-
1
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Epub 2009/07/18
-
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC et al (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325(5942):834-840, Epub 2009/07/18.
-
(2009)
Science
, vol.325
, Issue.5942
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
-
2
-
-
84869880178
-
Histone deacetylases and cancer
-
Epub 2012/09/12
-
Barneda-Zahonero B, Parra M (2012) Histone deacetylases and cancer. Mol Oncol 6(6):579-589, Epub 2012/09/12.
-
(2012)
Mol Oncol
, vol.6
, Issue.6
, pp. 579-589
-
-
Barneda-Zahonero, B.1
Parra, M.2
-
3
-
-
77955686258
-
Regulatory signal transduction pathways for class IIa histone deacetylases
-
Epub 2010/05/08
-
Parra M, Verdin E (2010) Regulatory signal transduction pathways for class IIa histone deacetylases. Curr Opin Pharmacol 10(4):454-460, Epub 2010/05/08.
-
(2010)
Curr Opin Pharmacol
, vol.10
, Issue.4
, pp. 454-460
-
-
Parra, M.1
Verdin, E.2
-
4
-
-
33646354640
-
A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition
-
Epub 2006/04/28
-
Ropero S, Fraga MF, Ballestar E, Hamelin R, Yamamoto H, Boix-Chornet M et al (2006) A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition. Nat Genet 38(5):566-569, Epub 2006/04/28.
-
(2006)
Nat Genet
, vol.38
, Issue.5
, pp. 566-569
-
-
Ropero, S.1
Fraga, M.F.2
Ballestar, E.3
Hamelin, R.4
Yamamoto, H.5
Boix-Chornet, M.6
-
5
-
-
84867783133
-
Mechanisms of resistance to histone deacetylase inhibitors
-
Epub 2012/10/24
-
Lee JH, Choy ML, Marks PA (2012) Mechanisms of resistance to histone deacetylase inhibitors. Adv Cancer Res 116:39-86, Epub 2012/10/24.
-
(2012)
Adv Cancer Res
, vol.116
, pp. 39-86
-
-
Lee, J.H.1
Choy, M.L.2
Marks, P.A.3
-
6
-
-
80054720150
-
The biology of HDAC in cancer: The nuclear and epigenetic components
-
Epub 2011/09/01
-
Hagelkruys A, Sawicka A, Rennmayr M, Seiser C (2011) The biology of HDAC in cancer: the nuclear and epigenetic components. Handb Exp Pharmacol 206:13-37, Epub 2011/09/01.
-
(2011)
Handb Exp Pharmacol
, vol.206
, pp. 13-37
-
-
Hagelkruys, A.1
Sawicka, A.2
Rennmayr, M.3
Seiser, C.4
-
7
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Epub 1998/02/19
-
Magnaghi-Jaulin L, Groisman R, Naguibneva I, Robin P, Lorain S, Le Villain JP et al (1998) Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391(6667):601-605, Epub 1998/02/19.
-
(1998)
Nature
, vol.391
, Issue.6667
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
Le Villain, J.P.6
-
8
-
-
84865479772
-
Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells
-
e1-15. Epub 2012/05/30
-
Buurman R, Gurlevik E, Schaffer V, Eilers M, Sandbothe M, Kreipe H et al (2012) Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells. Gastroenterology 143(3):811-820, e1-15. Epub 2012/05/30.
-
(2012)
Gastroenterology
, vol.143
, Issue.3
, pp. 811-820
-
-
Buurman, R.1
Gurlevik, E.2
Schaffer, V.3
Eilers, M.4
Sandbothe, M.5
Kreipe, H.6
-
9
-
-
84855471990
-
HDAC inhibitors in cancer biology: Emerging mechanisms and clinical applications
-
Epub 2011/11/30
-
Khan O, La Thangue NB (2012) HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol Cell Biol 90(1):85-94, Epub 2011/11/30.
-
(2012)
Immunol Cell Biol
, vol.90
, Issue.1
, pp. 85-94
-
-
Khan, O.1
la Thangue, N.B.2
-
10
-
-
84876719154
-
Immunomodulatory effects of histone deacetylase inhibitors
-
Epub 2012/10/16
-
Licciardi PV, Ververis K, Tang ML, El-Osta A, Karagiannis TC (2012) Immunomodulatory effects of histone deacetylase inhibitors. Curr Mol Med 13(4):640-647, Epub 2012/10/16.
-
(2012)
Curr Mol Med
, vol.13
, Issue.4
, pp. 640-647
-
-
Licciardi, P.V.1
Ververis, K.2
Tang, M.L.3
El-Osta, A.4
Karagiannis, T.C.5
-
11
-
-
59449087016
-
Histone modifying enzymes: Structures, mechanisms, and specificities
-
Epub 2008/08/30
-
Marmorstein R, Trievel RC (2009) Histone modifying enzymes: structures, mechanisms, and specificities. Biochim Biophys Acta 1789(1):58-68, Epub 2008/08/30.
-
(2009)
Biochim Biophys Acta
, vol.1789
, Issue.1
, pp. 58-68
-
-
Marmorstein, R.1
Trievel, R.C.2
-
12
-
-
80053609229
-
HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly
-
Epub 2011/10/11
-
Yang X, Yu W, Shi L, Sun L, Liang J, Yi X et al (2011) HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly. Mol Cell 44(1):39-50, Epub 2011/10/11.
-
(2011)
Mol Cell
, vol.44
, Issue.1
, pp. 39-50
-
-
Yang, X.1
Yu, W.2
Shi, L.3
Sun, L.4
Liang, J.5
Yi, X.6
-
13
-
-
34547896549
-
The MYST family of histone acetyltransferases and their intimate links to cancer
-
Epub 2007/08/19
-
Avvakumov N, Cote J (2007) The MYST family of histone acetyltransferases and their intimate links to cancer. Oncogene 26(37):5395-5407, Epub 2007/08/19.
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5395-5407
-
-
Avvakumov, N.1
Cote, J.2
-
14
-
-
0034654011
-
Acetylation: A regulatory modification to rival phosphorylation?
-
Epub 2000/03/16
-
Kouzarides T (2000) Acetylation: a regulatory modification to rival phosphorylation? EMBO J 19(6):1176-1179, Epub 2000/03/16.
-
(2000)
EMBO J
, vol.19
, Issue.6
, pp. 1176-1179
-
-
Kouzarides, T.1
-
15
-
-
84867724868
-
Discovery and characterization of NK13650s, naturally occurring p300-selective histone acetyltransferase inhibitors
-
Epub 2012/09/19
-
Tohyama S, Tomura A, Ikeda N, Hatano M, Odanaka J, Kubota Y et al (2012) Discovery and characterization of NK13650s, naturally occurring p300-selective histone acetyltransferase inhibitors. J Org Chem 77(20):9044-9052, Epub 2012/09/19.
-
(2012)
J Org Chem
, vol.77
, Issue.20
, pp. 9044-9052
-
-
Tohyama, S.1
Tomura, A.2
Ikeda, N.3
Hatano, M.4
Odanaka, J.5
Kubota, Y.6
-
16
-
-
84859181036
-
Histone recognition and large-scale structural analysis of the human bromodomain family
-
Epub 2012/04/03
-
Filippakopoulos P, Picaud S, Mangos M, Keates T, Lambert JP, Barsyte-Lovejoy D et al (2012) Histone recognition and large-scale structural analysis of the human bromodomain family. Cell 149(1):214-231, Epub 2012/04/03.
