메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Differential responses of hepatic endoplasmic reticulum stress and inflammation in diet-induced obese rats with high-fat diet rich in lard oil or soybean oil

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INSULIN; LARD; LIPID; MESSENGER RNA; OSTEOPONTIN; PROTEIN IRE1; PROTEIN KINASE R LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN SERINE THREONINE KINASE; SATURATED FATTY ACID; SOYBEAN OIL; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

EID: 84892427081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078620     Document Type: Article
Times cited : (36)

References (70)
  • 2
    • 33747587290 scopus 로고    scopus 로고
    • Overweight and obesity in China
    • Wu Y (2006) Overweight and obesity in China. BMJ 333: 362-363.
    • (2006) BMJ , vol.333 , pp. 362-363
    • Wu, Y.1
  • 4
    • 33846829811 scopus 로고    scopus 로고
    • Abdominal obesity: Role in the pathophysiology of metabolic disease and cardiovascular risk
    • discussion S29-32
    • Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, et al. (2007) Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. The American journal of medicine 120: S3-8; discussion S29-32.
    • (2007) The American Journal of Medicine , vol.120
    • Bergman, R.N.1    Kim, S.P.2    Hsu, I.R.3    Catalano, K.J.4    Chiu, J.D.5
  • 5
    • 0042484813 scopus 로고    scopus 로고
    • The obesity epidemic: Pathophysiology and consequences of obesity
    • Pi-Sunyer FX (2002) The obesity epidemic: pathophysiology and consequences of obesity. Obesity research 10 Suppl 2: 97S-104S.
    • (2002) Obesity Research , vol.10 , Issue.SUPPL. 2
    • Pi-Sunyer, F.X.1
  • 6
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P (1995) Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 7
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
    • Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495.
    • (1996) Cell , vol.84 , pp. 491-495
    • Chen, H.1    Charlat, O.2    Tartaglia, L.A.3    Woolf, E.A.4    Weng, X.5
  • 8
    • 34248393099 scopus 로고    scopus 로고
    • High-fat diets: Modeling the metabolic disorders of human obesity in rodents
    • Buettner R, Scholmerich J, Bollheimer LC (2007) High-fat diets: modeling the metabolic disorders of human obesity in rodents. Obesity 15: 798-808.
    • (2007) Obesity , vol.15 , pp. 798-808
    • Buettner, R.1    Scholmerich, J.2    Bollheimer, L.C.3
  • 11
    • 0037203494 scopus 로고    scopus 로고
    • Consensus view on the role of dietary fat and obesity
    • Foreyt JP, Poston WS (2002) Consensus view on the role of dietary fat and obesity. The American journal of medicine 113 Suppl 9B: 60S-62S.
    • (2002) The American Journal of Medicine , vol.113 , Issue.SUPPL. 9B
    • Foreyt, J.P.1    Poston, W.S.2
  • 12
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 13
    • 84892428390 scopus 로고    scopus 로고
    • Differential effects of high-fat-diet rich in lard oil or soybean oil on osteopontin expression and inflammation of adipose tissue in diet-induced obese rats
    • Wang X, Cheng M, Zhao M, Ge A, Guo F, et al. (2012) Differential effects of high-fat-diet rich in lard oil or soybean oil on osteopontin expression and inflammation of adipose tissue in diet-induced obese rats. European journal of nutrition.
    • (2012) European Journal of Nutrition
    • Wang, X.1    Cheng, M.2    Zhao, M.3    Ge, A.4    Guo, F.5
  • 14
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. The Journal of clinical investigation 112: 1821-1830.
    • (2003) The Journal of Clinical Investigation , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5
  • 15
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, et al. (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nature medicine 11: 183-190.
    • (2005) Nature Medicine , vol.11 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5
  • 16
    • 29044447292 scopus 로고    scopus 로고
    • Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver
    • Boden G, She P, Mozzoli M, Cheung P, Gumireddy K, et al. (2005) Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver. Diabetes 54: 3458-3465.
    • (2005) Diabetes , vol.54 , pp. 3458-3465
    • Boden, G.1    She, P.2    Mozzoli, M.3    Cheung, P.4    Gumireddy, K.5
  • 17
    • 56649094325 scopus 로고    scopus 로고
    • Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
    • Malhi H, Gores GJ (2008) Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Seminars in liver disease 28: 360-369.
    • (2008) Seminars in Liver Disease , vol.28 , pp. 360-369
    • Malhi, H.1    Gores, G.J.2
  • 18
    • 77950543816 scopus 로고    scopus 로고
    • Diacylglycerol-mediated insulin resistance
    • Erion DM, Shulman GI (2010) Diacylglycerol-mediated insulin resistance. Nature medicine 16: 400-402.
