-
1
-
-
40349083852
-
Evidence of different metabolic phenotypes in humans
-
DOI 10.1073/pnas.0705685105
-
Assfalg M, Bertini I, Colangiuli D, Luchinat C, Schäfer H, Schütz B, et al. Evidence of different metabolic phenotypes in humans. Proc Natl Acad Sci USA 2008;105:1420-4. (Pubitemid 351346527)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1420-1424
-
-
Assfalg, M.1
Bertini, I.2
Colangiuli, D.3
Luchinat, C.4
Schafer, H.5
Schutz, B.6
Spraul, M.7
-
2
-
-
70349898794
-
Individual human phenotypes in metabolic space and time
-
Bernini P, Bertini I, Luchinat C, Nepi S, Saccenti E, Schäfer H, et al. Individual human phenotypes in metabolic space and time. J Proteome Res 2009;8:4264-71.
-
(2009)
J Proteome Res
, vol.8
, pp. 4264-4271
-
-
Bernini, P.1
Bertini, I.2
Luchinat, C.3
Nepi, S.4
Saccenti, E.5
Schäfer, H.6
-
3
-
-
0036007687
-
Metabolomics: The link between genotypes and phenotypes
-
Fiehn O. Metabolomics: The link between genotypes and phenotypes. Plant Mol Biol 2002;48:155-71.
-
(2002)
Plant Mol Biol
, vol.48
, pp. 155-171
-
-
Fiehn, O.1
-
4
-
-
84858055067
-
Recent advances in metabolomics in oncology
-
O'Connell TM. Recent advances in metabolomics in oncology. Bioanalysis 2012;4:431-51.
-
(2012)
Bioanalysis
, vol.4
, pp. 431-451
-
-
O'Connell, T.M.1
-
5
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011;144:646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956;123:309-14.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
9
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
DOI 10.1158/0008-5472.CAN-03-2904
-
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 2004;64:3892-9. (Pubitemid 38697301)
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
Thompson, C.B.11
-
10
-
-
76049100577
-
HIF-1: Upstream and downstream of cancer metabolism
-
Semenza GL. HIF-1: Upstream and downstream of cancer metabolism. Curr Opin Genet Dev 2010;20:51-6.
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 51-56
-
-
Semenza, G.L.1
-
11
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006;3:187-97.
-
(2006)
Cell Metab
, vol.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
Lim, A.L.4
Denko, N.C.5
-
12
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006;3:177-85.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
13
-
-
57649130593
-
Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance
-
Lu CW, Lin SC, Chen KF, Lai YY, Tsai SJ. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance. J Biol Chem 2008;283:28106-14.
-
(2008)
J Biol Chem
, vol.283
, pp. 28106-28114
-
-
Lu, C.W.1
Lin, S.C.2
Chen, K.F.3
Lai, Y.Y.4
Tsai, S.J.5
-
14
-
-
0030882879
-
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53
-
DOI 10.1074/jbc.272.36.22776
-
Mathupala SP, Heese C, Pedersen PL. Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53. J Biol Chem 1997;272:22776-80. (Pubitemid 27386097)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.36
, pp. 22776-22780
-
-
Mathupala, S.P.1
Heese, C.2
Pedersen, P.L.3
-
15
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
DOI 10.1126/science.1126863
-
Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, et al. p53 regulates mitochondrial respiration. Science 2006;312:1650-3. (Pubitemid 43902663)
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.-G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
16
-
-
33745918951
-
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
-
DOI 10.1016/j.cell.2006.05.036, PII S0092867406007628
-
Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 2006;126:107-20. (Pubitemid 44040989)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.C.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
17
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, et al. Glycolytic enzymes can modulate cellular life span. Cancer Res 2005;65:177-85. (Pubitemid 40070808)
-
(2005)
Cancer Research
, vol.65
, Issue.1
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
18
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
-
DOI 10.1016/j.ccr.2004.11.022, PII S153561080400368X
-
Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 2005;7:77-85. (Pubitemid 40126384)
-
(2005)
Cancer Cell
, vol.7
, Issue.1
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
19
-
-
23644448721
-
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
-
DOI 10.1016/j.ccr.2005.06.017, PII S1535610805002266
-
Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, Chung YL, et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability. Cancer Cell 2005;8:143-53. (Pubitemid 41132743)
-
(2005)
Cancer Cell
, vol.8
, Issue.2
, pp. 143-153
-
-
Isaacs, J.S.1
Yun, J.J.2
Mole, D.R.3
Lee, S.4
Torres-Cabala, C.5
Chung, Y.-L.6
Merino, M.7
Trepel, J.8
Zbar, B.9
Toro, J.10
Ratcliffe, P.J.11
Linehan, W.M.12
Neckers, L.13
-
20
-
-
33746930794
-
Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer
-
DOI 10.1038/sj.onc.1209594, PII 1209594
-
King A, Selak MA, Gottlieb E. Succinate dehydrogenase and fumarate hydratase: Linking mitochondrial dysfunction and cancer. Oncogene 2006;25:4675-82. (Pubitemid 44187617)
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4675-4682
-
-
King, A.1
Selak, M.A.2
Gottlieb, E.3
-
21
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
-
DOI 10.1093/hmg/ddi227
-
Pollard PJ, Brière JJ, Alam NA, Barwell J, Barclay E, Wortham NC, et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet 2005;14:2231-9. (Pubitemid 41418022)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.15
, pp. 2231-2239
-
-
Pollard, P.J.1
Briere, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
Hunt, T.7
Mitchell, M.8
Olpin, S.9
Moat, S.J.10
Hargreaves, I.P.11
Heales, S.J.12
Chung, Y.L.13
Griffiths, J.R.14
Dalgleish, A.15
McGrath, J.A.16
Gleeson, M.J.17
Hodgson, S.V.18
Poulsom, R.19
Rustin, P.20
Tomlinson, I.P.M.21
more..
