메뉴 건너뛰기




Volumn 100, Issue 2, 2006, Pages 707-716

Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene

Author keywords

Apoptosis; Elevated blood pressure; Lymphoid cells

Indexed keywords

ADRENALIN; ALDOSTERONE; ANGIOTENSIN II; ARGININE; CORTICOSTERONE; CREATININE; CYCLIC AMP; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANYLATE CYCLASE; MESSENGER RNA; N(G) NITROARGININE; NITRIC ACID DERIVATIVE; NITRITE; NITROPRUSSIDE SODIUM; NORADRENALIN; POTASSIUM; PROSTAGLANDIN 6 KETO 1ALPHA; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; SODIUM; THROMBOXANE B2; UNCLASSIFIED DRUG;

EID: 33646366708     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00306.2005     Document Type: Article
Times cited : (25)

References (41)
  • 1
    • 0035804222 scopus 로고    scopus 로고
    • Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells
    • Arlt A, Grobe O, Sieke A, Kruse ML, Folsch UR, Schmidt WE, and Schafer H. Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells. Oncogene 20: 69-76, 2001.
    • (2001) Oncogene , vol.20 , pp. 69-76
    • Arlt, A.1    Grobe, O.2    Sieke, A.3    Kruse, M.L.4    Folsch, U.R.5    Schmidt, W.E.6    Schafer, H.7
  • 2
    • 0038282473 scopus 로고    scopus 로고
    • The early response gene IEX-1 attenuates NF-kappaB activation in 293 cells, a possible counter-regulatory process leading to enhanced cell death
    • Arlt A, Kruse ML, Breitenbroich M, Gehrz A, Koc B, Minkenberg J, Folsch UR, and Schafer H. The early response gene IEX-1 attenuates NF-kappaB activation in 293 cells, a possible counter-regulatory process leading to enhanced cell death. Oncogene 22: 3343-3351, 2003.
    • (2003) Oncogene , vol.22 , pp. 3343-3351
    • Arlt, A.1    Kruse, M.L.2    Breitenbroich, M.3    Gehrz, A.4    Koc, B.5    Minkenberg, J.6    Folsch, U.R.7    Schafer, H.8
  • 4
    • 0028124715 scopus 로고
    • Calcium signalling in T cells stimulated by a cyclophilin B-binding protein
    • Bram RJ and Crabtree GR. Calcium signalling in T cells stimulated by a cyclophilin B-binding protein. Nature 371: 355-358, 1994.
    • (1994) Nature , vol.371 , pp. 355-358
    • Bram, R.J.1    Crabtree, G.R.2
  • 5
    • 0028942436 scopus 로고
    • Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991
    • Burt VL, Whelton P, Roccella EJ, Brown C, Cutler JA, Higgins M, Horan MJ, and Labarthe D. Prevalence of hypertension in the US adult population. Results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension 25: 305-313, 1995.
    • (1995) Hypertension , vol.25 , pp. 305-313
    • Burt, V.L.1    Whelton, P.2    Roccella, E.J.3    Brown, C.4    Cutler, J.A.5    Higgins, M.6    Horan, M.J.7    Labarthe, D.8
  • 6
    • 0027481889 scopus 로고
    • Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein
    • Charles CH, Yoon JK, Simske JS, and Lau LF. Genomic structure, cDNA sequence, and expression of gly96, a growth factor-inducible immediate-early gene encoding a short-lived glycosylated protein. Oncogene 8: 797-801, 1993.
    • (1993) Oncogene , vol.8 , pp. 797-801
    • Charles, C.H.1    Yoon, J.K.2    Simske, J.S.3    Lau, L.F.4
  • 10
    • 0036790687 scopus 로고    scopus 로고
    • IEX-1: A new ERK substrate involved in both ERK survival activity and ERK activation
    • Garcia J, Ye Y, Arranz V, Letourneux C, Pezeron G, and Porteu F. IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation. EMBO J 21: 5151-5163, 2002.
    • (2002) EMBO J , vol.21 , pp. 5151-5163
    • Garcia, J.1    Ye, Y.2    Arranz, V.3    Letourneux, C.4    Pezeron, G.5    Porteu, F.6
  • 11
    • 0035853458 scopus 로고    scopus 로고
    • Functional disruption of IEX-1 expression by concatemeric hammerhead ribozymes alters growth properties of 293 cells
    • Grobe O, Arlt A, Ungefroren H, Krupp G, Folsch UR, Schmidt WE, and Schafer H. Functional disruption of IEX-1 expression by concatemeric hammerhead ribozymes alters growth properties of 293 cells. FEBS Lett 494: 196-200, 2001.
