메뉴 건너뛰기




Volumn 67, Issue 15, 2007, Pages 7395-7405

Proteasome function is required for DNA damage response and fanconi anemia pathway activation

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; BRCA1 PROTEIN; BRCA2 PROTEIN; CISPLATIN; DNA; FANCONI ANEMIA GROUP D2 PROTEIN; LACTACYSTIN; NIBRIN; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN SUBUNIT; RAD51 PROTEIN;

EID: 34547628200     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-1015     Document Type: Article
Times cited : (188)

References (50)
  • 1
    • 1542344435 scopus 로고    scopus 로고
    • Proteasomes and their kin: Proteases in the machine age
    • Pickart CM, Cohen RE. Proteasomes and their kin: proteases in the machine age. Nat Rev Mol Cell Biol 2004;5:177-87.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 177-187
    • Pickart, C.M.1    Cohen, R.E.2
  • 3
    • 18244406798 scopus 로고    scopus 로고
    • Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib
    • Berkers CR, Verdoes M, Lichtman E, et al. Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib. Nat Methods 2005;2:357-62.
    • (2005) Nat Methods , vol.2 , pp. 357-362
    • Berkers, C.R.1    Verdoes, M.2    Lichtman, E.3
  • 4
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer 2004;4:349-60.
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 6
    • 0034237661 scopus 로고    scopus 로고
    • Apoptosis and radiosensitization of hodgkin cells by proteasome inhibition
    • Pajonk F, Pajonk K, McBride WH. Apoptosis and radiosensitization of hodgkin cells by proteasome inhibition. Int J Radiat Oncol Biol Phys 2000;47:1025-32.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 1025-1032
    • Pajonk, F.1    Pajonk, K.2    McBride, W.H.3
  • 7
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • Mitsiades N, Mitsiades CS, Richardson PG, et al. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 2003;101:2377-80.
    • (2003) Blood , vol.101 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3
  • 8
    • 0035487184 scopus 로고    scopus 로고
    • Effect of the proteasome inhibitor ALLnL on cisplatin sensitivity in human ovarian tumor cells
    • Yunmbam MK, Li QQ, Mimnaugh EG, et al. Effect of the proteasome inhibitor ALLnL on cisplatin sensitivity in human ovarian tumor cells. Int J Oncol 2001;19:741-8.
    • (2001) Int J Oncol , vol.19 , pp. 741-748
    • Yunmbam, M.K.1    Li, Q.Q.2    Mimnaugh, E.G.3
  • 9
    • 33644916110 scopus 로고    scopus 로고
    • Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma
    • Berenson JR, Yang HH, Sadler K, et al. Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma. J Clin Oncol 2006;24:937-44.
    • (2006) J Clin Oncol , vol.24 , pp. 937-944
    • Berenson, J.R.1    Yang, H.H.2    Sadler, K.3
  • 10
  • 11
    • 33744481750 scopus 로고    scopus 로고
    • Molecular pathogenesis of Fanconi anemia: Recent progress
    • Taniguchi T, D'Andrea AD. Molecular pathogenesis of Fanconi anemia: recent progress. Blood 2006;107:4223-33.
    • (2006) Blood , vol.107 , pp. 4223-4233
    • Taniguchi, T.1    D'Andrea, A.D.2
  • 12
    • 0035105291 scopus 로고    scopus 로고
    • Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
    • Garcia-Higuera I, Taniguchi T, Ganesan S, et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 2001;7:249-62.
    • (2001) Mol Cell , vol.7 , pp. 249-262
    • Garcia-Higuera, I.1    Taniguchi, T.2    Ganesan, S.3
  • 14
    • 4043133287 scopus 로고    scopus 로고
    • ATR couples FANCD2 monoubiquitination to the DNA-damage response
    • Andreassen PR, D'Andrea AD, Taniguchi T. ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev 2004;18:1958-63.
    • (2004) Genes Dev , vol.18 , pp. 1958-1963
    • Andreassen, P.R.1    D'Andrea, A.D.2    Taniguchi, T.3
  • 15
    • 0141484612 scopus 로고    scopus 로고
    • A novel ubiquitin ligase is deficient in Fanconi anemia
    • Meetei AR, de Winter JP, Medhurst AL, et al. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 2003;35:165-70.
    • (2003) Nat Genet , vol.35 , pp. 165-170
    • Meetei, A.R.1    de Winter, J.P.2    Medhurst, A.L.3
  • 16
    • 33746957852 scopus 로고    scopus 로고
    • UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation
    • Machida YJ, Machida Y, Chen Y, et al. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell 2006;23:589-96.
    • (2006) Mol Cell , vol.23 , pp. 589-596
    • Machida, Y.J.1    Machida, Y.2    Chen, Y.3
  • 17
    • 13244291457 scopus 로고    scopus 로고
    • The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
    • Nijman SM, Huang TT, Dirac AM, et al. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell 2005;17:331-9.
    • (2005) Mol Cell , vol.17 , pp. 331-339
    • Nijman, S.M.1    Huang, T.T.2    Dirac, A.M.3
  • 18
