-
1
-
-
0029837329
-
Effect of thrombopoietin on the development of megakaryocytes and platelets: An ultrastructural analysis
-
Zucker-Franklin D, Kaushansky K: Effect of thrombopoietin on the development of megakaryocytes and platelets: An ultrastructural analysis. Blood 88:1632, 1996
-
(1996)
Blood
, vol.88
, pp. 1632
-
-
Zucker-Franklin, D.1
Kaushansky, K.2
-
2
-
-
0026684707
-
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily
-
Vigon I, Mornon JP, Cocault L, Mitjavila MT, Tambourin P, Gisselbrecht S, Souyri M: Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: Identification of a member of the hematopoietic growth factor receptor superfamily. Proc Natl Acad Sci USA 89:5640, 1992
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5640
-
-
Vigon, I.1
Mornon, J.P.2
Cocault, L.3
Mitjavila, M.T.4
Tambourin, P.5
Gisselbrecht, S.6
Souyri, M.7
-
3
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
De Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang WJ, Oles KJ, Hultgren B, Solberg Jr LA, Goeddel DV, Eaton DL: Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369:533, 1994
-
(1994)
Nature
, vol.369
, pp. 533
-
-
De Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.J.10
Oles, K.J.11
Hultgren, B.12
Solberg Jr., L.A.13
Goeddel, D.V.14
Eaton, D.L.15
-
4
-
-
0028332474
-
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin
-
Kaushansky K, Lok S, Holly RD, Broudy VC, Lin N, Balley MC, Forstrom JW, Buddle MM, Oort PJ, Hagen FS, Roth GJ, Papayannopoulou T, Foster DC: Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369: 568, 1994
-
(1994)
Nature
, vol.369
, pp. 568
-
-
Kaushansky, K.1
Lok, S.2
Holly, R.D.3
Broudy, V.C.4
Lin, N.5
Balley, M.C.6
Forstrom, J.W.7
Buddle, M.M.8
Oort, P.J.9
Hagen, F.S.10
Roth, G.J.11
Papayannopoulou, T.12
Foster, D.C.13
-
5
-
-
0028343099
-
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl
-
Bartley TD, Bogenberger J, Hunt P, Li YS, Lu HS, Martin F, Chnag MS, Samal B, Nichol JL, Swift S, Johnson MJ, Hsu RY, Parker VP, Suggs S, Skrine JD, Merewther LA, Clogston C, Hsu E, Hokom MM, Homkohl A, Choi E, Pangelinan M, Sun Y, Mar V, McNinch J, Simonet L, Jacbosen F, Xie C, Shutter J, Chute H, Basu R, Selander L, Trollinger D, Sieu L, Padilla D, Trail G, Elliott G, Izumi R, Covey T, Crouse J, Garcia A, Xu W, Del Castillo J, Biron J, Cole S, Hu MCT, Pacifici R, Ponting I, Saris C, Wen D, Yung YP, Lin H, Bosselman RA: Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77:1117, 1994
-
(1994)
Cell
, vol.77
, pp. 1117
-
-
Bartley, T.D.1
Bogenberger, J.2
Hunt, P.3
Li, Y.S.4
Lu, H.S.5
Martin, F.6
Chnag, M.S.7
Samal, B.8
Nichol, J.L.9
Swift, S.10
Johnson, M.J.11
Hsu, R.Y.12
Parker, V.P.13
Suggs, S.14
Skrine, J.D.15
Merewther, L.A.16
Clogston, C.17
Hsu, E.18
Hokom, M.M.19
Homkohl, A.20
Choi, E.21
Pangelinan, M.22
Sun, Y.23
Mar, V.24
McNinch, J.25
Simonet, L.26
Jacbosen, F.27
Xie, C.28
Shutter, J.29
Chute, H.30
Basu, R.31
Selander, L.32
Trollinger, D.33
Sieu, L.34
Padilla, D.35
Trail, G.36
Elliott, G.37
Izumi, R.38
Covey, T.39
Crouse, J.40
Garcia, A.41
Xu, W.42
Del Castillo, J.43
Biron, J.44
Cole, S.45
Hu, M.C.T.46
Pacifici, R.47
Ponting, I.48
Saris, C.49
Wen, D.50
Yung, Y.P.51
Lin, H.52
Bosselman, R.A.53
more..
