Cell mass and cell cycle dynamics of an asynchronous budding yeast population: Experimental observations, flow cytometry data analysis, and multi-scale modeling

Biotechnology and Bioengineering

Volumn 110, Issue 3, 2013, Pages 812-826

  Fernandes, Rita Lencastre ^a   Carlquist, Magnus ^a,b   Lundin, Luisa ^c   Heins, Anna Lena ^a   Dutta, Abhishek ^d   Sørensen, Søren J ^c   Jensen, Anker D ^a   Nopens, Ingmar ^d   Lantz, Anna Eliasson ^a   Gernaey, Krist V ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Cell cycle; Flow cytometry; Multiscale modeling; Population balance model (PBM); Saccharomyces cerevisiae; Standardized data analysis; Total protein content

Indexed keywords

BATCH CULTIVATION; CELL BEHAVIORS; CELL CULTIVATION; CELL CYCLE; CELL MASS; CELL POPULATIONS; CELL SIZE; CO-EXISTING; EXPERIMENTAL OBSERVATION; HETEROGENEOUS POPULATIONS; MATHEMATICAL DESCRIPTIONS; MECHANISTIC MODELS; MICROBIAL CULTIVATION; MICROBIAL POPULATIONS; MODEL PREDICTION; MULTI-SCALE MODELING; MULTISCALE MODELS; PHENOTYPIC TRAITS; POPULATION BALANCE MODELS; TOTAL PROTEIN; UNSTRUCTURED MODEL;

CELL CULTURE; CELL PROLIFERATION; DYNAMICS; FLOW CYTOMETRY; POPULATION STATISTICS; YEAST;

CELLS;

ANIMAL CELL; ARTICLE; BATCH CELL CULTURE; CELL BUDDING; CELL CULTURE; CELL CYCLE PARAMETERS; CELL CYCLE PHASE; CELL FUNCTION; CELL POPULATION; CELL SIZE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DATA ANALYSIS; FLOW CYTOMETRY; FUNGAL STRAIN; FUNGUS GROWTH; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; POPULATION BALANCE MODEL; SACCHAROMYCES CEREVISIAE; YEAST;

CELL CYCLE; CELL SIZE; FLOW CYTOMETRY; MODELS, THEORETICAL; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 84872673703     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24749     Document Type: Article

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