-
1
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature. 2005;434:1144-1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
2
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005;7:387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
3
-
-
30044437118
-
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
-
Lu X, Levine R, Tong W, et al. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci U S A. 2005;102:18962-18967.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18962-18967
-
-
Lu, X.1
Levine, R.2
Tong, W.3
-
4
-
-
0032076542
-
Jak2 is essential for signaling through a variety of cytokine receptors
-
Parganas E, Wang D, Stravopodis D, et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 1998;93:385-395.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravopodis, D.3
-
5
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell. 1998;93:397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Muller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
6
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet. 2005;365:1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
7
-
-
33744490974
-
Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model
-
Wernig G, Mercher T, Okabe R, Levine RL, Lee BH, Gilliland DG. Expression of Jak2V617F causes a polycythemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood. 2006;107:4274-4281.
-
(2006)
Blood
, vol.107
, pp. 4274-4281
-
-
Wernig, G.1
Mercher, T.2
Okabe, R.3
Levine, R.L.4
Lee, B.H.5
Gilliland, D.G.6
-
8
-
-
33744502084
-
Discordant distribution of JAK2V617F mutation in siblings with familial myeloproliferative disorders
-
Pardanani A, Lasho T, McClure R, Lacy M, Tefferi A. Discordant distribution of JAK2V617F mutation in siblings with familial myeloproliferative disorders. Blood. 2006;107:4572-4573.
-
(2006)
Blood
, vol.107
, pp. 4572-4573
-
-
Pardanani, A.1
Lasho, T.2
McClure, R.3
Lacy, M.4
Tefferi, A.5
-
9
-
-
0242493826
-
Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease
-
Kralovics R, Stockton DW, Prchal JT. Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease. Blood. 2003;102:3793-3796.
-
(2003)
Blood
, vol.102
, pp. 3793-3796
-
-
Kralovics, R.1
Stockton, D.W.2
Prchal, J.T.3
-
10
-
-
27244450853
-
The JAK2V617F mutation is acquired secondary to the predisposing alteration in familial polycythaemia vera
-
Cario H, Goerttler PS, Steimle C, Levine RL, Pahl HL. The JAK2V617F mutation is acquired secondary to the predisposing alteration in familial polycythaemia vera. Br J Haematol. 2005;130:800-801.
-
(2005)
Br J Haematol
, vol.130
, pp. 800-801
-
-
Cario, H.1
Goerttler, P.S.2
Steimle, C.3
Levine, R.L.4
Pahl, H.L.5
-
11
-
-
33745623666
-
Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders
-
Bellanne-Chantelot C, Chaumarel I, Labopin M, et al. Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders. Blood. 2006;108:346-352.
-
(2006)
Blood
, vol.108
, pp. 346-352
-
-
Bellanne-Chantelot, C.1
Chaumarel, I.2
Labopin, M.3
-
12
-
-
33645400695
-
X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative et and MMM patients with clonal hematopoiesis
-
Levine RL, Belisle C, Wadleigh M, et al. X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis. Blood. 2006;107:4139-4141.
-
(2006)
Blood
, vol.107
, pp. 4139-4141
-
-
Levine, R.L.1
Belisle, C.2
Wadleigh, M.3
-
13
-
-
33744504164
-
Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders
-
Kiladjian JJ, Elkassar N, Cassinat B, et al. Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders. Leukemia. 2006;20:1181-1183.
-
(2006)
Leukemia
, vol.20
, pp. 1181-1183
-
-
Kiladjian, J.J.1
Elkassar, N.2
Cassinat, B.3
-
14
-
-
33747199312
-
Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders
-
Kralovics R, Teo SS, Li S, et al. Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders. Blood. 2006;108:1377-1380.
-
(2006)
Blood
, vol.108
, pp. 1377-1380
-
-
Kralovics, R.1
Teo, S.S.2
Li, S.3
-
15
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med. 2006;3:e270.
