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Volumn 143, Issue 3, 2012, Pages

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells

Author keywords

HGF; Liver Cancer; Mouse Model; RNA Processing

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; LUCIFERASE; MESSENGER RNA; MICRORNA; MICRORNA 449; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE KINASE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SMALL INTERFERING RNA; TRICHOSTATIN A; UNCLASSIFIED DRUG;

EID: 84865479772     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.05.033     Document Type: Article
Times cited : (176)

References (52)
  • 1
    • 0030626221 scopus 로고    scopus 로고
    • Treatment of hepatocellular carcinoma
    • M. Colombo Treatment of hepatocellular carcinoma J Viral Hepat 4 Suppl 1 1997 125 130
    • (1997) J Viral Hepat , vol.4 , Issue.SUPPL. 1 , pp. 125-130
    • Colombo, M.1
  • 5
    • 21244467166 scopus 로고    scopus 로고
    • Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies
    • DOI 10.1200/JCO.2005.16.600
    • K.N. Bhalla Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies J Clin Oncol 23 2005 3971 3993 (Pubitemid 46218700)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.17 , pp. 3971-3993
    • Bhalla, K.N.1
  • 7
    • 34248631385 scopus 로고    scopus 로고
    • The role of histone deacetylases (HDACs) in human cancer
    • DOI 10.1016/j.molonc.2007.01.001, PII S1574789107000026
    • S. Ropero, M. Esteller The role of histone deacetylases (HDACs) in human cancer Mol Oncol 1 2007 19 25 (Pubitemid 46776612)
    • (2007) Molecular Oncology , vol.1 , Issue.1 , pp. 19-25
    • Ropero, S.1    Esteller, M.2
  • 8
    • 34547549214 scopus 로고    scopus 로고
    • Epigenetic therapy in cancer: Molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors
    • R. Schneider-Stock, M. Ocker Epigenetic therapy in cancer: molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors IDrugs 10 2007 557 561 (Pubitemid 47186508)
    • (2007) IDrugs , vol.10 , Issue.8 , pp. 557-561
    • Scneider-Stock, R.1    Ocker, M.2
  • 9
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • M.F. Fraga, E. Ballestar, A. Villar-Garea Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer Nat Genet 37 2005 391 400
    • (2005) Nat Genet , vol.37 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3
  • 11
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • DOI 10.1038/nrc1779
    • S. Minucci, P.G. Pelicci Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 6 2006 38 51 (Pubitemid 43054973)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.1 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 12
    • 61849144810 scopus 로고    scopus 로고
    • HDAC family: What are the cancer relevant targets?
    • O. Witt, H.E. Deubzer, T. Milde HDAC family: what are the cancer relevant targets? Cancer Lett 277 2009 8 21
    • (2009) Cancer Lett , vol.277 , pp. 8-21
    • Witt, O.1    Deubzer, H.E.2    Milde, T.3
  • 13
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • C.B. Yoo, P.A. Jones Epigenetic therapy of cancer: past, present and future Nat Rev Drug Discov 5 2006 37 50
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 14
    • 80052417803 scopus 로고    scopus 로고
    • Clinical significance of histone deacetylases 1, 2, 3, and 7: HDAC2 is an independent predictor of survival in HCC
    • K. Quint, A. Agaimy, P. Di Fazio Clinical significance of histone deacetylases 1, 2, 3, and 7: HDAC2 is an independent predictor of survival in HCC Virchows Arch 459 2011 129 139
    • (2011) Virchows Arch , vol.459 , pp. 129-139
    • Quint, K.1    Agaimy, A.2    Di Fazio, P.3
  • 16
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 17
    • 24344494340 scopus 로고    scopus 로고
    • How microRNAs control cell division, differentiation and death
    • DOI 10.1016/j.gde.2005.08.005, PII S0959437X05001346
    • E.A. Miska How microRNAs control cell division, differentiation and death Curr Opin Genet Dev 15 2005 563 568 (Pubitemid 41262414)
    • (2005) Current Opinion in Genetics and Development , vol.15 , Issue.5 , pp. 563-568
    • Miska, E.A.1
  • 18
    • 56649097358 scopus 로고    scopus 로고
    • Loss of 13q is associated with genes involved in cell cycle and proliferation in dedifferentiated hepatocellular carcinoma
    • B. Skawran, D. Steinemann, T. Becker Loss of 13q is associated with genes involved in cell cycle and proliferation in dedifferentiated hepatocellular carcinoma Mod Pathol 21 2008 1479 1489