    • (2010) Nature Medicine , vol.16 , pp. 400-402
    • Erion, D.M.1    Shulman, G.I.2
  • 20
    • 79960901954 scopus 로고    scopus 로고
    • Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
    • Kiefer FW, Neschen S, Pfau B, Legerer B, Neuhofer A, et al. (2011) Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice. Diabetologia 54: 2132-2142.
    • (2011) Diabetologia , vol.54 , pp. 2132-2142
    • Kiefer, F.W.1    Neschen, S.2    Pfau, B.3    Legerer, B.4    Neuhofer, A.5
  • 22
    • 33646183566 scopus 로고    scopus 로고
    • Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
    • Beutler B, Jiang Z, Georgel P, Crozat K, Croker B, et al. (2006) Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annual review of immunology 24: 353-389.
    • (2006) Annual Review of Immunology , vol.24 , pp. 353-389
    • Beutler, B.1    Jiang, Z.2    Georgel, P.3    Crozat, K.4    Croker, B.5
  • 23
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, et al. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306: 457-461.
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Yilmaz, E.3    Lee, A.H.4    Iwakoshi, N.N.5
  • 24
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil GS (2010) Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140: 900-917.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 25
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schroder M, Kaufman RJ (2005) ER stress and the unfolded protein response. Mutation research 569: 29-63.
    • (2005) Mutation Research , vol.569 , pp. 29-63
    • Schroder, M.1    Kaufman, R.J.2
  • 26
    • 33645156429 scopus 로고    scopus 로고
    • From acute ER stress to physiological roles of the Unfolded Protein Response
    • Wu J, Kaufman RJ (2006) From acute ER stress to physiological roles of the Unfolded Protein Response. Cell death and differentiation 13: 374-384.
    • (2006) Cell Death and Differentiation , vol.13 , pp. 374-384
    • Wu, J.1    Kaufman, R.J.2
  • 27
    • 15944366885 scopus 로고    scopus 로고
    • The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
    • Lee AS (2005) The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods 35: 373-381.
    • (2005) Methods , vol.35 , pp. 373-381
    • Lee, A.S.1
  • 28
    • 49949105827 scopus 로고    scopus 로고
    • The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
    • Li J, Ni M, Lee B, Barron E, Hinton DR, et al. (2008) The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell death and differentiation 15: 1460-1471.
    • (2008) Cell Death and Differentiation , vol.15 , pp. 1460-1471
    • Li, J.1    Ni, M.2    Lee, B.3    Barron, E.4    Hinton, D.R.5
  • 29
    • 34548419344 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte Biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease
    • Gregor MF, Hotamisligil GS (2007) Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. Journal of lipid research 48: 1905-1914.
    • (2007) Journal of Lipid Research , vol.48 , pp. 1905-1914
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 30
    • 82255173966 scopus 로고    scopus 로고
    • The unfolded protein response: From stress pathway to homeostatic regulation
    • Walter P, Ron D (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086.
    • (2011) Science , vol.334 , pp. 1081-1086
    • Walter, P.1    Ron, D.2
  • 32
    • 79952264011 scopus 로고    scopus 로고
    • Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
    • Tabas I, Ron D (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nature cell biology 13: 184-190.
    • (2011) Nature Cell Biology , vol.13 , pp. 184-190
    • Tabas, I.1    Ron, D.2
  • 33
    • 55849096988 scopus 로고    scopus 로고
    • Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
    • Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ (2008) Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. The Journal of clinical investigation 118: 3378-3389.
    • (2008) The Journal of Clinical Investigation , vol.118 , pp. 3378-3389
    • Song, B.1    Scheuner, D.2    Ron, D.3    Pennathur, S.4    Kaufman, R.J.5
  • 34
    • 0034723235 scopus 로고    scopus 로고
    • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
    • Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, et al. (2000) Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287: 664-666.
    • (2000) Science , vol.287 , pp. 664-666
    • Urano, F.1    Wang, X.2    Bertolotti, A.3    Zhang, Y.4    Chung, P.5
  • 36
    • 45849137877 scopus 로고    scopus 로고
    • Regulation of hepatic lipogenesis by the transcription factor XBP1
    • Lee AH, Scapa EF, Cohen DE, Glimcher LH (2008) Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 320: 1492-1496.
    • (2008) Science , vol.320 , pp. 1492-1496
    • Lee, A.H.1    Scapa, E.F.2    Cohen, D.E.3    Glimcher, L.H.4
  • 37
    • 84862776863 scopus 로고    scopus 로고
    • Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets
    • Li J, Huang J, Li JS, Chen H, Huang K, et al. (2012) Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. Journal of hepatology 56: 900-907.
