메뉴 건너뛰기




Volumn 59, Issue 4, 2010, Pages 935-946

Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; NEUTRALIZING ANTIBODY; OSTEOPONTIN; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

EID: 77951181647     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0404     Document Type: Article
Times cited : (163)

References (55)
  • 1
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature 2006;444:881-887
    • (2006) Nature , vol.444 , pp. 881-887
    • Despres, J.P.1    Lemieux, I.2
  • 3
    • 34247857663 scopus 로고    scopus 로고
    • Obesity, inflammation, and insulin resistance
    • Shoelson SE, Herrero L, Naaz A. Obesity, inflammation, and insulin resistance. Gastroenterology 2007;132:2169-2180
    • (2007) Gastroenterology , vol.132 , pp. 2169-2180
    • Shoelson, S.E.1    Herrero, L.2    Naaz, A.3
  • 4
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444: 860-867
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 7
    • 33846201363 scopus 로고    scopus 로고
    • Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
    • Fain JN. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 2006;74:443-477
    • (2006) Vitam Horm , vol.74 , pp. 443-477
    • Fain, J.N.1
  • 8
    • 33644826101 scopus 로고    scopus 로고
    • Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin
    • Curat CA, Wegner V, Sengenes C, Miranville A, Tonus C, Busse R, Bouloumie A. Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 2006;49:744-747
    • (2006) Diabetologia , vol.49 , pp. 744-747
    • Curat, C.A.1    Wegner, V.2    Sengenes, C.3    Miranville, A.4    Tonus, C.5    Busse, R.6    Bouloumie, A.7
  • 9
    • 34548354722 scopus 로고    scopus 로고
    • Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
    • Lond
    • Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Gyori G, Zlabinger GJ, Stulnig TM. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) 2007;31:1420-1428
    • (2007) Int J Obes , vol.31 , pp. 1420-1428
    • Zeyda, M.1    Farmer, D.2    Todoric, J.3    Aszmann, O.4    Speiser, M.5    Gyori, G.6    Zlabinger, G.J.7    Stulnig, T.M.8
  • 11
    • 7044264360 scopus 로고    scopus 로고
    • Role of osteopontin in adhesion, migration, cell survival and bone remodeling
    • Standal T, Borset M, Sundan A. Role of osteopontin in adhesion, migration, cell survival and bone remodeling. Exp Oncol 2004;26:179-184
    • (2004) Exp Oncol , vol.26 , pp. 179-184
    • Standal, T.1    Borset, M.2    Sundan, A.3
  • 12
    • 32644467590 scopus 로고    scopus 로고
    • Osteopontin: Role in cell signaling and cancer progression
    • Rangaswami H, Bulbule A, Kundu GC. Osteopontin: role in cell signaling and cancer progression. Trends Cell Biol 2006;16:79-87
    • (2006) Trends Cell Biol , vol.16 , pp. 79-87
    • Rangaswami, H.1    Bulbule, A.2    Kundu, G.C.3
  • 14
    • 0032479268 scopus 로고    scopus 로고
    • Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent
    • Teti A, Farina AR, Villanova I, Tiberio A, Tacconelli A, Sciortino G, Chambers AF, Gulino A, Mackay AR. Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent. Int J Cancer 1998;77:82-93
    • (1998) Int J Cancer , vol.77 , pp. 82-93
    • Teti, A.1    Farina, A.R.2    Villanova, I.3    Tiberio, A.4    Tacconelli, A.5    Sciortino, G.6    Chambers, A.F.7    Gulino, A.8    Mackay, A.R.9
  • 15
    • 20144367221 scopus 로고    scopus 로고
    • Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism
    • Xu G, Sun W, He D, Wang L, Zheng W, Nie H, Ni L, Zhang D, Li N, Zhang J. Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism. J Rheumatol 2005;32:410-416
    • (2005) J Rheumatol , vol.32 , pp. 410-416
    • Xu, G.1    Sun, W.2    He, D.3    Wang, L.4    Zheng, W.5    Nie, H.6    Ni, L.7    Zhang, D.8    Li, N.9    Zhang, J.10
  • 16
    • 0037432181 scopus 로고    scopus 로고
    • Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions
    • Isoda K, Kamezawa Y, Ayaori M, Kusuhara M, Tada N, Ohsuzu F. Osteopontin transgenic mice fed a high-cholesterol diet develop early fatty-streak lesions. Circulation 2003;107:679-681
    • (2003) Circulation , vol.107 , pp. 679-681
    • Isoda, K.1    Kamezawa, Y.2    Ayaori, M.3    Kusuhara, M.4    Tada, N.5    Ohsuzu, F.6
  • 18
    • 42149085600 scopus 로고    scopus 로고
    • Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer
    • Ramaiah SK, Rittling S. Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer. Toxicol Sci 2008;103:4-13
    • (2008) Toxicol Sci , vol.103 , pp. 4-13
    • Ramaiah, S.K.1    Rittling, S.2
  • 20
    • 0033770543 scopus 로고    scopus 로고
    • Increased expression of osteopontin in activated Kupffer cells and hepatic macrophages during macrophage migration in Propionibacterium acnes-treated rat liver
    • Wang Y, Mochida S, Kawashima R, Inao M, Matsui A, YouLuTu ZY, Nagoshi S, Uede T, Fujiwara K. Increased expression of osteopontin in activated Kupffer cells and hepatic macrophages during macrophage migration in Propionibacterium acnes-treated rat liver. J Gastroenterol 2000;35:696-701
    • (2000) J Gastroenterol , vol.35 , pp. 696-701
    • Wang, Y.1    Mochida, S.2    Kawashima, R.3    Inao, M.4    Matsui, A.5    Youlutu, Z.Y.6    Nagoshi, S.7    Uede, T.8    Fujiwara, K.9
  • 21
  • 22
    • 3042550624 scopus 로고    scopus 로고
    • Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model
    • Sahai A, Malladi P, Melin-Aldana H, Green RM, Whitington PF. Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. Am J Physiol Gastrointest Liver Physiol 2004;287:G264-G273
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Sahai, A.1    Malladi, P.2    Melin-Aldana, H.3    Green, R.M.4    Whitington, P.F.5
  • 23
    • 7044241291 scopus 로고    scopus 로고
    • Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: Role of short-form leptin receptors and osteopontin
    • Sahai A, Malladi P, Pan X, Paul R, Melin-Aldana H, Green RM, Whitington PF. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol 2004;287:G1035-G1043
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Sahai, A.1    Malladi, P.2    Pan, X.3    Paul, R.4    Melin-Aldana, H.5    Green, R.M.6    Whitington, P.F.7
  • 28
    • 0031846461 scopus 로고    scopus 로고
    • How to measure insulin sensitivity
    • Ferrannini E, Mari A. How to measure insulin sensitivity. J Hypertens 1998;16:895-906
    • (1998) J Hypertens , vol.16 , pp. 895-906
    • Ferrannini, E.1    Mari, A.2
  • 29
    • 33746772121 scopus 로고    scopus 로고
    • Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
    • Todoric J, Loffler M, Huber J, Bilban M, Reimers M, Kadl A, Zeyda M, Waldhausl W, Stulnig TM. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 2006;49:2109-2119
    • (2006) Diabetologia , vol.49 , pp. 2109-2119
    • Todoric, J.1    Loffler, M.2    Huber, J.3    Bilban, M.4    Reimers, M.5    Kadl, A.6    Zeyda, M.7    Waldhausl, W.8    Stulnig, T.M.9
  • 30
    • 0037066776 scopus 로고    scopus 로고
    • Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle
    • Haemmerle G, Zimmermann R, Strauss JG, Kratky D, Riederer M, Knipping G, Zechner R. Hormone-sensitive lipase deficiency in mice changes the plasma lipid profile by affecting the tissue-specific expression pattern of lipoprotein lipase in adipose tissue and muscle. J Biol Chem 2002;277:12946-12952
    • (2002) J Biol Chem , vol.277 , pp. 12946-12952
    • Haemmerle, G.1    Zimmermann, R.2    Strauss, J.G.3    Kratky, D.4    Riederer, M.5    Knipping, G.6    Zechner, R.7
  • 31
    • 34249684280 scopus 로고    scopus 로고
    • Osteopontin prevents monocyte recirculation and apoptosis
    • Burdo TH, Wood MR, Fox HS. Osteopontin prevents monocyte recirculation and apoptosis. J Leukoc Biol 2007;81:1504-1511
    • (2007) J Leukoc Biol , vol.81 , pp. 1504-1511
    • Burdo, T.H.1    Wood, M.R.2    Fox, H.S.3
  • 36
    • 0034284540 scopus 로고    scopus 로고
    • IL-10 attenuates IFN-alpha-activated STAT1 in the liver: Involvement of SOCS2 and SOCS3
    • Shen X, Hong F, Nguyen VA, Gao B. IL-10 attenuates IFN-alpha-activated STAT1 in the liver: involvement of SOCS2 and SOCS3. FEBS Lett 2000; 480:132-136
    • (2000) FEBS Lett , vol.480 , pp. 132-136
    • Shen, X.1    Hong, F.2    Nguyen, V.A.3    Gao, B.4
  • 37
    • 0035038729 scopus 로고    scopus 로고
    • Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression
    • Lochhead PA, Coghlan M, Rice SQ, Sutherland C. Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression. Diabetes 2001;50:937-946
    • (2001) Diabetes , vol.50 , pp. 937-946
    • Lochhead, P.A.1    Coghlan, M.2    Rice, S.Q.3    Sutherland, C.4