-
(2012)
Cell
, vol.149
, Issue.1
, pp. 214-231
-
-
Filippakopoulos, P.1
Picaud, S.2
Mangos, M.3
Keates, T.4
Lambert, J.P.5
Barsyte-Lovejoy, D.6
-
17
-
-
0026608175
-
The bromodomain: A conserved sequence found in human, Drosophila and yeast proteins
-
Epub 1992/05/25
-
Haynes SR, Dollard C, Winston F, Beck S, Trowsdale J, Dawid IB (1992) The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res 20(10):2603, Epub 1992/05/25.
-
(1992)
Nucleic Acids Res
, vol.20
, Issue.10
, pp. 2603
-
-
Haynes, S.R.1
Dollard, C.2
Winston, F.3
Beck, S.4
Trowsdale, J.5
Dawid, I.B.6
-
19
-
-
84870495530
-
Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
-
Epub 2012/10/04
-
Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, Haverty PM et al (2012) Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Res 22(12):2315-2327, Epub 2012/10/04.
-
(2012)
Genome Res
, vol.22
, Issue.12
, pp. 2315-2327
-
-
Liu, J.1
Lee, W.2
Jiang, Z.3
Chen, Z.4
Jhunjhunwala, S.5
Haverty, P.M.6
-
20
-
-
78549291781
-
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2
-
Epub 2010/09/25
-
Kalashnikova EV, Revenko AS, Gemo AT, Andrews NP, Tepper CG, Zou JX et al (2010) ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2. Cancer Res 70(22):9402-9412, Epub 2010/09/25.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9402-9412
-
-
Kalashnikova, E.V.1
Revenko, A.S.2
Gemo, A.T.3
Andrews, N.P.4
Tepper, C.G.5
Zou, J.X.6
-
21
-
-
36749066161
-
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification
-
Epub 2007/11/14
-
Zou JX, Revenko AS, Li LB, Gemo AT, Chen HW (2007) ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification. Proc Natl Acad Sci USA 104(46):18067-18072, Epub 2007/11/14.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.46
, pp. 18067-18072
-
-
Zou, J.X.1
Revenko, A.S.2
Li, L.B.3
Gemo, A.T.4
Chen, H.W.5
-
22
-
-
84875214218
-
Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex
-
Epub 2012/10/06
-
Duan Z, Zou JX, Yang P, Wang Y, Borowsky AD, Gao AC et al (2012) Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex. Prostate 73(5):455-466, Epub 2012/10/06.
-
(2012)
Prostate
, vol.73
, Issue.5
, pp. 455-466
-
-
Duan, Z.1
Zou, J.X.2
Yang, P.3
Wang, Y.4
Borowsky, A.D.5
Gao, A.C.6
-
23
-
-
84867496646
-
A comparative and integrative approach identifies ATPase family, AAA domain containing 2 as a likely driver of cell proliferation in lung adenocarcinoma
-
Epub 2012/08/24
-
Fouret R, Laffaire J, Hofman P, Beau-Faller M, Mazieres J, Validire P et al (2012) A comparative and integrative approach identifies ATPase family, AAA domain containing 2 as a likely driver of cell proliferation in lung adenocarcinoma. Clin Cancer Res 18(20):5606- 5616, Epub 2012/08/24.
-
(2012)
Clin Cancer Res 18(20):5606-
, pp. 5616
-
-
Fouret, R.1
Laffaire, J.2
Hofman, P.3
Beau-Faller, M.4
Mazieres, J.5
Validire, P.6
-
24
-
-
78650212982
-
ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis
-
Epub 2010/12/17
-
Leachman NT, Brellier F, Ferralli J, Chiquet-Ehrismann R, Tucker RP (2010) ATAD2B is a phylogenetically conserved nuclear protein expressed during neuronal differentiation and tumorigenesis. Dev Growth Differ 52(9):747-755, Epub 2010/12/17.
-
(2010)
Dev Growth Differ
, vol.52
, Issue.9
, pp. 747-755
-
-
Leachman, N.T.1
Brellier, F.2
Ferralli, J.3
Chiquet-Ehrismann, R.4
Tucker, R.P.5
-
25
-
-
78649541407
-
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
-
Epub 2010/09/22
-
Revenko AS, Kalashnikova EV, Gemo AT, Zou JX, Chen HW (2010) Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Mol Cell Biol 30(22):5260-5272, Epub 2010/09/22.
-
(2010)
Mol Cell Biol
, vol.30
, Issue.22
, pp. 5260-5272
-
-
Revenko, A.S.1
Kalashnikova, E.V.2
Gemo, A.T.3
Zou, J.X.4
Chen, H.W.5
-
26
-
-
84862511427
-
Comparative kinome analysis to identify putative colon tumor biomarkers
-
Epub 2011/11/19
-
Hennig EE, Mikula M, Rubel T, Dadlez M, Ostrowski J (2012) Comparative kinome analysis to identify putative colon tumor biomarkers. J Mol Med (Berl) 90(4):447-456, Epub 2011/11/19.
-
(2012)
J Mol Med (Berl)
, vol.90
, Issue.4
, pp. 447-456
-
-
Hennig, E.E.1
Mikula, M.2
Rubel, T.3
Dadlez, M.4
Ostrowski, J.5
-
27
-
-
33645457574
-
Fusion of ETV6 with an intronic sequence of the BAZ2A gene in a paediatric pre-B acute lymphoblastic leukaemia with a cryptic chromosome 12 rearrangement
-
Epub 2006/04/29
-
Panagopoulos I, Strombeck B, Isaksson M, Heldrup J, Olofsson T, Johansson B (2006) Fusion of ETV6 with an intronic sequence of the BAZ2A gene in a paediatric pre-B acute lymphoblastic leukaemia with a cryptic chromosome 12 rearrangement. Br J Haematol 133(3):270-275, Epub 2006/04/29.
-
(2006)
Br J Haematol
, vol.133
, Issue.3
, pp. 270-275
-
-
Panagopoulos, I.1
Strombeck, B.2
Isaksson, M.3
Heldrup, J.4
Olofsson, T.5
Johansson, B.6
-
28
-
-
58249118804
-
Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia
-
Epub 2008/11/21
-
Nebral K, Denk D, Attarbaschi A, Konig M, Mann G, Haas OA et al (2009) Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia. Leukemia 23(1):134-143, Epub 2008/11/21.
-
(2009)
Leukemia
, vol.23
, Issue.1
, pp. 134-143
-
-
Nebral, K.1
Denk, D.2
Attarbaschi, A.3
Konig, M.4
Mann, G.5
Haas, O.A.6
-
29
-
-
27144433485
-
Brd2/ RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1
-
Epub 2005/10/18
-
Viejo-Borbolla A, Ottinger M, Bruning E, Burger A, Konig R, Kati E et al (2005) Brd2/ RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1. J Virol 79(21):13618-13629, Epub 2005/10/18.