    • (2012) Journal of Hepatology , vol.56 , pp. 900-907
    • Li, J.1    Huang, J.2    Li, J.S.3    Chen, H.4    Huang, K.5
  • 38
    • 52749091008 scopus 로고    scopus 로고
    • Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
    • Boden G, Duan X, Homko C, Molina EJ, Song W, et al. (2008) Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals. Diabetes 57: 2438-2444.
    • (2008) Diabetes , vol.57 , pp. 2438-2444
    • Boden, G.1    Duan, X.2    Homko, C.3    Molina, E.J.4    Song, W.5
  • 40
    • 78349307962 scopus 로고    scopus 로고
    • Differential effects of high MUFA with high or low P/S ratio (polyunsaturated to saturated fatty acids) on improving hepatic lipolytic enzymes and mediating PPARc related with lipoprotein lipase and hormone-sensitive lipase of white adipose tissue in dietinduced obese hamster
    • Liao FH, Liou TH, Chiu WC, Shieh MJ, Chien YW (2010) Differential effects of high MUFA with high or low P/S ratio (polyunsaturated to saturated fatty acids) on improving hepatic lipolytic enzymes and mediating PPARc related with lipoprotein lipase and hormone-sensitive lipase of white adipose tissue in dietinduced obese hamster. International Journal of Obesity 34: 1608-1617.
    • (2010) International Journal of Obesity , vol.34 , pp. 1608-1617
    • Liao, F.H.1    Liou, T.H.2    Chiu, W.C.3    Shieh, M.J.4    Chien, Y.W.5
  • 42
    • 84856111924 scopus 로고    scopus 로고
    • The unfolded protein response: Controlling cell fate decisions under ER stress and beyond
    • Hetz C (2012) The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nature reviews Molecular cell biology 13: 89-102.
    • (2012) Nature Reviews Molecular Cell Biology , vol.13 , pp. 89-102
    • Hetz, C.1
  • 43
    • 0037083755 scopus 로고    scopus 로고
    • IRE1- mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, et al. (2002) IRE1- mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes & development 16: 452-466.
    • (2002) Genes & Development , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5
  • 44
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • Oyadomari S, Mori M (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell death and differentiation 11: 381-389.
    • (2004) Cell Death and Differentiation , vol.11 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 45
    • 77954626079 scopus 로고    scopus 로고
    • High-fat diet stimulates IL-1 type I receptor-mediated inflammatory signaling in the skeletal muscle of mice
    • Kim SJ, Choi Y, Jun HS, Kim BM, Na HK, et al. (2010) High-fat diet stimulates IL-1 type I receptor-mediated inflammatory signaling in the skeletal muscle of mice. Molecular nutrition & food research 54: 1014-1020.
    • (2010) Molecular Nutrition & Food Research , vol.54 , pp. 1014-1020
    • Kim, S.J.1    Choi, Y.2    Jun, H.S.3    Kim, B.M.4    Na, H.K.5
  • 46
    • 0029065480 scopus 로고
    • Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice
    • Surwit RS, Feinglos MN, Rodin J, Sutherland A, Petro AE, et al. (1995) Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 44: 645-651.
    • (1995) Metabolism , vol.44 , pp. 645-651
    • Surwit, R.S.1    Feinglos, M.N.2    Rodin, J.3    Sutherland, A.4    Petro, A.E.5
  • 47
    • 43849104298 scopus 로고    scopus 로고
    • Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: Evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance
    • Vinayagamoorthi R, Bobby Z, Sridhar MG (2008) Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. The Journal of endocrinology 197: 287-296.
    • (2008) The Journal of Endocrinology , vol.197 , pp. 287-296
    • Vinayagamoorthi, R.1    Bobby, Z.2    Sridhar, M.G.3
  • 50
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 51
    • 34547460043 scopus 로고    scopus 로고
    • Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease
    • Qureshi K, Abrams GA (2007) Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease. World journal of gastroenterology: WJG 13: 3540-3553.
    • (2007) World Journal of Gastroenterology: WJG , vol.13 , pp. 3540-3553
    • Qureshi, K.1    Abrams, G.A.2
  • 52
    • 58649096801 scopus 로고    scopus 로고
    • Saturated fatty acid-mediated inflammation and insulin resistance in adipose tissue: Mechanisms of action and implications
    • Kennedy A, Martinez K, Chuang CC, LaPoint K, McIntosh M (2009) Saturated fatty acid-mediated inflammation and insulin resistance in adipose tissue: mechanisms of action and implications. The Journal of nutrition 139: 1-4.
    • (2009) The Journal of Nutrition , vol.139 , pp. 1-4
    • Kennedy, A.1    Martinez, K.2    Chuang, C.C.3    LaPoint, K.4    McIntosh, M.5
  • 53
    • 72749100942 scopus 로고    scopus 로고
    • A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome
    • van Dijk SJ, Feskens EJ, Bos MB, Hoelen DW, Heijligenberg R, et al. (2009) A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. The American journal of clinical nutrition 90: 1656-1664.
