Thrombopoietin-increased DNA-PK-dependent DNA repair limits hematopoietic stem and progenitor cell mutagenesis in response to dna damage

Cell Stem Cell

Volumn 12, Issue 1, 2013, Pages 37-48

  De Laval, Bérengère ^a,b,c   Pawlikowska, Patrycja ^a,b,c   Petit Cocault, Laurence ^d   Bilhou Nabera, Chrystèle ^e   Aubin Houzelstein, Geneviève ^f   Souyri, Michèle ^d   Pouzoulet, Frédéric ^g   Gaudry, Murielle ^a,b,c   Porteu, Françoise ^a,b,c  

^a INSTITUT COCHIN   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Université René Descartes   (France)

^e HÔPITAL SAINT ANTOINE   (France)

^f ECOLE NATIONALE VÉTÉRINAIRE D ALFORT   (France)

^g INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; DNA DEPENDENT PROTEIN KINASE; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; GAMMA IRRADIATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION INJURY; RADIATION MUTAGENESIS; RADIATION RESPONSE; REGULATORY MECHANISM; STEM CELL NICHE; WILD TYPE;

ANIMALS; CELL CYCLE; COMET ASSAY; DNA DAMAGE; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTAGENESIS; STEM CELLS; THROMBOPOIETIN;

EID: 84872047504     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.10.012     Document Type: Article

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