-
(2006)
PLoS Med
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
-
16
-
-
27744606173
-
JAK2 mutation in essential thrombocythaemia: Clinical associations and long-term prognostic relevance
-
Wolanskyj AP, Lasho TL, Schwager SM, et al. JAK2 mutation in essential thrombocythaemia: clinical associations and long-term prognostic relevance. Br J Haematol. 2005;131:208-213.
-
(2005)
Br J Haematol
, vol.131
, pp. 208-213
-
-
Wolanskyj, A.P.1
Lasho, T.L.2
Schwager, S.M.3
-
17
-
-
30844456807
-
WHO histological classification of chronic myeloproliferative diseases
-
Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. Lyon, France: International Agency for Research on Cancer (IARC) Press
-
Vardiman JW, Brunning RD, Harris NL. WHO histological classification of chronic myeloproliferative diseases. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, eds. Tumours of the Haematopoietic and Lymphoid Tissues. Lyon, France: International Agency for Research on Cancer (IARC) Press; 2001:17-44.
-
(2001)
Tumours of the Haematopoietic and Lymphoid Tissues
, pp. 17-44
-
-
Vardiman, J.W.1
Brunning, R.D.2
Harris, N.L.3
-
18
-
-
21344440357
-
The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes
-
Steensma DP, Dewald GW, Lasho TL, et al. The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and myelodysplastic syndromes. Blood. 2005;106:1207-1209.
-
(2005)
Blood
, vol.106
, pp. 1207-1209
-
-
Steensma, D.P.1
Dewald, G.W.2
Lasho, T.L.3
-
19
-
-
33644969827
-
Validation of two clinically useful assays for evaluation of JAK2 V617F mutation in chronic myeloproliferative disorders
-
McClure R, Mai M, Lasho T. Validation of two clinically useful assays for evaluation of JAK2 V617F mutation in chronic myeloproliferative disorders. Leukemia. 2006;20:168-171.
-
(2006)
Leukemia
, vol.20
, pp. 168-171
-
-
McClure, R.1
Mai, M.2
Lasho, T.3
-
20
-
-
31544454193
-
Prognosis in transplant-eligible patients with agnogenic myeloid metaplasia: A simple CBC-based scoring system
-
Dingli D, Schwager SM, Mesa RA, Li CY, Tefferi A. Prognosis in transplant-eligible patients with agnogenic myeloid metaplasia: a simple CBC-based scoring system. Cancer. 2006;106:623-630.
-
(2006)
Cancer
, vol.106
, pp. 623-630
-
-
Dingli, D.1
Schwager, S.M.2
Mesa, R.A.3
Li, C.Y.4
Tefferi, A.5
-
21
-
-
33344455687
-
An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor
-
Staerk J, Lacout C, Sato T, Smith SO, Vainchenker W, Constantinescu SN. An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor. Blood. 2006;107:1864-1871.
-
(2006)
Blood
, vol.107
, pp. 1864-1871
-
-
Staerk, J.1
Lacout, C.2
Sato, T.3
Smith, S.O.4
Vainchenker, W.5
Constantinescu, S.N.6
-
22
-
-
2542502506
-
Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin
-
Ding J, Komatsu H, Wakita A, et al. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood. 2004;103:4198-4200.
-
(2004)
Blood
, vol.103
, pp. 4198-4200
-
-
Ding, J.1
Komatsu, H.2
Wakita, A.3
-
23
-
-
0036050145
-
A novel MPL point mutation resulting in thrombopoietin-independent activation
-
Abe M, Suzuki K, Inagaki O, Sassa S, Shikama H. A novel MPL point mutation resulting in thrombopoietin-independent activation. Leukemia. 2002;16:1500-1506.
-
(2002)
Leukemia
, vol.16
, pp. 1500-1506
-
-
Abe, M.1
Suzuki, K.2
Inagaki, O.3
Sassa, S.4
Shikama, H.5
-
24
-
-
33646546386
-
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
-
Jamieson CH, Gotlib J, Durocher JA, et al. The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation. Proc Natl Acad Sci U S A. 2006;103:6224-6229.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 6224-6229
-
-
Jamieson, C.H.1
Gotlib, J.2
Durocher, J.A.3
|