메뉴 건너뛰기




Volumn 1, Issue 6, 2007, Pages 671-684

Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells

Author keywords

STEMCELL

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2D; HOX PROTEIN; PROTEIN BCL 2; PROTEIN P57; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR;

EID: 36749001043     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2007.10.008     Document Type: Article
Times cited : (429)

References (58)
  • 1
    • 20244387299 scopus 로고    scopus 로고
    • Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson J., Mansson R., Buza-Vidas N., Hultquist A., Liuba K., Jensen C.T., Bryder D., Yang L., Borge O.J., Thoren L.A., et al. Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell 121 (2005) 295-306
    • (2005) Cell , vol.121 , pp. 295-306
    • Adolfsson, J.1    Mansson, R.2    Buza-Vidas, N.3    Hultquist, A.4    Liuba, K.5    Jensen, C.T.6    Bryder, D.7    Yang, L.8    Borge, O.J.9    Thoren, L.A.10
  • 2
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi K., Kondo M., von Freeden-Jeffry U., Murray R., and Weissman I.L. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89 (1997) 1033-1041
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 3
    • 0029960265 scopus 로고    scopus 로고
    • Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl
    • Alexander W.S., Roberts A.W., Nicola N.A., Li R., and Metcalf D. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl. Blood 87 (1996) 2162-2170
    • (1996) Blood , vol.87 , pp. 2162-2170
    • Alexander, W.S.1    Roberts, A.W.2    Nicola, N.A.3    Li, R.4    Metcalf, D.5
  • 4
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J., Sauvageau G., and Humphries R.K. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109 (2002) 39-45
    • (2002) Cell , vol.109 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 5
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., Ito K., Koh G.Y., and Suda T. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118 (2004) 149-161
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 6
    • 0038129842 scopus 로고    scopus 로고
    • Thrombopoietin is essential for the maintenance of normal hematopoiesis in humans: development of aplastic anemia in patients with congenital amegakaryocytic thrombocytopenia
    • Ballmaier M., Germeshausen M., Krukemeier S., and Welte K. Thrombopoietin is essential for the maintenance of normal hematopoiesis in humans: development of aplastic anemia in patients with congenital amegakaryocytic thrombocytopenia. Ann. N Y Acad. Sci. 996 (2003) 17-25
    • (2003) Ann. N Y Acad. Sci. , vol.996 , pp. 17-25
    • Ballmaier, M.1    Germeshausen, M.2    Krukemeier, S.3    Welte, K.4
  • 7
    • 0029858989 scopus 로고    scopus 로고
    • Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro
    • Borge O.J., Ramsfjell V., Veiby O.P., Murphy Jr. M.J., Lok S., and Jacobsen S.E. Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro. Blood 88 (1996) 2859-2870
    • (1996) Blood , vol.88 , pp. 2859-2870
    • Borge, O.J.1    Ramsfjell, V.2    Veiby, O.P.3    Murphy Jr., M.J.4    Lok, S.5    Jacobsen, S.E.6
  • 8
    • 33749452454 scopus 로고    scopus 로고
    • Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
    • Bowie M.B., McKnight K.D., Kent D.G., McCaffrey L., Hoodless P.A., and Eaves C.J. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J. Clin. Invest. 116 (2006) 2808-2816
    • (2006) J. Clin. Invest. , vol.116 , pp. 2808-2816
    • Bowie, M.B.1    McKnight, K.D.2    Kent, D.G.3    McCaffrey, L.4    Hoodless, P.A.5    Eaves, C.J.6
  • 9
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
    • Bradford G.B., Williams B., Rossi R., and Bertoncello I. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp. Hematol. 25 (1997) 445-453
    • (1997) Exp. Hematol. , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 10
    • 0034283746 scopus 로고    scopus 로고
    • Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro
    • Bryder D., and Jacobsen S.E. Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro. Blood 96 (2000) 1748-1755
