All patients with the t(11; 16)(q23; p13.3) That involves MLL and CBP have treatment-related hematologic disorders

Blood

Volumn 90, Issue 2, 1997, Pages 535-541

  Rowley, Janet D ^a   Reshmi, Shalini ^b   Sobulo, Olatoyosi ^b   Musvee, Tarannum ^b   Anastasi, John ^b   Raimondi, Susana ^b   Schneider, Nancy R ^b   Barredo, Julio C ^b   Cantu, Eduardo S ^b   Schlegelberger, Brigitte ^b   Behm, Frederick ^b   Doggett, Norman A ^b   Borrow, Julian ^b   Zeleznik Le, Nancy ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CONTIG; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE;

ACETYLATION; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE MYELOMONOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHROMOSOME 11Q; CHROMOSOME 16; CHROMOSOME TRANSLOCATION 11; CHRONIC MYELOMONOCYTIC LEUKEMIA; CLINICAL ARTICLE; COSMID; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; HEMATOLOGIC DISEASE; HEREDITARY HEMOLYTIC ANEMIA; HUMAN; HUMAN CELL; MALE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ADOLESCENT; ADULT; ANTINEOPLASTIC AGENTS; CHILD; CHILD, PRESCHOOL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 16; CREB-BINDING PROTEIN; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASMS; NEOPLASMS, SECOND PRIMARY; NUCLEAR PROTEINS; PROTO-ONCOGENES; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; ZINC FINGERS;

EID: 0030792867     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Rowley JD, Vignon C, Gollin SM, Rosenberg CL, Wyandt HE, Milunsky A: Involvement of MLL in treatment related acute myeloid leukemia in a patient with breast cancer treated on the NSABP-B25 trial: Usefulness of fluorescence in situ hybridization. N Engl J Med 334:601, 1996
2. Thirman MJ, Larson RA: Therapy-related myeloid leukemia. Hematol Oncol Clin North Am 10:293, 1996
3. Pedersen Bjergaard J, Rowley JD: The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation. Blood 83:2780, 1994
4. Pui C-H, Ribeiro RC, Hancock ML, Rivera GK, Evans WE, Raimondi SC, Head DR, Behm FG, Mahmoud MH, Sandlund JT, Crist WM: Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia. N Engl J Med 325:1682, 1991
5. Gill-Super HJ, McCabe NR, Thirman MJ, Larson RA, Le Beau MM, Pedersen-Bjergaard J, Preben P, Diaz MO, Rowley JD: Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topo II. Blood 82:3705, 1993
6. Winick NJ, McKenna RW, Shuster JJ, Schneider NR, Borowitz MJ, Bowman WP, Jacaruso D, Kamen BA, Buchanan GR: Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide. J Clin Oncol 11:209, 1993
7. Felix CA, Winick NJ, Negrini M, Bowman WP, Croce CM, Lange BJ: Common region of ALL-1 gene disrupted in epipodophyllotoxin-related secondary acute myeloid leukemia. Cancer Res 53:2954, 1993
8. Domer PH, Head DR, Renganathan N, Raimondi SC, Yang E, Atlas M: Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topo II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11). Leukemia 9:1305, 1995
9. Roulston D, Anastasi J, Rudinsky R, Nucifora G, Zeleznik-Le J, Rowley JD: Therapy-related acute leukemia associated with t(11q23) after primary acute myeloid leukemia with t(8;21): A report of two cases. Blood 86:3613, 1995
10. Rowley JD, Vignon C, Gollin SM, Rosenberg CL, Wyandt HE, Milunsky A: Chromosome translocations in secondary acute myeloid leukemia. N Engl J Med 334:601, 1996
11. Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ: MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proc Natl Acad Sci USA (in press)
12. Hunger SP, Tkachuk DC, Amylon MD, Link MP, Carroll AJ, Welborn JL, Willman CL, Cleary ML: HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities. Blood 81:3197, 1993
13. Zhang Y, Poetsch M, Weber-Matthiesen K, Rohde K, Winkemann M, Haferlach T, Gassmann W, Ludwiig W-D, Grote W, Loffler H, Schlegelberger B: Secondary acute leukaemias with 11q23 rearrangement: Clinical, cytogenetic, FISH and FICTION studies. Br J Haematol 92:673, 1996
14. Laver JH, Yusuf U, Cantu ES, Barredo JC, Holt LB, Abboud MR: Transient therapy-related myelodysplastic syndrome associated with monosomy 7 and 11q23 translocation. Leukemia 11:448, 1997
15. Rowley JD, Diaz MO, Espinosa R III, Patel YD, van Melle E, Ziemin-van der Poel S, Taillon-Miller P, Lichter P, Evans GA, Kersey JH, Ward DC, Domer PH, Le Beau MM: Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: Identification of 11q23 translocation breakpoints with a yeast artificial chromosome. Proc Natl Acad Sci USA 87:9358, 1990
16. Anastasi J, Vardiman JW, Rudinsky R, Patel M, Nachman JB, Rubin CM, Le Beau MM: Drect correlation of cytogenetic findings with cell morphology by in situ hybridization: An analysis of suspicious cells from bone marrow specimens of two patients completing therapy for lymphoblastic leukemia. Blood 77:2456, 1991
17. Anastasi J, Feng J, Le Beau MM, Larson RA, Rowley JD, Vardiman JW: Cytogenetic clonality in myelodysplatic syndromes studied with fluorescence in situ hybridization: Lineage, response to growth factors, and clone expansion. Blood 81:1580, 1993
18. Pui C-H, Relling MV, Rivera GK, Hancock ML, Raimondi SC, Heslop HE, Santana VM, Ribeiro RC, Sandlund JT, Mahmoud HH, Evans WE, Crist WM, Krance RA: Epipodophyllotoxin-related acute myeloid leukemia: A study of 35 cases. Leukemia 9:1990, 1995
19. Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A, Maseki N, Kaneko Y: Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16)(q23;p13) chromosome translocation. Genes Chromosomes Cancer (in press)
20. Corral J, Lavenir I, Impey H, Warren AJ, Foster A, Larson TA, Bell S, McKenzie ANJ, King G, Rabbitts TH: An MLL-AF9 gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes. Cell 85:853, 1996
21. Borrow J, Stanton VP, Andresen M, Becher R, Behm FG, Chaganti RSK, Civin CI, Disteche C, Dube I, Frischauf AM, Horsman D, Mitelman F, Volinia S, Watmore AE, Housman DE: The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet 14:33, 1996
22. Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RCM, Masuno M, Tommerup N, van Ommen G-JB, Goodman RH, Peters DJM, Breuning MH: Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376:348, 1995
23. Hanslip JI, Swansbury GJ, Pinkerton R, Catovsky D: The translocation t(8;16)(p11;p13) defines an AML subtype with distinct cytology and clinical features. Leuk Lymphoma 6:479, 1992
24. Quesnel B, Kantarjian J, Pedersen-Bjergaard J, Brault P, Estey E, Lai JL, Tilly H, Stoppa AM, Archimbaud E, Harousseau JL, Bauters F, Fenaux P: Therapy-related acute myeloid leukemia with t(8;21), inv(16), and t(8;16): A report on 25 cases and review of the literature. J Clin Oncol 11:2370, 1993
25. Strissel-Broeker PL, Gill-Super HJ, Thirman MJ, Pomykala H, Yonebayashi Y, Tanabe S, Zeleznik-Le NJ, Rowley JD: Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: Correlation with scaffold attachment regions and topo II consensus binding sites. Blood 87:1912, 1996