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Volumn 41, Issue 8, 2013, Pages 665-674

Myelodysplastic syndrome: An inability to appropriately respond to damaged DNA?

Author keywords

[No Author keywords available]

Indexed keywords

FLUDARABINE; HISTONE H2AX; TEMOZOLOMIDE;

EID: 84880755300     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2013.04.008     Document Type: Review
Times cited : (31)

References (108)
  • 1
    • 52949153952 scopus 로고    scopus 로고
    • Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell
    • Chung Y.J., Choi C.W., Slape C., Fry T., Aplan P.D. Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell. Proc Natl Acad Sci USA 2008, 105:14088-14093.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14088-14093
    • Chung, Y.J.1    Choi, C.W.2    Slape, C.3    Fry, T.4    Aplan, P.D.5
  • 2
    • 35548954717 scopus 로고    scopus 로고
    • The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes
    • Nilsson L., Eden P., Olsson E., et al. The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes. Blood 2007, 110:3005-3014.
    • (2007) Blood , vol.110 , pp. 3005-3014
    • Nilsson, L.1    Eden, P.2    Olsson, E.3
  • 3
    • 84862554715 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: 2012 update on diagnosis, risk-stratification, and management
    • Garcia-Manero G. Myelodysplastic syndromes: 2012 update on diagnosis, risk-stratification, and management. Am J Hematol 2012, 87:692-701.
    • (2012) Am J Hematol , vol.87 , pp. 692-701
    • Garcia-Manero, G.1
  • 4
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    • Vardiman J.W., Thiele J., Arber D.A., et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009, 114:937-951.
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 5
    • 84862840164 scopus 로고    scopus 로고
    • Epidemiology of myelodysplastic syndromes
    • Ma X. Epidemiology of myelodysplastic syndromes. Am J Med 2012, 125:S2-S5.
    • (2012) Am J Med , vol.125
    • Ma, X.1
  • 6
    • 20144363122 scopus 로고    scopus 로고
    • Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer-an update
    • Barnard D.R., Woods W.G. Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer-an update. Leuk Lymphoma 2005, 46:651-663.
    • (2005) Leuk Lymphoma , vol.46 , pp. 651-663
    • Barnard, D.R.1    Woods, W.G.2
  • 7
    • 79952041645 scopus 로고    scopus 로고
    • Treatment-related myelodysplastic syndrome: molecular characteristics and therapy
    • Bhatia R., Deeg H.J. Treatment-related myelodysplastic syndrome: molecular characteristics and therapy. Curr Opin Hematol 2011, 18:77-82.
    • (2011) Curr Opin Hematol , vol.18 , pp. 77-82
    • Bhatia, R.1    Deeg, H.J.2
  • 8
    • 34447300991 scopus 로고    scopus 로고
    • Myelodysplastic syndromes in children: A critical review of issues in the diagnosis and classification of 887 cases from 13 published series
    • Elghetany M.T. Myelodysplastic syndromes in children: A critical review of issues in the diagnosis and classification of 887 cases from 13 published series. Arch Pathol Lab Med 2007, 131:1110-1116.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1110-1116
    • Elghetany, M.T.1
  • 9
    • 77950630063 scopus 로고    scopus 로고
    • Incidence and susceptibility to therapy-related myeloid neoplasms
    • Leone G., Fianchi L., Pagano L., Voso M.T. Incidence and susceptibility to therapy-related myeloid neoplasms. Chem Biol Interact 2010, 184:39-45.
    • (2010) Chem Biol Interact , vol.184 , pp. 39-45
    • Leone, G.1    Fianchi, L.2    Pagano, L.3    Voso, M.T.4
  • 10
    • 73949143725 scopus 로고    scopus 로고
    • Diagnosis of myelodysplastic syndrome among a cohort of 119 patients with fanconi anemia: Morphologic and cytogenetic characteristics
    • Cioc A.M., Wagner J.E., MacMillan M.L., DeFor T., Hirsch B. Diagnosis of myelodysplastic syndrome among a cohort of 119 patients with fanconi anemia: Morphologic and cytogenetic characteristics. Am J Clin Pathol 2010, 133:92-100.
    • (2010) Am J Clin Pathol , vol.133 , pp. 92-100
    • Cioc, A.M.1    Wagner, J.E.2    MacMillan, M.L.3    DeFor, T.4    Hirsch, B.5
  • 11
    • 0026668362 scopus 로고
    • Experience in pediatric myelodysplastic syndromes
    • Gadner H., Haas O.A. Experience in pediatric myelodysplastic syndromes. Hematol Oncol Clin North Am 1992, 6:655-672.
    • (1992) Hematol Oncol Clin North Am , vol.6 , pp. 655-672
    • Gadner, H.1    Haas, O.A.2
  • 16
    • 0035396754 scopus 로고    scopus 로고
    • Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies
    • Poppe B., Van Limbergen H., Van Roy N., et al. Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies. Cancer Genet Cytogenet 2001, 128:39-42.