    • (2000) Blood , vol.96 , pp. 1748-1755
    • Bryder, D.1    Jacobsen, S.E.2
  • 13
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • Cheng T., Rodrigues N., Dombkowski D., Stier S., and Scadden D.T. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat. Med. 6 (2000) 1235-1240
    • (2000) Nat. Med. , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 15
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier S.H., Morrison S.J., Liao X., and Weissman I.L. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 96 (1999) 3120-3125
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 16
    • 0026025755 scopus 로고
    • Growth factors in development, transformation, and tumorigenesis
    • Cross M., and Dexter T.M. Growth factors in development, transformation, and tumorigenesis. Cell 64 (1991) 271-280
    • (1991) Cell , vol.64 , pp. 271-280
    • Cross, M.1    Dexter, T.M.2
  • 18
    • 0032055166 scopus 로고    scopus 로고
    • Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation
    • Domen J., Gandy K.L., and Weissman I.L. Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91 (1998) 2272-2282
    • (1998) Blood , vol.91 , pp. 2272-2282
    • Domen, J.1    Gandy, K.L.2    Weissman, I.L.3
  • 21
    • 0034613735 scopus 로고    scopus 로고
    • In vitro self-renewal division of hematopoietic stem cells
    • Ema H., Takano H., Sudo K., and Nakauchi H. In vitro self-renewal division of hematopoietic stem cells. J. Exp. Med. 192 (2000) 1281-1288
    • (2000) J. Exp. Med. , vol.192 , pp. 1281-1288
    • Ema, H.1    Takano, H.2    Sudo, K.3    Nakauchi, H.4
  • 22
    • 0036330339 scopus 로고    scopus 로고
    • Thrombopoietin expands hematopoietic stem cells after transplantation
    • Fox N., Priestley G., Papayannopoulou T., and Kaushansky K. Thrombopoietin expands hematopoietic stem cells after transplantation. J. Clin. Invest. 110 (2002) 389-394
    • (2002) J. Clin. Invest. , vol.110 , pp. 389-394
    • Fox, N.1    Priestley, G.2    Papayannopoulou, T.3    Kaushansky, K.4
  • 24
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
    • Hock H., Hamblen M.J., Rooke H.M., Schindler J.W., Saleque S., Fujiwara Y., and Orkin S.H. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature 431 (2004) 1002-1007
    • (2004) Nature , vol.431 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3    Schindler, J.W.4    Saleque, S.5    Fujiwara, Y.6    Orkin, S.H.7
  • 25
    • 0031260589 scopus 로고    scopus 로고
    • Hematopoietic stem cells expand during serial transplantation in vivo without apparent exhaustion
    • Iscove N.N., and Nawa K. Hematopoietic stem cells expand during serial transplantation in vivo without apparent exhaustion. Curr. Biol. 7 (1997) 805-808
    • (1997) Curr. Biol. , vol.7 , pp. 805-808
    • Iscove, N.N.1    Nawa, K.2
  • 26
    • 0029090437 scopus 로고
    • Thrombopoietin: the primary regulator of megakaryocyte and platelet production
    • Kaushansky K. Thrombopoietin: the primary regulator of megakaryocyte and platelet production. Thromb. Haemost. 74 (1995) 521-525
    • (1995) Thromb. Haemost. , vol.74 , pp. 521-525
    • Kaushansky, K.1
  • 27
    • 33646490285 scopus 로고    scopus 로고
    • Lineage-specific hematopoietic growth factors
    • Kaushansky K. Lineage-specific hematopoietic growth factors. N. Engl. J. Med. 354 (2006) 2034-2045
    • (2006) N. Engl. J. Med. , vol.354 , pp. 2034-2045
    • Kaushansky, K.1
  • 28
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel M.J., Yilmaz O.H., Iwashita T., Terhorst C., and Morrison S.J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (2005) 1109-1121
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 29
    • 0032477741 scopus 로고    scopus 로고
    • Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
    • Kimura S., Roberts A.W., Metcalf D., and Alexander W.S. Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. Proc. Natl. Acad. Sci. USA 95 (1998) 1195-1200
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1195-1200
    • Kimura, S.1    Roberts, A.W.2    Metcalf, D.3    Alexander, W.S.4
  • 30
    • 3242665129 scopus 로고    scopus 로고
    • Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells
    • Kirito K., Fox N., and Kaushansky K. Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells. Mol. Cell. Biol. 24 (2004) 6751-6762
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 6751-6762
    • Kirito, K.1    Fox, N.2    Kaushansky, K.3
  • 31
    • 0031587848 scopus 로고    scopus 로고
    • Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice
    • Lagasse E., and Weissman I.L. Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell 89 (1997) 1021-1031
    • (1997) Cell , vol.89 , pp. 1021-1031
    • Lagasse, E.1    Weissman, I.L.2
  • 32
    • 28444455240 scopus 로고    scopus 로고
    • Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells
    • Lawrence H.J., Christensen J., Fong S., Hu Y.L., Weissman I., Sauvageau G., Humphries R.K., and Largman C. Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood 106 (2005) 3988-3994
    • (2005) Blood , vol.106 , pp. 3988-3994
    • Lawrence, H.J.1    Christensen, J.2    Fong, S.3    Hu, Y.L.4    Weissman, I.5    Sauvageau, G.6    Humphries, R.K.7    Largman, C.8
  • 33
    • 0032519768 scopus 로고    scopus 로고
    • c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities
    • Lyman S.D., and Jacobsen S.E. c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood 91 (1998) 1101-1134
    • (1998) Blood , vol.91 , pp. 1101-1134
    • Lyman, S.D.1    Jacobsen, S.E.2
  • 35
    • 0031587875 scopus 로고    scopus 로고
    • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice
    • Maraskovsky E., O'Reilly L.A., Teepe M., Corcoran L.M., Peschon J.J., and Strasser A. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell 89 (1997) 1011-1019
    • (1997) Cell , vol.89 , pp. 1011-1019
    • Maraskovsky, E.1    O'Reilly, L.A.2    Teepe, M.3    Corcoran, L.M.4    Peschon, J.J.5    Strasser, A.6
  • 36
    • 0027136259 scopus 로고
    • Hematopoietic regulators: redundancy or subtlety?
    • Metcalf D. Hematopoietic regulators: redundancy or subtlety?. Blood 82 (1993) 3515-3523
    • (1993) Blood , vol.82 , pp. 3515-3523
    • Metcalf, D.1
  • 39
    • 0141636530 scopus 로고    scopus 로고
    • Phenotype and hematopoietic potential of side population cells throughout embryonic development
    • Nadin B.M., Goodell M.A., and Hirschi K.K. Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood 102 (2003) 2436-2443
    • (2003) Blood , vol.102 , pp. 2436-2443
    • Nadin, B.M.1    Goodell, M.A.2    Hirschi, K.K.3
  • 40
    • 33745322046 scopus 로고    scopus 로고
    • Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property
    • Nygren J.M., Bryder D., and Jacobsen S.E. Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property. J. Immunol. 177 (2006) 201-208
    • (2006) J. Immunol. , vol.177 , pp. 201-208
    • Nygren, J.M.1    Bryder, D.2    Jacobsen, S.E.3
  • 41
    • 0027325195 scopus 로고
    • Differentiation and proliferation of hematopoietic stem cells
    • Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 81 (1993) 2844-2853
    • (1993) Blood , vol.81 , pp. 2844-2853
    • Ogawa, M.1
  • 42
    • 0032912656 scopus 로고    scopus 로고
    • Cell division tracking and expansion of hematopoietic long-term repopulating cells
    • Oostendorp R.A., Audet J., Miller C., and Eaves C.J. Cell division tracking and expansion of hematopoietic long-term repopulating cells. Leukemia 13 (1999) 499-501
    • (1999) Leukemia , vol.13 , pp. 499-501
    • Oostendorp, R.A.1    Audet, J.2    Miller, C.3    Eaves, C.J.4
  • 43
    • 0029909363 scopus 로고    scopus 로고
    • Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo
    • Pawliuk R., Eaves C., and Humphries R.K. Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo. Blood 88 (1996) 2852-2858
    • (1996) Blood , vol.88 , pp. 2852-2858
    • Pawliuk, R.1    Eaves, C.2    Humphries, R.K.3
  • 44
    • 0242331643 scopus 로고    scopus 로고
    • Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis
    • Puri M.C., and Bernstein A. Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis. Proc. Natl. Acad. Sci. USA 100 (2003) 12753-12758