    • 19944388882 scopus 로고    scopus 로고
    • Proteasome involvement in the repair of DNA double-strand breaks
    • Krogan NJ, Lam MH, Fillingham J, et al. Proteasome involvement in the repair of DNA double-strand breaks. Mol Cell 2004;16:1027-34.
    • (2004) Mol Cell , vol.16 , pp. 1027-1034
    • Krogan, N.J.1    Lam, M.H.2    Fillingham, J.3
  • 19
    • 0033026065 scopus 로고    scopus 로고
    • Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals
    • Marston NJ, Richards WJ, Hughes D, Bertwistle D, Marshall CJ, Ashworth A. Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals. Mol Cell Biol 1999;19:4633-42.
    • (1999) Mol Cell Biol , vol.19 , pp. 4633-4642
    • Marston, N.J.1    Richards, W.J.2    Hughes, D.3    Bertwistle, D.4    Marshall, C.J.5    Ashworth, A.6
  • 21
    • 8844243320 scopus 로고    scopus 로고
    • DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells
    • Gudmundsdottir K, Lord CJ, Witt E, Tutt AN, Ashworth A. DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells. EMBO Rep 2004;5:989-93.
    • (2004) EMBO Rep , vol.5 , pp. 989-993
    • Gudmundsdottir, K.1    Lord, C.J.2    Witt, E.3    Tutt, A.N.4    Ashworth, A.5
  • 22
    • 0038075462 scopus 로고    scopus 로고
    • Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
    • Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003;9:568-74.
    • (2003) Nat Med , vol.9 , pp. 568-574
    • Taniguchi, T.1    Tischkowitz, M.2    Ameziane, N.3
  • 23
    • 0035947372 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system by protein aggregation
    • Bence NF, Sampat RM, Kopito RR. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 2001;292:1552-5.
    • (2001) Science , vol.292 , pp. 1552-1555
    • Bence, N.F.1    Sampat, R.M.2    Kopito, R.R.3
  • 24
    • 33645708319 scopus 로고    scopus 로고
    • Regulation of monoubiquitinated PCNA by DUB autocleavage
    • Huang TT, Nijman SM, Mirchandani KD, et al. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat Cell Biol 2006;8:339-47.
    • (2006) Nat Cell Biol , vol.8 , pp. 339-347
    • Huang, T.T.1    Nijman, S.M.2    Mirchandani, K.D.3
  • 25
    • 33646196532 scopus 로고    scopus 로고
    • Regulation of DNA repair by ubiquitylation
    • Huang TT, D'Andrea AD. Regulation of DNA repair by ubiquitylation. Nat Rev Mol Cell Biol 2006;7:323-34.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 323-334
    • Huang, T.T.1    D'Andrea, A.D.2
  • 26
    • 33645731673 scopus 로고    scopus 로고
    • A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling
    • Dantuma NP, Groothuis TA, Salomons FA, Neefjes J. A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling. J Cell Biol 2006;173:19-26.
    • (2006) J Cell Biol , vol.173 , pp. 19-26
    • Dantuma, N.P.1    Groothuis, T.A.2    Salomons, F.A.3    Neefjes, J.4
  • 27
    • 0035903538 scopus 로고    scopus 로고
    • A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14
    • Borodovsky A, Kessler BM, Casagrande R, Overkleeft HS, Wilkinson KD, Ploegh HL. A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14. EMBO J 2001;20:5187-96.
    • (2001) EMBO J , vol.20 , pp. 5187-5196
    • Borodovsky, A.1    Kessler, B.M.2    Casagrande, R.3    Overkleeft, H.S.4    Wilkinson, K.D.5    Ploegh, H.L.6
  • 28
    • 0141788633 scopus 로고    scopus 로고
    • Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport
    • Reuter TY, Medhurst AL, Waisfisz Q, et al. Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. Exp Cell Res 2003;289:211-21.
    • (2003) Exp Cell Res , vol.289 , pp. 211-221
    • Reuter, T.Y.1    Medhurst, A.L.2    Waisfisz, Q.3
  • 29
    • 0034659782 scopus 로고    scopus 로고
    • Posttranscriptional cell cycle-dependent regulation of human FANCC expression
    • Heinrich MC, Silvey KV, Stone S, et al. Posttranscriptional cell cycle-dependent regulation of human FANCC expression. Blood 2000;95:3970-7.
    • (2000) Blood , vol.95 , pp. 3970-3977
    • Heinrich, M.C.1    Silvey, K.V.2    Stone, S.3
  • 30
    • 17644432403 scopus 로고    scopus 로고
    • Chk1 is an essential kinase that is regulated by Atr and required for the G(2) M DNA damage checkpoint
    • Liu Q, Guntuku S, Cui XS, et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2) M DNA damage checkpoint. Genes Dev 2000;14:1448-59.
    • (2000) Genes Dev , vol.14 , pp. 1448-1459
    • Liu, Q.1    Guntuku, S.2    Cui, X.S.3
  • 31
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003;421:499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 32
    • 0034611728 scopus 로고    scopus 로고
    • ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
    • Lim DS, Kim ST, Xu B, et al. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature 2000;404:613-7.
    • (2000) Nature , vol.404 , pp. 613-617