    • (2001) Cancer Genet Cytogenet , vol.128 , pp. 39-42
    • Poppe, B.1    Van Limbergen, H.2    Van Roy, N.3
  • 17
    • 0030076795 scopus 로고    scopus 로고
    • Myelodysplastic syndrome in a child with Rothmund-Thomson syndrome: A case report
    • Rizzari C., Bacchiocchi D., Rovelli A., et al. Myelodysplastic syndrome in a child with Rothmund-Thomson syndrome: A case report. J Pediatr Hematol Oncol 1996, 18:96-97.
    • (1996) J Pediatr Hematol Oncol , vol.18 , pp. 96-97
    • Rizzari, C.1    Bacchiocchi, D.2    Rovelli, A.3
  • 18
    • 77954332797 scopus 로고    scopus 로고
    • Myelodysplastic syndromes arising in patients with germline TP53 mutation and Li-Fraumeni syndrome
    • Talwalkar S.S., Yin C.C., Naeem R.C., Hicks M.J., Strong L.C., Abruzzo L.V. Myelodysplastic syndromes arising in patients with germline TP53 mutation and Li-Fraumeni syndrome. Arch Pathol Lab Med 2010, 134:1010-1015.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 1010-1015
    • Talwalkar, S.S.1    Yin, C.C.2    Naeem, R.C.3    Hicks, M.J.4    Strong, L.C.5    Abruzzo, L.V.6
  • 20
    • 39649094569 scopus 로고    scopus 로고
    • New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients
    • Haase D., Germing U., Schanz J., et al. New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients. Blood 2007, 110:4385-4395.
    • (2007) Blood , vol.110 , pp. 4385-4395
    • Haase, D.1    Germing, U.2    Schanz, J.3
  • 21
    • 79952164235 scopus 로고    scopus 로고
    • Unraveling the molecular pathophysiology of myelodysplastic syndromes
    • Bejar R., Levine R., Ebert B.L. Unraveling the molecular pathophysiology of myelodysplastic syndromes. J Clin Oncol 2011, 29:504-515.
    • (2011) J Clin Oncol , vol.29 , pp. 504-515
    • Bejar, R.1    Levine, R.2    Ebert, B.L.3
  • 22
    • 77957146789 scopus 로고    scopus 로고
    • The molecular pathogenesis of myelodysplastic syndromes
    • Davids M.S., Steensma D.P. The molecular pathogenesis of myelodysplastic syndromes. Cancer Biol Ther 2010, 10:309-319.
    • (2010) Cancer Biol Ther , vol.10 , pp. 309-319
    • Davids, M.S.1    Steensma, D.P.2
  • 24
    • 84870221419 scopus 로고    scopus 로고
    • The genetic basis of phenotypic heterogeneity in myelodysplastic syndromes
    • Raza A., Galili N. The genetic basis of phenotypic heterogeneity in myelodysplastic syndromes. Nat Rev Cancer 2012, 12:849-859.
    • (2012) Nat Rev Cancer , vol.12 , pp. 849-859
    • Raza, A.1    Galili, N.2
  • 25
    • 0034890863 scopus 로고    scopus 로고
    • Hematologic malignancies
    • Gilliland D.G. Hematologic malignancies. Curr Opin Hematol 2001, 8:189-191.
    • (2001) Curr Opin Hematol , vol.8 , pp. 189-191
    • Gilliland, D.G.1
  • 26
    • 50849085449 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: molecular pathogenesis and genomic changes
    • Nolte F., Hofmann W.K. Myelodysplastic syndromes: molecular pathogenesis and genomic changes. Annals of hematology 2008, 87:777-795.
    • (2008) Annals of hematology , vol.87 , pp. 777-795
    • Nolte, F.1    Hofmann, W.K.2
  • 27
    • 0024402407 scopus 로고
    • Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes: a multivariate analysis of prognostic factors in 370 patients
    • Sanz G.F., Sanz M.A., Vallespi T., et al. Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes: a multivariate analysis of prognostic factors in 370 patients. Blood 1989, 74:395-408.
    • (1989) Blood , vol.74 , pp. 395-408
    • Sanz, G.F.1    Sanz, M.A.2    Vallespi, T.3
  • 28
    • 22044450619 scopus 로고    scopus 로고
    • NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
    • Lin Y.W., Slape C., Zhang Z., Aplan P.D. NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. Blood 2005, 106:287-295.
    • (2005) Blood , vol.106 , pp. 287-295
    • Lin, Y.W.1    Slape, C.2    Zhang, Z.3    Aplan, P.D.4
  • 29
    • 33749185394 scopus 로고    scopus 로고
    • SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice
    • Ma Y., Cui W., Yang J., et al. SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice. Blood 2006, 108:2726-2735.