-
(2005)
J Virol
, vol.79
, Issue.21
, pp. 13618-13629
-
-
Viejo-Borbolla, A.1
Ottinger, M.2
Bruning, E.3
Burger, A.4
Konig, R.5
Kati, E.6
-
30
-
-
0042853421
-
Expression of BRD7- interacting proteins, BRD2 and BRD3, in nasopharyngeal carcinoma tissues
-
Zhou M, Peng C, Nie XM, Zhang BC, Zhu SG, Yu Y et al (2003) Expression of BRD7- interacting proteins, BRD2 and BRD3, in nasopharyngeal carcinoma tissues. Chin J Cancer 22(2):123-127.
-
(2003)
Chin J Cancer
, vol.22
, Issue.2
, pp. 123-127
-
-
Zhou, M.1
Peng, C.2
Nie, X.M.3
Zhang, B.C.4
Zhu, S.G.5
Yu, Y.6
-
31
-
-
41649120757
-
BRD-NUT oncoproteins: A family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells
-
Epub 2007/10/16
-
French CA, Ramirez CL, Kolmakova J, Hickman TT, Cameron MJ, Thyne ME et al (2008) BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells. Oncogene 27(15):2237-2242, Epub 2007/10/16.
-
(2008)
Oncogene
, vol.27
, Issue.15
, pp. 2237-2242
-
-
French, C.A.1
Ramirez, C.L.2
Kolmakova, J.3
Hickman, T.T.4
Cameron, M.J.5
Thyne, M.E.6
-
32
-
-
80054984945
-
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
-
Epub 2011/10/04
-
Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI et al (2011) Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 478(7370):529-533, Epub 2011/10/04.
-
(2011)
Nature
, vol.478
, Issue.7370
, pp. 529-533
-
-
Dawson, M.A.1
Prinjha, R.K.2
Dittmann, A.3
Giotopoulos, G.4
Bantscheff, M.5
Chan, W.I.6
-
33
-
-
84856857218
-
Pathogenesis of NUT midline carcinoma
-
Epub 2011/10/25
-
French CA (2012) Pathogenesis of NUT midline carcinoma. Annu Rev Pathol 7:247-265, Epub 2011/10/25.
-
(2012)
Annu Rev Pathol
, vol.7
, pp. 247-265
-
-
French, C.A.1
-
34
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Epub 2011/09/06
-
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM et al (2011) BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146(6):904-917, Epub 2011/09/06.
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
Jacobs, H.M.6
-
35
-
-
84869753078
-
Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
-
Epub 2012/11/07
-
Lockwood WW, Zejnullahu K, Bradner JE, Varmus H (2012) Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins. Proc Natl Acad Sci USA 109(47):19408-19413, Epub 2012/11/07.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.47
, pp. 19408-19413
-
-
Lockwood, W.W.1
Zejnullahu, K.2
Bradner, J.E.3
Varmus, H.4
-
36
-
-
33748484257
-
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes
-
Epub 2006/08/31
-
You J, Srinivasan V, Denis GV, Harrington WJ Jr, Ballestas ME, Kaye KM et al (2006) Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes. J Virol 80(18):8909-8919, Epub 2006/08/31.
-
(2006)
J Virol
, vol.80
, Issue.18
, pp. 8909-8919
-
-
You, J.1
Srinivasan, V.2
Denis, G.V.3
Harrington Jr., W.J.4
Ballestas, M.E.5
Kaye, K.M.6
-
37
-
-
33646423566
-
Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer
-
Epub 2005/12/15
-
Grunwald C, Koslowski M, Arsiray T, Dhaene K, Praet M, Victor A et al (2006) Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer. Int J Cancer 118(10):2522-2528, Epub 2005/12/15.
-
(2006)
Int J Cancer
, vol.118
, Issue.10
, pp. 2522-2528
-
-
Grunwald, C.1
Koslowski, M.2
Arsiray, T.3
Dhaene, K.4
Praet, M.5
Victor, A.6
-
38
-
-
77950517628
-
BRD7 is a candidate tumour suppressor gene required for p53 function
-
Epub 2010/03/17
-
Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H et al (2010) BRD7 is a candidate tumour suppressor gene required for p53 function. Nat Cell Biol 12(4):380-389, Epub 2010/03/17.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.4
, pp. 380-389
-
-
Drost, J.1
Mantovani, F.2
Tocco, F.3
Elkon, R.4
Comel, A.5
Holstege, H.6
-
39
-
-
70449581225
-
BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy
-
Epub 2009/09/30
-
Yamada HY, Rao CV (2009) BRD8 is a potential chemosensitizing target for spindle poisons in colorectal cancer therapy. Int J Oncol 35(5):1101-1109, Epub 2009/09/30.
-
(2009)
Int J Oncol
, vol.35
, Issue.5
, pp. 1101-1109
-
-
Yamada, H.Y.1
Rao, C.V.2
-
40
-
-
40049087659
-
Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
-
Epub 2008/03/11
-
Kang JU, Koo SH, Kwon KC, Park JW, Kim JM (2008) Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet Cytogenet 182(1):1-11, Epub 2008/03/11.
-
(2008)
Cancer Genet Cytogenet
, vol.182
, Issue.1
, pp. 1-11
-
-
Kang, J.U.1
Koo, S.H.2
Kwon, K.C.3
Park, J.W.4
Kim, J.M.5
-
41
-
-
46749101032
-
The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity
-
Epub 2008/05/13
-
Laue K, Daujat S, Crump JG, Plaster N, Roehl HH, Kimmel CB et al (2008) The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity. Development 135(11):1935-1946, Epub 2008/05/13.
-
(2008)
Development
, vol.135
, Issue.11
, pp. 1935-1946
-
-
Laue, K.1
Daujat, S.2
Crump, J.G.3
Plaster, N.4
Roehl, H.H.5
Kimmel, C.B.6
-
42
-
-
55849149371
-
Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes
-
Epub 2008/09/17
-
Ullah M, Pelletier N, Xiao L, Zhao SP, Wang K, Degerny C et al (2008) Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes. Mol Cell Biol 28(22):6828-6843, Epub 2008/09/17.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.22
, pp. 6828-6843
-
-
Ullah, M.1
Pelletier, N.2
Xiao, L.3
Zhao, S.P.4
Wang, K.5
Degerny, C.6
-
43
-
-
11844265853
-
Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes
-
Epub 2004/11/16
-
Kalla C, Nentwich H, Schlotter M, Mertens D, Wildenberger K, Dohner H et al (2005) Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes. Genes Chromosomes Cancer 42(2):128-143, Epub 2004/11/16.
-
(2005)
Genes Chromosomes Cancer
, vol.42
, Issue.2
, pp. 128-143
-
-
Kalla, C.1
Nentwich, H.2
Schlotter, M.3
Mertens, D.4
Wildenberger, K.5
Dohner, H.6
-
44
-
-
84864471033
-
Genome-wide screen of human bromodomain- containing proteins identifies Cecr2 as a novel DNA damage response protein
-
Epub 2012/06/16
-
Lee SK, Park EJ, Lee HS, Lee YS, Kwon J (2012) Genome-wide screen of human bromodomain- containing proteins identifies Cecr2 as a novel DNA damage response protein. Mol Cells 34(1):85-91, Epub 2012/06/16.