-
6
-
-
0029037953
-
The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human magakaryocyte progenitors
-
Debili N, Wendling F, Katz A, Guichard J, Breton-Gorius J, Hunt P: The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human magakaryocyte progenitors. Blood 86:2516, 1995
-
(1995)
Blood
, vol.86
, pp. 2516
-
-
Debili, N.1
Wendling, F.2
Katz, A.3
Guichard, J.4
Breton-Gorius, J.5
Hunt, P.6
-
7
-
-
0032477741
-
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
-
Kimura S, Roberts AW, Metcalf D, Alexander WS: Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. Proc Natl Acad Sci USA 95:1195, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1195
-
-
Kimura, S.1
Roberts, A.W.2
Metcalf, D.3
Alexander, W.S.4
-
8
-
-
0032126638
-
Role of c-Mpl in early hematopoiesis
-
Solar GP, Kerr WG, Zeigler FC, Hess D, Donahue C, De Sauvage FJ, Eaton DL: Role of c-Mpl in early hematopoiesis. Blood 92:4, 1998
-
(1998)
Blood
, vol.92
, pp. 4
-
-
Solar, G.P.1
Kerr, W.G.2
Zeigler, F.C.3
Hess, D.4
Donahue, C.5
De Sauvage, F.J.6
Eaton, D.L.7
-
9
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG: Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966, 1994
-
(1994)
Science
, vol.265
, pp. 966
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Vande Woude, G.F.7
Ahn, N.G.8
-
10
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley S, Paterson H, Kemp P, Marshall CJ: Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77:841, 1994
-
(1994)
Cell
, vol.77
, pp. 841
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
11
-
-
0030160592
-
Control and integration of cell signaling pathways during C. elegans vulval development
-
Sundaram M, Han M: Control and integration of cell signaling pathways during C. elegans vulval development. Bioessays 18:473, 1996
-
(1996)
Bioessays
, vol.18
, pp. 473
-
-
Sundaram, M.1
Han, M.2
-
12
-
-
0028239896
-
The activities of two ets-related transcription factors required for drosophila eye development are modulated by the ras/MPK pathway
-
O'Neill EM, Rebay I, Tijian R, Rubin GM: The activities of two ets-related transcription factors required for drosophila eye development are modulated by the ras/MPK pathway. Cell 78:137, 1994
-
(1994)
Cell
, vol.78
, pp. 137
-
-
O'Neill, E.M.1
Rebay, I.2
Tijian, R.3
Rubin, G.M.4
-
13
-
-
0026486878
-
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells
-
Traverse S, Gomez N, Paterson H, Marshall C, Cohen P: Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Biochem J 288:351, 1992
-
(1992)
Biochem J
, vol.288
, pp. 351
-
-
Traverse, S.1
Gomez, N.2
Paterson, H.3
Marshall, C.4
Cohen, P.5
-
14
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila J, Forbush KA, Seger R, Krebs EG, Perlmutter RM: Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620, 1995
-
(1995)
Nature
, vol.373
, pp. 620
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
15
-
-
0030602798
-
The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
-
Crompton T, Gilmour KC, Owen MJ: The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86:243, 1996
-
(1996)
Cell
, vol.86
, pp. 243
-
-
Crompton, T.1
Gilmour, K.C.2
Owen, M.J.3
-
16
-
-
0030664126
-
Control of B cell development by Ras-mediated activation of Raf
-
Iritani BM, Forbush KA, Farrar MA, Perlmutter R: Control of B cell development by Ras-mediated activation of Raf. EMBO J 16:7019, 1997
-
(1997)
EMBO J
, vol.16
, pp. 7019
-