    • (2006) Blood , vol.108 , pp. 2726-2735
    • Ma, Y.1    Cui, W.2    Yang, J.3
  • 30
    • 43249103972 scopus 로고    scopus 로고
    • AML1 mutations induced MDS and MDS/AML in a mouse BMT model
    • Watanabe-Okochi N., Kitaura J., Ono R., et al. AML1 mutations induced MDS and MDS/AML in a mouse BMT model. Blood 2008, 111:4297-4308.
    • (2008) Blood , vol.111 , pp. 4297-4308
    • Watanabe-Okochi, N.1    Kitaura, J.2    Ono, R.3
  • 31
    • 51749123590 scopus 로고    scopus 로고
    • Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes
    • Wu M.Y., Eldin K.W., Beaudet A.L. Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes. J Natl Cancer Inst 2008, 100:1247-1259.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1247-1259
    • Wu, M.Y.1    Eldin, K.W.2    Beaudet, A.L.3
  • 32
    • 84862805858 scopus 로고    scopus 로고
    • Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm
    • Zimmer S.N., Lemieux M.E., Karia B.P., et al. Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm. Exp Hematol 2012, 40:295-306.e295.
    • (2012) Exp Hematol , vol.40
    • Zimmer, S.N.1    Lemieux, M.E.2    Karia, B.P.3
  • 33
    • 34347213447 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation
    • Slape C., Hartung H., Lin Y.W., Bies J., Wolff L., Aplan P.D. Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation. Cancer Res 2007, 67:5148-5155.
    • (2007) Cancer Res , vol.67 , pp. 5148-5155
    • Slape, C.1    Hartung, H.2    Lin, Y.W.3    Bies, J.4    Wolff, L.5    Aplan, P.D.6
  • 34
    • 52649146276 scopus 로고    scopus 로고
    • Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl
    • Slape C., Liu L.Y., Beachy S., Aplan P.D. Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl. Blood 2008, 112:2017-2019.
    • (2008) Blood , vol.112 , pp. 2017-2019
    • Slape, C.1    Liu, L.Y.2    Beachy, S.3    Aplan, P.D.4
  • 35
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle
    • Nigg E.A. Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 1995, 17:471-480.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 36
    • 33750448971 scopus 로고    scopus 로고
    • UV irradiation induces a postreplication DNA damage checkpoint
    • Callegari A.J., Kelly T.J. UV irradiation induces a postreplication DNA damage checkpoint. Proc Natl Acad Sci U S A 2006, 103:15877-15882.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15877-15882
    • Callegari, A.J.1    Kelly, T.J.2
  • 37
    • 33749464522 scopus 로고    scopus 로고
    • A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress
    • Duensing A., Teng X., Liu Y., Tseng M., Spardy N., Duensing S. A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress. J Cell Biochem 2006, 99:759-769.
    • (2006) J Cell Biochem , vol.99 , pp. 759-769
    • Duensing, A.1    Teng, X.2    Liu, Y.3    Tseng, M.4    Spardy, N.5    Duensing, S.6
  • 38
    • 0032523011 scopus 로고    scopus 로고
    • Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression
    • Quesnel B., Guillerm G., Vereecque R., et al. Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression. Blood 1998, 91:2985-2990.
    • (1998) Blood , vol.91 , pp. 2985-2990
    • Quesnel, B.1    Guillerm, G.2    Vereecque, R.3
  • 39
    • 0030612423 scopus 로고    scopus 로고
    • Hypermethylation of the p15INK4B gene in myelodysplastic syndromes
    • Uchida T., Kinoshita T., Nagai H., et al. Hypermethylation of the p15INK4B gene in myelodysplastic syndromes. Blood 1997, 90:1403-1409.
    • (1997) Blood , vol.90 , pp. 1403-1409
    • Uchida, T.1    Kinoshita, T.2    Nagai, H.3
  • 40
    • 84872491877 scopus 로고    scopus 로고
    • ATM polymorphism is associated with low risk myelodysplastic syndrome
    • Ribeiro H.L., De Oliveira R.T., Maia A.R., et al. ATM polymorphism is associated with low risk myelodysplastic syndrome. DNA Repair (Amst) 2013, 12:87-89.
    • (2013) DNA Repair (Amst) , vol.12 , pp. 87-89
    • Ribeiro, H.L.1    De Oliveira, R.T.2    Maia, A.R.3
  • 41
    • 34247599335 scopus 로고    scopus 로고
    • A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification
    • Almeida K.H., Sobol R.W. A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) 2007, 6:695-711.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 695-711
    • Almeida, K.H.1    Sobol, R.W.2
  • 42
    • 0029784745 scopus 로고    scopus 로고
    • Replicative senescence, aging and growth-regulatory transcription factors
    • Dimri G.P., Testori A., Acosta M., Campisi J. Replicative senescence, aging and growth-regulatory transcription factors. Biol Signals 1996, 5:154-162.
    • (1996) Biol Signals , vol.5 , pp. 154-162
    • Dimri, G.P.1    Testori, A.2    Acosta, M.3    Campisi, J.4
  • 43
    • 33847673237 scopus 로고    scopus 로고
    • The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair
    • Hitomi K., Iwai S., Tainer J.A. The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. DNA Repair (Amst) 2007, 6:410-428.
