Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 7, 2007, Pages 2349-2354

  Seita, Jun ^a,c   Ema, Hideo ^a   Ooehara, Jun ^a   Yamazaki, Satoshi ^a,b   Tadokoro, Yuko ^a   Yamasaki, Akiko ^a   Eto, Koji ^a   Takaki, Satoshi ^a   Takatsu, Kiyoshi ^a   Nakauchi, Hiromitsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b ReproCELL Inc   (Japan)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; c mpl; p38 MAPK; STAT5

Indexed keywords

ADAPTOR PROTEIN; ATAXIN 1; CD34 ANTIGEN; INTERLEUKIN 11; INTERLEUKIN 3; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B BETA; PROTEIN LNK; STAT5 PROTEIN; STEM CELL FACTOR; THROMBOPOIETIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL RENEWAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMATOPOIETIC STEM CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THROMBOGENESIS;

ANIMALS; CELL DIVISION; CELLS, CULTURED; CYTOKINES; HEMATOPOIETIC STEM CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN KINASES; PROTEINS; SIGNAL TRANSDUCTION; THROMBOPOIETIN;

MUS;

EID: 33847772982     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606238104     Document Type: Article

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