-
Iritani, B.M.1
Forbush, K.A.2
Farrar, M.A.3
Perlmutter, R.4
-
18
-
-
0023766145
-
Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
-
Sturgill TW, Ray LB, Erikson E, Maller JL: Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 334:715, 1988
-
(1988)
Nature
, vol.334
, pp. 715
-
-
Sturgill, T.W.1
Ray, L.B.2
Erikson, E.3
Maller, J.L.4
-
20
-
-
0032524356
-
Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
-
Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH: Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell 93:605, 1998
-
(1998)
Cell
, vol.93
, pp. 605
-
-
Khokhlatchev, A.V.1
Canagarajah, B.2
Wilsbacher, J.3
Robinson, M.4
Atkinson, M.5
Goldsmith, E.6
Cobb, M.H.7
-
21
-
-
0029935418
-
Regulation of transcription by MAP kinase cascade
-
Treisman R: Regulation of transcription by MAP kinase cascade. Curr Opin Cell Biol 8:205, 1996
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 205
-
-
Treisman, R.1
-
22
-
-
0029963565
-
Functional region of the mouse thrombopoietin receptor cytoplasmic domain: Evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin
-
Porteu F, Rouyez MC, Cocault L, Bénit L, Charon M, Picard F, Gisselbrecht S, Souyri M, Dusanter-Fourt I: Functional region of the mouse thrombopoietin receptor cytoplasmic domain: Evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin. Mol Cell Biol 16:2473, 1996
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2473
-
-
Porteu, F.1
Rouyez, M.C.2
Cocault, L.3
Bénit, L.4
Charon, M.5
Picard, F.6
Gisselbrecht, S.7
Souyri, M.8
Dusanter-Fourt, I.9
-
23
-
-
0029800869
-
Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation
-
Alexander WS, Maurer AB, Novak U, Harrison-Smith M: Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation. EMBO J 15:6531, 1996
-
(1996)
EMBO J
, vol.15
, pp. 6531
-
-
Alexander, W.S.1
Maurer, A.B.2
Novak, U.3
Harrison-Smith, M.4
-
24
-
-
0027433327
-
Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor
-
Fukunaga R, Ishizaka-Ikeda E, Nagata S: Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor. Cell 74:1079, 1993
-
(1993)
Cell
, vol.74
, pp. 1079
-
-
Fukunaga, R.1
Ishizaka-Ikeda, E.2
Nagata, S.3
-
25
-
-
0029885698
-
Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor
-
Ryan JJ, McReynolds U, Keegan A, Wang LH, Garfein E, Rothman P, Nelms K, Paul WE: Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor. Immunity 4:123, 1996
-
(1996)
Immunity
, vol.4
, pp. 123
-
-
Ryan, J.J.1
McReynolds, U.2
Keegan, A.3
Wang, L.H.4
Garfein, E.5
Rothman, P.6
Nelms, K.7
Paul, W.E.8
-
26
-
-
0029983731
-
The interleukin-7 receptor α chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis
-
Corcoran AE, Smart FM, Cowling RJ, Crompton T, Owen MJ, Venkitaraman AR: The interleukin-7 receptor α chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J 15:1924, 1996
-
(1996)
EMBO J
, vol.15
, pp. 1924
-
-
Corcoran, A.E.1
Smart, F.M.2
Cowling, R.J.3
Crompton, T.4
Owen, M.J.5
Venkitaraman, A.R.6
-
27
-
-
0032584680
-
Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor β chain (hβc) responsible for human GM-CSF-induced myeloid cell differentiation
-
Matsuguchi T, Lilly MB, Kraft AS: Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor β chain (hβc) responsible for human GM-CSF-induced myeloid cell differentiation. J Biol Chem 273:19411, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 19411
-
-
Matsuguchi, T.1
Lilly, M.B.2
Kraft, A.S.3