    • (2007) DNA Repair (Amst) , vol.6 , pp. 410-428
    • Hitomi, K.1    Iwai, S.2    Tainer, J.A.3
  • 45
    • 56949091947 scopus 로고    scopus 로고
    • Oxidative DNA damage in bone marrow cells of patients with low-risk myelodysplastic syndrome
    • Novotna B., Bagryantseva Y., Siskova M., Neuwirtova R. Oxidative DNA damage in bone marrow cells of patients with low-risk myelodysplastic syndrome. Leuk Res 2009, 33:340-343.
    • (2009) Leuk Res , vol.33 , pp. 340-343
    • Novotna, B.1    Bagryantseva, Y.2    Siskova, M.3    Neuwirtova, R.4
  • 46
    • 0030664927 scopus 로고    scopus 로고
    • Oxidative DNA damage in CD34+ myelodysplastic cells is associated with intracellular redox changes and elevated plasma tumour necrosis factor-alpha concentration
    • Peddie C.M., Wolf C.R., McLellan L.I., Collins A.R., Bowen D.T. Oxidative DNA damage in CD34+ myelodysplastic cells is associated with intracellular redox changes and elevated plasma tumour necrosis factor-alpha concentration. Br J Haematol 1997, 99:625-631.
    • (1997) Br J Haematol , vol.99 , pp. 625-631
    • Peddie, C.M.1    Wolf, C.R.2    McLellan, L.I.3    Collins, A.R.4    Bowen, D.T.5
  • 47
    • 81955161844 scopus 로고    scopus 로고
    • DNA double-strand break repair pathways, chromosomal rearrangements and cancer
    • Kasparek T.R., Humphrey T.C. DNA double-strand break repair pathways, chromosomal rearrangements and cancer. Semin Cell Dev Biol 2011, 22:886-897.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 886-897
    • Kasparek, T.R.1    Humphrey, T.C.2
  • 48
    • 33747889722 scopus 로고    scopus 로고
    • Role of non-homologous end joining (NHEJ) in maintaining genomic integrity
    • Burma S., Chen B.P., Chen D.J. Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair (Amst) 2006, 5:1042-1048.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1042-1048
    • Burma, S.1    Chen, B.P.2    Chen, D.J.3
  • 49
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
    • McVey M., Lee S.E. MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings. Trends Genetics 2008, 24:529-538.
    • (2008) Trends Genetics , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 50
    • 37549065049 scopus 로고    scopus 로고
    • BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia
    • Omidvar N., Kogan S., Beurlet S., et al. BCL-2 and mutant NRAS interact physically and functionally in a mouse model of progressive myelodysplasia. Cancer Res 2007, 67:11657-11667.
    • (2007) Cancer Res , vol.67 , pp. 11657-11667
    • Omidvar, N.1    Kogan, S.2    Beurlet, S.3
  • 51
    • 34548789121 scopus 로고    scopus 로고
    • Reactive oxygen species, DNA damage, and error-prone repair: A model for genomic instability with progression in myeloid leukemia?
    • Rassool F.V., Gaymes T.J., Omidvar N., et al. Reactive oxygen species, DNA damage, and error-prone repair: A model for genomic instability with progression in myeloid leukemia?. Cancer Res 2007, 67:8762-8771.
    • (2007) Cancer Res , vol.67 , pp. 8762-8771
    • Rassool, F.V.1    Gaymes, T.J.2    Omidvar, N.3
  • 52
    • 84870861854 scopus 로고    scopus 로고
    • Non-homologous end joining mediated DNA repair is impaired in the NUP98-HOXD13 mouse model for myelodysplastic syndrome
    • Puthiyaveetil A.G., Reilly C.M., Pardee T.S., Caudell D.L. Non-homologous end joining mediated DNA repair is impaired in the NUP98-HOXD13 mouse model for myelodysplastic syndrome. Leuk Res 2013, 37:112-116.
    • (2013) Leuk Res , vol.37 , pp. 112-116
    • Puthiyaveetil, A.G.1    Reilly, C.M.2    Pardee, T.S.3    Caudell, D.L.4
  • 53
    • 84864012210 scopus 로고    scopus 로고
    • A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production
    • Puthiyaveetil A.G., Heid B., Reilly C.M., HogenEsch H., Caudell D.L. A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production. Exp Hematol 2012, 40:622-633.
    • (2012) Exp Hematol , vol.40 , pp. 622-633
    • Puthiyaveetil, A.G.1    Heid, B.2    Reilly, C.M.3    HogenEsch, H.4    Caudell, D.L.5
  • 55
    • 34548155765 scopus 로고    scopus 로고
    • The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients
    • Alemayehu A., Fridrichova I. The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients. Eur J Human Genet 2007, 15:922-929.