    • (2001) FEBS Lett , vol.494 , pp. 196-200
    • Grobe, O.1    Arlt, A.2    Ungefroren, H.3    Krupp, G.4    Folsch, U.R.5    Schmidt, W.E.6    Schafer, H.7
  • 12
    • 16844380140 scopus 로고    scopus 로고
    • Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of Ang II-mediated NFAT activation
    • Guo S, Lopez-Ilasaca M, and Dzau VJ. Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of Ang II-mediated NFAT activation. J Biol Chem 280: 12536-12541, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 12536-12541
    • Guo, S.1    Lopez-Ilasaca, M.2    Dzau, V.J.3
  • 13
    • 0242529076 scopus 로고    scopus 로고
    • Genetics
    • edited by Oparil S and Weber M. Philadelphia: Saunders
    • Harrap S. Genetics. In: Hypertension, edited by Oparil S and Weber M. Philadelphia: Saunders, 2000, p. 29-41.
    • (2000) Hypertension , pp. 29-41
    • Harrap, S.1
  • 14
    • 0029664622 scopus 로고    scopus 로고
    • 2+-modulating cyclophilin ligand modulates calcium influx signaling in T lymphocytes
    • 2+-modulating cyclophilin ligand modulates calcium influx signaling in T lymphocytes. J Biol Chem 271: 8549-8552, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 8549-8552
    • Holloway, M.P.1    Bram, R.J.2
  • 15
    • 0037161968 scopus 로고    scopus 로고
    • Characterization of a novel hexameric repeat DNA sequence in the promoter of the immediate early gene, IEX-1, that mediates 1alpha,25-dihydroxyvitamin D(3)-associated IEX-1 gene repression
    • Im HJ, Craig TA, Pittelkow MR, and Kumar R. Characterization of a novel hexameric repeat DNA sequence in the promoter of the immediate early gene, IEX-1, that mediates 1alpha,25-dihydroxyvitamin D(3)-associated IEX-1 gene repression. Oncogene 21: 3706-3714, 2002.
    • (2002) Oncogene , vol.21 , pp. 3706-3714
    • Im, H.J.1    Craig, T.A.2    Pittelkow, M.R.3    Kumar, R.4
  • 16
    • 0037177895 scopus 로고    scopus 로고
    • Divergent regulation of the growth-promoting gene IEX-1 by the p53 tumor suppressor and Sp1
    • Im HJ, Pittelkow MR, and Kumar R. Divergent regulation of the growth-promoting gene IEX-1 by the p53 tumor suppressor and Sp1. J Biol Chem 277: 14612-14621, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 14612-14621
    • Im, H.J.1    Pittelkow, M.R.2    Kumar, R.3
  • 18
    • 0032578848 scopus 로고    scopus 로고
    • Regulation of a novel immediate early response gene, IEX-1, in keratinocytes by 1alpha,25-dihydroxyvitamin D3
    • Kobayashi T, Pittelkow MR, Warner GM, Squillace KA, and Kumar R. Regulation of a novel immediate early response gene, IEX-1, in keratinocytes by 1alpha,25-dihydroxyvitamin D3. Biochem Biophys Res Commun 251: 868-873, 1998.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 868-873
    • Kobayashi, T.1    Pittelkow, M.R.2    Warner, G.M.3    Squillace, K.A.4    Kumar, R.5
  • 19
    • 0029965054 scopus 로고    scopus 로고
    • Identification and characterization of a radiation-inducible glycosylated human early-response gene
    • Kondratyev AD, Chung KN, and Jung MO. Identification and characterization of a radiation-inducible glycosylated human early-response gene. Cancer Res 56: 1498-1502, 1996.
    • (1996) Cancer Res , vol.56 , pp. 1498-1502
    • Kondratyev, A.D.1    Chung, K.N.2    Jung, M.O.3
  • 21
    • 4644278821 scopus 로고    scopus 로고
    • Immediate early gene X-1 interacts with proteins that modulate apoptosis
    • Kumar R, Lutz W, Frank E, and Im HJ. Immediate early gene X-1 interacts with proteins that modulate apoptosis. Biochem Biophys Res Commun 323: 1293-1298, 2004.
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 1293-1298
    • Kumar, R.1    Lutz, W.2    Frank, E.3    Im, H.J.4
  • 23
    • 0042328296 scopus 로고    scopus 로고
    • Functional genomics in rat models of hypertension: Using differential expression and congenic strains to identify and evaluate candidate genes
