-
1
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
Luger K, Mader AW, Richmond RK, Sargent DF and Richmond TJ: Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260, 1997.
-
(1997)
Nature
, vol.389
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
3
-
-
43749098985
-
DNA methylation landscapes: Provocative insights from epigenomics
-
Suzuki MM and Bird A: DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 9: 465-476, 2008.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
4
-
-
77149166638
-
The epigenetic landscape of mammary gland development and functional differentiation
-
Rijnkels M, Kabotyanski E, Montazer-Torbati MB, Beauvais CH, Vassetzky Y, Rosen JM and Devinoy E: The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia 15: 85-100, 2010.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 85-100
-
-
Rijnkels, M.1
Kabotyanski, E.2
Montazer-Torbati, M.B.3
Beauvais, C.H.4
Vassetzky, Y.5
Rosen, J.M.6
Devinoy, E.7
-
6
-
-
0024081657
-
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
-
Watt F and Molloy PL: Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev 2: 1136-1143, 1988.
-
(1988)
Genes Dev
, vol.2
, pp. 1136-1143
-
-
Watt, F.1
Molloy, P.L.2
-
7
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN and Bird A: Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393: 386-389, 1998.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
8
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M and Schubeler D: Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 39: 457-466, 2007.
-
(2007)
Nat Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
9
-
-
33847217958
-
A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 11q: Comparison with chromosome 21q
-
Yamada Y, Shirakawa T, Taylor TD, et al: A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 11q: comparison with chromosome 21q. DNA Seq 17: 300-306, 2006.
-
(2006)
DNA Seq
, vol.17
, pp. 300-306
-
-
Yamada, Y.1
Shirakawa, T.2
Taylor, T.D.3
-
10
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T: Chromatin modifications and their function. Cell 128: 693-705, 2007.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
11
-
-
0034644473
-
Signaling to chromatin through histone modifications
-
Cheung P, Allis CD and Sassone-Corsi P: Signaling to chromatin through histone modifications. Cell 103: 263-271, 2000.
-
(2000)
Cell
, vol.103
, pp. 263-271
-
-
Cheung, P.1
Allis, C.D.2
Sassone-Corsi, P.3
-
12
-
-
70449518412
-
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
-
Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR and Price BD: Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat Cell Biol 11: 1376-1382, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1376-1382
-
-
Sun, Y.1
Jiang, X.2
Xu, Y.3
Ayrapetov, M.K.4
Moreau, L.A.5
Whetstine, J.R.6
Price, B.D.7
-
13
-
-
33847070442
-
The role of chromatin during transcription
-
Li B, Carey M and Workman JL: The role of chromatin during transcription. Cell 128: 707-719, 2007.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
14
-
-
79954577502
-
The histone modifications governing TFF1 transcription mediated by estrogen receptor
-
Li Y, Sun L, Zhang Y, et al: The histone modifications governing TFF1 transcription mediated by estrogen receptor. J Biol Chem 286: 13925-13936, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 13925-13936
-
-
Li, Y.1
Sun, L.2
Zhang, Y.3
-
15
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD and Allis CD: The language of covalent histone modifications. Nature 403: 41-45, 2000.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
16
-
-
56949091982
-
MiRNAs, epigenetics, and cancer
-
Rouhi A, Mager DL, Humphries RK and Kuchenbauer F: MiRNAs, epigenetics, and cancer. Mamm Genome 19: 517-525, 2008.
-
(2008)
Mamm Genome
, vol.19
, pp. 517-525
-
-
Rouhi, A.1
Mager, D.L.2
Humphries, R.K.3
Kuchenbauer, F.4
-
17
-
-
0037423845
-
Vertebrate microRNA genes
-
Lim LP, Glasner ME, Yekta S, Burge CB and Bartel DP: Vertebrate microRNA genes. Science 299: 1540, 2003.
-
(2003)
Science
, vol.299
, pp. 1540
-
-
Lim, L.P.1
Glasner, M.E.2
Yekta, S.3
Burge, C.B.4
Bartel, D.P.5
-
20
-
-
78649812261
-
Interplay between microRNAs and the epigenetic machinery: An intricate network
-
Iorio MV, Piovan C and Croce CM: Interplay between microRNAs and the epigenetic machinery: an intricate network. Biochim Biophys Acta 1799: 694-701, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1799
, pp. 694-701
-
-
Iorio, M.V.1
Piovan, C.2
Croce, C.M.3
-
21
-
-
65549083102
-
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
-
Friedman JM, Liang G, Liu CC, et al: The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res 69: 2623-2629, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 2623-2629
-
-
Friedman, J.M.1
Liang, G.2
Liu, C.C.3
-
22
-
-
77953624215
-
+ T cells by directly and indirectly targeting DNA methyltransferase 1
-
+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol 184: 6773-6781, 2010.
-
(2010)
J Immunol
, vol.184
, pp. 6773-6781
-
-
Pan, W.1
Zhu, S.2
Yuan, M.3
-
23
-
-
77956616754
-
Epigenetic control of Hox genes during neurogenesis, development, and disease
-
Barber BA and Rastegar M: Epigenetic control of Hox genes during neurogenesis, development, and disease. Ann Anat 192: 261-274, 2010.