    • (2007) Eur J Human Genet , vol.15 , pp. 922-929
    • Alemayehu, A.1    Fridrichova, I.2
  • 56
    • 10544255085 scopus 로고    scopus 로고
    • Microsatellite instability and p53 mutations in therapy-related leukemia suggest mutator phenotype
    • Ben-Yehuda D., Krichevsky S., Caspi O., et al. Microsatellite instability and p53 mutations in therapy-related leukemia suggest mutator phenotype. Blood 1996, 88:4296-4303.
    • (1996) Blood , vol.88 , pp. 4296-4303
    • Ben-Yehuda, D.1    Krichevsky, S.2    Caspi, O.3
  • 57
    • 0242418183 scopus 로고    scopus 로고
    • Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome
    • Casorelli I., Offman J., Mele L., et al. Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome. DNA Repair (Amst) 2003, 2:547-559.
    • (2003) DNA Repair (Amst) , vol.2 , pp. 547-559
    • Casorelli, I.1    Offman, J.2    Mele, L.3
  • 58
    • 18444395238 scopus 로고    scopus 로고
    • Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia
    • Olipitz W., Hopfinger G., Aguiar R.C., et al. Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia. Genes Chromosomes Cancer 2002, 34:243-248.
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 243-248
    • Olipitz, W.1    Hopfinger, G.2    Aguiar, R.C.3
  • 59
    • 0041440074 scopus 로고    scopus 로고
    • Repopulating defect of mismatch repair-deficient hematopoietic stem cells
    • Reese J.S., Liu L., Gerson S.L. Repopulating defect of mismatch repair-deficient hematopoietic stem cells. Blood 2003, 102:1626-1633.
    • (2003) Blood , vol.102 , pp. 1626-1633
    • Reese, J.S.1    Liu, L.2    Gerson, S.L.3
  • 60
    • 84867706701 scopus 로고    scopus 로고
    • Nucleotide excision repair: new tricks with old bricks
    • Kamileri I., Karakasilioti I., Garinis G.A. Nucleotide excision repair: new tricks with old bricks. Trends Genetics 2012, 28:566-573.
    • (2012) Trends Genetics , vol.28 , pp. 566-573
    • Kamileri, I.1    Karakasilioti, I.2    Garinis, G.A.3
  • 61
    • 0036847904 scopus 로고    scopus 로고
    • Chromosomal instability and radiosensitivity in myelodysplastic syndrome cells
    • Kuramoto K., Ban S., Oda K., Tanaka H., Kimura A., Suzuki G. Chromosomal instability and radiosensitivity in myelodysplastic syndrome cells. Leukemia 2002, 16:2253-2258.
    • (2002) Leukemia , vol.16 , pp. 2253-2258
    • Kuramoto, K.1    Ban, S.2    Oda, K.3    Tanaka, H.4    Kimura, A.5    Suzuki, G.6
  • 62
    • 78650310294 scopus 로고    scopus 로고
    • Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy
    • Carney D.A., Westerman D.A., Tam C.S., et al. Therapy-related myelodysplastic syndrome and acute myeloid leukemia following fludarabine combination chemotherapy. Leukemia 2010, 24:2056-2062.
    • (2010) Leukemia , vol.24 , pp. 2056-2062
    • Carney, D.A.1    Westerman, D.A.2    Tam, C.S.3
  • 63
    • 33750958028 scopus 로고    scopus 로고
    • Treatment-related myelodysplasia following fludarabine combination chemotherapy
    • Tam C.S., Seymour J.F., Prince H.M., et al. Treatment-related myelodysplasia following fludarabine combination chemotherapy. Haematologica 2006, 91:1546-1550.
    • (2006) Haematologica , vol.91 , pp. 1546-1550
    • Tam, C.S.1    Seymour, J.F.2    Prince, H.M.3
  • 64
    • 0034551738 scopus 로고    scopus 로고
    • The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
    • Parker J.E., Mufti G.J., Rasool F., Mijovic A., Devereux S., Pagliuca A. The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS. Blood 2000, 96:3932-3938.
    • (2000) Blood , vol.96 , pp. 3932-3938
    • Parker, J.E.1    Mufti, G.J.2    Rasool, F.3    Mijovic, A.4    Devereux, S.5    Pagliuca, A.6
  • 65
    • 0037307728 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors
    • Tehranchi R., Fadeel B., Forsblom A.M., et al. Granulocyte colony-stimulating factor inhibits spontaneous cytochrome c release and mitochondria-dependent apoptosis of myelodysplastic syndrome hematopoietic progenitors. Blood 2003, 101:1080-1086.
    • (2003) Blood , vol.101 , pp. 1080-1086
    • Tehranchi, R.1    Fadeel, B.2    Forsblom, A.M.3
  • 66
    • 22044434111 scopus 로고    scopus 로고
    • Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes
    • Tehranchi R., Invernizzi R., Grandien A., et al. Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes. Blood 2005, 106:247-253.