-
22
-
-
34247553146
-
Cell-permeating α-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells
-
DOI 10.1128/MCB.01927-06
-
MacKenzie ED, Selak MA, Tennant DA, Payne LJ, Crosby S, Frederiksen CM, et al. Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells. Mol Cell Biol 2007;27:3282-9. (Pubitemid 46685207)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.9
, pp. 3282-3289
-
-
MacKenzie, E.D.1
Selak, M.A.2
Tennant, D.A.3
Payne, L.J.4
Crosby, S.5
Frederiksen, C.M.6
Watson, D.G.7
Gottlieb, E.8
-
23
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, et al. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci USA 2007;104:19345-50.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
-
25
-
-
76249110471
-
Rethinking the Warburg effect with Myc micromanaging glutamine metabolism
-
Dang CV. Rethinking the Warburg effect with Myc micromanaging glutamine metabolism. Cancer Res 2010;70:859-62.
-
(2010)
Cancer Res
, vol.70
, pp. 859-862
-
-
Dang, C.V.1
-
26
-
-
64749116346
-
C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, et al. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 2009;458:762-5.
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.C.3
Lee, Y.S.4
Kita, K.5
Ochi, T.6
-
27
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
DOI 10.1038/nature06734, PII NATURE06734
-
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R, et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 2008;452:230-3. (Pubitemid 351380249)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
28
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science 2009;324:1029-33.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
29
-
-
79952280229
-
P53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
-
Jiang P, Du W, Wang X, Mancuso A, Gao X, Wu M, et al. p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nat Cell Biol 2011;13:310-6.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 310-316
-
-
Jiang, P.1
Du, W.2
Wang, X.3
Mancuso, A.4
Gao, X.5
Wu, M.6
-
30
-
-
77956674635
-
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
-
Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, et al. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science 2010;329:1492-9.
-
(2010)
Science
, vol.329
, pp. 1492-1499
-
-
Vander Heiden, M.G.1
Locasale, J.W.2
Swanson, K.D.3
Sharfi, H.4
Heffron, G.J.5
Amador-Noguez, D.6
-
31
-
-
18844406001
-
Measuring the metabolome: Current analytical technologies
-
DOI 10.1039/b418288j
-
Dunn WB, Bailey NJ, Johnson HE. Measuring the metabolome: Current analytical technologies. Analyst 2005;130:606-25. (Pubitemid 40685888)
-
(2005)
Analyst
, vol.130
, Issue.5
, pp. 606-625
-
-
Dunn, W.B.1
Bailey, N.J.C.2
Johnson, H.E.3
-
32
-
-
83455203337
-
Modern analytical techniques in metabolomics analysis
-
Zhang A, Sun H, Wang P, Han Y, Wang X. Modern analytical techniques in metabolomics analysis. Analyst 2012;137:293-300.
-
(2012)
Analyst
, vol.137
, pp. 293-300
-
-
Zhang, A.1
Sun, H.2
Wang, P.3
Han, Y.4
Wang, X.5
-
33
-
-
78650315006
-
Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy
-
Dunn WB, Broadhurst DI, Atherton HJ, Goodacre R, Griffin JL. Systems level studies of mammalian metabolomes: The roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Soc Rev 2011;40:387-426.
-
(2011)
Chem Soc Rev
, vol.40
, pp. 387-426
-
-
Dunn, W.B.1
Broadhurst, D.I.2
Atherton, H.J.3
Goodacre, R.4
Griffin, J.L.5
-
34
-
-
84855732698
-
Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids
-
Duarte IF, Gil AM. Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids. Prog Nucl Magn Reson Spectrosc 2012;62:51-74.
-
(2012)
Prog Nucl Magn Reson Spectrosc
, vol.62
, pp. 51-74
-
-
Duarte, I.F.1
Gil, A.M.2
-
35
-
-
77956597651
-
High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues
-
Beckonert O, Coen M, Keun HC, Wang Y, Ebbels TM, Holmes E, et al. High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues. Nat Protoc 2010;5:1019-32.
-
(2010)
Nat Protoc
, vol.5
, pp. 1019-1032
-
-
Beckonert, O.1
Coen, M.2
Keun, H.C.3
Wang, Y.4
Ebbels, T.M.5
Holmes, E.6
-
36
-
-
84862016091
-
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo
-
Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, et al. Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo. Cell Metab 2012;15:827-37.
-
(2012)
Cell Metab
, vol.15
, pp. 827-837
-
-
Marin-Valencia, I.1
Yang, C.2
Mashimo, T.3
Cho, S.4
Baek, H.5
Yang, X.L.6
-
37
-
-
79951507755
-
Analysis of cancer metabolism by imaging hyperpolarized nuclei: Prospects for translation to clinical research
-
Kurhanewicz J, Vigneron DB, Brindle K, Chekmenev EY, Comment A, Cunningham CH, et al. Analysis of cancer metabolism by imaging hyperpolarized nuclei: Prospects for translation to clinical research. Neoplasia 2011;13:81-97.
-
(2011)
Neoplasia
, vol.13
, pp. 81-97
-
-
Kurhanewicz, J.1
Vigneron, D.B.2
Brindle, K.3
Chekmenev, E.Y.4
Comment, A.5
Cunningham, C.H.6
-
38
-
-
77958062885
-
Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer
-
Lin L, Yu Q, Yan X, Hang W, Zheng J, Xing J, et al. Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer. Analyst 2010;135:2970-8.