-
(2010)
Ann Anat
, vol.192
, pp. 261-274
-
-
Barber, B.A.1
Rastegar, M.2
-
24
-
-
7944231535
-
The road to Src
-
Martin GS: The road to Src. Oncogene 23: 7910-7917, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 7910-7917
-
-
Martin, G.S.1
-
25
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B and Kinzler KW: Cancer genes and the pathways they control. Nat Med 10: 789-799, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
26
-
-
66149114095
-
Analysis of DNA methylation of multiple genes in microdissected cells from formalin-fixed and paraffin-embedded tissues
-
Dietrich D, Lesche R, Tetzner R, et al: Analysis of DNA methylation of multiple genes in microdissected cells from formalin-fixed and paraffin-embedded tissues. J Histochem Cytochem 57: 477-489, 2009.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 477-489
-
-
Dietrich, D.1
Lesche, R.2
Tetzner, R.3
-
27
-
-
0029922125
-
Imprinting and expression of insulin-like growth factor-II and H19 in normal breast tissue and breast tumor
-
Yballe CM, Vu TH and Hoffman AR: Imprinting and expression of insulin-like growth factor-II and H19 in normal breast tissue and breast tumor. J Clin Endocrinol Metab 81: 1607-1612, 1996.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1607-1612
-
-
Yballe, C.M.1
Vu, T.H.2
Hoffman, A.R.3
-
28
-
-
33646949481
-
DNA hypermethylation in breast cancer and its association with clinicopathological features
-
Li S, Rong M and Iacopetta B: DNA hypermethylation in breast cancer and its association with clinicopathological features. Cancer Lett 237: 272-280, 2006.
-
(2006)
Cancer Lett
, vol.237
, pp. 272-280
-
-
Li, S.1
Rong, M.2
Iacopetta, B.3
-
29
-
-
4143089298
-
Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumors
-
Parrella P, Poeta ML, Gallo AP, et al: Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumors. Clin Cancer Res 10: 5349-5354, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5349-5354
-
-
Parrella, P.1
Poeta, M.L.2
Gallo, A.P.3
-
30
-
-
79957438722
-
Methylated genes in breast cancer: Associations with clinical and histopathological features in a familial breast cancer cohort
-
Swift-Scanlan T, Vang R, Blackford A, Fackler MJ and Sukumar S: Methylated genes in breast cancer: associations with clinical and histopathological features in a familial breast cancer cohort. Cancer Biol Ther 11: 853-865, 2011.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 853-865
-
-
Swift-Scanlan, T.1
Vang, R.2
Blackford, A.3
Fackler, M.J.4
Sukumar, S.5
-
31
-
-
0242677806
-
DNA methylation of RASSF1A, HIN-1, RAR-β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma
-
Fackler MJ, McVeigh M, Evron E, et al: DNA methylation of RASSF1A, HIN-1, RAR-β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Int J Cancer 107: 970-975, 2003.
-
(2003)
Int J Cancer
, vol.107
, pp. 970-975
-
-
Fackler, M.J.1
McVeigh, M.2
Evron, E.3
-
32
-
-
0035321333
-
Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer
-
Yan L, Yang X and Davidson NE: Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer. J Mammary Gland Biol Neoplasia 6: 183-192, 2001.
-
(2001)
J Mammary Gland Biol Neoplasia
, vol.6
, pp. 183-192
-
-
Yan, L.1
Yang, X.2
Davidson, N.E.3
-
33
-
-
42949131685
-
Epigenetic inactivation of microRNA genes in mammary carcinoma
-
In German
-
Lehmann U, Hasemeier B, Romermann D, Muller M, Langer F and Kreipe H: Epigenetic inactivation of microRNA genes in mammary carcinoma. Verh Dtsch Ges Pathol 91: 214-220, 2007 (In German).
-
(2007)
Verh Dtsch Ges Pathol
, vol.91
, pp. 214-220
-
-
Lehmann, U.1
Hasemeier, B.2
Romermann, D.3
Muller, M.4
Langer, F.5
Kreipe, H.6
-
34
-
-
53049099107
-
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity
-
Kapoor-Vazirani P, Kagey JD, Powell DR and Vertino PM: Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. Cancer Res 68: 6810-6821, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 6810-6821
-
-
Kapoor-Vazirani, P.1
Kagey, J.D.2
Powell, D.R.3
Vertino, P.M.4
-
35
-
-
64549090667
-
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells
-
Yang X, Karuturi RK, Sun F, et al: CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. PLoS One 4: e5011, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Yang, X.1
Karuturi, R.K.2
Sun, F.3
-
36
-
-
84862833645
-
Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion
-
Chen J, Luo Q, Yuan Y, et al: Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion. Mol Cell Biol 30: 5621-5635, 2010.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 5621-5635
-
-
Chen, J.1
Luo, Q.2
Yuan, Y.3
-
37
-
-
79956291600
-
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
-
Shi L, Sun L, Li Q, et al: Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci USA 108: 7541-7546, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 7541-7546
-
-
Shi, L.1
Sun, L.2
Li, Q.3
-
38
-
-
68749108259
-
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
-
Wang Y, Zhang H, Chen Y, et al: LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 138: 660-672, 2009.
-
(2009)
Cell
, vol.138
, pp. 660-672
-
-
Wang, Y.1
Zhang, H.2
Chen, Y.3
-
39
-
-
79957894183
-
mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients
-
Sieuwerts AM, Mostert B, Bolt-de Vries J, et al: mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients. Clin Cancer Res 17: 3600-3618, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3600-3618
-
-
Sieuwerts, A.M.1
Mostert, B.2
Bolt-de Vries, J.3
-
40
-
-
77955591555
-
MicroRNAs and their target gene networks in breast cancer
-
O'Day E and Lal A: MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res 12: 201, 2010.
-
(2010)
Breast Cancer Res
, vol.12
, pp. 201
-
-
O'Day, E.1
Lal, A.2
-
41
-
-
36849078711
-
let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, et al: let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131: 1109-1123, 2007.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
-
42
-
-
80054856081
-
miR-21 expression in pregnancy-associated breast cancer: A possible marker of poor prognosis
-
Walter BA, Gomez-Macias G, Valera VA, Sobel M and Merino MJ: miR-21 expression in pregnancy-associated breast cancer: a possible marker of poor prognosis. J Cancer 2: 67-75, 2011.
-
(2011)
J Cancer
, vol.2
, pp. 67-75
-
-
Walter, B.A.1
Gomez-Macias, G.2
Valera, V.A.3
Sobel, M.4
Merino, M.J.5
-
43
-
-
33750376591
-
Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA
-
Hossain A, Kuo MT and Saunders GF: Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA. Mol Cell Biol 26: 8191-8201, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8191-8201
-
-
Hossain, A.1
Kuo, M.T.2
Saunders, G.F.3
-
44
-
-
40249092910
-
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
-
Zhu S, Wu H, Wu F, Nie D, Sheng S and Mo YY: MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18: 350-359, 2008.