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12753-12758
    • Puri, M.C.1    Bernstein, A.2
  • 45
    • 5444224800 scopus 로고    scopus 로고
    • In vitro and in vivo expansion of hematopoietic stem cells
    • Sauvageau G., Iscove N.N., and Humphries R.K. In vitro and in vivo expansion of hematopoietic stem cells. Oncogene 23 (2004) 7223-7232
    • (2004) Oncogene , vol.23 , pp. 7223-7232
    • Sauvageau, G.1    Iscove, N.N.2    Humphries, R.K.3
  • 46
    • 0030014681 scopus 로고    scopus 로고
    • The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells
    • Sitnicka E., Lin N., Priestley G.V., Fox N., Broudy V.C., Wolf N.S., and Kaushansky K. The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells. Blood 87 (1996) 4998-5005
    • (1996) Blood , vol.87 , pp. 4998-5005
    • Sitnicka, E.1    Lin, N.2    Priestley, G.V.3    Fox, N.4    Broudy, V.C.5    Wolf, N.S.6    Kaushansky, K.7
  • 48
    • 8544252411 scopus 로고    scopus 로고
    • Clinical strategies for expansion of haematopoietic stem cells
    • Sorrentino B.P. Clinical strategies for expansion of haematopoietic stem cells. Nat. Rev. Immunol. 4 (2004) 878-888
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 878-888
    • Sorrentino, B.P.1
  • 49
    • 0025205255 scopus 로고
    • Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy
    • Szilvassy S.J., Humphries R.K., Lansdorp P.M., Eaves A.C., and Eaves C.J. Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. Proc. Natl. Acad. Sci. USA 87 (1990) 8736-8740
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8736-8740
    • Szilvassy, S.J.1    Humphries, R.K.2    Lansdorp, P.M.3    Eaves, A.C.4    Eaves, C.J.5
  • 50
    • 0032828743 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells
    • Tschan M.P., Peters U.R., Cajot J.F., Betticher D.C., Fey M.F., and Tobler A. The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells. Br. J. Haematol. 106 (1999) 644-651
    • (1999) Br. J. Haematol. , vol.106 , pp. 644-651
    • Tschan, M.P.1    Peters, U.R.2    Cajot, J.F.3    Betticher, D.C.4    Fey, M.F.5    Tobler, A.6
  • 51
    • 33644827383 scopus 로고    scopus 로고
    • Bone-marrow haematopoietic-stem-cell niches
    • Wilson A., and Trumpp A. Bone-marrow haematopoietic-stem-cell niches. Nat. Rev. Immunol. 6 (2006) 93-106
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 93-106
    • Wilson, A.1    Trumpp, A.2
  • 52
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki S., Iwama A., Takayanagi S., Morita Y., Eto K., Ema H., and Nakauchi H. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25 (2006) 3515-3523
    • (2006) EMBO J. , vol.25 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Morita, Y.4    Eto, K.5    Ema, H.6    Nakauchi, H.7
  • 53
    • 15944363056 scopus 로고    scopus 로고
    • Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
    • Yang L., Bryder D., Adolfsson J., Nygren J., Mansson R., Sigvardsson M., and Jacobsen S.E. Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood 105 (2005) 2717-2723
    • (2005) Blood , vol.105 , pp. 2717-2723
    • Yang, L.1    Bryder, D.2    Adolfsson, J.3    Nygren, J.4    Mansson, R.5    Sigvardsson, M.6    Jacobsen, S.E.7
  • 54
    • 31544481865 scopus 로고    scopus 로고
    • SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity
    • Yilmaz O.H., Kiel M.J., and Morrison S.J. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood 107 (2006) 924-930
    • (2006) Blood , vol.107 , pp. 924-930
    • Yilmaz, O.H.1    Kiel, M.J.2    Morrison, S.J.3
  • 55
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., and Morrison S.J. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3    Guo, W.4    Ferguson, D.O.5    Wu, H.6    Morrison, S.J.7
  • 58
    • 0037071391 scopus 로고    scopus 로고
    • Hematopoietic cytokines, transcription factors and lineage commitment
    • Zhu J., and Emerson S.G. Hematopoietic cytokines, transcription factors and lineage commitment. Oncogene 21 (2002) 3295-3313
    • (2002) Oncogene , vol.21 , pp. 3295-3313
    • Zhu, J.1    Emerson, S.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.