-
28
-
-
0029926755
-
Signaling by the cytokine receptor superfamily in normal and transformed hematopoietic cells
-
Ihle JN: Signaling by the cytokine receptor superfamily in normal and transformed hematopoietic cells. Adv Cancer Res 68:23, 1996
-
(1996)
Adv Cancer Res
, vol.68
, pp. 23
-
-
Ihle, J.N.1
-
29
-
-
0030871662
-
Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway
-
Rouyez MC, Boucheron C, Gisselbrecht S, Dusanter-Fourt I, Porteu F: Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway. Mol Cell Biol 17:4991, 1997
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4991
-
-
Rouyez, M.C.1
Boucheron, C.2
Gisselbrecht, S.3
Dusanter-Fourt, I.4
Porteu, F.5
-
30
-
-
0031000626
-
Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase
-
Whalen AM, Galasinski SC, Shapiro PS, Stines Nahreini T, Ahn NG: Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol Cell Biol 17:1947, 1997
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1947
-
-
Whalen, A.M.1
Galasinski, S.C.2
Shapiro, P.S.3
Stines Nahreini, T.4
Ahn, N.G.5
-
31
-
-
0030866934
-
Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells
-
Racke FK, Lewandowska K, Goueli S, Goldfarb AN: Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. J Biol Chem 272:23366, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 23366
-
-
Racke, F.K.1
Lewandowska, K.2
Goueli, S.3
Goldfarb, A.N.4
-
32
-
-
0030737420
-
Activation of the mitogen-activated protein kinase pathway is involved in and sufficient for megakaryocytic differentiation of CMK cells
-
Melemed AS, Ryder JW, Vik TA: Activation of the mitogen-activated protein kinase pathway is involved in and sufficient for megakaryocytic differentiation of CMK cells. Blood 90:3462, 1997
-
(1997)
Blood
, vol.90
, pp. 3462
-
-
Melemed, A.S.1
Ryder, J.W.2
Vik, T.A.3
-
33
-
-
0031028065
-
Thrombopoietin signal transduction in purified murine megakaryocytes
-
Drachman JG, Sabath DF, Fox NE, Kaushansky K: Thrombopoietin signal transduction in purified murine megakaryocytes. Blood 89:483, 1997
-
(1997)
Blood
, vol.89
, pp. 483
-
-
Drachman, J.G.1
Sabath, D.F.2
Fox, N.E.3
Kaushansky, K.4
-
34
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
Lin AW, Barradas M, Stone JC, Van Aelst L, Serrano M, Lowe SW: Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 12:3008, 1998
-
(1998)
Genes Dev
, vol.12
, pp. 3008
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
Van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
35
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR: A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7686
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
36
-
-
0031851630
-
High proliferative potential-quiescent cells: A working model to study primitive quiescent hematopoietic cells
-
Fortunel N, Batard P, Hatzfeld A, Monier MN, Panterne B, Lebkovski J, Hatzfeld J: High proliferative potential-quiescent cells: A working model to study primitive quiescent hematopoietic cells. J Cell Sci 111:1813, 1998
-
(1998)
J Cell Sci
, vol.111
, pp. 1813
-
-
Fortunel, N.1
Batard, P.2
Hatzfeld, A.3
Monier, M.N.4
Panterne, B.5
Lebkovski, J.6
Hatzfeld, J.7
-
37
-
-
0027103698
-
Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation
-
Debili N, Issaad C, Massé JM, Guichard J, Katz A, Breton-Gorius J, Vainchenker W: Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation. Blood 80:3022, 1992
-
(1992)
Blood