-
(2012)
Mol Cells
, vol.34
, Issue.1
, pp. 85-91
-
-
Lee, S.K.1
Park, E.J.2
Lee, H.S.3
Lee, Y.S.4
Kwon, J.5
-
45
-
-
79952381408
-
CREBBP mutations in relapsed acute lymphoblastic leukaemia
-
Epub 2011/03/11
-
Mullighan CG, Zhang J, Kasper LH, Lerach S, Payne-Turner D, Phillips LA et al (2011) CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature 471(7337):235-239, Epub 2011/03/11.
-
(2011)
Nature
, vol.471
, Issue.7337
, pp. 235-239
-
-
Mullighan, C.G.1
Zhang, J.2
Kasper, L.H.3
Lerach, S.4
Payne-Turner, D.5
Phillips, L.A.6
-
46
-
-
84867686625
-
miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells
-
Epub 2012/10/26
-
Gong AY, Eischeid AN, Xiao J, Zhao J, Chen D, Wang ZY et al (2012) miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells. BMC Cancer 12(1):492, Epub 2012/10/26.
-
(2012)
BMC Cancer
, vol.12
, Issue.1
, pp. 492
-
-
Gong, A.Y.1
Eischeid, A.N.2
Xiao, J.3
Zhao, J.4
Chen, D.5
Wang, Z.Y.6
-
47
-
-
0034104047
-
Mutations truncating the EP300 acetylase in human cancers
-
Epub 2000/03/04
-
Gayther SA, Batley SJ, Linger L, Bannister A, Thorpe K, Chin SF et al (2000) Mutations truncating the EP300 acetylase in human cancers. Nat Genet 24(3):300-303, Epub 2000/03/04.
-
(2000)
Nat Genet
, vol.24
, Issue.3
, pp. 300-303
-
-
Gayther, S.A.1
Batley, S.J.2
Linger, L.3
Bannister, A.4
Thorpe, K.5
Chin, S.F.6
-
48
-
-
0034015664
-
MOZ is fused to p300 in an acute monocytic leukemia with t(8;22)
-
Epub 2000/05/29
-
Chaffanet M, Gressin L, Preudhomme C, Soenen-Cornu V, Birnbaum D, Pebusque MJ (2000) MOZ is fused to p300 in an acute monocytic leukemia with t(8;22). Genes Chromosomes Cancer 28(2):138-144, Epub 2000/05/29.
-
(2000)
Genes Chromosomes Cancer
, vol.28
, Issue.2
, pp. 138-144
-
-
Chaffanet, M.1
Gressin, L.2
Preudhomme, C.3
Soenen-Cornu, V.4
Birnbaum, D.5
Pebusque, M.J.6
-
49
-
-
63449101161
-
The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain
-
Epub 2009/02/05
-
Grinberg-Rashi H, Ofek E, Perelman M, Skarda J, Yaron P, Hajduch M et al (2009) The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Clin Cancer Res 15(5):1755-1761, Epub 2009/02/05.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.5
, pp. 1755-1761
-
-
Grinberg-Rashi, H.1
Ofek, E.2
Perelman, M.3
Skarda, J.4
Yaron, P.5
Hajduch, M.6
-
50
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Epub 2007/10/25
-
Krivtsov AV, Armstrong SA (2007) MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7(11):823-833, Epub 2007/10/25.
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.11
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
51
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
Epub 2011/01/21
-
Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P et al (2011) Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469(7331):539-542, Epub 2011/01/21.
-
(2011)
Nature
, vol.469
, Issue.7331
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
Huang, D.4
Ong, C.K.5
Stephens, P.6
-
52
-
-
40949111565
-
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer
-
Epub 2008/03/15
-
Xia W, Nagase S, Montia AG, Kalachikov SM, Keniry M, Su T et al (2008) BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res 68(6):1667-1674, Epub 2008/03/15.
-
(2008)
Cancer Res
, vol.68
, Issue.6
, pp. 1667-1674
-
-
Xia, W.1
Nagase, S.2
Montia, A.G.3
Kalachikov, S.M.4
Keniry, M.5
Su, T.6
-
53
-
-
0029665857
-
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
-
Epub 1996/07/25
-
Yang XJ, Ogryzko VV, Nishikawa J, Howard BH, Nakatani Y (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382(6589):319-324, Epub 1996/07/25.
-
(1996)
Nature
, vol.382
, Issue.6589
, pp. 319-324
-
-
Yang, X.J.1
Ogryzko, V.V.2
Nishikawa, J.3
Howard, B.H.4
Nakatani, Y.5
-
54
-
-
63049111216
-
PCAF acetylates {beta}-catenin and improves its stability
-
Epub 2008/11/07
-
Ge X, Jin Q, Zhang F, Yan T, Zhai Q (2009) PCAF acetylates {beta}-catenin and improves its stability. Mol Biol Cell 20(1):419-427, Epub 2008/11/07.
-
(2009)
Mol Biol Cell
, vol.20
, Issue.1
, pp. 419-427
-
-
Ge, X.1
Jin, Q.2
Zhang, F.3
Yan, T.4
Zhai, Q.5
-
55
-
-
34347381275
-
Expression of PCAF, p300 and Gcn5 and more highly acetylated histone H4 in pediatric tumors
-
Epub 2007/08/30
-
Armas-Pineda C, Arenas-Huertero F, Perezpenia-Diazconti M, Chico-Ponce de Leon F, Sosa-Sainz G, Lezama P et al (2007) Expression of PCAF, p300 and Gcn5 and more highly acetylated histone H4 in pediatric tumors. J Exp Clin Cancer Res 26(2):269-276, Epub 2007/08/30.
-
(2007)
J Exp Clin Cancer Res
, vol.26
, Issue.2
, pp. 269-276
-
-
Armas-Pineda, C.1
Arenas-Huertero, F.2
Perezpenia-Diazconti, M.3
Chico-Ponce de leon, F.4
Sosa-Sainz, G.5
Lezama, P.6
-
56
-
-
84860794312
-
Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis
-
Epub 2012/04/19
-
De Semir D, Nosrati M, Bezrookove V, Dar AA, Federman S, Bienvenu G et al (2012) Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis. Proc Natl Acad Sci USA 109(18):7067-7072, Epub 2012/04/19.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.18
, pp. 7067-7072
-
-
de Semir, D.1
Nosrati, M.2
Bezrookove, V.3
Dar, A.A.4
Federman, S.5
Bienvenu, G.6
-
57
-
-
35448935143
-
Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, downregulates PI3K/Akt signaling and suppresses tumor growth in vivo
-
Epub 2007/10/19
-
Tokuda E, Fujita N, Oh-hara T, Sato S, Kurata A, Katayama R et al (2007) Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, downregulates PI3K/Akt signaling and suppresses tumor growth in vivo. Cancer Res 67(20):9666-9676, Epub 2007/10/19.
