Sp100 as a potent tumor suppressor: Accelerated senescence and rapid malignant transformation of human fibroblasts through modulation of an embryonic stem cell program

Cancer Research

Volumn 70, Issue 23, 2010, Pages 9991-10001

  Negorev, Dmitri G ^a   Vladimirova, Olga V ^a   Kossenkov V, Andrew ^a   Nikonova V, Elena ^a   Demarest, Renee M ^a   Capobianco, Anthony J ^b   Showe, Michael K ^a   Rauscher III, Frank J ^a   Showe, Louise C ^a   Maul, Gerd G ^a  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; ISOPROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN P53; RAS PROTEIN; SP 100 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL DIVISION; CELL TRANSDIFFERENTIATION; EMBRYONIC STEM CELL; EPITHELIUM CELL; FIBROBLAST; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; MALIGNANT TRANSFORMATION; MESENCHYMAL STEM CELL; MICROSATELLITE MARKER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE; STEM CELL;

ANIMALS; ANTIGENS, NUCLEAR; AUTOANTIGENS; BLOTTING, WESTERN; CELL AGING; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; EMBRYONIC STEM CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROBLASTS; GENE EXPRESSION PROFILING; HEK293 CELLS; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-MYC; RAS PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEINS;

EID: 78649938792     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1483     Document Type: Article

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