-
(2008)
Cell Res
, vol.18
, pp. 350-359
-
-
Zhu, S.1
Wu, H.2
Wu, F.3
Nie, D.4
Sheng, S.5
Mo, Y.Y.6
-
45
-
-
79251600678
-
Genome-wide methylation analysis identifies involvement of TNF-α mediated cancer pathways in prostate cancer
-
Kim SJ, Kelly WK, Fu A, Haines K, Hoffman A, Zheng T and Zhu Y: Genome-wide methylation analysis identifies involvement of TNF-α mediated cancer pathways in prostate cancer. Cancer Lett 302: 47-53, 2011.
-
(2011)
Cancer Lett
, vol.302
, pp. 47-53
-
-
Kim, S.J.1
Kelly, W.K.2
Fu, A.3
Haines, K.4
Hoffman, A.5
Zheng, T.6
Zhu, Y.7
-
46
-
-
0023230209
-
Hypomethylation of DNA in pathological conditions of the human prostate
-
Bedford MT and van Helden PD: Hypomethylation of DNA in pathological conditions of the human prostate. Cancer Res 47: 5274-5276, 1987.
-
(1987)
Cancer Res
, vol.47
, pp. 5274-5276
-
-
Bedford, M.T.1
Van Helden, P.D.2
-
47
-
-
27144437605
-
Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: Prognostic and therapeutic implications
-
Pakneshan P, Szyf M and Rabbani SA: Hypomethylation of urokinase (uPA) promoter in breast and prostate cancer: prognostic and therapeutic implications. Curr Cancer Drug Targets 5: 471-488, 2005.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 471-488
-
-
Pakneshan, P.1
Szyf, M.2
Rabbani, S.A.3
-
48
-
-
0038387946
-
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma
-
Cho B, Lee H, Jeong S, et al: Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. Biochem Biophys Res Commun 307: 52-63, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 52-63
-
-
Cho, B.1
Lee, H.2
Jeong, S.3
-
49
-
-
23844451055
-
Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer
-
Tokizane T, Shiina H, Igawa M, et al: Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer. Clin Cancer Res 11: 5793-5801, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5793-5801
-
-
Tokizane, T.1
Shiina, H.2
Igawa, M.3
-
50
-
-
24744437781
-
Hypomethylation of the XIST gene promoter in prostate cancer
-
Laner T, Schulz WA, Engers R, Muller M and Florl AR: Hypomethylation of the XIST gene promoter in prostate cancer. Oncol Res 15: 257-264, 2005.
-
(2005)
Oncol Res
, vol.15
, pp. 257-264
-
-
Laner, T.1
Schulz, W.A.2
Engers, R.3
Muller, M.4
Florl, A.R.5
-
51
-
-
33847386223
-
Promoter hypermethylation of GSTP1, AR, and 14-3-3σ in serum of prostate cancer patients and its clinical relevance
-
Reibenwein J, Pils D, Horak P, et al: Promoter hypermethylation of GSTP1, AR, and 14-3-3σ in serum of prostate cancer patients and its clinical relevance. Prostate 67: 427-432, 2007.
-
(2007)
Prostate
, vol.67
, pp. 427-432
-
-
Reibenwein, J.1
Pils, D.2
Horak, P.3
-
52
-
-
0037534075
-
Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma
-
Dammann R, Schagdarsurengin U, Liu L, et al: Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. Oncogene 22: 3806-3812, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 3806-3812
-
-
Dammann, R.1
Schagdarsurengin, U.2
Liu, L.3
-
53
-
-
0037738934
-
Hypermethylation of GSTP1, CD44, and E-cadherin genes in prostate cancer among US Blacks and Whites
-
Woodson K, Hayes R, Wideroff L, Villaruz L and Tangrea J: Hypermethylation of GSTP1, CD44, and E-cadherin genes in prostate cancer among US Blacks and Whites. Prostate 55: 199-205, 2003.
-
(2003)
Prostate
, vol.55
, pp. 199-205
-
-
Woodson, K.1
Hayes, R.2
Wideroff, L.3
Villaruz, L.4
Tangrea, J.5
-
54
-
-
70049088266
-
Interest of methylated genes as biomarkers in urothelial cell carcinomas of the urinary tract
-
Phe V, Cussenot O and Roupret M: Interest of methylated genes as biomarkers in urothelial cell carcinomas of the urinary tract. BJU Int 104: 896-901, 2009.
-
(2009)
BJU Int
, vol.104
, pp. 896-901
-
-
Phe, V.1
Cussenot, O.2
Roupret, M.3
-
55
-
-
34547728776
-
Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors
-
Pulukuri SM, Patibandla S, Patel J, Estes N and Rao JS: Epigenetic inactivation of the tissue inhibitor of metalloproteinase-2 (TIMP-2) gene in human prostate tumors. Oncogene 26: 5229-5237, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 5229-5237
-
-
Pulukuri, S.M.1
Patibandla, S.2
Patel, J.3
Estes, N.4
Rao, J.S.5
-
56
-
-
33750435596
-
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer
-
Henrique R, Costa VL, Cerveira N, et al: Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer. J Mol Med 84: 911-918, 2006.
-
(2006)
J Mol Med
, vol.84
, pp. 911-918
-
-
Henrique, R.1
Costa, V.L.2
Cerveira, N.3
-
57
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
Seligson DB, Horvath S, Shi T, Yu H, Tze S, Grunstein M and Kurdistani SK: Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435: 1262-1266, 2005.
-
(2005)
Nature
, vol.435
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
58
-
-
72849148472
-
Global levels of histone modifications predict prostate cancer recurrence
-
Ellinger J, Kahl P, von der Gathen J, et al: Global levels of histone modifications predict prostate cancer recurrence. Prostate 70: 61-69, 2010.