-
(2007)
Cancer Res
, vol.67
, Issue.20
, pp. 9666-9676
-
-
Tokuda, E.1
Fujita, N.2
Oh-Hara, T.3
Sato, S.4
Kurata, A.5
Katayama, R.6
-
58
-
-
0035895212
-
Serological detection of cutaneous T-cell lymphoma-associated antigens
-
Epub 2001/01/10
-
Eichmuller S, Usener D, Dummer R, Stein A, Thiel D, Schadendorf D (2001) Serological detection of cutaneous T-cell lymphoma-associated antigens. Proc Natl Acad Sci USA 98(2):629-634, Epub 2001/01/10.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.2
, pp. 629-634
-
-
Eichmuller, S.1
Usener, D.2
Dummer, R.3
Stein, A.4
Thiel, D.5
Schadendorf, D.6
-
59
-
-
84857129204
-
Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
-
Epub 2012/01/12
-
Shain AH, Giacomini CP, Matsukuma K, Karikari CA, Bashyam MD, Hidalgo M et al (2012) Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci USA 109(5):E252-E259, Epub 2012/01/12.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.5
-
-
Shain, A.H.1
Giacomini, C.P.2
Matsukuma, K.3
Karikari, C.A.4
Bashyam, M.D.5
Hidalgo, M.6
-
60
-
-
79960717223
-
Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk
-
Epub 2011/04/12
-
Liu G, Gramling S, Munoz D, Cheng D, Azad AK, Mirshams M et al (2011) Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk. Oncogene 30(29):3295-3304, Epub 2011/04/12.
-
(2011)
Oncogene
, vol.30
, Issue.29
, pp. 3295-3304
-
-
Liu, G.1
Gramling, S.2
Munoz, D.3
Cheng, D.4
Azad, A.K.5
Mirshams, M.6
-
61
-
-
64949113367
-
The SWI/SNF complex and cancer
-
Epub 2009/02/24
-
Reisman D, Glaros S, Thompson EA (2009) The SWI/SNF complex and cancer. Oncogene 28(14):1653-1668, Epub 2009/02/24.
-
(2009)
Oncogene
, vol.28
, Issue.14
, pp. 1653-1668
-
-
Reisman, D.1
Glaros, S.2
Thompson, E.A.3
-
62
-
-
76049106059
-
Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome
-
Epub 2010/02/09
-
Schneppenheim R, Fruhwald MC, Gesk S, Hasselblatt M, Jeibmann A, Kordes U et al (2010) Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome. Am J Hum Genet 86(2):279-284, Epub 2010/02/09.
-
(2010)
Am J Hum Genet
, vol.86
, Issue.2
, pp. 279-284
-
-
Schneppenheim, R.1
Fruhwald, M.C.2
Gesk, S.3
Hasselblatt, M.4
Jeibmann, A.5
Kordes, U.6
-
63
-
-
78649938792
-
Sp100 as a potent tumor suppressor: Accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program
-
Epub 2010/12/02
-
Negorev DG, Vladimirova OV, Kossenkov AV, Nikonova EV, Demarest RM, Capobianco AJ et al (2010) Sp100 as a potent tumor suppressor: accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program. Cancer Res 70(23):9991-10001, Epub 2010/12/02.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9991-10001
-
-
Negorev, D.G.1
Vladimirova, O.V.2
Kossenkov, A.V.3
Nikonova, E.V.4
Demarest, R.M.5
Capobianco, A.J.6
-
64
-
-
13444282063
-
SP100 inhibits ETS1 activity in primary endothelial cells
-
Epub 2004/12/14
-
Yordy JS, Moussa O, Pei H, Chaussabel D, Li R, Watson DK (2005) SP100 inhibits ETS1 activity in primary endothelial cells. Oncogene 24(5):916-931, Epub 2004/12/14.
-
(2005)
Oncogene
, vol.24
, Issue.5
, pp. 916-931
-
-
Yordy, J.S.1
Moussa, O.2
Pei, H.3
Chaussabel, D.4
Li, R.5
Watson, D.K.6
-
65
-
-
4143100267
-
Epstein-Barr virus (EBV) SM protein induces and recruits cellular Sp110b to stabilize mRNAs and enhance EBV lytic gene expression
-
Epub 2004/08/17
-
Nicewonger J, Suck G, Bloch D, Swaminathan S (2004) Epstein-Barr virus (EBV) SM protein induces and recruits cellular Sp110b to stabilize mRNAs and enhance EBV lytic gene expression. J Virol 78(17):9412-9422, Epub 2004/08/17.
-
(2004)
J Virol
, vol.78
, Issue.17
, pp. 9412-9422
-
-
Nicewonger, J.1
Suck, G.2
Bloch, D.3
Swaminathan, S.4
-
66
-
-
52949139429
-
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
-
Epub 2008/09/02
-
Di Bernardo MC, Crowther-Swanepoel D, Broderick P, Webb E, Sellick G, Wild R et al (2008) A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet 40(10):1204-1210, Epub 2008/09/02.
-
(2008)
Nat Genet
, vol.40
, Issue.10
, pp. 1204-1210
-
-
Di Bernardo, M.C.1
Crowther-Swanepoel, D.2
Broderick, P.3
Webb, E.4
Sellick, G.5
Wild, R.6
-
67
-
-
79953660457
-
Prognostic significance of TRIM24/TIF-1alpha gene expression in breast cancer
-
Epub 2011/03/26
-
Chambon M, Orsetti B, Berthe ML, Bascoul-Mollevi C, Rodriguez C, Duong V et al (2011) Prognostic significance of TRIM24/TIF-1alpha gene expression in breast cancer. Am J Pathol 178(4):1461-1469, Epub 2011/03/26.
-
(2011)
Am J Pathol
, vol.178
, Issue.4
, pp. 1461-1469
-
-
Chambon, M.1
Orsetti, B.2
Berthe, M.L.3
Bascoul-Mollevi, C.4
Rodriguez, C.5
Duong, V.6
-
68
-
-
84861650468
-
Overexpression of TRIM24 correlates with tumor progression in non-small cell lung cancer
-
Epub 2012/06/06
-
Li H, Sun L, Tang Z, Fu L, Xu Y, Li Z et al (2012) Overexpression of TRIM24 correlates with tumor progression in non-small cell lung cancer. PLoS One 7(5):e37657, Epub 2012/06/06.
-
(2012)
PLoS One
, vol.7
, Issue.5
-
-
Li, H.1
Sun, L.2
Tang, Z.3
Fu, L.4
Xu, Y.5
Li, Z.6
-
69
-
-
79957738075
-
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
-
Epub 2011/05/03
-
Herquel B, Ouararhni K, Khetchoumian K, Ignat M, Teletin M, Mark M et al (2011) Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. Proc Natl Acad Sci USA 108(20):8212-8217, Epub 2011/05/03.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.20
, pp. 8212-8217
-
-
Herquel, B.1
Ouararhni, K.2
Khetchoumian, K.3
Ignat, M.4
Teletin, M.5
Mark, M.6
-
70
-
-
36549086517
-
Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha
-
Epub 2007/11/21
-
Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M et al (2007) Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat Genet 39(12):1500-1506, Epub 2007/11/21.
-
(2007)
Nat Genet
, vol.39
, Issue.12
, pp. 1500-1506
-
-
Khetchoumian, K.1
Teletin, M.2
Tisserand, J.3
Mark, M.4
Herquel, B.5
Ignat, M.6
-
71
-
-
78650353481
-
TRIM24 links a noncanonical histone signature to breast cancer
-
Epub 2010/12/18
-
Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S et al (2010) TRIM24 links a noncanonical histone signature to breast cancer. Nature 468(7326):927-932, Epub 2010/12/18.
