Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning

Blood

Volumn 121, Issue 6, 2013, Pages 5238-5249

  Olson, Timothy S ^a   Caselli, Anna ^b   Otsuru, Satoru ^a   Hofmann, Ted J ^a   Williams, Richard ^c,d   Paolucci, Paolo ^b   Dominici, Massimo ^b   Horwitz, Edwin M ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d Puma Biotechnology Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECAPLERMIN; IMATINIB; PLATELET DERIVED GROWTH FACTOR BB; RECOMBINANT THROMBOPOIETIN; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; MPL PROTEIN, MOUSE; PLATELET DERIVED GROWTH FACTOR B; PLATELET-DERIVED GROWTH FACTOR BB; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; DRUG MEGADOSE; ENGRAFTMENT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOLOGY; LOW DRUG DOSE; MEGAKARYOCYTE; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RADIOABLATIVE CONDITIONING; TRANSPLANTATION CONDITIONING; WHOLE BODY RADIATION; ANIMAL; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; GRAFT SURVIVAL; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; STEM CELL NICHE; VASCULAR ENDOTHELIUM;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MEGAKARYOCYTES; MICE; MICE, INBRED C57BL; OSTEOBLASTS; PROTO-ONCOGENE PROTEINS C-SIS; RECEPTORS, THROMBOPOIETIN; SIGNAL TRANSDUCTION; STEM CELL NICHE; THROMBOPOIETIN; WHOLE-BODY IRRADIATION;

EID: 84883571576     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-463414     Document Type: Article

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