Genetic alterations and changes in expression of histone demethylases in prostate cancer

Prostate

Volumn 70, Issue 8, 2010, Pages 889-898

  Suikki, Hanna E ^a   Kujala, Paula M ^a   Tammela, Teuvo L J ^a   Van Weerden, Wytske M ^b   Vessella, Robert L ^c,d   Visakorpi, Tapio ^a  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d VA Puget Sound   (United States)

Author keywords

AOF2; JMJD1A; JMJD2C; Methylation; Prostatic neoplasia

Indexed keywords

MESSENGER RNA; HISTONE DEMETHYLASE;

ARTICLE; CANCER GROWTH; CANCER SURVIVAL; CASTRATION; GENE AMPLIFIED IN SQUAMOUS CELL CARCINOMA 1; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GLEASON SCORE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; JMJC CONTANING H3K9 DEMTHYLASE GENE; LYSINE SPECIFIC DEMETHYLASE 1 GENE; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATECTOMY; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; ADENOCARCINOMA; CYTOLOGY; DISEASE COURSE; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MUTATION; NONPARAMETRIC TEST; PROSTATE; PROSTATE TUMOR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; TUMOR CELL LINE;

ADENOCARCINOMA; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE PROGRESSION; GENETIC PREDISPOSITION TO DISEASE; HISTONE DEMETHYLASES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATE; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC; TISSUE ARRAY ANALYSIS;

EID: 77952301615     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21123     Document Type: Article

References (44)