-
(2010)
Analyst
, vol.135
, pp. 2970-2978
-
-
Lin, L.1
Yu, Q.2
Yan, X.3
Hang, W.4
Zheng, J.5
Xing, J.6
-
39
-
-
77956508105
-
Rapid mass spectrometric metabolic profiling of blood sera detects ovarian cancer with high accuracy
-
Zhou M, Guan W, Walker LD, Mezencev R, Benigno BB, Gray A, et al. Rapid mass spectrometric metabolic profiling of blood sera detects ovarian cancer with high accuracy. Cancer Epidemiol Biomarkers Prev 2010;19:2262-71.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 2262-2271
-
-
Zhou, M.1
Guan, W.2
Walker, L.D.3
Mezencev, R.4
Benigno, B.B.5
Gray, A.6
-
40
-
-
80051666139
-
Bioinformatics tools for cancer metabolomics
-
Blekherman G, Laubenbacher R, Cortes DF, Mendes P, Torti FM, Akman S, et al. Bioinformatics tools for cancer metabolomics. Metabolomics 2011;7:329-43.
-
(2011)
Metabolomics
, vol.7
, pp. 329-343
-
-
Blekherman, G.1
Laubenbacher, R.2
Cortes, D.F.3
Mendes, P.4
Torti, F.M.5
Akman, S.6
-
41
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 2009;360:765-73.
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
-
42
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009;462:739-44.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
43
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
-
Ward PS, Thompson CB. Metabolic reprogramming: A cancer hallmark even warburg did not anticipate. Cancer Cell 2012;21:297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
44
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
Reitman ZJ, Jin G, Karoly ED, Spasojevic I, Yang J, Kinzler KW, et al. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA 2011;108:3270-5.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3270-3275
-
-
Reitman, Z.J.1
Jin, G.2
Karoly, E.D.3
Spasojevic, I.4
Yang, J.5
Kinzler, K.W.6
-
45
-
-
77955517340
-
Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours
-
Jentzmik F, Stephan C, Miller K, Schrader M, Erbersdobler A, Kristiansen G, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
-
(2010)
Eur Urol
, vol.58
, pp. 12-18
-
-
Jentzmik, F.1
Stephan, C.2
Miller, K.3
Schrader, M.4
Erbersdobler, A.5
Kristiansen, G.6
-
46
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 2009;457:910-4.
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
Khan, A.P.4
Cao, Q.5
Yu, J.6
-
47
-
-
84861420588
-
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
-
Jain M, Nilsson R, Sharma S, Madhusudhan N, Kitami T, Souza AL, et al. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 2012;336:1040-4.
-
(2012)
Science
, vol.336
, pp. 1040-1044
-
-
Jain, M.1
Nilsson, R.2
Sharma, S.3
Madhusudhan, N.4
Kitami, T.5
Souza, A.L.6
-
48
-
-
8844261879
-
Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases
-
DOI 10.1016/j.jchromb.2004.09.032, PII S1570023204007433
-
Yang J, Xu G, Zheng Y, Kong H, Pang T, Lv S, et al. Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases. J Chromatogr B Analyt Technol Biomed Life Sci 2004;813:59-65. (Pubitemid 39535429)
-
(2004)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.813
, Issue.1-2
, pp. 59-65
-
-
Yang, J.1
Xu, G.2
Zheng, Y.3
Kong, H.4
Pang, T.5
Lv, S.6
Yang, Q.7
-
49
-
-
84873269399
-
Urinary metabolic profiling identifies a key role for glycocholic acid in human liver cancer by ultra-performance liquid-chromatography coupled with high-definition mass spectrometry
-
Wang X, Zhang A, Sun H, Yan G, Han Y, Ye Y. Urinary metabolic profiling identifies a key role for glycocholic acid in human liver cancer by ultra-performance liquid-chromatography coupled with high-definition mass spectrometry. Clin Chim Acta 2013;418:86-90.
-
(2013)
Clin Chim Acta
, vol.418
, pp. 86-90
-
-
Wang, X.1
Zhang, A.2
Sun, H.3
Yan, G.4
Han, Y.5
Ye, Y.6
-
50
-
-
84855206110
-
Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma
-
M110.004945
-
Chen T, Xie G, Wang X, Fan J, Qiu Y, Zheng X, et al. Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma. Mol Cell Proteomics 2011;10:M110.004945.
-
(2011)
Mol Cell Proteomics
, pp. 10
-
-
Chen, T.1
Xie, G.2
Wang, X.3
Fan, J.4
Qiu, Y.5
Zheng, X.6
-
51
-
-
67449085093
-
Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis
-
Gao H, Lu Q, Liu X, Cong H, Zhao L, Wang H, et al. Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis. Cancer Sci 2009;100:782-5.
-
(2009)
Cancer Sci
, vol.100
, pp. 782-785
-
-
Gao, H.1
Lu, Q.2
Liu, X.3
Cong, H.4
Zhao, L.5
Wang, H.6
-
52
-
-
80155205757
-
Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling
-
Patterson AD, Maurhofer O, Beyoglu D, Lanz C, Krausz KW, Pabst T, et al. Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling. Cancer Res 2011;71:6590-600.
-
(2011)
Cancer Res
, vol.71
, pp. 6590-6600
-
-
Patterson, A.D.1
Maurhofer, O.2
Beyoglu, D.3
Lanz, C.4
Krausz, K.W.5
Pabst, T.6
-
53
-
-
79953687716
-
Urinary metabolic biomarkers of hepatocellular carcinoma in an Egyptian population: A validation study
-
Shariff MI, Gomaa AI, Cox IJ, Patel M, Williams HR, Crossey MM, et al. Urinary metabolic biomarkers of hepatocellular carcinoma in an Egyptian population: A validation study. J Proteome Res 2011;10:1828-36.
-
(2011)
J Proteome Res
, vol.10
, pp. 1828-1836
-
-
Shariff, M.I.1
Gomaa, A.I.2
Cox, I.J.3
Patel, M.4
Williams, H.R.5
Crossey, M.M.6
-
54
-
-
56149092963
-
A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry
-
Xue R, Lin Z, Deng C, Dong L, Liu T, Wang J, et al. A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom 2008;22:3061-8.