-
(2010)
Prostate
, vol.70
, pp. 61-69
-
-
Ellinger, J.1
Kahl, P.2
Von Der Gathen, J.3
-
59
-
-
77953555473
-
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications
-
Muller I, Wischnewski F, Pantel K and Schwarzenbach H: Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications. BMC Cancer 10: 297, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 297
-
-
Muller, I.1
Wischnewski, F.2
Pantel, K.3
Schwarzenbach, H.4
-
60
-
-
35748937338
-
Integrative genomics analysis reveals silencing of β-adrenergic signaling by polycomb in prostate cancer
-
Yu J, Cao Q, Mehra R, et al: Integrative genomics analysis reveals silencing of β-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 12: 419-431, 2007.
-
(2007)
Cancer Cell
, vol.12
, pp. 419-431
-
-
Yu, J.1
Cao, Q.2
Mehra, R.3
-
61
-
-
79959703562
-
miR 488* inhibits androgen receptor expression in prostate carcinoma cells
-
Sikand K, Slaibi JE, Singh R, Slane SD and Shukla GC: miR 488* inhibits androgen receptor expression in prostate carcinoma cells. Int J Cancer 129: 810-819, 2011.
-
(2011)
Int J Cancer
, vol.129
, pp. 810-819
-
-
Sikand, K.1
Slaibi, J.E.2
Singh, R.3
Slane, S.D.4
Shukla, G.C.5
-
62
-
-
78650117232
-
MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer
-
Majid S, Dar AA, Saini S, et al: MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. Cancer 116: 5637-5649, 2010.
-
(2010)
Cancer
, vol.116
, pp. 5637-5649
-
-
Majid, S.1
Dar, A.A.2
Saini, S.3
-
63
-
-
58149240996
-
The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice
-
Mercatelli N, Coppola V, Bonci D, et al: The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice. PLoS One 3: e4029, 2008.
-
(2008)
PLoS One
, vol.3
-
-
Mercatelli, N.1
Coppola, V.2
Bonci, D.3
-
64
-
-
77956305756
-
MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
-
Dong Q, Meng P, Wang T, et al: MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS One 5: e10147, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Dong, Q.1
Meng, P.2
Wang, T.3
-
65
-
-
79957599227
-
Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT
-
Peng X, Guo W, Liu T, et al: Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One 6: e20341, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Peng, X.1
Guo, W.2
Liu, T.3
-
66
-
-
54449092239
-
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells
-
Fujita Y, Kojima K, Hamada N, et al: Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun 377: 114-119, 2008.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 114-119
-
-
Fujita, Y.1
Kojima, K.2
Hamada, N.3
-
67
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
Lodygin D, Tarasov V, Epanchintsev A, et al: Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7: 2591-2600, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
-
68
-
-
40449131878
-
Loss of mir-146a function in hormone-refractory prostate cancer
-
Lin SL, Chiang A, Chang D and Ying SY: Loss of mir-146a function in hormone-refractory prostate cancer. RNA 14: 417-424, 2008.
-
(2008)
RNA
, vol.14
, pp. 417-424
-
-
Lin, S.L.1
Chiang, A.2
Chang, D.3
Ying, S.Y.4
-
69
-
-
38349135680
-
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
-
Rauch TA, Zhong X, Wu X, et al: High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci USA 105: 252-257, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 252-257
-
-
Rauch, T.A.1
Zhong, X.2
Wu, X.3
-
70
-
-
77949515989
-
Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC
-
Glazer CA, Smith IM, Ochs MF, et al: Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC. PLoS One 4: e8189, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Glazer, C.A.1
Smith, I.M.2
Ochs, M.F.3
-
71
-
-
0028787221
-
CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine
-
Otterson GA, Khleif SN, Chen W, Coxon AB and Kaye FJ: CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2′deoxycytidine. Oncogene 11: 1211-1216, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 1211-1216
-
-
Otterson, G.A.1
Khleif, S.N.2
Chen, W.3
Coxon, A.B.4
Kaye, F.J.5
-
72
-
-
0036682379
-
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors
-
Paz MF, Avila S, Fraga MF, et al: Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer Res 62: 4519-4524, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 4519-4524
-
-
Paz, M.F.1
Avila, S.2
Fraga, M.F.3
-
73
-
-
33846844870
-
Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors
-
Pereira MA, Tao L, Liu Y, Li L, Steele VE and Lubet RA: Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors. Int J Cancer 120: 1150-1153, 2007.
-
(2007)
Int J Cancer
, vol.120
, pp. 1150-1153
-
-
Pereira, M.A.1
Tao, L.2
Liu, Y.3
Li, L.4
Steele, V.E.5
Lubet, R.A.6
-
74
-
-
40449124506
-
Aberrant promoter methylation profile in pleural fluid DNA and clinicopathological factors in patients with non-small cell lung cancer
-
Katayama H, Hiraki A, Fujiwara K, et al: Aberrant promoter methylation profile in pleural fluid DNA and clinicopathological factors in patients with non-small cell lung cancer. Asian Pac J Cancer Prev 8: 221-224, 2007.
-
(2007)
Asian Pac J Cancer Prev
, vol.8
, pp. 221-224
-
-
Katayama, H.1
Hiraki, A.2
Fujiwara, K.3
-
75
-
-
47949123984
-
Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung
-
Licchesi JD, Westra WH, Hooker CM and Herman JG: Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung. Clin Cancer Res 14: 2570-2578, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2570-2578
-
-
Licchesi, J.D.1
Westra, W.H.2
Hooker, C.M.3
Herman, J.G.4
-
76
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, et al: High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837, 2007.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
-
77
-
-
65649142216
-
Global levels of histone modifications predict prognosis in different cancers
-
Seligson DB, Horvath S, McBrian MA, et al: Global levels of histone modifications predict prognosis in different cancers. Am J Pathol 174: 1619-1628, 2009.
