The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence

FEBS Journal

Volumn 276, Issue 15, 2009, Pages 4197-4206

  Lu, Jun ^a   Feng, Yunpeng ^a   Wang, Xiuli ^a   Xu, Liang ^a   Pan, Hong ^a   Zhu, Shan ^a   Liang, Qian ^a   Huang, Baiqu ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Histone deacetylase 3 (HDAC3); Histone deacetylase 4 (HDAC4); P16; Senescence; ZBP 89

Indexed keywords

BETA GALACTOSIDASE; HISTONE; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 4; PROTEIN P16; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZBP 89; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MODIFICATION; RNA INTERFERENCE; SENESCENCE;

APOPTOSIS; BETA-GALACTOSIDASE; CELL AGING; CELL DIVISION; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; KINETICS; LUNG NEOPLASMS; NEOPLASM PROTEINS; TRANSCRIPTION FACTORS;

EID: 68149182343     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07128.x     Document Type: Article

References (29)

1. Bai L Merchant JL (2000) Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cells. J Biol Chem 275, 30725 30733.
2. Bai L Merchant JL (2001) ZBP-89 promotes growth arrest through stabilization of p53. Mol Cell Biol 21, 4670 4683.
3. Wu Y, Zhang X, Salmon M Zehner ZE (2007) The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression. Genes Cells 12, 905 918.
4. Merchant JL, Iyer GR, Taylor BR, Kitchen JR, Mortensen ER, Wang Z, Flintoft RJ, Michel JB Bassel-Duby R (1996) ZBP-89, a Kruppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter. Mol Cell Biol 16, 6644 6653.
5. Cheng PY, Kagawa N, Takahashi Y Waterman MR (2000) Three zinc finger nuclear proteins, Sp1, Sp3, and a ZBP-89 homologue, bind to the cyclic adenosine monophosphate-responsive sequence of the bovine adrenodoxin gene and regulate transcription. Biochemistry 39, 4347 4357.
6. Law GL, Itoh H, Law DJ, Mize GJ, Merchant JL Morris DR (1998) Transcription factor ZBP-89 regulates the activity of the ornithine decarboxylase promoter. J Biol Chem 273, 19955 19964.
7. Zhang X, Diab IH Zehner ZE (2003) ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1. Nucleic Acids Res 31, 2900 2914. (Pubitemid 37442134)
8. Ajamian F, Salminen A Reeben M (2004) Selective regulation of class I and class II histone deacetylase expression by inhibitors of histone deacetylases in cultured mouse neural cells. Neurosci Lett 365, 64 68.
9. Barnes PJ, Adcock IM Ito K (2005) Histone acetylation and deacetylation: importance in inflammatory lung diseases. Eur Respir J 25, 552 563. (Pubitemid 40331188)
10. Sherr CJ Roberts JM (1999) CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13, 1501 1512.
11. Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G Hara E (2001) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature 409, 1067 1070.
12. Gizard F, Amant C, Barbier O, Bellosta S, Robillard R, Percevault F, Sevestre H, Krimpenfort P, Corsini A, Rochette J et al. (2005) PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a. J Clin Invest 115, 3228 3238.
13. Xu HJ, Zhou Y, Ji W, Perng GS, Kruzelock R, Kong CT, Bast RC, Mills GB, Li J Hu SX (1997) Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition. Oncogene 15, 2589 2596.
14. Wang X, Pan L, Feng Y, Wang Y, Han Q, Han L, Han S, Guo J, Huang B Lu J (2008) p300 plays a role in p16(INK4a) expression and cell cycle arrest. Oncogene 27, 1894 1904.
15. Bai L Merchant JL (2003) Transcription factor ZBP-89 is required for STAT1 constitutive expression. Nucleic Acids Res 31, 7264 7270.
16. Feo S, Antona V, Barbieri G, Passantino R, Cali L Giallongo A (1995) Transcription of the human beta enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors. Mol Cell Biol 15, 5991 6002.
17. Passantino R, Antona V, Barbieri G, Rubino P, Melchionna R, Cossu G, Feo S Giallongo A (1998) Negative regulation of beta enolase gene transcription in embryonic muscle is dependent upon a zinc finger factor that binds to the G-rich box within the muscle-specific enhancer. J Biol Chem 273, 484 494.
18. Hasegawa T, Takeuchi A, Miyaishi O, Isobe K de Crombrugghe B (1997) Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. J Biol Chem 272, 4915 4923.
19. Brown JP, Wei W Sedivy JM (1997) Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277, 831 834.
20. Herbig U, Jobling WA, Chen BP, Chen DJ Sedivy JM (2004) Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell 14, 501 513.
21. Laherty CD, Yang WM, Sun JM, Davie JR, Seto E Eisenman RN (1997) Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89, 349 356.
22. Mal A, Sturniolo M, Schiltz RL, Ghosh MK Harter ML (2001) A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program. EMBO J 20, 1739 1753.
23. Yang WM, Inouye C, Zeng Y, Bearss D Seto E (1996) Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc Natl Acad Sci USA 93, 12845 12850.
24. Han S, Lu J, Zhang Y, Cheng C, Han L, Wang X, Li L, Liu C Huang B (2006) Recruitment of histone deacetylase 4 by transcription factors represses interleukin-5 transcription. Biochem J 400, 439 448. (Pubitemid 44974455)
25. Weiss C, Schneider S, Wagner EF, Zhang X, Seto E Bohmann D (2003) JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. EMBO J 22, 3686 3695.
26. Livak KJ Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402 408.
27. Lu J, Sun H, Wang X, Liu C, Xu X, Li F Huang B (2005) Interleukin-12 p40 promoter activity is regulated by the reversible acetylation mediated by HDAC1 and p300. Cytokine 31, 46 51.
28. Kondo Y, Shen L Issa JP (2003) Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol 23, 206 215.
29. Sui G, elAffar B, Shi Y, Brignone C, Wall NR, Yin P, Donohoe M, Luke MP, Calvo D, Grossman SR et al. (2004) Yin Yang 1 is a negative regulator of p53. Cell 117, 859 872.