-
(2008)
Rapid Commun Mass Spectrom
, vol.22
, pp. 3061-3068
-
-
Xue, R.1
Lin, Z.2
Deng, C.3
Dong, L.4
Liu, T.5
Wang, J.6
-
55
-
-
34547171180
-
1H NMR spectroscopy in conjunction with multivariate data analysis
-
DOI 10.1021/pr070063h
-
Yang Y, Li C, Nie X, Feng X, Chen W, Yue Y, et al. Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning 1H NMR spectroscopy in conjunction with multivariate data analysis. J Proteome Res 2007;6:2605-14. (Pubitemid 47122355)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.7
, pp. 2605-2614
-
-
Yang, Y.1
Li, C.2
Nie, X.3
Feng, X.4
Chen, W.5
Yue, Y.6
Tang, H.7
Deng, F.8
-
56
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010;60:277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
58
-
-
80052945596
-
Urine metabolomics for kidney cancer detection and biomarker discovery
-
Ganti S, Weiss RH. Urine metabolomics for kidney cancer detection and biomarker discovery. Urol Oncol 2011;29:551-7.
-
(2011)
Urol Oncol
, vol.29
, pp. 551-557
-
-
Ganti, S.1
Weiss, R.H.2
-
59
-
-
63049134550
-
Urine metabolomics analysis for kidney cancer detection and biomarker discovery
-
Kim K, Aronov P, Zakharkin SO, Anderson D, Perroud B, Thompson IM, et al. Urine metabolomics analysis for kidney cancer detection and biomarker discovery. Mol Cell Proteomics 2009;8:558-70.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 558-570
-
-
Kim, K.1
Aronov, P.2
Zakharkin, S.O.3
Anderson, D.4
Perroud, B.5
Thompson, I.M.6
-
60
-
-
33947216093
-
A comprehensive urinary metabolomic approach for identifying kidney cancerr
-
DOI 10.1016/j.ab.2007.01.028, PII S0003269707000437
-
Kind T, Tolstikov V, Fiehn O, Weiss RH. A comprehensive urinary metabolomic approach for identifying kidney cancerr. Anal Biochem 2007;363:185-95. (Pubitemid 46428214)
-
(2007)
Analytical Biochemistry
, vol.363
, Issue.2
, pp. 185-195
-
-
Kind, T.1
Tolstikov, V.2
Fiehn, O.3
Weiss, R.H.4
-
61
-
-
79956159637
-
Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer
-
Kim K, Taylor SL, Ganti S, Guo L, Osier MV, Weiss RH. Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer. OMICS 2011;15:293-30.
-
(2011)
OMICS
, vol.15
, pp. 293-330
-
-
Kim, K.1
Taylor, S.L.2
Ganti, S.3
Guo, L.4
Osier, M.V.5
Weiss, R.H.6
-
62
-
-
84858050477
-
Urinary acylcarnitines are altered in human kidney cancer
-
Ganti S, Taylor SL, Kim K, Hoppel CL, Guo L, Yang J, et al. Urinary acylcarnitines are altered in human kidney cancer. Int J Cancer 2012;130:2791-800.
-
(2012)
Int J Cancer
, vol.130
, pp. 2791-2800
-
-
Ganti, S.1
Taylor, S.L.2
Kim, K.3
Hoppel, C.L.4
Guo, L.5
Yang, J.6
-
63
-
-
79952436750
-
LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery
-
Lin L, Huang Z, Gao Y, Yan X, Xing J, Hang W. LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery. J Proteome Res 2011;10:1396-405.
-
(2011)
J Proteome Res
, vol.10
, pp. 1396-1405
-
-
Lin, L.1
Huang, Z.2
Gao, Y.3
Yan, X.4
Xing, J.5
Hang, W.6
-
64
-
-
48949097374
-
Metabonomic profiling of renal cell carcinoma: High-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis
-
Gao H, Dong B, Liu X, Xuan H, Huang Y, Lin D. Metabonomic profiling of renal cell carcinoma: High-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis. Anal Chim Acta 2008;624:269-77.
-
(2008)
Anal Chim Acta
, vol.624
, pp. 269-277
-
-
Gao, H.1
Dong, B.2
Liu, X.3
Xuan, H.4
Huang, Y.5
Lin, D.6
-
65
-
-
77955456419
-
(1) H NMR metabonomic analysis in renal cell carcinoma: A possible diagnostic tool
-
Zira AN, Theocharis SE, Mitropoulos D, Migdalis V, Mikros E. (1) H NMR metabonomic analysis in renal cell carcinoma: A possible diagnostic tool. J Proteome Res 2010;9:4038-44.
-
(2010)
J Proteome Res
, vol.9
, pp. 4038-4044
-
-
Zira, A.N.1
Theocharis, S.E.2
Mitropoulos, D.3
Migdalis, V.4
Mikros, E.5
-
66
-
-
78751698400
-
Metabolic profiling reveals key metabolic features of renal cell carcinoma
-
Catchpole G, Platzer A, Weikert C, Kempkensteffen C, Johannsen M, Krause H, et al. Metabolic profiling reveals key metabolic features of renal cell carcinoma. J Cell Mol Med 2011;15:109-18.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 109-118
-
-
Catchpole, G.1
Platzer, A.2
Weikert, C.3
Kempkensteffen, C.4
Johannsen, M.5
Krause, H.6
-
67
-
-
84862302876
-
Application of ex vivo (1) H NMR metabonomics to the characterization and possible detection of renal cell carcinoma metastases
-
Gao H, Dong B, Jia J, Zhu H, Diao C, Yan Z, et al. Application of ex vivo (1) H NMR metabonomics to the characterization and possible detection of renal cell carcinoma metastases. J Cancer Res Clin Oncol 2012;138:753-61.