, vol.80
, pp. 3022
-
-
Debili, N.1
Issaad, C.2
Massé, J.M.3
Guichard, J.4
Katz, A.5
Breton-Gorius, J.6
Vainchenker, W.7
-
38
-
-
0029924148
-
+ cells are enriched for multipotent hematopoietic progenitors, but not for pluripotent stem cells
-
+ cells are enriched for multipotent hematopoietic progenitors, but not for pluripotent stem cells. Exp Hematol 24:236, 1996
-
(1996)
Exp Hematol
, vol.24
, pp. 236
-
-
Murray, L.J.1
Mandich, D.2
Bruno, E.3
DiGiusto, R.K.4
Fu, W.C.5
Sutherland, D.R.6
Hoffman, R.7
Tsukamoto, A.8
-
39
-
-
0030806320
-
Proliferation and differentiative potential of thrombopoietin-responsive precursors: Expression of megakaryocytic and erythroid lineage
-
Higuchi T, Koike K, Sawai N, Koike T: Proliferation and differentiative potential of thrombopoietin-responsive precursors: Expression of megakaryocytic and erythroid lineage. Exp Hematol 25:463, 1997
-
(1997)
Exp Hematol
, vol.25
, pp. 463
-
-
Higuchi, T.1
Koike, K.2
Sawai, N.3
Koike, T.4
-
40
-
-
0031802824
-
Effects of thrombopoietin on the proliferation and differentiation of primitive and mature haematopoietic progenitor cells in cord blood
-
Schipper LF, Brand A, Reniers NCM, Melief CJM, Willemze R, Fibbe WE: Effects of thrombopoietin on the proliferation and differentiation of primitive and mature haematopoietic progenitor cells in cord blood. Br J Haematol 101:425, 1998
-
(1998)
Br J Haematol
, vol.101
, pp. 425
-
-
Schipper, L.F.1
Brand, A.2
Reniers, N.C.M.3
Melief, C.J.M.4
Willemze, R.5
Fibbe, W.E.6
-
41
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR: PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270:27489, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 27489
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
42
-
-
0032582678
-
Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059
-
Börsch-Haubold A, Pasquet S, Watson SP: Direct inhibition of cyclooxygenase-1 and -2 by the kinase inhibitors SB 203580 and PD 98059. J Biol Chem 273:28766, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 28766
-
-
Börsch-Haubold, A.1
Pasquet, S.2
Watson, S.P.3
-
43
-
-
0033105851
-
The megakaryocyte/platelet-specific enhancer of the α2β1 integrin gene: Two tandem AP1 sites and the mitogen-activated protein kinase signaling cascade
-
Zutter MM, Painter AD, Yang X: The megakaryocyte/platelet-specific enhancer of the α2β1 integrin gene: Two tandem AP1 sites and the mitogen-activated protein kinase signaling cascade. Blood 93:1600, 1999
-
(1999)
Blood
, vol.93
, pp. 1600
-
-
Zutter, M.M.1
Painter, A.D.2
Yang, X.3
-
44
-
-
0031028381
-
Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway
-
Pumiglia KM, Decker SJ: Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. Proc Natl Acad Sci USA 94:448, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 448
-
-
Pumiglia, K.M.1
Decker, S.J.2
-
46
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh A, Rodriguez-Viciana P, Ulrich E, Gilbert C, Coffer P, Downward J, Evan G: Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385:544, 1997
-
(1997)
Nature
, vol.385
, pp. 544
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
47
-
-
0032521642
-
The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic
-
Tombes RM, Auer KL, Mikkelsen R, Valerie K, Wymann MP, Marshall CJ, McMahon M, Dent P: The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochem J 330:1451, 1998
-
(1998)
Biochem J
, vol.330