    • (2005) Blood , vol.106 , pp. 247-253
    • Tehranchi, R.1    Invernizzi, R.2    Grandien, A.3
  • 67
    • 0036493359 scopus 로고    scopus 로고
    • Invitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis
    • Claessens Y.E., Bouscary D., Dupont J.M., et al. Invitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis. Blood 2002, 99:1594-1601.
    • (2002) Blood , vol.99 , pp. 1594-1601
    • Claessens, Y.E.1    Bouscary, D.2    Dupont, J.M.3
  • 68
    • 0032171391 scopus 로고    scopus 로고
    • Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression
    • Davis R.E., Greenberg P.L. Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression. Leuk Res 1998, 22:767-777.
    • (1998) Leuk Res , vol.22 , pp. 767-777
    • Davis, R.E.1    Greenberg, P.L.2
  • 69
    • 70350238389 scopus 로고    scopus 로고
    • Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes
    • Steensma D.P., Neiger J.D., Porcher J.C., et al. Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes. Cancer Res 2009, 69:7518-7523.
    • (2009) Cancer Res , vol.69 , pp. 7518-7523
    • Steensma, D.P.1    Neiger, J.D.2    Porcher, J.C.3
  • 70
    • 70349989871 scopus 로고    scopus 로고
    • Accelerated cellular senescence in myelodysplastic syndrome
    • Wang Y.Y., Cen J.N., He J., et al. Accelerated cellular senescence in myelodysplastic syndrome. Exp Hematol 2009, 37:1310-1317.
    • (2009) Exp Hematol , vol.37 , pp. 1310-1317
    • Wang, Y.Y.1    Cen, J.N.2    He, J.3
  • 71
    • 84863229585 scopus 로고    scopus 로고
    • A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
    • Wang J., Sun Q., Morita Y., et al. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell 2012, 148:1001-1014.
    • (2012) Cell , vol.148 , pp. 1001-1014
    • Wang, J.1    Sun, Q.2    Morita, Y.3
  • 72
    • 77956251480 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis
    • Mohrin M., Bourke E., Alexander D., et al. Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. Cell Stem Cell 2010, 7:174-185.
    • (2010) Cell Stem Cell , vol.7 , pp. 174-185
    • Mohrin, M.1    Bourke, E.2    Alexander, D.3
  • 73
    • 84863353872 scopus 로고    scopus 로고
    • A sensitive and quantitative polymerase chain reaction-based cell free invitro non-homologous end joining assay for hematopoietic stem cells
    • Shao L., Feng W., Lee K.J., Chen B.P., Zhou D. A sensitive and quantitative polymerase chain reaction-based cell free invitro non-homologous end joining assay for hematopoietic stem cells. PLoS One 2012, 7:e33499.
    • (2012) PLoS One , vol.7
    • Shao, L.1    Feng, W.2    Lee, K.J.3    Chen, B.P.4    Zhou, D.5
  • 74
    • 77956233247 scopus 로고    scopus 로고
    • A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal
    • Milyavsky M., Gan O.I., Trottier M., et al. A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal. Cell Stem Cell 2010, 7:186-197.
    • (2010) Cell Stem Cell , vol.7 , pp. 186-197
    • Milyavsky, M.1    Gan, O.I.2    Trottier, M.3
  • 75
    • 84863625900 scopus 로고    scopus 로고
    • Bone marrow failure in fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells
    • Ceccaldi R., Parmar K., Mouly E., et al. Bone marrow failure in fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell 2012, 11:36-49.
    • (2012) Cell Stem Cell , vol.11 , pp. 36-49
    • Ceccaldi, R.1    Parmar, K.2    Mouly, E.3
  • 76
    • 0036713424 scopus 로고    scopus 로고
    • Cancer predisposition and hematopoietic failure in Rad50(S/S) mice
    • Bender C.F., Sikes M.L., Sullivan R., et al. Cancer predisposition and hematopoietic failure in Rad50(S/S) mice. Genes Dev 2002, 16:2237-2251.
    • (2002) Genes Dev , vol.16 , pp. 2237-2251
    • Bender, C.F.1    Sikes, M.L.2    Sullivan, R.3
  • 77
    • 33846921755 scopus 로고    scopus 로고
    • The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging
    • Dumble M., Moore L., Chambers S.M., et al. The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood 2007, 109:1736-1742.
    • (2007) Blood , vol.109 , pp. 1736-1742
    • Dumble, M.1    Moore, L.2    Chambers, S.M.3
  • 78
    • 7244250309 scopus 로고    scopus 로고
    • Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
    • Ito K., Hirao A., Arai F., et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004, 431:997-1002.
    • (2004) Nature , vol.431 , pp. 997-1002
    • Ito, K.1    Hirao, A.2    Arai, F.3
  • 79
    • 42049085052 scopus 로고    scopus 로고
    • DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions
    • Morales M., Liu Y., Laiakis E.C., Morgan W.F., Nimer S.D., Petrini J.H. DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions. Cancer Res 2008, 68:2186-2193.