    • Lim, D.S.1    Kim, S.T.2    Xu, B.3
  • 34
    • 33748656748 scopus 로고    scopus 로고
    • Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance
    • Ho GP, Margossian S, Taniguchi T, D'Andrea AD. Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol 2006;26:7005-15.
    • (2006) Mol Cell Biol , vol.26 , pp. 7005-7015
    • Ho, G.P.1    Margossian, S.2    Taniguchi, T.3    D'Andrea, A.D.4
  • 35
    • 3442896884 scopus 로고    scopus 로고
    • Replication protein A phosphorylation and the cellular response to DNA damage
    • Binz SK, Sheehan AM, Wold MS. Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair (Amst) 2004;3:1015-24.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1015-1024
    • Binz, S.K.1    Sheehan, A.M.2    Wold, M.S.3
  • 36
    • 30044432094 scopus 로고    scopus 로고
    • Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis
    • Josse L, Harley ME, Pires IM, Hughes DA. Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis. Biochem J 2006;393:303-9.
    • (2006) Biochem J , vol.393 , pp. 303-309
    • Josse, L.1    Harley, M.E.2    Pires, I.M.3    Hughes, D.A.4
  • 37
    • 4444349390 scopus 로고    scopus 로고
    • Analyzing cell cycle checkpoints after ionizing radiation
    • Xu B, Kastan MB. Analyzing cell cycle checkpoints after ionizing radiation. Methods Mol Biol 2004;281:283-92.
    • (2004) Methods Mol Biol , vol.281 , pp. 283-292
    • Xu, B.1    Kastan, M.B.2
  • 38
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • Lee JH, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005;308:551-4.
    • (2005) Science , vol.308 , pp. 551-554
    • Lee, J.H.1    Paull, T.T.2
  • 39
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003;3:155-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 40
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005;123:1213-26.
    • (2005) Cell , vol.123 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 41
    • 22944462083 scopus 로고    scopus 로고
    • Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
    • Bekker-Jensen S, Lukas C, Melander F, Bartek J, Lukas J. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J Cell Biol 2005;170:201-11.
    • (2005) J Cell Biol , vol.170 , pp. 201-211
    • Bekker-Jensen, S.1    Lukas, C.2    Melander, F.3    Bartek, J.4    Lukas, J.5
  • 42
    • 33845666681 scopus 로고    scopus 로고
    • Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
    • Botuyan MV, Lee J, Ward IM, et al. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006;127:1361-73.
    • (2006) Cell , vol.127 , pp. 1361-1373
    • Botuyan, M.V.1    Lee, J.2    Ward, I.M.3
  • 43
    • 9244252580 scopus 로고    scopus 로고
    • Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
    • Huyen Y, Zgheib O, Ditullio RA, Jr., et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004;432:406-11.
    • (2004) Nature , vol.432 , pp. 406-411
    • Huyen, Y.1    Zgheib, O.2    Ditullio Jr., R.A.3
  • 44
    • 30744465308 scopus 로고    scopus 로고
    • MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
    • Lou Z, Minter-Dykhouse K, Franco S, et al. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol Cell 2006;21:187-200.
    • (2006) Mol Cell , vol.21 , pp. 187-200
    • Lou, Z.1    Minter-Dykhouse, K.2    Franco, S.3
  • 46
    • 19344366752 scopus 로고    scopus 로고
    • Role of saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair
    • Wang X, Haber JE. Role of saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair. PLoS Biol 2004;2:E21.
    • (2004) PLoS Biol , vol.2
    • Wang, X.1    Haber, J.E.2
  • 47
    • 13944266820 scopus 로고    scopus 로고
    • The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
    • Sorensen CS, Hansen LT, Dziegielewski J, et al. The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat Cell Biol 2005;7:195-201.
    • (2005) Nat Cell Biol , vol.7 , pp. 195-201
    • Sorensen, C.S.1    Hansen, L.T.2    Dziegielewski, J.3
  • 48
    • 0034604716 scopus 로고    scopus 로고
    • The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
    • Bhattacharyya A, Ear US, Koller BH, Weichselbaum RR, Bishop DK. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 2000;275:23899-903.
    • (2000) J Biol Chem , vol.275 , pp. 23899-23903
    • Bhattacharyya, A.1    Ear, U.S.2    Koller, B.H.3    Weichselbaum, R.R.4    Bishop, D.K.5
  • 49
    • 0035105999 scopus 로고    scopus 로고
    • Role of BRCA2 in control of the RAD51 recombination and DNA repair protein
    • Davies AA, Masson JY, McIlwraith MJ, et al. Role of BRCA2 in control of the RAD51 recombination and DNA repair protein. Mol Cell 2001;7:273-82.
    • (2001) Mol Cell , vol.7 , pp. 273-282
    • Davies, A.A.1    Masson, J.Y.2    McIlwraith, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.