-
(2010)
Nature
, vol.468
, Issue.7326
, pp. 927-932
-
-
Tsai, W.W.1
Wang, Z.2
Yiu, T.T.3
Akdemir, K.C.4
Xia, W.5
Winter, S.6
-
72
-
-
77956685002
-
Analysis of copy number variations of BS69 in multiple types of hematological malignancies
-
Epub 2010/04/29
-
Yang H, Zhang C, Zhao X, Wu Q, Fu X, Yu B et al (2010) Analysis of copy number variations of BS69 in multiple types of hematological malignancies. Ann Hematol 89(10):959-964, Epub 2010/04/29.
-
(2010)
Ann Hematol
, vol.89
, Issue.10
, pp. 959-964
-
-
Yang, H.1
Zhang, C.2
Zhao, X.3
Wu, Q.4
Fu, X.5
Yu, B.6
-
73
-
-
10744233204
-
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Epub 2003/12/04
-
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF et al (2003) EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 115(5):523-535, Epub 2003/12/04.
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
Fuks, F.4
Bye, J.5
Chin, S.F.6
-
74
-
-
70349669271
-
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
-
Moriniere J, Rousseaux S, Steuerwald U, Soler-Lopez M, Curtet S, Vitte AL et al (2009) Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. Nature 461(7264):664-668.
-
(2009)
Nature
, vol.461
, Issue.7264
, pp. 664-668
-
-
Moriniere, J.1
Rousseaux, S.2
Steuerwald, U.3
Soler-Lopez, M.4
Curtet, S.5
Vitte, A.L.6
-
75
-
-
84866338076
-
Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites
-
Epub 2012/07/14
-
Vidler LR, Brown N, Knapp S, Hoelder S (2012) Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites. J Med Chem 55(17):7346-7359, Epub 2012/07/14.
-
(2012)
J Med Chem
, vol.55
, Issue.17
, pp. 7346-7359
-
-
Vidler, L.R.1
Brown, N.2
Knapp, S.3
Hoelder, S.4
-
76
-
-
14744276712
-
Selective small molecules blocking HIV-1 Tat and coactivator PCAF association
-
Epub 2005/02/24
-
Zeng L, Li J, Muller M, Yan S, Mujtaba S, Pan C et al (2005) Selective small molecules blocking HIV-1 Tat and coactivator PCAF association. J Am Chem Soc 127(8):2376-2377, Epub 2005/02/24.
-
(2005)
J Am Chem Soc
, vol.127
, Issue.8
, pp. 2376-2377
-
-
Zeng, L.1
Li, J.2
Muller, M.3
Yan, S.4
Mujtaba, S.5
Pan, C.6
-
77
-
-
30744456492
-
Target structure-based discovery of small molecules that block human p53 and CREB binding protein association
-
Epub 2006/01/24
-
Sachchidanand, Resnick-Silverman L, Yan S, Mutjaba S, Liu WJ, Zeng L et al (2006) Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol 13(1):81-90, Epub 2006/01/24.
-
(2006)
Chem Biol
, vol.13
, Issue.1
, pp. 81-90
-
-
Sachchidanand Resnick-Silverman, L.1
Yan, S.2
Mutjaba, S.3
Liu, W.J.4
Zeng, L.5
-
78
-
-
79955410483
-
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes
-
Epub 2011/04/26
-
Borah JC, Mujtaba S, Karakikes I, Zeng L, Muller M, Patel J et al (2011) A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem Biol 18(4):531-541, Epub 2011/04/26.
-
(2011)
Chem Biol
, vol.18
, Issue.4
, pp. 531-541
-
-
Borah, J.C.1
Mujtaba, S.2
Karakikes, I.3
Zeng, L.4
Muller, M.5
Patel, J.6
-
79
-
-
84856366631
-
Tetrahydroquinoline derivatives as bromodomain inhibitors. International patent WO/2011/054848
-
Demont E, Gosmini R (2011) Tetrahydroquinoline derivatives as bromodomain inhibitors. International patent WO/2011/054848. GLAXOSMITHKLINE LLC:1-199.
-
(2011)
GLAXOSMITHKLINE LLC
, pp. 1-199
-
-
Demont, E.1
Gosmini, R.2
-
80
-
-
79955433622
-
Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors
-
Epub 2011/04/26
-
Ito T, Umehara T, Sasaki K, Nakamura Y, Nishino N, Terada T et al (2011) Real-time imaging of histone H4K12-specific acetylation determines the modes of action of histone deacetylase and bromodomain inhibitors. Chem Biol 18(4):495-507, Epub 2011/04/26.
-
(2011)
Chem Biol
, vol.18
, Issue.4
, pp. 495-507
-
-
Ito, T.1
Umehara, T.2
Sasaki, K.3
Nakamura, Y.4
Nishino, N.5
Terada, T.6
-
81
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
Epub 2010/09/28
-
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O et al (2010) Selective inhibition of BET bromodomains. Nature 468(7327):1067-1073, Epub 2010/09/28.
-
(2010)
Nature
, vol.468
, Issue.7327
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
-
82
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Epub 2010/11/12
-
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung CW et al (2010) Suppression of inflammation by a synthetic histone mimic. Nature 468(7327):1119-1123, Epub 2010/11/12.
-
(2010)
Nature
, vol.468
, Issue.7327
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
Beinke, S.4
Dewell, S.5
Chung, C.W.6
-
83
-
-
79958078949
-
Discovery and characterization of small molecule inhibitors of the BET family bromodomains
-
Epub 2011/05/17
-
Chung CW, Coste H, White JH, Mirguet O, Wilde J, Gosmini RL et al (2011) Discovery and characterization of small molecule inhibitors of the BET family bromodomains. J Med Chem 54(11):3827-3838, Epub 2011/05/17.
-
(2011)
J Med Chem
, vol.54
, Issue.11
, pp. 3827-3838
-
-
Chung, C.W.1
Coste, H.2
White, J.H.3
Mirguet, O.4
Wilde, J.5
Gosmini, R.L.6
-
84
-
-
84857913614
-
Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family
-
Epub 2011/12/06
-
Filippakopoulos P, Picaud S, Fedorov O, Keller M, Wrobel M, Morgenstern O et al (2012) Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family. Bioorg Med Chem 20(6):1878-1886, Epub 2011/12/06.
-
(2012)
Bioorg Med Chem
, vol.20
, Issue.6
, pp. 1878-1886
-
-
Filippakopoulos, P.1
Picaud, S.2
Fedorov, O.3
Keller, M.4
Wrobel, M.5
Morgenstern, O.6
-
85
-
-
80053924872
-
3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands
-
Epub 2011/08/20
-
Hewings DS, Wang M, Philpott M, Fedorov O, Uttarkar S, Filippakopoulos P et al (2011) 3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands. J Med Chem 54(19):6761-6770, Epub 2011/08/20.
-
(2011)
J Med Chem
, vol.54
, Issue.19
, pp. 6761-6770
-
-
Hewings, D.S.1
Wang, M.2
Philpott, M.3
Fedorov, O.4
Uttarkar, S.5
Filippakopoulos, P.6
-
86
-
-
84856399470
-
Fragmentbased discovery of bromodomain inhibitors part 2: Optimization of phenylisoxazole sulfonamides
-
Epub 2011/12/06
-
Bamborough P, Diallo H, Goodacre JD, Gordon L, Lewis A, Seal JT et al (2012) Fragmentbased discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides. J Med Chem 55(2):587-596, Epub 2011/12/06.