-
(2009)
Am J Pathol
, vol.174
, pp. 1619-1628
-
-
Seligson, D.B.1
Horvath, S.2
McBrian, M.A.3
-
78
-
-
68149182343
-
The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence
-
Feng Y, Wang X, Xu L, et al: The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence. FEBS J 276: 4197-4206, 2009.
-
(2009)
FEBS J
, vol.276
, pp. 4197-4206
-
-
Feng, Y.1
Wang, X.2
Xu, L.3
-
79
-
-
13944274117
-
Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer
-
Nonaka D, Fabbri A, Roz L, et al: Reduced FEZ1/LZTS1 expression and outcome prediction in lung cancer. Cancer Res 65: 1207-1212, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 1207-1212
-
-
Nonaka, D.1
Fabbri, A.2
Roz, L.3
-
80
-
-
18544391144
-
MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer
-
Nishioka M, Kohno T, Tani M, et al: MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer. Proc Natl Acad Sci USA 99: 12269-12274, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12269-12274
-
-
Nishioka, M.1
Kohno, T.2
Tani, M.3
-
81
-
-
78049307486
-
H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM
-
Chen MW, Hua KT, Kao HJ, et al: H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM. Cancer Res 70: 7830-7840, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 7830-7840
-
-
Chen, M.W.1
Hua, K.T.2
Kao, H.J.3
-
82
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al: RAS is regulated by the let-7 microRNA family. Cell 120: 635-647, 2005.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
83
-
-
14644398601
-
The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. Elegans
-
Grosshans H, Johnson T, Reinert KL, Gerstein M and Slack FJ: The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev Cell 8: 321-330, 2005.
-
(2005)
Dev Cell
, vol.8
, pp. 321-330
-
-
Grosshans, H.1
Johnson, T.2
Reinert, K.L.3
Gerstein, M.4
Slack, F.J.5
-
84
-
-
38349191617
-
CpG island hypermethylation of tumor suppressor microRNAs in human cancer
-
Lujambio A and Esteller M: CpG island hypermethylation of tumor suppressor microRNAs in human cancer. Cell Cycle 6: 1455-1459, 2007.
-
(2007)
Cell Cycle
, vol.6
, pp. 1455-1459
-
-
Lujambio, A.1
Esteller, M.2
-
85
-
-
41949102707
-
miRiad roles for the miR-17-92 cluster in development and disease
-
Mendell JT: miRiad roles for the miR-17-92 cluster in development and disease. Cell 133: 217-222, 2008.
-
(2008)
Cell
, vol.133
, pp. 217-222
-
-
Mendell, J.T.1
-
86
-
-
79953327117
-
The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: A retrospective analysis of three cohorts
-
Saito M, Schetter AJ, Mollerup S, et al: The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts. Clin Cancer Res 17: 1875-1882, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1875-1882
-
-
Saito, M.1
Schetter, A.J.2
Mollerup, S.3
-
87
-
-
32244444440
-
Regulation of h MSH2 and h MLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1
-
Fang JY, Lu R, Mikovits JA, Cheng ZH, Zhu HY and Chen YX: Regulation of h MSH2 and h MLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1. Cancer Lett 233: 124-130, 2006.
-
(2006)
Cancer Lett
, vol.233
, pp. 124-130
-
-
Fang, J.Y.1
Lu, R.2
Mikovits, J.A.3
Cheng, Z.H.4
Zhu, H.Y.5
Chen, Y.X.6
-
88
-
-
2342504508
-
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
-
Goel A, Arnold CN, Niedzwiecki D, et al: Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res 64: 3014-3021, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3014-3021
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
-
89
-
-
0037438985
-
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers
-
Yuan BZ, Durkin ME and Popescu NC: Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. Cancer Genet Cytogenet 140: 113-117, 2003.
-
(2003)
Cancer Genet Cytogenet
, vol.140
, pp. 113-117
-
-
Yuan, B.Z.1
Durkin, M.E.2
Popescu, N.C.3
-
90
-
-
58249089741
-
Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3
-
Thangaraju M, Carswell KN, Prasad PD and Ganapathy V: Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem J 417: 379-389, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 379-389
-
-
Thangaraju, M.1
Carswell, K.N.2
Prasad, P.D.3
Ganapathy, V.4
-
91
-
-
38949148986
-
HDAC3 overexpression and colon cancer cell proliferation and differentiation
-
Spurling CC, Godman CA, Noonan EJ, Rasmussen TP, Rosenberg DW and Giardina C: HDAC3 overexpression and colon cancer cell proliferation and differentiation. Mol Carcinog 47: 137-147, 2008.
-
(2008)
Mol Carcinog
, vol.47
, pp. 137-147
-
-
Spurling, C.C.1
Godman, C.A.2
Noonan, E.J.3
Rasmussen, T.P.4
Rosenberg, D.W.5
Giardina, C.6
-
92
-
-
54349093531
-
HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling
-
Godman CA, Joshi R, Tierney BR, et al: HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biol Ther 7: 1570-1580, 2008.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1570-1580
-
-
Godman, C.A.1
Joshi, R.2
Tierney, B.R.3
-
93
-
-
79956216777
-
Senescence-associated gene YPEL3 is downregulated in human colon tumors
-
Tuttle R, Simon M, Hitch DC, et al: Senescence-associated gene YPEL3 is downregulated in human colon tumors. Ann Surg Oncol 18: 1791-1796, 2011.
-
(2011)
Ann Surg Oncol
, vol.18
, pp. 1791-1796
-
-
Tuttle, R.1
Simon, M.2
Hitch, D.C.3
-
94
-
-
79953324791
-
Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620
-
Li Q and Chen H: Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620. Clin Exp Metastasis 28: 127-135, 2011.
-
(2011)
Clin Exp Metastasis
, vol.28
, pp. 127-135
-
-
Li, Q.1
Chen, H.2
-
95
-
-
74049138706
-
The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis
-
Menigatti M, Cattaneo E, Sabates-Bellver J, et al: The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis. Mol Cancer 8: 124, 2009.
