ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response

Cell Death and Differentiation

Volumn 17, Issue 11, 2010, Pages 1739-1750

  Pawlikowska, P ^a,b   Leray, I ^a,b   De Laval, B ^a,b   Guihard, S ^a,b   Kumar, R ^c   Rosselli, F ^d   Porteu, F ^a,b  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c MAYO CLINIC   (United States)

^d INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

apoptosis; checkpoint; DNA damage; IEX 1; Mcl 1

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; HYDROXYUREA; PROTEIN; PROTEIN IEX 1; PROTEIN MCL 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL STRESS; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GAMMA IRRADIATION; GENE REPLICATION; GENOMIC INSTABILITY; GENOTOXICITY; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; TUMOR CELL; TUMOR RESISTANCE; WILD TYPE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE PROTEINS; CELL NUCLEUS; DNA DAMAGE; DNA-BINDING PROTEINS; GENES, BCL-2; GENOMIC INSTABILITY; HUMANS; IMMEDIATE-EARLY PROTEINS; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MITOSIS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 77957838263     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2010.56     Document Type: Article

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