-
(2012)
J Med Chem
, vol.55
, Issue.2
, pp. 587-596
-
-
Bamborough, P.1
Diallo, H.2
Goodacre, J.D.3
Gordon, L.4
Lewis, A.5
Seal, J.T.6
-
87
-
-
0037439788
-
BRD4- NUT fusion oncogene: A novel mechanism in aggressive carcinoma
-
Epub 2003/01/25
-
French CA, Miyoshi I, Kubonishi I, Grier HE, Perez-Atayde AR, Fletcher JA (2003) BRD4- NUT fusion oncogene: a novel mechanism in aggressive carcinoma. Cancer Res 63(2):304-307, Epub 2003/01/25.
-
(2003)
Cancer Res
, vol.63
, Issue.2
, pp. 304-307
-
-
French, C.A.1
Miyoshi, I.2
Kubonishi, I.3
Grier, H.E.4
Perez-Atayde, A.R.5
Fletcher, J.A.6
-
88
-
-
77953714098
-
Demystified molecular pathology of NUT midline carcinomas
-
Epub 2008/06/17
-
French CA (2010) Demystified molecular pathology of NUT midline carcinomas. J Clin Pathol 63(6):492-496, Epub 2008/06/17.
-
(2010)
J Clin Pathol
, vol.63
, Issue.6
, pp. 492-496
-
-
French, C.A.1
-
89
-
-
0034674896
-
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
-
Epub 2000/08/17
-
Dang TP, Gazdar AF, Virmani AK, Sepetavec T, Hande KR, Minna JD et al (2000) Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. J Natl Cancer Inst 92(16):1355-1357, Epub 2000/08/17.
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.16
, pp. 1355-1357
-
-
Dang, T.P.1
Gazdar, A.F.2
Virmani, A.K.3
Sepetavec, T.4
Hande, K.R.5
Minna, J.D.6
-
90
-
-
2942612219
-
p300/CBP and cancer
-
Epub 2004/05/25
-
Iyer NG, Ozdag H, Caldas C (2004) p300/CBP and cancer. Oncogene 23(24):4225-4231, Epub 2004/05/25.
-
(2004)
Oncogene
, vol.23
, Issue.24
, pp. 4225-4231
-
-
Iyer, N.G.1
Ozdag, H.2
Caldas, C.3
-
91
-
-
9544220768
-
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein
-
Epub 1996/09/01
-
Borrow J, Stanton VP Jr, Andresen JM, Becher R, Behm FG, Chaganti RS et al (1996) The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet 14(1):33-41, Epub 1996/09/01.
-
(1996)
Nat Genet
, vol.14
, Issue.1
, pp. 33-41
-
-
Borrow, J.1
Stanton Jr., V.P.2
Andresen, J.M.3
Becher, R.4
Behm, F.G.5
Chaganti, R.S.6
-
92
-
-
0035865032
-
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16) (q22;p13)
-
Epub 2001/02/07
-
Panagopoulos I, Fioretos T, Isaksson M, Samuelsson U, Billstrom R, Strombeck B et al (2001) Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16) (q22;p13). Hum Mol Genet 10(4):395-404, Epub 2001/02/07.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.4
, pp. 395-404
-
-
Panagopoulos, I.1
Fioretos, T.2
Isaksson, M.3
Samuelsson, U.4
Billstrom, R.5
Strombeck, B.6
-
93
-
-
0022258983
-
Chronic myelogenous leukemia with translocation (8;22): Report of a new case
-
Epub 1985/08/01
-
Lai JL, Jouet JP, Bauters F, Deminatti M (1985) Chronic myelogenous leukemia with translocation (8;22): report of a new case. Cancer Genet Cytogenet 17(4):365-366, Epub 1985/08/01.
-
(1985)
Cancer Genet Cytogenet
, vol.17
, Issue.4
, pp. 365-366
-
-
Lai, J.L.1
Jouet, J.P.2
Bauters, F.3
Deminatti, M.4
-
94
-
-
0035142070
-
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22) (p11;q13) chromosome translocation
-
Epub 2001/03/13
-
Kitabayashi I, Aikawa Y, Yokoyama A, Hosoda F, Nagai M, Kakazu N et al (2001) Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22) (p11;q13) chromosome translocation. Leukemia 15(1):89-94, Epub 2001/03/13.
-
(2001)
Leukemia
, vol.15
, Issue.1
, pp. 89-94
-
-
Kitabayashi, I.1
Aikawa, Y.2
Yokoyama, A.3
Hosoda, F.4
Nagai, M.5
Kakazu, N.6
-
95
-
-
0030792867
-
All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders
-
Rowley JD, Reshmi S, Sobulo O, Musvee T, Anastasi J, Raimondi S et al (1997) All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders. Blood 90(2):535-541.
-
(1997)
Blood
, vol.90
, Issue.2
, pp. 535-541
-
-
Rowley, J.D.1
Reshmi, S.2
Sobulo, O.3
Musvee, T.4
Anastasi, J.5
Raimondi, S.6
-
96
-
-
0030885075
-
Novel MLLCBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16) (q23;p13) chromosome translocation
-
Epub 1997/09/18
-
Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A et al (1997) Novel MLLCBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16) (q23;p13) chromosome translocation. Genes Chromosomes Cancer 20(1):60-63, Epub 1997/09/18.
-
(1997)
Genes Chromosomes Cancer
, vol.20
, Issue.1
, pp. 60-63
-
-
Satake, N.1
Ishida, Y.2
Otoh, Y.3
Hinohara, S.4
Kobayashi, H.5
Sakashita, A.6
-
97
-
-
0031570335
-
Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3
-
Giles RH, Petrij F, Dauwerse HG, den Hollander AI, Lushnikova T, van Ommen GJ et al (1997) Construction of a 1.2-Mb contig surrounding, and molecular analysis of, the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3. Genomics 42(1):96-114.
-
(1997)
Genomics
, vol.42
, Issue.1
, pp. 96-114
-
-
Giles, R.H.1
Petrij, F.2
Dauwerse, H.G.3
den Hollander, A.I.4
Lushnikova, T.5
van Ommen, G.J.6
-
98
-
-
84867881861
-
Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment
-
Epub 2012/04/21
-
Quintas-Cardama A, Qiu YH, Post SM, Zhang Y, Creighton CJ, Cortes J et al (2012) Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment. Cancer 118(21):5283-5292, Epub 2012/04/21.
-
(2012)
Cancer
, vol.118
, Issue.21
, pp. 5283-5292
-
-
Quintas-Cardama, A.1
Qiu, Y.H.2
Post, S.M.3
Zhang, Y.4
Creighton, C.J.5
Cortes, J.6
-
99
-
-
84872032367
-
Preparation of anti-BRDTNY polyclonal antibody and expression of BRDT-NY protein in digestive tract tumors
-
Epub 2012/08/07
-
Ding WM, Yang L, Zheng Y, Sun HY, Liang H, Wang JJ (2012) Preparation of anti-BRDTNY polyclonal antibody and expression of BRDT-NY protein in digestive tract tumors. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28(8):847-850, Epub 2012/08/07.