, pp. 1451
-
-
Tombes, R.M.1
Auer, K.L.2
Mikkelsen, R.3
Valerie, K.4
Wymann, M.P.5
Marshall, C.J.6
McMahon, M.7
Dent, P.8
-
48
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall CJ: Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179, 1995
-
(1995)
Cell
, vol.80
, pp. 179
-
-
Marshall, C.J.1
-
49
-
-
0029003672
-
Raf-1 protein is required for growth factor-induced proliferation of hematopoietic cells
-
Muszynski KW, Ruscetti FW, Heidecker G, Rapp U, Troppmair J, Gooya JM, Keller JR: Raf-1 protein is required for growth factor-induced proliferation of hematopoietic cells. J Exp Med 181:2189, 1995
-
(1995)
J Exp Med
, vol.181
, pp. 2189
-
-
Muszynski, K.W.1
Ruscetti, F.W.2
Heidecker, G.3
Rapp, U.4
Troppmair, J.5
Gooya, J.M.6
Keller, J.R.7
-
50
-
-
0032529283
-
Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis
-
Sui X, Krantz SB, You M, Zhao Z: Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis. Blood 92:1142, 1998
-
(1998)
Blood
, vol.92
, pp. 1142
-
-
Sui, X.1
Krantz, S.B.2
You, M.3
Zhao, Z.4
-
51
-
-
0032530921
-
Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation
-
Nagata Y, Takahashi N, Davis RJ, Todokoro K: Activation of p38 MAP kinase and JNK but not ERK is required for erythropoietin-induced erythroid differentiation. Blood 92:1859, 1998
-
(1998)
Blood
, vol.92
, pp. 1859
-
-
Nagata, Y.1
Takahashi, N.2
Davis, R.J.3
Todokoro, K.4
-
52
-
-
0029874495
-
The role of MAP kinase kinase in interleukin-3 stimulation of proliferation
-
Perkins GR, Marshall CJ, Collins MKL: The role of MAP kinase kinase in interleukin-3 stimulation of proliferation. Blood 87:3669, 1996
-
(1996)
Blood
, vol.87
, pp. 3669
-
-
Perkins, G.R.1
Marshall, C.J.2
Collins, M.K.L.3
-
53
-
-
0028837491
-
Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors
-
Kinoshita T, Yokota T, Arai KI, Miyajima A: Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J 14:266, 1995
-
(1995)
EMBO J
, vol.14
, pp. 266
-
-
Kinoshita, T.1
Yokota, T.2
Arai, K.I.3
Miyajima, A.4
-
54
-
-
0028876304
-
The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells
-
Gobert S, Duprez V, Lacombe C, Gisselbrecht S, Mayeux P: The signal transduction pathway of erythropoietin involves three forms of mitogen-activated protein (MAP) kinase in UT7 erythroleukemia cells. Eur J Biochem 234:75, 1995
-
(1995)
Eur J Biochem
, vol.234
, pp. 75
-
-
Gobert, S.1
Duprez, V.2
Lacombe, C.3
Gisselbrecht, S.4
Mayeux, P.5
-
55
-
-
0028864865
-
Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells
-
Mu SX, Xia M, Elliott G, Bogenberger J, Swift S, Bennett L, Lappinga DL, Hecht R, Lee R, Saris CJM: Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells. Blood 86:4532, 1995
-
(1995)
Blood
, vol.86
, pp. 4532
-
-
Mu, S.X.1
Xia, M.2
Elliott, G.3
Bogenberger, J.4
Swift, S.5
Bennett, L.6
Lappinga, D.L.7
Hecht, R.8
Lee, R.9
Saris, C.J.M.10
-
56
-
-
0029010473
-
Thrombopoietin activates a STAT5-like factor in hematopoietic cells
-
Pallard C, Gouilleux F, Bénit L, Cocault L, Souyri M, Levy D, Groner B, Gisselbrecht S, Dusanter-Fourt I: Thrombopoietin activates a STAT5-like factor in hematopoietic cells. EMBO J 14:2847, 1995
-
(1995)
EMBO J
, vol.14
, pp. 2847
-
-
Pallard, C.1
Gouilleux, F.2
Bénit, L.3
Cocault, L.4
Souyri, M.5
Levy, D.6
Groner, B.7
Gisselbrecht, S.8
Dusanter-Fourt, I.9
-
57
-
-
0028910991
-
The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl
-