1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics. CA Cancer J Clin 2007;57:43-66.
2. Klotz L. Hormone therapy for patients with prostate carcinoma. Cancer 2000;88(12 Suppl.):3009-3014. (Pubitemid 30413184)
3. Kyprianou N, English HF, Isaacs JT. Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. Cancer Res 1990;50:3748-3753. (Pubitemid 20194126)
4. Westlin P, Stattin P, Damper JE, Bergh A. Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors. Am J Pathol 1995;146:1368-1375.
5. Linja MJ, Visakorpi T. Alterations of androgen receptor in prostate cancer. J Steroid Biochem Mol Biol 2004;92:255-264. (Pubitemid 40128246)
6. Visakorpi T, Hyytinen E, Koivisto P, Tanner M, Keinänen R, Palmberg C, Palotie A, Tammela T, Isola J, Kallioniemi O-P. In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 1995;9:401-406.
7. Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004;10: 33-39. (Pubitemid 38524696)
8. Tapling ME, Bubley GJ, Shuster TD, Franz ME, Spooner AE, Ogata GK, Keer HN, Balk SP. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med 1995;322:1393-1398.
9. Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, Ettinger SL, Gleave ME, Nelson CC. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008;68:6407-6415.
10. Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS. Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth. Cancer Res 2008;68:4447-4454.
11. Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung H-J, Brodie AMH, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res 2009;69:2305-2313.
12. Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res 2008;68:5469-5477.
13. Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, Han M, Partin AW, Vessella RL, Isaacs WB, Bova GS, Luo J. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 2009;69:16-22.
14. Heinlein CA, Chang C. Androgen receptor (AR) coregulators: An overview. Endocr Rev 2002;23:175-200.
15. Vaquero A, Loyola A, Reinberg D. 2003; The constantly changing face of chromatin. Sci Aging Knowledge Environ V 14:RE4.
16. Fiscle W, Wang Y, Allis CD. Histone and chromatin cross talk. Curr Opin Cell Biol 2003;15:172-183.
17. Peterson CL, Laniel MA. Histones and histone modifications. Curr Biol 2004;14:R546-R551.
18. Margueron R, Trojer P, Reinberg D. The key to development: Interpreting the histone code? Curr Opin Genet Dev 2005;15: 163-176.
19. Trojer P, Reinberg D. Histone lysine demethylases and their impact on epigenetics. Cell 2006;125:213-217.
20. Shi Y. Histone lysine demethylases: Emerging roles in development, physiology and disease. Nature Rev Genet 2007;8:829-833. (Pubitemid 47609092)
21. Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004;119:941-953. (Pubitemid 40037608)
22. Forneris F, Binda C, Vanoni MA, Battaglioli E, Mattevi A. Human histone demethylase LSD1 reads the histone code. J Biol Chem 2005;280:41360-41365. (Pubitemid 41832193)
23. Mezger E, Wissmann M, Schüle R. Histone demethylation and androgen-dependent transcription. Curr Opin Genet Dev 2006; 16:513-517.
24. Forneris F, Binda C, Battaglioli E, Mattevi A. LSD1: Oxidative chemistry for multifaceted functions in chromatin regulation. Trends Biochem Sci 2008;3:181-189.
25. Wysocka J, Milne TA, Allis CD. Taking LSD1 to a new high. Cell 2005;122:654-658.
26. Shi Y-J, Matson C, Lan F, Iwase S, Baba T, Shi Y. Regulation of LSD1 histone demethylase activity by its associated factors. Mol Cell 2005;19:857-864. (Pubitemid 41316679)
27. Forneris F, Binda C, Dall Aglio, A, Fraaije MW, Battaglioli E, Mattevi A. A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1. J Biol Chem 2006; 281:35289-35295. (Pubitemid 46036567)
28. Lee MG, Wynder C, Bochar DA, Hakimi M-A, Cooch N, Shiekhattar R. Functional interplay between histone demethylase and deacetylase enzymes. Mol Cell Biol 2006;26:6395-6402.
29. Mezker E, Wissmann M, Yin N, Müller JM, Schneider R, Peters AHFM, Günther T, Buettner R, Schüle R. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature 2005;437:436-439.
30. Kahl P, Gullotti L, Heukamp LC, Wolf S, Friedrichs N, Vorreuther R, Solleder G, Bastian PJ, Ellinger J, Metzger E, Schüle R, Buettner R. Androgen receptor coactivators lysine-specific histone demethylase 1 and four and half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res 2006;66:11341-11347.
31. Yamane K, Toumazou C, Tsukada Y-I, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006;125:483-495.
32. Yang Z-Q, Imoto I, Fukuda Y, Pimkhaokham A, Shimada Y, Imamura M, Sugano S, Nakamura Y, Inazawa J. Identification of a novel gene, GASC1, within an amplicon at 9p. 23-24. frequently detected in esophageal cancer cell lines. Cancer Res 2000;60:4735-4739.
33. Shin S, Janknecht XX〈AUTHOR: Please provide initials for author Janknecht in reference [33].〉. Diversity within the JMJD2 histone demethylase family. Biochem Biophy Res Commun 2007;353:973-977.
34. Loh Y-H, Zhang W, Chen X, George J, Ng H-H. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 2007;21:2545-2557.
35. Cloos PAC, Christensen J, Agger K, Maiolica A, Rappsilber J, Antal T, Hansen KH, Helin K. The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 2006;442:307-311. (Pubitemid 44114906)
36. Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Mezger E, Schüle R. Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol 2007;9:347-353.
37. Linja MJ, Porkka KP, Kang Z, Savinainen KJ, Jänne OA, Tammela TLJ, Vessella RL, Palvimo JJ, Visakorpi T. Expression of androgen receptor coregulators in prostate cancer. Clin Cancer Res 2004;10:1032-1040. (Pubitemid 38202234)
38. Mäki HE, Waltering KK, Wallén MJ, Martikainen PM, Tammela TLJ, van Weerden WM, Vessella RL, Visakorpi T. Screening of genetic, expression alterations of SRC1 gene in prostate cancer. Prostate 2006;66:1391-1398. (Pubitemid 44350364)
39. Mäki HE, Saramäki OR, Shatkina L, Martikainen PM, Tammela TLJ, van Weerden WM, Vessella RL, Cato ACB, Visakorpi T. Overexpression and gene amplification of Bag-1l in hormonerefractory prostate cancer. J Pathol 2007;212:395-401. (Pubitemid 47099016)
40. Laitinen S, Martikainen PM, Tolonen T, Isola J, Tammela TLJ, Visakorpi T. EZH2, Ki-67, and MCM7 are prognostic markers in prostatectomy treated patients. Int J Cancer 2008;122:595-602. (Pubitemid 350308951)
41. Van Weerden WM, de Riddder CM, Verdaasdonk CL, Romijn JC, van der Kwast TH, Schroder FH, van Steenbrugge GJ. Development of seven new human prostate tumor xenograft models and their histopathological characterization. Am J Pathol 1996;149:1055-1062.
42. van Weerden WM, Bangma C, de Wit R. Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer. Br J Cancer 2009;100: 13-18.
43. Laitinen S, Karhu R, Sawyers CL, Vessella RL, Visakorpi T. Chromosomal aberrations in prostate cancer xenografts detected by comparative genomic hybridization. Genes Chrom Cancer 2002;35:66-73. (Pubitemid 34847870)
44. Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa- Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O. Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues. Genome Biol 2008;9:R139.