-
(2012)
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
, vol.28
, Issue.8
, pp. 847-850
-
-
Ding, W.M.1
Yang, L.2
Zheng, Y.3
Sun, H.Y.4
Liang, H.5
Wang, J.J.6
-
100
-
-
0035985214
-
Gene expression patterns in human liver cancers
-
Epub 2002/06/12
-
Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J et al (2002) Gene expression patterns in human liver cancers. Mol Biol Cell 13(6):1929-1939, Epub 2002/06/12.
-
(2002)
Mol Biol Cell
, vol.13
, Issue.6
, pp. 1929-1939
-
-
Chen, X.1
Cheung, S.T.2
So, S.3
Fan, S.T.4
Barry, C.5
Higgins, J.6
-
101
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Epub 2000/02/17
-
Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A et al (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403(6769):503-511, Epub 2000/02/17.
-
(2000)
Nature
, vol.403
, Issue.6769
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
Ma, C.4
Lossos, I.S.5
Rosenwald, A.6
-
102
-
-
18244409687
-
Gene expression profiling predicts clinical outcome of breast cancer
-
Epub 2002/02/02
-
van't Veer LJ, Dai H, van de Vijver MJ, He YD, Hart AA, Mao M et al (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415(6871):530-536, Epub 2002/02/02.
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 530-536
-
-
Van't veer, L.J.1
Dai, H.2
van de Vijver, M.J.3
He, Y.D.4
Hart, A.A.5
Mao, M.6
-
103
-
-
0038137601
-
Gene expression profiles of human breast cancer progression
-
Epub 2003/04/26
-
Ma XJ, Salunga R, Tuggle JT, Gaudet J, Enright E, McQuary P et al (2003) Gene expression profiles of human breast cancer progression. Proc Natl Acad Sci USA 100(10):5974-5979, Epub 2003/04/26.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.10
, pp. 5974-5979
-
-
Ma, X.J.1
Salunga, R.2
Tuggle, J.T.3
Gaudet, J.4
Enright, E.5
McQuary, P.6
-
104
-
-
77956914230
-
Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers
-
Epub 2010/06/29
-
Caron C, Lestrat C, Marsal S, Escoffier E, Curtet S, Virolle V et al (2010) Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers. Oncogene 29(37):5171-5181, Epub 2010/06/29.
-
(2010)
Oncogene
, vol.29
, Issue.37
, pp. 5171-5181
-
-
Caron, C.1
Lestrat, C.2
Marsal, S.3
Escoffier, E.4
Curtet, S.5
Virolle, V.6
-
105
-
-
70350537013
-
ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors
-
Epub 2009/10/22
-
Ciro M, Prosperini E, Quarto M, Grazini U, Walfridsson J, McBlane F et al (2009) ATAD2 is a novel cofactor for MYC, overexpressed and amplified in aggressive tumors. Cancer Res 69(21):8491-8498, Epub 2009/10/22.
-
(2009)
Cancer Res
, vol.69
, Issue.21
, pp. 8491-8498
-
-
Ciro, M.1
Prosperini, E.2
Quarto, M.3
Grazini, U.4
Walfridsson, J.5
McBlane, F.6
-
106
-
-
0034326257
-
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines
-
Epub 2000/11/21
-
Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K et al (2000) BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Cancer Res 60(21):6171-6177, Epub 2000/11/21.
-
(2000)
Cancer Res
, vol.60
, Issue.21
, pp. 6171-6177
-
-
Wong, A.K.1
Shanahan, F.2
Chen, Y.3
Lian, L.4
Ha, P.5
Hendricks, K.6
-
107
-
-
0035962635
-
When the SWI/SNF complex remodels...the cell cycle
-
Epub 2001/06/23
-
Muchardt C, Yaniv M (2001) When the SWI/SNF complex remodels...the cell cycle. Oncogene 20(24):3067-3075, Epub 2001/06/23.
-
(2001)
Oncogene
, vol.20
, Issue.24
, pp. 3067-3075
-
-
Muchardt, C.1
Yaniv, M.2
-
108
-
-
42949178435
-
Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines
-
Epub 2008/04/05
-
Medina PP, Romero OA, Kohno T, Montuenga LM, Pio R, Yokota J et al (2008) Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines. Hum Mutat 29(5):617-622, Epub 2008/04/05.
-
(2008)
Hum Mutat
, vol.29
, Issue.5
, pp. 617-622
-
-
Medina, P.P.1
Romero, O.A.2
Kohno, T.3
Montuenga, L.M.4
Pio, R.5
Yokota, J.6
-
109
-
-
0032963671
-
c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function
-
Epub 1999/05/13
-
Cheng SW, Davies KP, Yung E, Beltran RJ, Yu J, Kalpana GV (1999) c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat Genet 22(1):102-105, Epub 1999/05/13.
-
(1999)
Nat Genet
, vol.22
, Issue.1
, pp. 102-105
-
-
Cheng, S.W.1
Davies, K.P.2
Yung, E.3
Beltran, R.J.4
Yu, J.5
Kalpana, G.V.6
-
110
-
-
0037308717
-
Loss of BRG1/ BRM in human lung cancer cell lines and primary lung cancers: Correlation with poor prognosis
-
Epub 2003/02/05
-
Reisman DN, Sciarrotta J, Wang W, Funkhouser WK, Weissman BE (2003) Loss of BRG1/ BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis. Cancer Res 63(3):560-566, Epub 2003/02/05.
-
(2003)
Cancer Res
, vol.63
, Issue.3
, pp. 560-566
-
-
Reisman, D.N.1
Sciarrotta, J.2
Wang, W.3
Funkhouser, W.K.4
Weissman, B.E.5
-
111
-
-
0035199533
-
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies
-
Epub 2001/01/09
-
Decristofaro MF, Betz BL, Rorie CJ, Reisman DN, Wang W, Weissman BE (2001) Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies. J Cell Physiol 186(1):136-145, Epub 2001/01/09.
-
(2001)
J Cell Physiol
, vol.186
, Issue.1
, pp. 136-145
-
-
Decristofaro, M.F.1
Betz, B.L.2
Rorie, C.J.3
Reisman, D.N.4
Wang, W.5
Weissman, B.E.6
-
112
-
-
12344262099
-
Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme
-
Epub 2004/11/13
-
Hill DA, Chiosea S, Jamaluddin S, Roy K, Fischer AH, Boyd DD et al (2004) Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme. J Cell Sci 117(Pt 24):5847-5854, Epub 2004/11/13.
-
(2004)
J Cell Sci
, vol.117
, Issue.Pt 24
, pp. 5847-5854
-
-
Hill, D.A.1
Chiosea, S.2
Jamaluddin, S.3
Roy, K.4
Fischer, A.H.5
Boyd, D.D.6
-
113
-
-
61349129513
-
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a
-
Epub 2009/01/20
-
Becker TM, Haferkamp S, Dijkstra MK, Scurr LL, Frausto M, Diefenbach E et al (2009) The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Mol Cancer 8:4, Epub 2009/01/20
-
(2009)
Mol Cancer
, vol.8
, pp. 4
-
-
Becker, T.M.1
Haferkamp, S.2
Dijkstra, M.K.3
Scurr, L.L.4
Frausto, M.5
Diefenbach, E.6
|