    • (2008) Mod Pathol , vol.21 , pp. 1479-1489
    • Skawran, B.1    Steinemann, D.2    Becker, T.3
  • 22
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • J. Vandesompele, K. De Preter, F. Pattyn Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol 3 2002 RESEARCH0034
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 23
    • 45449087921 scopus 로고    scopus 로고
    • QBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
    • J. Hellemans, G. Mortier, A. De Paepe qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data Genome Biol 8 2007 R19
    • (2007) Genome Biol , vol.8 , pp. 19
    • Hellemans, J.1    Mortier, G.2    De Paepe, A.3
  • 25
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • B.P. Lewis, C.B. Burge, D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20 (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 27
    • 0034693753 scopus 로고    scopus 로고
    • Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
    • K.A. Furge, Y.W. Zhang, G.F. Vande Woude Met receptor tyrosine kinase: enhanced signaling through adapter proteins Oncogene 19 2000 5582 5589
    • (2000) Oncogene , vol.19 , pp. 5582-5589
    • Furge, K.A.1    Zhang, Y.W.2    Vande Woude, G.F.3
  • 29
    • 19644395911 scopus 로고    scopus 로고
    • HGF/SF-Met signaling in tumor progression
    • DOI 10.1038/sj.cr.7290264
    • C.F. Gao, G.F. Vande Woude HGF/SF-Met signaling in tumor progression Cell Res 15 2005 49 51 (Pubitemid 41653965)
    • (2005) Cell Research , vol.15 , Issue.1 , pp. 49-51
    • Gao, C.F.1    Vande Woude, G.F.2
  • 30
    • 77955700612 scopus 로고    scopus 로고
    • Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis
    • S.A. Lee, S. Ladu, M. Evert Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis Hepatology 52 2010 506 517
    • (2010) Hepatology , vol.52 , pp. 506-517
    • Lee, S.A.1    Ladu, S.2    Evert, M.3
  • 31
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • S. Whittaker, R. Marais, A.X. Zhu The role of signaling pathways in the development and treatment of hepatocellular carcinoma Oncogene 29 2010 4989 5005
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 32
    • 84861567957 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma
    • Y.X. Fang, J.L. Xue, Q. Shen MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma Hepatology 55 2012 1852 1862
    • (2012) Hepatology , vol.55 , pp. 1852-1862
    • Fang, Y.X.1    Xue, J.L.2    Shen, Q.3
  • 33
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • J.A. Fahrner, S. Eguchi, J.G. Herman Dependence of histone modifications and gene expression on DNA hypermethylation in cancer Cancer Res 62 2002 7213 7218 (Pubitemid 36025241)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 35
    • 66049111715 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors as novel anticancer therapeutics
    • D.R. Walkinshaw, X.J. Yang Histone deacetylase inhibitors as novel anticancer therapeutics Curr Oncol 15 2008 237 243
    • (2008) Curr Oncol , vol.15 , pp. 237-243
    • Walkinshaw, D.R.1    Yang, X.J.2
  • 36
    • 0141885037 scopus 로고    scopus 로고
    • From discovery to the coming generation of histone deacetylase inhibitors
    • DOI 10.2174/0929867033456602
    • M. Yoshida, A. Matsuyama, Y. Komatsu From discovery to the coming generation of histone deacetylase inhibitors Curr Med Chem 10 2003 2351 2358 (Pubitemid 37236392)
    • (2003) Current Medicinal Chemistry , vol.10 , Issue.22 , pp. 2351-2358
    • Yoshida, M.1    Matsuyama, A.2    Komatsu, Y.3    Nishino, N.4
  • 37
    • 26444439216 scopus 로고    scopus 로고
    • Prospects: Histone deacetylase inhibitors
    • DOI 10.1002/jcb.20532
    • M. Dokmanovic, P.A. Marks Prospects: histone deacetylase inhibitors J Cell Biochem 96 2005 293 304 (Pubitemid 41437862)
    • (2005) Journal of Cellular Biochemistry , vol.96 , Issue.2 , pp. 293-304
    • Dokmanovic, M.1    Marks, P.A.2
  • 39
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 41
    • 38049044753 scopus 로고    scopus 로고
    • Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer
    • U. Lehmann, B. Hasemeier, M. Christgen Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer J Pathol 214 2008 17 24
    • (2008) J Pathol , vol.214 , pp. 17-24
    • Lehmann, U.1    Hasemeier, B.2    Christgen, M.3
  • 42
