Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint

Nature

Volumn 467, Issue 7313, 2010, Pages 343-346

  Liu, Han ^a   Takeda, Shugaku ^a   Kumar, Rakesh ^b   Westergard, Todd D ^a   Brown, Eric J ^b   Pandita, Tej K ^b   Cheng, Emily H Y ^a   Hsieh, James J D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; HISTONE LYSINE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; SERINE; UBIQUITIN PROTEIN LIGASE E3; ATM PROTEIN; ATR PROTEIN, MOUSE; CDC45 PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHROMATIN; HISTONE; LYSINE; MLL PROTEIN, HUMAN; PHOSPHOSERINE; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; S PHASE KINASE ASSOCIATED PROTEIN;

CANCER; CHROMOSOME; CYTOLOGY; DNA; GENOME; GENOTOXICITY; MAMMAL;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE S PHASE; CELL STRESS; CHROMATIN; CONTROLLED STUDY; DEREGULATION; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; EMBRYO; ENZYME INHIBITION; ENZYME MECHANISM; FIBROBLAST; GENOTOXICITY; HUMAN; HUMAN CELL; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RADIOSENSITIVITY; WILD TYPE; ANIMAL; CELL LINE; CHEMISTRY; DEFICIENCY; DOMINANT GENE; GENE TRANSLOCATION; GENETICS; GENOMIC INSTABILITY; LEUKEMIA; METABOLISM; METHYLATION; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ALLELES; ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CHROMATIN; DNA DAMAGE; DNA REPLICATION; GENES, DOMINANT; GENOMIC INSTABILITY; HISTONES; HUMANS; LEUKEMIA; LYSINE; METHYLATION; MICE; MYELOID PROGENITOR CELLS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; S PHASE; S-PHASE KINASE-ASSOCIATED PROTEINS; SIGNAL TRANSDUCTION; TRANSLOCATION, GENETIC; ATAXIA TELANGIECTASIA MUTATED PROTEINS;

MAMMALIA; MURINAE;

EID: 77956944025     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09350     Document Type: Article

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