-
(2012)
J Cancer Res Clin Oncol
, vol.138
, pp. 753-761
-
-
Gao, H.1
Dong, B.2
Jia, J.3
Zhu, H.4
Diao, C.5
Yan, Z.6
-
68
-
-
0032893756
-
Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells
-
Aboagye EO, Bhujwalla ZM. Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cells. Cancer Res 1999;59:80-4. (Pubitemid 29062961)
-
(1999)
Cancer Research
, vol.59
, Issue.1
, pp. 80-84
-
-
Aboagye, E.O.1
Bhujwalla, Z.M.2
-
69
-
-
0036531816
-
Metabolic markers of breast cancer: Enhanced choline metabolism and reduced choline-ether-phospholipid synthesis
-
Katz-Brull R, Seger D, Rivenson-Segal D, Rushkin E, Degani H. Metabolic markers of breast cancer: Enhanced choline metabolism and reduced choline-ether-phospholipid synthesis. Cancer Res 2002;62:1966-70. (Pubitemid 34408439)
-
(2002)
Cancer Research
, vol.62
, Issue.7
, pp. 1966-1970
-
-
Katz-Brull, R.1
Seger, D.2
Rivenson-Segal, D.3
Rushkin, E.4
Degani, H.5
-
70
-
-
3042562283
-
Molecalar causes of tile aberrant choline phospholipid metabolism in breast cancer
-
DOI 10.1158/0008-5472.CAN-03-3829
-
Glunde K, Jie C, Bhujwalla ZM. Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res 2004;64:4270-6. (Pubitemid 38802433)
-
(2004)
Cancer Research
, vol.64
, Issue.12
, pp. 4270-4276
-
-
Glunde, K.1
Jie, C.2
Bhujwalla, Z.M.3
-
71
-
-
79958179526
-
Uncovering the metabolomic fingerprint of breast cancer
-
Oakman C, Tenori L, Biganzoli L, Santarpia L, Cappadona S, Luchinat C, et al. Uncovering the metabolomic fingerprint of breast cancer. Int J Biochem Cell Biol 2011;43:1010-20.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 1010-1020
-
-
Oakman, C.1
Tenori, L.2
Biganzoli, L.3
Santarpia, L.4
Cappadona, S.5
Luchinat, C.6
-
72
-
-
84872179913
-
Targeting Metabolomics in Breast Cancer
-
Oakman C, Tenori L, Cappadona S S, Luchinat C, Bertini I, Leo A. Targeting Metabolomics in Breast Cancer. Curr Breast Cancer Rep 2012;4:249-56.
-
(2012)
Curr Breast Cancer Rep
, vol.4
, pp. 249-256
-
-
Oakman, C.1
Tenori, L.2
Cappadona, S.S.3
Luchinat, C.4
Bertini, I.5
Leo, A.6
-
73
-
-
78650375977
-
Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers
-
Slupsky CM, Steed H, Wells TH, Dabbs K, Schepansky A, Capstick V, et al. Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers. Clin Cancer Res 2010;16:5835-41.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5835-5841
-
-
Slupsky, C.M.1
Steed, H.2
Wells, T.H.3
Dabbs, K.4
Schepansky, A.5
Capstick, V.6
-
74
-
-
78449285472
-
Early detection of recurrent breast cancer using metabolite profiling
-
Asiago VM, Alvarado LZ, Shanaiah N, Gowda GA, Owusu-Sarfo K, Ballas RA, et al. Early detection of recurrent breast cancer using metabolite profiling. Cancer Res 2010;70:8309-18.
-
(2010)
Cancer Res
, vol.70
, pp. 8309-8318
-
-
Asiago, V.M.1
Alvarado, L.Z.2
Shanaiah, N.3
Gowda, G.A.4
Owusu-Sarfo, K.5
Ballas, R.A.6
-
75
-
-
79957798468
-
Identification of a serum-detectable metabolomic fingerprint potentially correlated with the presence of micrometastatic disease in early breast cancer patients at varying risks of disease relapse by traditional prognostic methods
-
Oakman C, Tenori L, Claudino WM, Cappadona S, Nepi S, Battaglia A, et al. Identification of a serum-detectable metabolomic fingerprint potentially correlated with the presence of micrometastatic disease in early breast cancer patients at varying risks of disease relapse by traditional prognostic methods. Ann Oncol 2011;22:1295-301.
-
(2011)
Ann Oncol
, vol.22
, pp. 1295-1301
-
-
Oakman, C.1
Tenori, L.2
Claudino, W.M.3
Cappadona, S.4
Nepi, S.5
Battaglia, A.6
-
76
-
-
78651355465
-
Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer
-
Gu H, Pan Z, Xi B, Asiago V, Musselman B, Raftery D. Principal component directed partial least squares analysis for combining nuclear magnetic resonance and mass spectrometry data in metabolomics: Application to the detection of breast cancer. Anal Chim Acta 2011;686:57-63.
-
(2011)
Anal Chim Acta
, vol.686
, pp. 57-63
-
-
Gu, H.1
Pan, Z.2
Xi, B.3
Asiago, V.4
Musselman, B.5
Raftery, D.6
-
77
-
-
80054765285
-
An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy
-
Li M, Song Y, Cho N, Chang JM, Koo HR, Yi A, et al. An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy. PLoS One 2011;6:e25563.