-
(2009)
Mol Cancer
, vol.8
, pp. 124
-
-
Menigatti, M.1
Cattaneo, E.2
Sabates-Bellver, J.3
-
97
-
-
73549088729
-
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth
-
Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S and Giaccia AJ: Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth. Mol Cell Biol 30: 344-353, 2010.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 344-353
-
-
Krieg, A.J.1
Rankin, E.B.2
Chan, D.3
Razorenova, O.4
Fernandez, S.5
Giaccia, A.J.6
-
98
-
-
74749091103
-
Epigenetic modifications induced by RGC-32 in colon cancer
-
Vlaicu SI, Tegla CA, Cudrici CD, et al: Epigenetic modifications induced by RGC-32 in colon cancer. Exp Mol Pathol 88: 67-76, 2010.
-
(2010)
Exp Mol Pathol
, vol.88
, pp. 67-76
-
-
Vlaicu, S.I.1
Tegla, C.A.2
Cudrici, C.D.3
-
99
-
-
77953308345
-
MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation
-
Yin Q, Wang X, Fewell C, et al: MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. J Virol 84: 6318-6327, 2010.
-
(2010)
J Virol
, vol.84
, pp. 6318-6327
-
-
Yin, Q.1
Wang, X.2
Fewell, C.3
-
100
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, et al: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 17: 211-215, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
-
101
-
-
36348994146
-
Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells
-
Shi B, Sepp-Lorenzino L, Prisco M, Linsley P, deAngelis T and Baserga R: Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem 282: 32582-32590, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 32582-32590
-
-
Shi, B.1
Sepp-Lorenzino, L.2
Prisco, M.3
Linsley, P.4
DeAngelis, T.5
Baserga, R.6
-
102
-
-
67349254469
-
MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
-
Li T, Li D, Sha J, Sun P and Huang Y: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun 383: 280-285, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 280-285
-
-
Li, T.1
Li, D.2
Sha, J.3
Sun, P.4
Huang, Y.5
-
103
-
-
79961189334
-
MicroRNA-345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer
-
Tang JT, Wang JL, Du W, et al: MicroRNA-345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. Carcinogenesis 32: 1207-1215, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1207-1215
-
-
Tang, J.T.1
Wang, J.L.2
Du, W.3
-
104
-
-
80054046712
-
Global histone H4K20 trimethylation predicts cancer-specific survival in patients with muscle-invasive bladder cancer
-
Schneider AC, Heukamp LC, Rogenhofer S, et al: Global histone H4K20 trimethylation predicts cancer-specific survival in patients with muscle-invasive bladder cancer. BJU Int 1082: E290-E296, 2011.
-
(2011)
BJU Int
, vol.1082
-
-
Schneider, A.C.1
Heukamp, L.C.2
Rogenhofer, S.3
-
105
-
-
65949086183
-
Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome
-
Elsheikh SE, Green AR, Rakha EA, et al: Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome. Cancer Res 69: 3802-3809, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 3802-3809
-
-
Elsheikh, S.E.1
Green, A.R.2
Rakha, E.A.3
-
106
-
-
58149329023
-
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer
-
Van Den Broeck A, Brambilla E, Moro-Sibilot D, et al: Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin Cancer Res 14: 7237-7245, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7237-7245
-
-
Van Den Broeck, A.1
Brambilla, E.2
Moro-Sibilot, D.3
-
107
-
-
78049518884
-
Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma
-
Ellinger J, Kahl P, Mertens C, et al: Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma. Int J Cancer 127: 2360-2366, 2010.
-
(2010)
Int J Cancer
, vol.127
, pp. 2360-2366
-
-
Ellinger, J.1
Kahl, P.2
Mertens, C.3
-
108
-
-
61849178049
-
Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis
-
Ke XS, Qu Y, Rostad K, et al: Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLoS One 4: e4687, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Ke, X.S.1
Qu, Y.2
Rostad, K.3
-
109
-
-
78149440189
-
Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus
-
Li Q, Wang X, Lu Z, et al: Polycomb CBX7 directly controls trimethylation of histone H3 at lysine 9 at the p16 locus. PLoS One 5: e13732, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Li, Q.1
Wang, X.2
Lu, Z.3
-
110
-
-
48649100069
-
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells
-
McGarvey KM, Van Neste L, Cope L, et al: Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells. Cancer Res 68: 5753-5759, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 5753-5759
-
-
McGarvey, K.M.1
Van Neste, L.2
Cope, L.3
-
111
-
-
50249175130
-
Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers
-
Wei Y, Xia W, Zhang Z, et al: Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers. Mol Carcinog 47: 701-706, 2008.
-
(2008)
Mol Carcinog
, vol.47
, pp. 701-706
-
-
Wei, Y.1
Xia, W.2
Zhang, Z.3
-
112
-
-
33846026708
-
Methyl deficiency, alterations in global histone modifications, and carcinogenesis
-
Pogribny IP, Tryndyak VP, Muskhelishvili L, Rusyn I and Ross SA: Methyl deficiency, alterations in global histone modifications, and carcinogenesis. J Nutr 137: 216S-222S, 2007.
-
(2007)
J Nutr
, vol.137
-
-
Pogribny, I.P.1
Tryndyak, V.P.2
Muskhelishvili, L.3
Rusyn, I.4
Ross, S.A.5
-
113
-
-
1642296732
-
ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia
-
Canaani E, Nakamura T, Rozovskaia T, Smith ST, Mori T, Croce CM and Mazo A: ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia. Br J Cancer 90: 756-760, 2004.
-
(2004)
Br J Cancer
, vol.90
, pp. 756-760
-
-
Canaani, E.1
Nakamura, T.2
Rozovskaia, T.3
Smith, S.T.4
Mori, T.5
Croce, C.M.6
Mazo, A.7
-
114
-
-
77956944025
-
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
-
Liu H, Takeda S, Kumar R, et al: Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature 467: 343-346, 2010.