    • (2008) Cancer Res , vol.68 , pp. 2186-2193
    • Morales, M.1    Liu, Y.2    Laiakis, E.C.3    Morgan, W.F.4    Nimer, S.D.5    Petrini, J.H.6
  • 80
    • 0037711685 scopus 로고    scopus 로고
    • Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice
    • TeKippe M., Harrison D.E., Chen J. Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice. Exp Hematol 2003, 31:521-527.
    • (2003) Exp Hematol , vol.31 , pp. 521-527
    • TeKippe, M.1    Harrison, D.E.2    Chen, J.3
  • 81
    • 0037439151 scopus 로고    scopus 로고
    • Proapoptotic BID is required for myeloid homeostasis and tumor suppression
    • Zinkel S.S., Ong C.C., Ferguson D.O., et al. Proapoptotic BID is required for myeloid homeostasis and tumor suppression. Genes Dev 2003, 17:229-239.
    • (2003) Genes Dev , vol.17 , pp. 229-239
    • Zinkel, S.S.1    Ong, C.C.2    Ferguson, D.O.3
  • 83
    • 13344278020 scopus 로고    scopus 로고
    • Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia
    • Chen M., Tomkins D.J., Auerbach W., et al. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat Genet 1996, 12:448-451.
    • (1996) Nat Genet , vol.12 , pp. 448-451
    • Chen, M.1    Tomkins, D.J.2    Auerbach, W.3
  • 84
    • 0033168321 scopus 로고    scopus 로고
    • Loss of FancC function results in decreased hematopoietic stem cell repopulating ability
    • Haneline L.S., Gobbett T.A., Ramani R., et al. Loss of FancC function results in decreased hematopoietic stem cell repopulating ability. Blood 1999, 94:1-8.
    • (1999) Blood , vol.94 , pp. 1-8
    • Haneline, L.S.1    Gobbett, T.A.2    Ramani, R.3
  • 85
    • 61449106689 scopus 로고    scopus 로고
    • Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair
    • Lucas D., Escudero B., Ligos J.M., et al. Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair. PLoS Genet 2009, 5:e1000389.
    • (2009) PLoS Genet , vol.5
    • Lucas, D.1    Escudero, B.2    Ligos, J.M.3
  • 86
    • 33748043345 scopus 로고    scopus 로고
    • Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1
    • Navarro S., Meza N.W., Quintana-Bustamante O., et al. Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1. Mol Ther 2006, 14:525-535.
    • (2006) Mol Ther , vol.14 , pp. 525-535
    • Navarro, S.1    Meza, N.W.2    Quintana-Bustamante, O.3
  • 87
    • 34250001450 scopus 로고    scopus 로고
    • DNA repair is limiting for haematopoietic stem cells during ageing
    • Nijnik A., Woodbine L., Marchetti C., et al. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 2007, 447:686-690.
    • (2007) Nature , vol.447 , pp. 686-690
    • Nijnik, A.1    Woodbine, L.2    Marchetti, C.3
  • 88
    • 77954821842 scopus 로고    scopus 로고
    • Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1
    • Parmar K., Kim J., Sykes S.M., et al. Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1. Stem Cells 2010, 28:1186-1195.
    • (2010) Stem Cells , vol.28 , pp. 1186-1195
    • Parmar, K.1    Kim, J.2    Sykes, S.M.3
  • 89
    • 15444370725 scopus 로고    scopus 로고
    • Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice
    • Prasher J.M., Lalai A.S., Heijmans-Antonissen C., et al. Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice. EMBO J 2005, 24:861-871.
    • (2005) EMBO J , vol.24 , pp. 861-871
    • Prasher, J.M.1    Lalai, A.S.2    Heijmans-Antonissen, C.3
  • 90
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 91
    • 8944258558 scopus 로고    scopus 로고
    • Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene
    • Whitney M.A., Royle G., Low M.J., et al. Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene. Blood 1996, 88:49-58.
    • (1996) Blood , vol.88 , pp. 49-58
    • Whitney, M.A.1    Royle, G.2    Low, M.J.3
  • 92
    • 79955519714 scopus 로고    scopus 로고
    • Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair
    • Zhang S., Yajima H., Huynh H., et al. Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair. J Cell Biochem 2011, 193:295-305.
    • (2011) J Cell Biochem , vol.193 , pp. 295-305
    • Zhang, S.1    Yajima, H.2    Huynh, H.3
  • 93
    • 0032565509 scopus 로고    scopus 로고
    • Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair
    • Holmquist G.P. Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair. Mutat Res 1998, 400:59-68.
    • (1998) Mutat Res , vol.400 , pp. 59-68
    • Holmquist, G.P.1
  • 94
    • 33645730667 scopus 로고    scopus 로고
    • Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
    • Ito K., Hirao A., Arai F., et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 2006, 12:446-451.
    • (2006) Nat Med , vol.12 , pp. 446-451
    • Ito, K.1    Hirao, A.2    Arai, F.3
  • 95
    • 33846419112 scopus 로고    scopus 로고
    • FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
    • Tothova Z., Kollipara R., Huntly B.J., et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 2007, 128:325-339.
