A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: Implications for physiological and pathological megakaryocytic proliferation

PLoS Biology

Volumn 8, Issue 9, 2010, Pages

  Besancenot, Rodolphe ^a   Chaligné, Ronan ^a   Tonetti, Carole ^b   Pasquier, Florence ^a   Marty, Caroline ^a   Lécluse, Yann ^a   Vainchenker, William ^a   Constantinescu, Stefan N ^c   Giraudier, Stéphane ^a,b  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; EARLY GROWTH RESPONSE FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; THROMBOPOIETIN;

ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL LINE; CELL MATURATION; CELL PROLIFERATION; CELL STRAIN UT7 MPL; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MYELOFIBROSIS; MYELOPROLIFERATIVE DISORDER; NEOPLASM; PHYSIOLOGICAL PROCESS; POLYPLOIDY; SIGNAL TRANSDUCTION;

CELL AGING; CELL CYCLE; CELL LINE; CELL PROLIFERATION; HUMANS; MEGAKARYOCYTES; THROMBOPOIETIN;

EID: 77957896694     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1000476     Document Type: Article

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