Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-kB pathways and their target, IEX-1

Blood

Volumn 123, Issue 4, 2014, Pages 509-519

  De Laval, Bérengère ^a,b,c   Pawlikowska, Patrycja ^a,b,c   Barbieri, Daniela ^a,b,c   Besnard Guerin, Corinne ^a,b,c   Cico, Alba ^a,b,c   Kumar, Rajiv ^d   Gaudry, Murielle ^a,b,c   Baud, Véronique ^a,b,c   Porteu, Françoise ^a,b,c  

^a INSTITUT COCHIN   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; THROMBOPOIETIN; ANTINEOPLASTIC AGENT; IEX 1 PROTEIN, MOUSE; IEX-1 PROTEIN, MOUSE; IMMEDIATE EARLY PROTEIN;

ANIMAL CELL; ARTICLE; DNA DAMAGE; DNA END JOINING REPAIR; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; GENE TARGETING; HEMATOPOIETIC STEM CELL; IEX 1 GENE; IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION REGULATION; METABOLISM; PHOSPHORYLATION; STEM CELL; TRANSGENIC MOUSE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTINEOPLASTIC AGENTS; CATALYTIC DOMAIN; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMATOPOIETIC STEM CELLS; IMMEDIATE-EARLY PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELLS; THROMBOPOIETIN;

EID: 84893134358     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-07-515874     Document Type: Article

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