-
(2011)
PLoS One
, vol.6
-
-
Li, M.1
Song, Y.2
Cho, N.3
Chang, J.M.4
Koo, H.R.5
Yi, A.6
-
79
-
-
19944426814
-
1H-NMR-based metabonomics
-
DOI 10.1002/ijc.20651
-
Odunsi K, Wollman RM, Ambrosone CB, Hutson A, McCann SE, Tammela J, et al. Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics. Int J Cancer 2005;113:782-8. (Pubitemid 40101260)
-
(2005)
International Journal of Cancer
, vol.113
, Issue.5
, pp. 782-788
-
-
Odunsi, K.1
Wollman, R.M.2
Ambrosone, C.B.3
Hutson, A.4
McCann, S.E.5
Tammela, J.6
Geisler, J.P.7
Miller, G.8
Sellers, T.9
Cliby, W.10
Qian, F.11
Keitz, B.12
Intengan, M.13
Lele, S.14
Alderfer, J.L.15
-
80
-
-
84874067623
-
Identification of potential biomarkers for ovarian cancer by urinary metabolomic profiling
-
Zhang T, Wu X, Ke C, Yin M, Li Z, Fan L, et al. Identification of potential biomarkers for ovarian cancer by urinary metabolomic profiling. J Proteome Res 2013;12:505-12.
-
(2013)
J Proteome Res
, vol.12
, pp. 505-512
-
-
Zhang, T.1
Wu, X.2
Ke, C.3
Yin, M.4
Li, Z.5
Fan, L.6
-
81
-
-
84872322570
-
A Metabonomics Study of Colorectal Cancer by RRLC-QTOF/MS
-
Yue H, Wang Y, Zhang Y, Ren H, Wu J, Ma L, et al. A Metabonomics Study of Colorectal Cancer by RRLC-QTOF/MS. J Liq Chromatogr Relat Technol 2013;36:428-38.
-
(2013)
J Liq Chromatogr Relat Technol
, vol.36
, pp. 428-438
-
-
Yue, H.1
Wang, Y.2
Zhang, Y.3
Ren, H.4
Wu, J.5
Ma, L.6
-
82
-
-
84863844396
-
A novel serum metabolomics-based diagnostic approach for colorectal cancer
-
Nishiumi S, Kobayashi T, Ikeda A, Yoshie T, Kibi M, Izumi Y, et al. A novel serum metabolomics-based diagnostic approach for colorectal cancer. PLoS One 2012;7:e40459.
-
(2012)
PLoS One
, vol.7
-
-
Nishiumi, S.1
Kobayashi, T.2
Ikeda, A.3
Yoshie, T.4
Kibi, M.5
Izumi, Y.6
-
83
-
-
60849139445
-
Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS)
-
Chan EC, Koh PK, Mal M, Cheah PY, Eu KW, Backshall A, et al. Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). J Proteome Res 2009;8:352-61.
-
(2009)
J Proteome Res
, vol.8
, pp. 352-361
-
-
Chan, E.C.1
Koh, P.K.2
Mal, M.3
Cheah, P.Y.4
Eu, K.W.5
Backshall, A.6
-
84
-
-
70350028279
-
Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS
-
Qiu Y, Cai G, Su M, Chen T, Zheng X, Xu Y, et al. Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J Proteome Res 2009;8:4844-50.
-
(2009)
J Proteome Res
, vol.8
, pp. 4844-4850
-
-
Qiu, Y.1
Cai, G.2
Su, M.3
Chen, T.4
Zheng, X.5
Xu, Y.6
-
85
-
-
77949822339
-
Urinary metabonomic study on colorectal cancer
-
Qiu Y, Cai G, Su M, Chen T, Liu Y, Xu Y, et al. Urinary metabonomic study on colorectal cancer. J Proteome Res 2010;9:1627-34.
-
(2010)
J Proteome Res
, vol.9
, pp. 1627-1634
-
-
Qiu, Y.1
Cai, G.2
Su, M.3
Chen, T.4
Liu, Y.5
Xu, Y.6
-
86
-
-
84872654995
-
Plasma choline-containing phospholipids: Potential biomarkers for colorectal cancer progression
-
Li S, Guo B, Song J, Deng X, Cong Y, Li P, et al. Plasma choline-containing phospholipids: potential biomarkers for colorectal cancer progression. Metabolomics 2013;9:202-12.
-
(2013)
Metabolomics
, vol.9
, pp. 202-212
-
-
Li, S.1
Guo, B.2
Song, J.3
Deng, X.4
Cong, Y.5
Li, P.6
-
87
-
-
79955930111
-
Prediction of gastric cancer metastasis through urinary metabolomic investigation using GC/MS
-
Hu JD, Tang HQ, Zhang Q, Fan J, Hong J, Gu JZ, et al. Prediction of gastric cancer metastasis through urinary metabolomic investigation using GC/MS. World J Gastroenterol 2011;17:727-34.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 727-734
-
-
Hu, J.D.1
Tang, H.Q.2
Zhang, Q.3
Fan, J.4
Hong, J.5
Gu, J.Z.6
-
88
-
-
84855390232
-
Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer
-
Bertini I, Cacciatore S, Jensen BV, Schou JV, Johansen JS, Kruhøffer M, et al. Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer. Cancer Res 2012;72:356-64.
-
(2012)
Cancer Res
, vol.72
, pp. 356-364
-
-
Bertini, I.1
Cacciatore, S.2
Jensen, B.V.3
Schou, J.V.4
Johansen, J.S.5
Kruhøffer, M.6
-
89
-
-
77951242628
-
Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model
-
Lu X, Bennet B, Mu E, Rabinowitz J, Kang Y. Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model. J Biol Chem 2010;285:9317-21.
-
(2010)
J Biol Chem
, vol.285
, pp. 9317-9321
-
-
Lu, X.1
Bennet, B.2
Mu, E.3
Rabinowitz, J.4
Kang, Y.5
-
90
-
-
84867527930
-
An NMR metabolomics approach for the diagnosis of leptomeningeal carcinomatosis
-
Cho HR, Wen H, Ryu YJ, An YJ, Kim HC, Moon WK, et al. An NMR metabolomics approach for the diagnosis of leptomeningeal carcinomatosis. Cancer Res 2012;72:5179-87.