    • (2007) Cell , vol.128 , pp. 325-339
    • Tothova, Z.1    Kollipara, R.2    Huntly, B.J.3
  • 96
    • 0032938747 scopus 로고    scopus 로고
    • Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
    • Kurimasa A., Kumano S., Boubnov N.V., et al. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol Cell Biol 1999, 19:3877-3884.
    • (1999) Mol Cell Biol , vol.19 , pp. 3877-3884
    • Kurimasa, A.1    Kumano, S.2    Boubnov, N.V.3
  • 97
    • 79960343567 scopus 로고    scopus 로고
    • Regulation of endonuclease activity in human nucleotide excision repair
    • Fagbemi A.F., Orelli B., Scharer O.D. Regulation of endonuclease activity in human nucleotide excision repair. DNA Repair (Amst) 2011, 10:722-729.
    • (2011) DNA Repair (Amst) , vol.10 , pp. 722-729
    • Fagbemi, A.F.1    Orelli, B.2    Scharer, O.D.3
  • 98
    • 34547643762 scopus 로고    scopus 로고
    • Anemia in the elderly: How should we define it, when does it matter, and what can be done?
    • Steensma D.P., Tefferi A. Anemia in the elderly: How should we define it, when does it matter, and what can be done?. Mayo Clin Proc 2007, 82:958-966.
    • (2007) Mayo Clin Proc , vol.82 , pp. 958-966
    • Steensma, D.P.1    Tefferi, A.2
  • 99
    • 84880723626 scopus 로고    scopus 로고
    • Blood, bone marrow, and the lymphoid system
    • Elsevier-Saunders, Philadelphia, W. Schmidt, R. Gruliow (Eds.)
    • Damjanov I. Blood, bone marrow, and the lymphoid system. Pathophysiology 2009, 191-235. Elsevier-Saunders, Philadelphia. W. Schmidt, R. Gruliow (Eds.).
    • (2009) Pathophysiology , pp. 191-235
    • Damjanov, I.1
  • 100
    • 0031028973 scopus 로고    scopus 로고
    • Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity
    • de Haan G., Nijhof W., Van Zant G. Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity. Blood 1997, 89:1543-1550.
    • (1997) Blood , vol.89 , pp. 1543-1550
    • de Haan, G.1    Nijhof, W.2    Van Zant, G.3
  • 101
    • 0024380947 scopus 로고
    • Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age
    • Harrison D.E., Astle C.M., Stone M. Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age. J Immunol 1989, 142:3833-3840.
    • (1989) J Immunol , vol.142 , pp. 3833-3840
    • Harrison, D.E.1    Astle, C.M.2    Stone, M.3
  • 102
    • 12144278834 scopus 로고    scopus 로고
    • Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging
    • Kamminga L.M., van Os R., Ausema A., et al. Impaired hematopoietic stem cell functioning after serial transplantation and during normal aging. Stem Cells 2005, 23:82-92.
    • (2005) Stem Cells , vol.23 , pp. 82-92
    • Kamminga, L.M.1    van Os, R.2    Ausema, A.3
  • 104
    • 21544467270 scopus 로고    scopus 로고
    • Cell intrinsic alterations underlie hematopoietic stem cell aging
    • Rossi D.J., Bryder D., Zahn J.M., et al. Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A 2005, 102:9194-9199.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9194-9199
    • Rossi, D.J.1    Bryder, D.2    Zahn, J.M.3
  • 105
    • 0034613690 scopus 로고    scopus 로고
    • Age-associated characteristics of murine hematopoietic stem cells
    • Sudo K., Ema H., Morita Y., Nakauchi H. Age-associated characteristics of murine hematopoietic stem cells. J Exp Med 2000, 192:1273-1280.
    • (2000) J Exp Med , vol.192 , pp. 1273-1280
    • Sudo, K.1    Ema, H.2    Morita, Y.3    Nakauchi, H.4
  • 106
    • 79952338609 scopus 로고    scopus 로고
    • Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging
    • Rube C.E., Fricke A., Widmann T.A., et al. Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging. PLoS One 2011, 6:e17487.
    • (2011) PLoS One , vol.6
    • Rube, C.E.1    Fricke, A.2    Widmann, T.A.3
  • 107
    • 35848943273 scopus 로고    scopus 로고
    • Hematopoietic fingerprints: an expression database of stem cells and their progeny
    • Chambers S.M., Boles N.C., Lin K.Y., et al. Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell 2007, 1:578-591.
    • (2007) Cell Stem Cell , vol.1 , pp. 578-591
    • Chambers, S.M.1    Boles, N.C.2    Lin, K.Y.3
  • 108
    • 84866358168 scopus 로고    scopus 로고
    • The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
    • Bouwman P., Jonkers J. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance. Nat Rev Cancer 2012, 12:587-598.
    • (2012) Nat Rev Cancer , vol.12 , pp. 587-598
    • Bouwman, P.1    Jonkers, J.2


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