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Volumn 15, Issue 5, 2009, Pages 566-571

Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CASPASE 3; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MYC PROTEIN; PROTEIN BCL 2; STAT3 PROTEIN; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

EID: 67349107068     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1903     Document Type: Article
Times cited : (108)

References (40)
  • 1
    • 0035865465 scopus 로고    scopus 로고
    • Cancer and genomics
    • Futreal, P.A. et al. Cancer and genomics. Nature 409, 850-852 (2001).
    • (2001) Nature , vol.409 , pp. 850-852
    • Futreal, P.A.1
  • 2
    • 1642512402 scopus 로고    scopus 로고
    • Tumour suppression: Putting on the brakes
    • Harris, H. Tumour suppression: putting on the brakes. Nature 427, 201 (2004).
    • (2004) Nature , vol.427 , pp. 201
    • Harris, H.1
  • 3
    • 23644449752 scopus 로고    scopus 로고
    • Cancer: Crime and punishment
    • Sharpless, N.E. & DePinho, R.A. Cancer: crime and punishment. Nature 436, 636-637 (2005).
    • (2005) Nature , vol.436 , pp. 636-637
    • Sharpless, N.E.1    DePinho, R.A.2
  • 4
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein, B. & Kinzler, K.W. Cancer genes and the pathways they control. Nat. Med. 10, 789-799 (2004).
    • (2004) Nat. Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 5
    • 0000538165 scopus 로고
    • Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
    • Dalla-Favera, R. et al. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl. Acad. Sci. USA 79, 7824-7827 (1982).
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 7824-7827
    • Dalla-Favera, R.1
  • 6
    • 33645792588 scopus 로고    scopus 로고
    • Burkitt's lymphoma: Clinicopathologic features and differential diagnosis
    • Ferry, J.A. Burkitt's lymphoma: clinicopathologic features and differential diagnosis. Oncologist 11, 375-383 (2006).
    • (2006) Oncologist , vol.11 , pp. 375-383
    • Ferry, J.A.1
  • 7
  • 8
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto, Y., Cossman, J., Jaffe, E. & Croce, C.M. Involvement of the bcl-2 gene in human follicular lymphoma. Science 228, 1440-1443 (1985).
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 9
    • 0034468109 scopus 로고    scopus 로고
    • Molecular diagnostics in follicular non-Hodgkin's lymphoma: A review
    • Bordeleau, L. & Berinstein, N.L. Molecular diagnostics in follicular non-Hodgkin's lymphoma: a review. Semin. Oncol. 27, 42-52 (2000).
    • (2000) Semin. Oncol , vol.27 , pp. 42-52
    • Bordeleau, L.1    Berinstein, N.L.2
  • 10
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo, T.G., Pendergast, A.M., Muller, A.J. & Witte, O.N. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 247, 1079-1082 (1990).
    • (1990) Science , vol.247 , pp. 1079-1082
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 11
    • 34249676964 scopus 로고    scopus 로고
    • Chronic myeloid leukaemia as a model of disease evolution in human cancer
    • Melo, J.V. & Barnes, D.J. Chronic myeloid leukaemia as a model of disease evolution in human cancer. Nat. Rev. Cancer 7, 441-453 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 441-453
    • Melo, J.V.1    Barnes, D.J.2
  • 12
    • 34247470836 scopus 로고    scopus 로고
    • Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
    • Weisberg, E., Manley, P.W., Cowan-Jacob, S.W., Hochhaus, A. & Griffin, J.D. Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia. Nat. Rev. Cancer 7, 345-356 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 345-356
    • Weisberg, E.1    Manley, P.W.2    Cowan-Jacob, S.W.3    Hochhaus, A.4    Griffin, J.D.5
  • 13
    • 0032841181 scopus 로고    scopus 로고
    • Growth factor independence and BCR/ABL transformation: Promise and pitfalls of murine model systems and assays
    • Ghaffari, S., Daley, G.Q. & Lodish, H.F. Growth factor independence and BCR/ABL transformation: promise and pitfalls of murine model systems and assays. Leukemia 13, 1200-1206 (1999).
    • (1999) Leukemia , vol.13 , pp. 1200-1206
    • Ghaffari, S.1    Daley, G.Q.2    Lodish, H.F.3
  • 14
    • 0038387495 scopus 로고    scopus 로고
    • Cancer revoked: Oncogenes as therapeutic targets
    • Felsher, D.W. Cancer revoked: oncogenes as therapeutic targets. Nat. Rev. Cancer 3, 375-380 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 375-380
    • Felsher, D.W.1
  • 15
    • 0742287062 scopus 로고    scopus 로고
    • Conditional animal models: A strategy to define when oncogenes will be effective targets to treat cancer
    • Giuriato, S., Rabin, K., Fan, A.C., Shachaf, C.M. & Felsher, D.W. Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer. Semin. Cancer Biol. 14, 3-11 (2004).