    • Lee SJ and Cicila GT. Functional genomics in rat models of hypertension: using differential expression and congenic strains to identify and evaluate candidate genes. Crit Rev Eukaryot Gene Expr 12: 297-316, 2002.
    • (2002) Crit Rev Eukaryot Gene Expr , vol.12 , pp. 297-316
    • Lee, S.J.1    Cicila, G.T.2
  • 24
    • 0347381133 scopus 로고    scopus 로고
    • All strain, no gain: Stretch keeps proliferation at bay via the NF-kappaB response gene iex-1
    • Lehoux S and Tedgui A. All strain, no gain: stretch keeps proliferation at bay via the NF-kappaB response gene iex-1. Circ Res 93: 1139-1141, 2003.
    • (2003) Circ Res , vol.93 , pp. 1139-1141
    • Lehoux, S.1    Tedgui, A.2
  • 25
    • 0026580019 scopus 로고
    • A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, and Lalouel JM. A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 355: 262-265, 1992.
    • (1992) Nature , vol.355 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Rich, G.M.4    Cook, S.5    Ulick, S.6    Lalouel, J.M.7
  • 26
    • 0036528839 scopus 로고    scopus 로고
    • Identification of mechanically induced genes in human monocytic cells by DNA microarrays
    • Ohki R, Yamamoto K, Mano H, Lee RT, Ikeda U, and Shimada K. Identification of mechanically induced genes in human monocytic cells by DNA microarrays. J Hypertens 20: 685-691, 2002.
    • (2002) J Hypertens , vol.20 , pp. 685-691
    • Ohki, R.1    Yamamoto, K.2    Mano, H.3    Lee, R.T.4    Ikeda, U.5    Shimada, K.6
  • 27
    • 0037446526 scopus 로고    scopus 로고
    • Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation
    • Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, and Nakashima S. Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation. J Immunol 170: 4053-4060, 2003.
    • (2003) J Immunol , vol.170 , pp. 4053-4060
    • Osawa, Y.1    Nagaki, M.2    Banno, Y.3    Brenner, D.A.4    Nozawa, Y.5    Moriwaki, H.6    Nakashima, S.7
  • 28
    • 0345019849 scopus 로고    scopus 로고
    • Genomic organization, promoter cloning, and chromosomal localization of the Dif-2 gene
    • Pietzsch A, Buchler C, and Schmitz G. Genomic organization, promoter cloning, and chromosomal localization of the Dif-2 gene. Biochem Biophys Res Commun 245: 651-657, 1998.
    • (1998) Biochem Biophys Res Commun , vol.245 , pp. 651-657
    • Pietzsch, A.1    Buchler, C.2    Schmitz, G.3
  • 29
    • 33646371554 scopus 로고    scopus 로고
    • Cardiac-specific gain-of-function mutation in the natriuretic peptide A receptor is associated with improved diastolic function
    • Pritchett A, Valencik M, McDonald J, Harders G, and Redfield M. Cardiac-specific gain-of-function mutation in the natriuretic peptide A receptor is associated with improved diastolic function (Abstract). J Card Fail 8: S6, 2002.
    • (2002) J Card Fail , vol.8
    • Pritchett, A.1    Valencik, M.2    McDonald, J.3    Harders, G.4    Redfield, M.5
  • 30
    • 5144231754 scopus 로고    scopus 로고
    • Immediate early response gene X-1, a stress-inducible antiapoptotic gene, encodes cytotoxic T-lymphocyte (CTL) epitopes capable of inducing human leukocyte antigen-A33-restricted and tumor-reactive CTLs in gastric cancer patients
    • Sasada T, Takedatsu H, Azuma K, Koga M, Maeda Y, Shichijo S, Shoumura H, Hirai T, Takabayashi A, and Itoh K. Immediate early response gene X-1, a stress-inducible antiapoptotic gene, encodes cytotoxic T-lymphocyte (CTL) epitopes capable of inducing human leukocyte antigen-A33-restricted and tumor-reactive CTLs in gastric cancer patients. Cancer Res 64: 2882-2888, 2004.
    • (2004) Cancer Res , vol.64 , pp. 2882-2888
    • Sasada, T.1    Takedatsu, H.2    Azuma, K.3    Koga, M.4    Maeda, Y.5    Shichijo, S.6    Shoumura, H.7    Hirai, T.8    Takabayashi, A.9    Itoh, K.10
  • 31
    • 0032475953 scopus 로고    scopus 로고
    • The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB
    • Schafer H, Diebel J, Arlt A, Trauzold A, and Schmidt WE. The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB. FEBS Lett 436: 139-143, 1998.
    • (1998) FEBS Lett , vol.436 , pp. 139-143
    • Schafer, H.1    Diebel, J.2    Arlt, A.3    Trauzold, A.4    Schmidt, W.E.5
  • 32
    • 0029999322 scopus 로고    scopus 로고
    • PRG1: A novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell line
    • Schafer H, Trauzold A, Siegel EG, Folsch UR, and Schmidt WE. PRG1: a novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell line. Cancer Res 56: 2641-2648, 1996.
    • (1996) Cancer Res , vol.56 , pp. 2641-2648
    • Schafer, H.1    Trauzold, A.2    Siegel, E.G.3    Folsch, U.R.4    Schmidt, W.E.5
  • 33
    • 0035969648 scopus 로고    scopus 로고
    • IEX-1, an immediate early gene, increases the rate of apoptosis in keratinocytes
    • Schilling D, Pittelkow MR, and Kumar R. IEX-1, an immediate early gene, increases the rate of apoptosis in keratinocytes. Oncogene 20: 7992-7997, 2001.
    • (2001) Oncogene , vol.20 , pp. 7992-7997
    • Schilling, D.1    Pittelkow, M.R.2    Kumar, R.3
  • 34
    • 0347252322 scopus 로고    scopus 로고
    • Biomechanically induced gene iex-1 inhibits vascular smooth muscle cell proliferation and neointima formation
    • Schulze PC, de Keulenaer GW, Kassik KA, Takahashi T, Chen Z, Simon DI, and Lee RT. Biomechanically induced gene iex-1 inhibits vascular smooth muscle cell proliferation and neointima formation. Circ Res 93: 1210-1217, 2003.
    • (2003) Circ Res , vol.93 , pp. 1210-1217
    • Schulze, P.C.1    De Keulenaer, G.W.2    Kassik, K.A.3    Takahashi, T.4    Chen, Z.5    Simon, D.I.6    Lee, R.T.7
  • 35
    • 1842866793 scopus 로고    scopus 로고
    • Gene targeting in mouse embryonic stem cells
    • edited by Hofker M and van Deursen J. Totowa, NJ: Humana
    • Van Deursen J. Gene targeting in mouse embryonic stem cells. In: Transgenic Mouse: Methods and Protocols. Methods in Molecular Biology, edited by Hofker M and van Deursen J. Totowa, NJ: Humana, 2003, p. 145-158.
    • (2003) Transgenic Mouse: Methods and Protocols. Methods in Molecular Biology , pp. 145-158
    • Van Deursen, J.1
  • 36
    • 0031840214 scopus 로고    scopus 로고
    • Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats
    • Vaziri ND, Ni Z, and Oveisi F. Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats. Hypertension 31: 1248-1254, 1998.
    • (1998) Hypertension , vol.31 , pp. 1248-1254
    • Vaziri, N.D.1    Ni, Z.2    Oveisi, F.3
  • 37
    • 0039792391 scopus 로고    scopus 로고
    • NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
    • Von Bulow GU and Bram RJ. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. Science 278: 138-141, 1997.
    • (1997) Science , vol.278 , pp. 138-141
    • Von Bulow, G.U.1    Bram, R.J.2
  • 38
    • 0037246194 scopus 로고    scopus 로고
    • Roles of the stress-induced gene IEX-1 in regulation of cell death and oncogenesis
    • Wu MX. Roles of the stress-induced gene IEX-1 in regulation of cell death and oncogenesis. Apoptosis 8: 11-18, 2003.
    • (2003) Apoptosis , vol.8 , pp. 11-18
    • Wu, M.X.1
  • 39
    • 0032516651 scopus 로고    scopus 로고
    • IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival
    • Wu MX, Ao Z, Prasad KV, Wu R, and Schlossman SF. IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science 281: 998-1001, 1998.
    • (1998) Science , vol.281 , pp. 998-1001
    • Wu, M.X.1    Ao, Z.2    Prasad, K.V.3    Wu, R.4    Schlossman, S.F.5
  • 41
    • 0037154253 scopus 로고    scopus 로고
    • Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
    • Zhang Y, Schlossman SF, Edwards RA, Ou CN, Gu J, and Wu MX. Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice. Proc Natl Acad Sci USA 99: 878-883, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 878-883
    • Zhang, Y.1    Schlossman, S.F.2    Edwards, R.A.3    Ou, C.N.4    Gu, J.5    Wu, M.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.