.17.7444-7455.2004     Document Type: Article

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