    • (2004) Semin. Cancer Biol , vol.14 , pp. 3-11
    • Giuriato, S.1    Rabin, K.2    Fan, A.C.3    Shachaf, C.M.4    Felsher, D.W.5
  • 16
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker, B.J. et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 344, 1031-1037 (2001).
    • (2001) N. Engl. J. Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1
  • 17
    • 0037186915 scopus 로고    scopus 로고
    • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    • Kantarjian, H. et al. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N. Engl. J. Med. 346, 645-652 (2002).
    • (2002) N. Engl. J. Med , vol.346 , pp. 645-652
    • Kantarjian, H.1
  • 18
    • 13844251975 scopus 로고    scopus 로고
    • Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
    • Weisberg, E. et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell 7, 129-141 (2005).
    • (2005) Cancer Cell , vol.7 , pp. 129-141
    • Weisberg, E.1
  • 19
    • 34247616777 scopus 로고    scopus 로고
    • Reduction of Bcr-Abl function leads to erythroid differentiation of K562 cells via downregulation of ERK
    • Brozik, A. et al. Reduction of Bcr-Abl function leads to erythroid differentiation of K562 cells via downregulation of ERK. Ann. NY Acad. Sci. 1090, 344-354 (2006).
    • (2006) Ann. NY Acad. Sci , vol.1090 , pp. 344-354
    • Brozik, A.1
  • 20
    • 1242317094 scopus 로고    scopus 로고
    • Different roles of p38 MAPKand ERK in STI571-induced multi-lineage differentiation of K562 cells
    • Kohmura, K., Miyakawa, Y, Kawai, Y, Ikeda, Y. & Kizaki, M. Different roles of p38 MAPKand ERK in STI571-induced multi-lineage differentiation of K562 cells. J. Cell. Physiol. 198, 370-376 (2004).
    • (2004) J. Cell. Physiol , vol.198 , pp. 370-376
    • Kohmura, K.1    Miyakawa, Y.2    Kawai, Y.3    Ikeda, Y.4    Kizaki, M.5
  • 21
    • 31144453233 scopus 로고    scopus 로고
    • BRAF mutation predicts sensitivity to MEK inhibition
    • Solit, D.B. et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature 439, 358-362 (2006).
    • (2006) Nature , vol.439 , pp. 358-362
    • Solit, D.B.1
  • 22
    • 33750868447 scopus 로고    scopus 로고
    • Isoelectric focusing technology quantifies protein signaling in 25 cells
    • O'Neill, R.A. et al. Isoelectric focusing technology quantifies protein signaling in 25 cells. Proc. Natl. Acad. Sci. USA 103, 16153-16158 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16153-16158
    • O'Neill, R.A.1
  • 23
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • Felsher, D.W. & Bishop, J.M. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207 (1999).
    • (1999) Mol. Cell , vol.4 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 24
    • 0038107350 scopus 로고    scopus 로고
    • Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations
    • Karlsson, A. et al. Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations. Bloodl 101, 2797-2803 (2003).
    • (2003) Bloodl , vol.101 , pp. 2797-2803
    • Karlsson, A.1
  • 25
    • 33750800316 scopus 로고    scopus 로고
    • Sustained regression of tumors upon MYC inactivation requires p53 orthrombospondin-1 to reverse the angiogenic switch
    • Giuriato, S. et al. Sustained regression of tumors upon MYC inactivation requires p53 orthrombospondin-1 to reverse the angiogenic switch. Proc. Natl. Acad. Sci. USA 103, 16266-16271 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16266-16271
    • Giuriato, S.1
  • 26
    • 34948863375 scopus 로고    scopus 로고
    • Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis
    • Shachaf, CM. et al. Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. Bloodl 110, 2674-2684 (2007).
    • (2007) Bloodl , vol.110 , pp. 2674-2684
    • Shachaf, C.M.1
  • 27
    • 0023797425 scopus 로고
    • Expression of c-myc oncogene product and ras family oncogene products in various human malignant lymphomas defined by immunohistochemical techniques
    • Mitani, S., Sugawara, I., Shiku, H. & Mori, S. Expression of c-myc oncogene product and ras family oncogene products in various human malignant lymphomas defined by immunohistochemical techniques. Cancer 62, 2085-2093 (1988).
    • (1988) Cancer , vol.62 , pp. 2085-2093
    • Mitani, S.1    Sugawara, I.2    Shiku, H.3    Mori, S.4
  • 28
    • 0026325308 scopus 로고
    • Differential c-myc protein expression in Burkitt's lymphomas and EBV-transformed lymphoblastoid lines
    • Wennborg, A.D., Altiok, E., Moore, J.P., Ernberg, I. & Klein, G. Differential c-myc protein expression in Burkitt's lymphomas and EBV-transformed lymphoblastoid lines. Eur. J. Cancer 27, 1643-1645 (1991).