-
(2010)
Nature
, vol.467
, pp. 343-346
-
-
Liu, H.1
Takeda, S.2
Kumar, R.3
-
115
-
-
33646474127
-
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis
-
Scacheri PC, Davis S, Odom DT, et al: Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. PLoS Genet 2: e51, 2006.
-
(2006)
PLoS Genet
, vol.2
-
-
Scacheri, P.C.1
Davis, S.2
Odom, D.T.3
-
116
-
-
77954875340
-
Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice
-
Seigne C, Fontaniere S, Carreira C, et al: Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice. BMC Cancer 10: 395, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 395
-
-
Seigne, C.1
Fontaniere, S.2
Carreira, C.3
-
117
-
-
77957557698
-
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by menin
-
Feng ZJ, Gao SB, Wu Y, Xu XF, Hua X and Jin GH: Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by menin. Oncogene 29: 5416-5426, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 5416-5426
-
-
Feng, Z.J.1
Gao, S.B.2
Wu, Y.3
Xu, X.F.4
Hua, X.5
Jin, G.H.6
-
118
-
-
0034917248
-
ASH2L: Alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines
-
Wang J, Zhou Y, Yin B, et al: ASH2L: alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines. J Mol Med 79: 399-405, 2001.
-
(2001)
J Mol Med
, vol.79
, pp. 399-405
-
-
Wang, J.1
Zhou, Y.2
Yin, B.3
-
119
-
-
73749085827
-
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1
-
Magerl C, Ellinger J, Braunschweig T, et al: H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1. Hum Pathol 41: 181-189, 2010.
-
(2010)
Hum Pathol
, vol.41
, pp. 181-189
-
-
Magerl, C.1
Ellinger, J.2
Braunschweig, T.3
-
120
-
-
79959875910
-
DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer
-
Kobayashi Y, Absher DM, Gulzar ZG, et al: DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer. Genome Res 21: 1017-1027, 2011.
-
(2011)
Genome Res
, vol.21
, pp. 1017-1027
-
-
Kobayashi, Y.1
Absher, D.M.2
Gulzar, Z.G.3
-
121
-
-
79955513100
-
Aberrations of EZH2 in cancer
-
Chase A and Cross NC: Aberrations of EZH2 in cancer. Clin Cancer Res 17: 2613-2618, 2011.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2613-2618
-
-
Chase, A.1
Cross, N.C.2
-
122
-
-
78650062951
-
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
-
Velichutina I, Shaknovich R, Geng H, Johnson NA, Gascoyne RD, Melnick AM and Elemento O: EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis. Blood 116: 5247-5255, 2010.
-
(2010)
Blood
, vol.116
, pp. 5247-5255
-
-
Velichutina, I.1
Shaknovich, R.2
Geng, H.3
Johnson, N.A.4
Gascoyne, R.D.5
Melnick, A.M.6
Elemento, O.7
-
123
-
-
79951844951
-
Gastrin-releasing peptide signaling alters colon cancer invasiveness via heterochromatin protein 1Hsß
-
Tell R, Rivera CA, Eskra J, Taglia LN, Blunier A, Wang QT and Benya RV: Gastrin-releasing peptide signaling alters colon cancer invasiveness via heterochromatin protein 1Hsß. Am J Pathol 178: 672-678, 2011.
-
(2011)
Am J Pathol
, vol.178
, pp. 672-678
-
-
Tell, R.1
Rivera, C.A.2
Eskra, J.3
Taglia, L.N.4
Blunier, A.5
Wang, Q.T.6
Benya, R.V.7
-
124
-
-
38749095527
-
Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer
-
Xi Y, Formentini A, Nakajima G, Kornmann M and Ju J: Validation of biomarkers associated with 5-fluorouracil and thymidylate synthase in colorectal cancer. Oncol Rep 19: 257-262, 2008.
-
(2008)
Oncol Rep
, vol.19
, pp. 257-262
-
-
Xi, Y.1
Formentini, A.2
Nakajima, G.3
Kornmann, M.4
Ju, J.5
-
125
-
-
34248190797
-
SMYD3 tandem repeats polymorphism is not associated with the occurrence and metastasis of hepatocellular carcinoma in a Chinese population
-
Wang XQ, Miao X, Cai Q, Garcia-Barcelo MM and Fan ST: SMYD3 tandem repeats polymorphism is not associated with the occurrence and metastasis of hepatocellular carcinoma in a Chinese population. Exp Oncol 29: 71-73, 2007.
-
(2007)
Exp Oncol
, vol.29
, pp. 71-73
-
-
Wang, X.Q.1
Miao, X.2
Cai, Q.3
Garcia-Barcelo, M.M.4
Fan, S.T.5
-
126
-
-
33644845731
-
Accumulation of DNA methylation is associated with tumor stage in gastric cancer
-
Oue N, Mitani Y, Motoshita J, et al: Accumulation of DNA methylation is associated with tumor stage in gastric cancer. Cancer 106: 1250-1259, 2006.
-
(2006)
Cancer
, vol.106
, pp. 1250-1259
-
-
Oue, N.1
Mitani, Y.2
Motoshita, J.3
-
127
-
-
0035937337
-
Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma
-
Fang W, Piao Z, Buyse IM, Simon D, Sheu JC, Perucho M and Huang S: Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma. Br J Cancer 84: 743-747, 2001.
-
(2001)
Br J Cancer
, vol.84
, pp. 743-747
-
-
Fang, W.1
Piao, Z.2
Buyse, I.M.3
Simon, D.4
Sheu, J.C.5
Perucho, M.6
Huang, S.7
-
128
-
-
60549092281
-
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line
-
Zhao Q, Caballero OL, Levy S, et al: Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line. Proc Natl Acad Sci USA 106: 1886-1891, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1886-1891
-
-
Zhao, Q.1
Caballero, O.L.2
Levy, S.3
-
129
-
-
78049275346
-
Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function
-
Lucio-Eterovic AK, Singh MM, Gardner JE, Veerappan CS, Rice JC and Carpenter PB: Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function. Proc Natl Acad Sci USA 107: 16952-16957, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16952-16957
-
-
Lucio-Eterovic, A.K.1
Singh, M.M.2
Gardner, J.E.3
Veerappan, C.S.4
Rice, J.C.5
Carpenter, P.B.6
-
130
-
-
76049084596
-
Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma
-
Berdasco M, Ropero S, Setien F, et al: Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma. Proc Natl Acad Sci USA 106: 21830-21835, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21830-21835
-
-
Berdasco, M.1
Ropero, S.2
Setien, F.3
-
131
-
-
67650461956
-
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
-
Nimura K, Ura K, Shiratori H, Ikawa M, Okabe M, Schwartz RJ and Kaneda Y: A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature 460: 287-291, 2009.
