Microbial heterogeneity affects bioprocess robustness: Dynamic single-cell analysis contributes to understanding of microbial populations

Biotechnology Journal

Volumn 9, Issue 1, 2014, Pages 61-72

  Delvigne, Frank ^a   Goffin, Philippe ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b GSK   (Belgium)

Author keywords

Bioreactor heterogeneity; Microbial stress; Scale up; Single cell; Stress biosensor

Indexed keywords

AUTOMATED FLOW CYTOMETRY; BIOPROCESS CONTROL; MICROBIAL POPULATIONS; PROCESS CONDITION; PROCESS EQUIPMENTS; SCALE-UP; SINGLE CELLS; SINGLECELL ANALYSIS;

INVESTMENTS;

FLOW CYTOMETRY;

PROBIOTIC AGENT; RECOMBINANT PROTEIN;

ARTICLE; BIOPROCESS; BIOSENSOR; FLOW CYTOMETRY; LAB ON A CHIP; METABOLITE; MICROBIAL POPULATION DYNAMICS; MICROFLUIDICS; NONHUMAN; PRIORITY JOURNAL; SINGLE CELL ANALYSIS;

BIOREACTOR HETEROGENEITY; MICROBIAL STRESS; SCALE-UP; SINGLE CELL; STRESS BIOSENSOR;

BACTERIA; BIOLOGICAL MARKERS; BIOSENSING TECHNIQUES; FLOW CYTOMETRY; FUNGI; PHENOTYPE; SINGLE-CELL ANALYSIS; SOFTWARE; STRESS, PHYSIOLOGICAL;

EID: 84891956059     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201300119     Document Type: Article

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