-
(2012)
Cancer Res
, vol.72
, pp. 5179-5187
-
-
Cho, H.R.1
Wen, H.2
Ryu, Y.J.3
An, Y.J.4
Kim, H.C.5
Moon, W.K.6
-
91
-
-
78649944454
-
Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol
-
Thysell E, Surowiec I, Hörnberg E, Crnalic S, Widmark A, Johansson AI, et al. Metabolomic characterization of human prostate cancer bone metastases reveals increased levels of cholesterol. PLoS One 2010;5:e14175.
-
(2010)
PLoS One
, vol.5
-
-
Thysell, E.1
Surowiec, I.2
Hörnberg, E.3
Crnalic, S.4
Widmark, A.5
Johansson, A.I.6
-
92
-
-
78649334462
-
Serum metabolomics as a novel diagnostic approach for pancreatic cancer
-
Nishiumi S, Shinohara M, Ikeda A, Yoshie T, Hatano N, Kakuyama S, et al. Serum metabolomics as a novel diagnostic approach for pancreatic cancer. Metabolomics 2010;6:518-28.
-
(2010)
Metabolomics
, vol.6
, pp. 518-528
-
-
Nishiumi, S.1
Shinohara, M.2
Ikeda, A.3
Yoshie, T.4
Hatano, N.5
Kakuyama, S.6
-
93
-
-
33845314350
-
Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors
-
DOI 10.1158/0008-5472.CAN-06-0755
-
Denkert C, Budczies J, Kind T, Weichert W, Tablack P, Sehouli J, et al. Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res 2006;66:10795-804. (Pubitemid 44876975)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10795-10804
-
-
Denkert, C.1
Budczies, J.2
Kind, T.3
Weichert, W.4
Tablack, P.5
Sehouli, J.6
Niesporek, S.7
Konsgen, D.8
Dietel, M.9
Fiehn, O.10
-
94
-
-
84873397556
-
(1) H HR-MAS NMR Spectroscopy of Tumor Induced Local Metabolic "field-Effects" enables Colorectal Cancer Staging and Prognostication
-
Jimenez B, Mirnezami R, Kinross JM, Cloarec O, Keun HC, Holmes E, et al.(1) H HR-MAS NMR Spectroscopy of Tumor Induced Local Metabolic "Field-Effects" enables Colorectal Cancer Staging and Prognostication. J Proteome Res 2012;12:959-68.
-
(2012)
J Proteome Res
, vol.12
, pp. 959-968
-
-
Jimenez, B.1
Mirnezami, R.2
Kinross, J.M.3
Cloarec, O.4
Keun, H.C.5
Holmes, E.6
-
95
-
-
84858631197
-
Pharmaco-metabolomics: An emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets
-
Corona G, Rizzolio F, Giordano A, Toffoli G. Pharmaco-metabolomics: An emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets. J Cell Physiol 2012;227:2827-31.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2827-2831
-
-
Corona, G.1
Rizzolio, F.2
Giordano, A.3
Toffoli, G.4
-
96
-
-
33646198860
-
Pharmaco-metabonomic phenotyping and personalized drug treatment
-
Clayton TA, Lindon JC, Cloarec O, Antti H, Charuel C, Hanton G, et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 2006;440:1073-7.
-
(2006)
Nature
, vol.440
, pp. 1073-1077
-
-
Clayton, T.A.1
Lindon, J.C.2
Cloarec, O.3
Antti, H.4
Charuel, C.5
Hanton, G.6
-
97
-
-
34248139693
-
Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats
-
DOI 10.1021/pr060513q
-
Li H, Ni Y, Su M, Qiu Y, Zhou M, Qiu M, et al. Pharmacometabonomic phenotyping reveals different responses to xenobiotic intervention in rats. J Proteome Res 2007;6:1364-70. (Pubitemid 46724033)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.4
, pp. 1364-1370
-
-
Li, H.1
Ni, Y.2
Su, M.3
Qiu, Y.4
Zhou, M.5
Qiu, M.6
Zhao, A.7
Zhao, L.8
Jia, W.9
-
98
-
-
70149096873
-
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
-
Clayton TA, Baker D, Lindon JC, Everett JR, Nicholson JK. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proc Natl Acad Sci USA 2009;106:14728-33.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14728-14733
-
-
Clayton, T.A.1
Baker, D.2
Lindon, J.C.3
Everett, J.R.4
Nicholson, J.K.5
-
99
-
-
70349908127
-
Human urinary metabolomic profile of PPARalpha induced fatty acid beta-oxidation
-
Patterson AD, Slanar O, Krausz KW, Li F, Höfer CC, Perlík F, et al. Human urinary metabolomic profile of PPARalpha induced fatty acid beta-oxidation. J Proteome Res 2009;8:4293-300.
-
(2009)
J Proteome Res
, vol.8
, pp. 4293-4300
-
-
Patterson, A.D.1
Slanar, O.2
Krausz, K.W.3
Li, F.4
Höfer, C.C.5
Perlík, F.6
-
100
-
-
77954817641
-
Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics
-
West PR, Weir AM, Smith AM, Donley EL, Cezar GG. Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics. Toxicol Appl Pharmacol 2010;247:18-27.
-
(2010)
Toxicol Appl Pharmacol
, vol.247
, pp. 18-27
-
-
West, P.R.1
Weir, A.M.2
Smith, A.M.3
Donley, E.L.4
Cezar, G.G.5
-
101
-
-
78650434645
-
Pharmacometabonomics as an effector for personalized medicine
-
Nicholson JK, Wilson ID, Lindon JC. Pharmacometabonomics as an effector for personalized medicine. Pharmacogenomics 2011;12:103-11.
-
(2011)
Pharmacogenomics
, vol.12
, pp. 103-111
-
-
Nicholson, J.K.1
Wilson, I.D.2
Lindon, J.C.3
-
102
-
-
84863413686
-
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics
-
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, et al. Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: Selective serotonin reuptake inhibitor response pharmacogenomics. Pharmacogenet Genomics 2012;22:247-53.