-
(2009)
Nature
, vol.460
, pp. 287-291
-
-
Nimura, K.1
Ura, K.2
Shiratori, H.3
Ikawa, M.4
Okabe, M.5
Schwartz, R.J.6
Kaneda, Y.7
-
132
-
-
64549161949
-
NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes
-
Taketani T, Taki T, Nakamura H, Taniwaki M, Masuda J and Hayashi Y: NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes. Cancer Genet Cytogenet 190: 108-112, 2009.
-
(2009)
Cancer Genet Cytogenet
, vol.190
, pp. 108-112
-
-
Taketani, T.1
Taki, T.2
Nakamura, H.3
Taniwaki, M.4
Masuda, J.5
Hayashi, Y.6
-
133
-
-
79959272481
-
Cancers and the NSD family of histone lysine methyltransferases
-
Morishita M and di Luccio E: Cancers and the NSD family of histone lysine methyltransferases. Biochim Biophys Acta 1816: 158-163, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1816
, pp. 158-163
-
-
Morishita, M.1
Di Luccio, E.2
-
134
-
-
56649103900
-
Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells
-
Watanabe H, Soejima K, Yasuda H, et al: Deregulation of histone lysine methyltransferases contributes to oncogenic transformation of human bronchoepithelial cells. Cancer Cell Int 8: 15, 2008.
-
(2008)
Cancer Cell Int
, vol.8
, pp. 15
-
-
Watanabe, H.1
Soejima, K.2
Yasuda, H.3
-
135
-
-
77952301615
-
Genetic alterations and changes in expression of histone demethylases in prostate cancer
-
Visakorpi T, Suikki HE, Kujala PM, Tammela TLJ, van Weerden WM and Vessella RL: Genetic alterations and changes in expression of histone demethylases in prostate cancer. Prostate 70: 889-898, 2010.
-
(2010)
Prostate
, vol.70
, pp. 889-898
-
-
Visakorpi, T.1
Suikki, H.E.2
Kujala, P.M.3
Tammela, T.L.J.4
Van Weerden, W.M.5
Vessella, R.L.6
-
136
-
-
79951855952
-
Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly
-
Fukuda T, Tokunaga A, Sakamoto R and Yoshida N: Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly. Mol Cell Neurosci 46: 614-624, 2011.
-
(2011)
Mol Cell Neurosci
, vol.46
, pp. 614-624
-
-
Fukuda, T.1
Tokunaga, A.2
Sakamoto, R.3
Yoshida, N.4
-
137
-
-
58149198591
-
Mucosa-associated lymphoid tissue lymphoma: Novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3
-
Vinatzer U, Gollinger M, Mullauer L, Raderer M, Chott A and Streubel B: Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3. Clin Cancer Res 14: 6426-6431, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6426-6431
-
-
Vinatzer, U.1
Gollinger, M.2
Mullauer, L.3
Raderer, M.4
Chott, A.5
Streubel, B.6
-
138
-
-
0034282790
-
Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines
-
Yang ZQ, Imoto I, Fukuda Y, et al: Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. Cancer Res 60: 4735-4739, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 4735-4739
-
-
Yang, Z.Q.1
Imoto, I.2
Fukuda, Y.3
-
139
-
-
77449088946
-
The histone demethylase RBP2 is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells
-
Zeng J, Ge Z, Wang L, et al: The histone demethylase RBP2 is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells. Gastroenterology 138: 981-992, 2010.
-
(2010)
Gastroenterology
, vol.138
, pp. 981-992
-
-
Zeng, J.1
Ge, Z.2
Wang, L.3
-
140
-
-
79958822224
-
Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: Implications for adoptive immunotherapy of cancer
-
Rao M, Chinnasamy N, Hong JA, et al: Inhibition of histone lysine methylation enhances cancer-testis antigen expression in lung cancer cells: implications for adoptive immunotherapy of cancer. Cancer Res 71: 4192-4204, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 4192-4204
-
-
Rao, M.1
Chinnasamy, N.2
Hong, J.A.3
-
141
-
-
77957158585
-
A panel of cancer-testis genes exhibiting broad-spectrum expression in haematological malignancies
-
Liggins AP, Lim SH, Soilleux EJ, Pulford K and Banham AH: A panel of cancer-testis genes exhibiting broad-spectrum expression in haematological malignancies. Cancer Immun 10: 8, 2010.
-
(2010)
Cancer Immun
, vol.10
, pp. 8
-
-
Liggins, A.P.1
Lim, S.H.2
Soilleux, E.J.3
Pulford, K.4
Banham, A.H.5
-
142
-
-
80053534236
-
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A
-
Jankowska A, Makishima H, Tiu RV, et al: Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. Blood 116: 268-269, 2010.
-
(2010)
Blood
, vol.116
, pp. 268-269
-
-
Jankowska, A.1
Makishima, H.2
Tiu, R.V.3
-
143
-
-
35348826654
-
JMJD3 is a histone H3K27 demethylase
-
Xiang Y, Zhu Z, Han G, Lin H, Xu L and Chen CD: JMJD3 is a histone H3K27 demethylase. Cell Res 17: 850-857, 2007.
-
(2007)
Cell Res
, vol.17
, pp. 850-857
-
-
Xiang, Y.1
Zhu, Z.2
Han, G.3
Lin, H.4
Xu, L.5
Chen, C.D.6
|