    • (1991) Eur. J. Cancer , vol.27 , pp. 1643-1645
    • Wennborg, A.D.1    Altiok, E.2    Moore, J.P.3    Ernberg, I.4    Klein, G.5
  • 29
    • 57149085478 scopus 로고    scopus 로고
    • Prognostic significance of secondary cytogenetic alterations in follicular lymphomas
    • Johnson, N.A. et al. Prognostic significance of secondary cytogenetic alterations in follicular lymphomas. Genes Chromosom. Cancer 47, 1038-1048 (2008).
    • (2008) Genes Chromosom. Cancer , vol.47 , pp. 1038-1048
    • Johnson, N.A.1
  • 30
    • 0021688655 scopus 로고
    • Proteins encoded by the human c-myc oncogene: Differential expression in neoplastic cells
    • Hann, S.R. & Eisenman, R.N. Proteins encoded by the human c-myc oncogene: differential expression in neoplastic cells. Mol. Cell. Biol. 4, 2486-2497 (1984).
    • (1984) Mol. Cell. Biol , vol.4 , pp. 2486-2497
    • Hann, S.R.1    Eisenman, R.N.2
  • 31
    • 3142636201 scopus 로고
    • The protein encoded by the human proto-oncogene c-myc
    • Ramsay, G., Evan, G.I. & Bishop, J.M. The protein encoded by the human proto-oncogene c-myc. Proc. Natl. Acad. Sci. USA 81, 7742-7746 (1984).
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7742-7746
    • Ramsay, G.1    Evan, G.I.2    Bishop, J.M.3
  • 32
    • 0037082504 scopus 로고    scopus 로고
    • Germinal center phenotypeand bc l-2 expression combined with the International Prognostic Index improves patient risk stratification in diffuse large B-cell lymphoma
    • Barrans, S.L. etal. Germinal center phenotypeand bc l-2 expression combined with the International Prognostic Index improves patient risk stratification in diffuse large B-cell lymphoma. Bloodl 99, 1136-1143 (2002).
    • (2002) Bloodl , vol.99 , pp. 1136-1143
    • Barrans, S.L.1
  • 33
    • 0037217921 scopus 로고    scopus 로고
    • Clinical impact of the differentiation profile assessed by immuno-phenotyping in patients with diffuse large B-cell lymphoma
    • Colomo, L. et al. Clinical impact of the differentiation profile assessed by immuno-phenotyping in patients with diffuse large B-cell lymphoma. Bloodl 101, 78-84 (2003).
    • (2003) Bloodl , vol.101 , pp. 78-84
    • Colomo, L.1
  • 34
    • 0030985194 scopus 로고    scopus 로고
    • Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma
    • Gascoyne, R.D. et al. Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma. Bloodl 90, 244-251 (1997).
    • (1997) Bloodl , vol.90 , pp. 244-251
    • Gascoyne, R.D.1
  • 35
    • 55749114922 scopus 로고    scopus 로고
    • IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma
    • Calvo, K.R. etal. IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma. Bloodl 112, 3818-3826 (2008).
    • (2008) Bloodl , vol.112 , pp. 3818-3826
    • Calvo, K.R.1
  • 36
    • 0037838920 scopus 로고    scopus 로고
    • Nodal marginal zone lymphoma: A heterogeneous tumor: a comprehensive analysis of a series of 27 cases
    • Camacho, F.I. et al. Nodal marginal zone lymphoma: a heterogeneous tumor: a comprehensive analysis of a series of 27 cases. Am. J. Surg. Pathol. 27, 762-771 (2003).
    • (2003) Am. J. Surg. Pathol , vol.27 , pp. 762-771
    • Camacho, F.I.1
  • 37
    • 13344269022 scopus 로고    scopus 로고
    • Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features
    • Dierlamm, J. et al. Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features. Bloodl 87, 299-307 (1996).
    • (1996) Bloodl , vol.87 , pp. 299-307
    • Dierlamm, J.1
  • 38
    • 33751195937 scopus 로고    scopus 로고
    • Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells
    • Irish, J.M., Czerwinski, D.K., Nolan, G.P. & Levy, R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Bloodl 108, 3135-3142 (2006).
    • (2006) Bloodl , vol.108 , pp. 3135-3142
    • Irish, J.M.1    Czerwinski, D.K.2    Nolan, G.P.3    Levy, R.4
  • 39
    • 40149105001 scopus 로고    scopus 로고
    • Lee, T., Yao, G., Nevins, J. & You, L. Sensingand integration of Erkand PI3Ksignals by Myc. PLOS Comput. Biol. 4, e1000013 (2008).
    • Lee, T., Yao, G., Nevins, J. & You, L. Sensingand integration of Erkand PI3Ksignals by Myc. PLOS Comput. Biol. 4, e1000013 (2008).
  • 40
    • 0042622251 scopus 로고    scopus 로고
    • Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
    • Obenauer, J.C., Cantley, L.C.&Yaffe, M.B. Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res. 31, 3635-3641 (2003).
    • (2003) Nucleic Acids Res , vol.31 , pp. 3635-3641
    • Obenauer, J.C.1    Cantley, L.C.2    Yaffe, M.B.3


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