    • (2009) The American Journal of Clinical Nutrition , vol.90 , pp. 1656-1664
    • Van Dijk, S.J.1    Feskens, E.J.2    Bos, M.B.3    Hoelen, D.W.4    Heijligenberg, R.5
  • 54
    • 33846323706 scopus 로고    scopus 로고
    • Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acidinduced inflammatory changes in the interaction between adipocytes and macrophages
    • Suganami T, Tanimoto-Koyama K, Nishida J, Itoh M, Yuan X, et al. (2007) Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acidinduced inflammatory changes in the interaction between adipocytes and macrophages. Arteriosclerosis, thrombosis, and vascular biology 27: 84-91.
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 84-91
    • Suganami, T.1    Tanimoto-Koyama, K.2    Nishida, J.3    Itoh, M.4    Yuan, X.5
  • 55
    • 77955492173 scopus 로고    scopus 로고
    • Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
    • Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, et al. (2010) Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia 53: 1795-1806.
    • (2010) Diabetologia , vol.53 , pp. 1795-1806
    • Ehses, J.A.1    Meier, D.T.2    Wueest, S.3    Rytka, J.4    Boller, S.5
  • 56
    • 77954220714 scopus 로고    scopus 로고
    • Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists
    • Zhao W, Wang L, Zhang L, Yuan C, Kuo PC, et al. (2010) Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists. The Journal of biological chemistry 285: 20452-20461.
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 20452-20461
    • Zhao, W.1    Wang, L.2    Zhang, L.3    Yuan, C.4    Kuo, P.C.5
  • 57
  • 58
    • 77951181647 scopus 로고    scopus 로고
    • Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance
    • Kiefer FW, Zeyda M, Gollinger K, Pfau B, Neuhofer A, et al. (2010) Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes 59: 935-946.
    • (2010) Diabetes , vol.59 , pp. 935-946
    • Kiefer, F.W.1    Zeyda, M.2    Gollinger, K.3    Pfau, B.4    Neuhofer, A.5
  • 59
    • 34948813665 scopus 로고    scopus 로고
    • Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
    • Nomiyama T, Perez-Tilve D, Ogawa D, Gizard F, Zhao Y, et al. (2007) Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice. The Journal of clinical investigation 117: 2877-2888.
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 2877-2888
    • Nomiyama, T.1    Perez-Tilve, D.2    Ogawa, D.3    Gizard, F.4    Zhao, Y.5
  • 60
    • 77951290227 scopus 로고    scopus 로고
    • TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
    • Martinon F, Chen X, Lee AH, Glimcher LH (2010) TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nature immunology 11: 411-418.
    • (2010) Nature Immunology , vol.11 , pp. 411-418
    • Martinon, F.1    Chen, X.2    Lee, A.H.3    Glimcher, L.H.4
  • 61
    • 30944451788 scopus 로고    scopus 로고
    • Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
    • Wang D, Wei Y, Pagliassotti MJ (2006) Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology 147: 943-951.
    • (2006) Endocrinology , vol.147 , pp. 943-951
    • Wang, D.1    Wei, Y.2    Pagliassotti, M.J.3
  • 65
  • 66
    • 36049049392 scopus 로고    scopus 로고
    • IRE1 signaling affects cell fate during the unfolded protein response
    • Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, et al. (2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949.
    • (2007) Science , vol.318 , pp. 944-949
    • Lin, J.H.1    Li, H.2    Yasumura, D.3    Cohen, H.R.4    Zhang, C.5
  • 67
    • 79953794116 scopus 로고    scopus 로고
    • The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis
    • Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, et al. (2011) The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis. The EMBO journal 30: 1357-1375.
    • (2011) The EMBO Journal , vol.30 , pp. 1357-1375
    • Zhang, K.1    Wang, S.2    Malhotra, J.3    Hassler, J.R.4    Back, S.H.5
  • 68
    • 77951645463 scopus 로고    scopus 로고
    • A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells
    • Qiu Y, Mao T, Zhang Y, Shao M, You J, et al. (2010) A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Science signaling 3: ra7.
    • (2010) Science Signaling , vol.3
    • Qiu, Y.1    Mao, T.2    Zhang, Y.3    Shao, M.4    You, J.5
  • 70
    • 9144228073 scopus 로고    scopus 로고
    • Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II
    • Yamamoto K, Yoshida H, Kokame K, Kaufman RJ, Mori K (2004) Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. Journal of biochemistry 136: 343-350.
    • (2004) Journal of Biochemistry , vol.136 , pp. 343-350
    • Yamamoto, K.1    Yoshida, H.2    Kokame, K.3    Kaufman, R.J.4    Mori, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.