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • DOI 10.1016/j.ccr.2006.04.020, PII S1535610806001437
    • Y. Saito, G. Liang, G. Egger Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells Cancer Cell 9 2006 435 443 (Pubitemid 43832188)
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6    Jones, P.A.7
  • 43
    • 58549108465 scopus 로고    scopus 로고
    • Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells
    • Y. Saito, J.M. Friedman, Y. Chihara Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells Biochem Biophys Res Commun 379 2009 726 731
    • (2009) Biochem Biophys Res Commun , vol.379 , pp. 726-731
    • Saito, Y.1    Friedman, J.M.2    Chihara, Y.3
  • 44
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • DOI 10.1158/0008-5472.CAN-05-3632
    • G.K. Scott, M.D. Mattie, C.E. Berger Rapid alteration of microRNA levels by histone deacetylase inhibition Cancer Res 66 2006 1277 1281 (Pubitemid 43259904)
    • (2006) Cancer Research , vol.66 , Issue.3 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 45
    • 33749598345 scopus 로고    scopus 로고
    • Epigenetic activation of tumor suppressor microRNAs in human cancer cells
    • Y. Saito, P.A. Jones Epigenetic activation of tumor suppressor microRNAs in human cancer cells Cell Cycle 5 2006 2220 2222 (Pubitemid 44546557)
    • (2006) Cell Cycle , vol.5 , Issue.19 , pp. 2220-2222
    • Saito, Y.1    Jones, P.A.2
  • 46
    • 76749102887 scopus 로고    scopus 로고
    • E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis
    • M. Lize, S. Pilarski, M. Dobbelstein E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis Cell Death Differ 17 2010 452 458
    • (2010) Cell Death Differ , vol.17 , pp. 452-458
    • Lize, M.1    Pilarski, S.2    Dobbelstein, M.3
  • 47
    • 64949190804 scopus 로고    scopus 로고
    • MiR-449a targets HDAC-1 and induces growth arrest in prostate cancer
    • E.J. Noonan, R.F. Place, D. Pookot miR-449a targets HDAC-1 and induces growth arrest in prostate cancer Oncogene 28 2009 1714 1724
    • (2009) Oncogene , vol.28 , pp. 1714-1724
    • Noonan, E.J.1    Place, R.F.2    Pookot, D.3
  • 48
    • 79954507936 scopus 로고    scopus 로고
    • MiR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells
    • E.J. Noonan, R.F. Place, S. Basak miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells Oncotarget 1 2010 349 358
    • (2010) Oncotarget , vol.1 , pp. 349-358
    • Noonan, E.J.1    Place, R.F.2    Basak, S.3
  • 49
    • 70349145414 scopus 로고    scopus 로고
    • MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer
    • P. Olson, J. Lu, H. Zhang MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer Genes Dev 23 2009 2152 2165
    • (2009) Genes Dev , vol.23 , pp. 2152-2165
    • Olson, P.1    Lu, J.2    Zhang, H.3
  • 50
    • 70350111289 scopus 로고    scopus 로고
    • MiR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
    • X. Yang, M. Feng, X. Jiang miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A Genes Dev 23 2009 2388 2393
    • (2009) Genes Dev , vol.23 , pp. 2388-2393
    • Yang, X.1    Feng, M.2    Jiang, X.3
  • 51
    • 33750287121 scopus 로고    scopus 로고
    • Involvement of c-Met/Hepatocyte Growth Factor Pathway in Cholangiocarcinoma Cell Invasion and Its Therapeutic Inhibition With Small Interfering RNA Specific for c-Met
    • DOI 10.1016/j.jss.2006.05.031, PII S0022480406002940
    • K. Leelawat, S. Leelawat, P. Tepaksorn Involvement of c-Met/hepatocyte growth factor pathway in cholangiocarcinoma cell invasion and its therapeutic inhibition with small interfering RNA specific for c-Met J Surg Res 136 2006 78 84 (Pubitemid 44634563)
    • (2006) Journal of Surgical Research , vol.136 , Issue.1 , pp. 78-84
    • Leelawat, K.1    Leelawat, S.2    Tepaksorn, P.3    Rattanasinganchan, P.4    Leungchaweng, A.5    Tohtong, R.6    Sobhon, P.7
  • 52
    • 34547558390 scopus 로고    scopus 로고
    • Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: Implications for tumour invasion
    • DOI 10.1038/sj.bjc.6603884, PII 6603884
    • P.C. Ma, M.S. Tretiakova, V. Nallasura Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion Br J Cancer 97 2007 368 377 (Pubitemid 47196754)
    • (2007) British Journal of Cancer , vol.97 , Issue.3 , pp. 368-377
    • Ma, P.C.1    Tretiakova, M.S.2    Nallasura, V.3    Jagadeeswaran, R.4    Husain, A.N.5    Salgia, R.6


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