Drachman JG, Griffin JD, Kaushansky K: The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl. J Biol Chem 270:4979, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 4979
-
-
Drachman, J.G.1
Griffin, J.D.2
Kaushansky, K.3
-
58
-
-
0030945261
-
Activation of JNK pathway by erythropoietin, thrombopoietin, and interleukin-3
-
Nagata Y, Nishida E, Todokoro K: Activation of JNK pathway by erythropoietin, thrombopoietin, and interleukin-3. Blood 89:2664, 1997
-
(1997)
Blood
, vol.89
, pp. 2664
-
-
Nagata, Y.1
Nishida, E.2
Todokoro, K.3
-
59
-
-
0029049709
-
Distinct regions of c-Mpl cyloplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
-
Gurney AL, Wong SC, Henzel WJ, De Sauvage FJ: Distinct regions of c-Mpl cyloplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. Proc Natl Acad Sci USA 92:5292, 1995
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5292
-
-
Gurney, A.L.1
Wong, S.C.2
Henzel, W.J.3
De Sauvage, F.J.4
-
60
-
-
0031806306
-
Involvement of prolonged Ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line
-
Matsumura I, Nakajima K, Wakao H, Hattori S, Hashimoto K, Sugahara H, Kato T, Miyazaki H, Hirano T, Kanakura Y: Involvement of prolonged Ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line. Mol Cell Biol 18:4282, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4282
-
-
Matsumura, I.1
Nakajima, K.2
Wakao, H.3
Hattori, S.4
Hashimoto, K.5
Sugahara, H.6
Kato, T.7
Miyazaki, H.8
Hirano, T.9
Kanakura, Y.10
-
61
-
-
0031433335
-
Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F
-
Brennan P, Babbage JW, Burgering BMT, Groner B, Reif K, Cantrell DA: Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Immunity 7:679, 1997
-
(1997)
Immunity
, vol.7
, pp. 679
-
-
Brennan, P.1
Babbage, J.W.2
Burgering, B.M.T.3
Groner, B.4
Reif, K.5
Cantrell, D.A.6
-
62
-
-
0029796643
-
Characterization of a bipotent erythromegakaryocytic progenitor in human bone marrow
-
Debili N, Coulombel L, Croisille L, Katz A, Guichard J, Breton-Gorius J, Vainchenker W: Characterization of a bipotent erythromegakaryocytic progenitor in human bone marrow. Blood 88:1284, 1996
-
(1996)
Blood
, vol.88
, pp. 1284
-
-
Debili, N.1
Coulombel, L.2
Croisille, L.3
Katz, A.4
Guichard, J.5
Breton-Gorius, J.6
Vainchenker, W.7
-
63
-
-
0031448222
-
The influence of the MAPK pathway on T cell lineage commitment
-
Sharp LL, Schwarz DA, Bott CM, Marshall CJ, Hedrick SM: The influence of the MAPK pathway on T cell lineage commitment. Immunity 7:609, 1997
-
(1997)
Immunity
, vol.7
, pp. 609
-
-
Sharp, L.L.1
Schwarz, D.A.2
Bott, C.M.3
Marshall, C.J.4
Hedrick, S.M.5
-
64
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill CS, Treisman R: Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80:199, 1995
-
(1995)
Cell
, vol.80
, pp. 199
-
-
Hill, C.S.1
Treisman, R.2
-
65
-
-
0029117304
-
Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation
-
Wen Z, Zhong Z, Darnell JE Jr: Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation. Cell 82:241, 1995
-
(1995)
Cell
, vol.82
, pp. 241
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
66
-
-
0032560514
-
Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation
-
Scheid MP, Duronio V: Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: Involvement of MEK upstream of Bad phosphorylation. Proc Natl Acad Sci USA 95:7439, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7439
-
-
Scheid, M.P.1
Duronio, V.2
|