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 247-253
-
-
Abo, R.1
Hebbring, S.2
Ji, Y.3
Zhu, H.4
Zeng, Z.B.5
Batzler, A.6
-
103
-
-
79955510058
-
Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine
-
Backshall A, Sharma R, Clarke SJ, Keun HC. Pharmacometabonomic profiling as a predictor of toxicity in patients with inoperable colorectal cancer treated with capecitabine. Clin Cancer Res 2011;17:3019-28.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3019-3028
-
-
Backshall, A.1
Sharma, R.2
Clarke, S.J.3
Keun, H.C.4
-
104
-
-
84864309412
-
Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: A pilot study
-
Tenori L, Oakman C, Claudino WM, Bernini P, Cappadona S, Nepi S, et al. Exploration of serum metabolomic profiles and outcomes in women with metastatic breast cancer: A pilot study. Mol Oncol 2012;6:437-44.
-
(2012)
Mol Oncol
, vol.6
, pp. 437-444
-
-
Tenori, L.1
Oakman, C.2
Claudino, W.M.3
Bernini, P.4
Cappadona, S.5
Nepi, S.6
-
105
-
-
34548841428
-
The Golm Metabolome Database: A database for GC-MS based metabolite profiling
-
Nielsen J, Jewett M, editors 1 ed. Leipzig, Germany: Springer Berlin Heidelberg
-
Hummel J, Selbig J, Walther D, Kopka J. The Golm Metabolome Database: a database for GC-MS based metabolite profiling. In: Nielsen J, Jewett M, editors. Metabolomics. 1 ed. Leipzig, Germany: Springer Berlin Heidelberg; 2007. p. 75-95.
-
(2007)
Metabolomics
, pp. 75-95
-
-
Hummel, J.1
Selbig, J.2
Walther, D.3
Kopka, J.4
-
106
-
-
84876148784
-
HMDB 3.0: The human metabolome database in 2013
-
Wishart DS, Jewison T, Guo AC, Wilson M, Knox C, Liu Y, et al. HMDB 3.0: The Human Metabolome Database in 2013. Nucleic Acids Res 2013;41:D801-7.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Wishart, D.S.1
Jewison, T.2
Guo, A.C.3
Wilson, M.4
Knox, C.5
Liu, Y.6
-
107
-
-
84855888813
-
Birmingham Metabolite Library: A publicly accessible database of 1-D H-1 and 2-D H-1 J-resolved NMR spectra of authentic metabolite standards (BML-NMR)
-
Ludwig C, Easton JM, Lodi A, Tiziani S, Manzoor SE, Southam AD, et al. Birmingham Metabolite Library: a publicly accessible database of 1-D H-1 and 2-D H-1 J-resolved NMR spectra of authentic metabolite standards (BML-NMR). Metabolomics 2012;8:8-18.
-
(2012)
Metabolomics
, vol.8
, pp. 8-18
-
-
Ludwig, C.1
Easton, J.M.2
Lodi, A.3
Tiziani, S.4
Manzoor, S.E.5
Southam, A.D.6
-
108
-
-
72449186517
-
FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry
-
Kind T, Wohlgemuth G, Lee do Y, Lu Y, Palazoglu M, Shahbaz S, et al. FiehnLib: Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Anal Chem 2009;81:10038-48.
-
(2009)
Anal Chem
, vol.81
, pp. 10038-10048
-
-
Kind, T.1
Wohlgemuth, G.2
Lee Do, Y.3
Lu, Y.4
Palazoglu, M.5
Shahbaz, S.6
-
109
-
-
34247163207
-
Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
-
Kind T, Fiehn O. Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry. BMC Bioinformatics 2007;8:105.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 105
-
-
Kind, T.1
Fiehn, O.2
-
110
-
-
84871433609
-
Global profiling strategies for mapping dysregulated metabolic pathways in cancer
-
Benjamin DI, Cravatt BF, Nomura DK. Global profiling strategies for mapping dysregulated metabolic pathways in cancer. Cell Metab 2012;16:565-77.
-
(2012)
Cell Metab
, vol.16
, pp. 565-577
-
-
Benjamin, D.I.1
Cravatt, B.F.2
Nomura, D.K.3
-
111
-
-
84855416488
-
Approaches for the study of cancer: Towards the integration of genomics, proteomics and metabolomics
-
Casado-Vela J, Cebrián A, Gómez del Pulgar MT, Lacal JC. Approaches for the study of cancer: Towards the integration of genomics, proteomics and metabolomics. Clin Transl Oncol 2011;13:617-28.
-
(2011)
Clin Transl Oncol
, vol.13
, pp. 617-628
-
-
Casado-Vela, J.1
Cebrián, A.2
Gómez Del Pulgar, M.T.3
Lacal, J.C.4
-
112
-
-
79953663708
-
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells
-
Cavill R, Kamburov A, Ellis JK, Athersuch TJ, Blagrove MS, Herwig R, et al. Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS Comput Biol 2011;7:e1001113.
-
(2011)
PLoS Comput Biol
, vol.7
-
-
Cavill, R.1
Kamburov, A.2
Ellis, J.K.3
Athersuch, T.J.4
Blagrove, M.S.5
Herwig, R.6
-
113
-
-
78649681933
-
Merging transcriptomics and metabolomics: Advances in breast cancer profiling
-
Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, et al. Merging transcriptomics and metabolomics: Advances in breast cancer profiling. BMC Cancer 2010;10:628.
-
(2010)
BMC Cancer
, vol.10
, pp. 628
-
-
Borgan, E.1
Sitter, B.2
Lingjærde, O.C.3
Johnsen, H.4
Lundgren, S.5
Bathen, T.F.6
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