  • 38
    • 0037189517 scopus 로고    scopus 로고
    • Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice
    • Sun Y, Liu S, Ferguson S, Wang L, Klepcyk P, Yun JS, Friedman JE. Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice. J Biol Chem 2002;277:23301-23307
    • (2002) J Biol Chem , vol.277 , pp. 23301-23307
    • Sun, Y.1    Liu, S.2    Ferguson, S.3    Wang, L.4    Klepcyk, P.5    Yun, J.S.6    Friedman, J.E.7
  • 39
    • 0021676059 scopus 로고
    • Endocrinological aspects of obesity
    • Jung R. Endocrinological aspects of obesity. Clin Endocrinol Metab 1984;13:597-612
    • (1984) Clin Endocrinol Metab , vol.13 , pp. 597-612
    • Jung, R.1
  • 41
    • 47249145601 scopus 로고    scopus 로고
    • Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells
    • Fan K, Dai J, Wang H, Wei H, Cao Z, Hou S, Qian W, Wang H, Li B, Zhao J, Xu H, Yang C, Guo Y. Treatment of collagen-induced arthritis with an anti-osteopontin monoclonal antibody through promotion of apoptosis of both murine and human activated T cells. Arthritis Rheum 2008;58:2041-2052
    • (2008) Arthritis Rheum , vol.58 , pp. 2041-2052
    • Fan, K.1    Dai, J.2    Wang, H.3    Wei, H.4    Cao, Z.5    Hou, S.6    Qian, W.7    Wang, H.8    Li, B.9    Zhao, J.10    Xu, H.11    Yang, C.12    Guo, Y.13
  • 42
    • 1642316557 scopus 로고    scopus 로고
    • Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: Evidence of a role for an intracellular form of osteopontin
    • Zhu B, Suzuki K, Goldberg HA, Rittling SR, Denhardt DT, McCulloch CA, Sodek J. Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: evidence of a role for an intracellular form of osteopontin. J Cell Physiol 2004;198:155-167
    • (2004) J Cell Physiol , vol.198 , pp. 155-167
    • Zhu, B.1    Suzuki, K.2    Goldberg, H.A.3    Rittling, S.R.4    Denhardt, D.T.5    McCulloch, C.A.6    Sodek, J.7
  • 43
    • 33644669749 scopus 로고    scopus 로고
    • Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease
    • Banerjee A, Apte UM, Smith R, Ramaiah SK. Higher neutrophil infiltration mediated by osteopontin is a likely contributing factor to the increased susceptibility of females to alcoholic liver disease. J Pathol 2006;208:473-485
    • (2006) J Pathol , vol.208 , pp. 473-485
    • Banerjee, A.1    Apte, U.M.2    Smith, R.3    Ramaiah, S.K.4
  • 45
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 2000; 275:9047-9054
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 46
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001;280:E745-E751
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3    Wood, L.4    Ranganathan, G.5
  • 48
    • 36249009634 scopus 로고    scopus 로고
    • Pathology of nonalcoholic fatty liver disease
    • Yeh MM, Brunt EM. Pathology of nonalcoholic fatty liver disease. Am J Clin Pathol 2007;128:837-847
    • (2007) Am J Clin Pathol , vol.128 , pp. 837-847
    • Yeh, M.M.1    Brunt, E.M.2
  • 49
    • 0032771475 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Diehl AM. Nonalcoholic steatohepatitis. Semin Liver Dis 1999;19:221-229
    • (1999) Semin Liver Dis , vol.19 , pp. 221-229
    • Diehl, A.M.1
  • 53
    • 48449095742 scopus 로고    scopus 로고
    • STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 β
    • Moh A, Zhang W, Yu S, Wang J, Xu X, Li J, Fu XY. STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 β. Diabetes 2008;57:1227-1235
    • (2008) Diabetes , vol.57 , pp. 1227-1235
    • Moh, A.1    Zhang, W.2    Yu, S.3    Wang, J.4    Xu, X.5    Li, J.6    Fu, X.Y.7
  • 55
    • 29444446954 scopus 로고    scopus 로고
    • Protective molecules: C-reactive protein (CRP), SAP, pentraxin3 (PTX3), mannose-binding lectin (MBL), and apolipoprotein A1 (Apo A1), and their autoantibodies: prevalence and clinical significance in autoimmunity
    • Kravitz MS, Pitashny M, Shoenfeld Y. Protective molecules: C-reactive protein (CRP), SAP, pentraxin3 (PTX3), mannose-binding lectin (MBL), and apolipoprotein A1 (Apo A1), and their autoantibodies: prevalence and clinical significance in autoimmunity. J Clin Immunol 2005;25:582-591
    • (2005) J Clin Immunol , vol.25 , pp. 582-591
    • Kravitz, M.S.1    Pitashny, M.2    Shoenfeld, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.