Bacterial autoinduction: Looking outside the cell for new metabolic engineering targets

Microbial Cell Factories

Volumn 1, Issue , 2002, Pages

  DeLisa, Matthew P ^a,d   Bentley, William E ^b,c  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIOCIN; CARBAPENEM; PSEUDOMONIC ACID; RECOMBINANT PROTEIN;

BACTERIAL GENETICS; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; BIOFILM; BIOLUMINESCENCE; CELL COMMUNICATION; CELL FUNCTION; DENSITY; DRUG SYNTHESIS; METABOLIC ENGINEERING; MICROORGANISM; NONHUMAN; PRODUCTIVITY; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SPOROGENESIS; STAPHYLOCOCCUS INFECTION; STRESS;

BACTERIA (MICROORGANISMS);

EID: 0041969836     PISSN: 14752859     EISSN: None     Source Type: Journal    
DOI: 10.1186/1475-2859-1-5     Document Type: Review

References (91)

1. Nealson KH, Platt T and Hastings JW Cellular control of the synthesis and activity of the bacterial luminescent system. J Bacteriol 1970, 104:313-322
2. Nealson KH and Hastings JW Bacterial bioluminescence: its control and ecological significance. Microbiol Rev 1979, 43:496-518
3. Fuqua C and Greenberg EP Self perception in bacteria: quorum sensing with acylated homoserine lactones. Curr Opin Microbiol 1998, 1:183-189
4. Miller MB and Bassler BL Quorum sensing in bacteria. Annu Rev Microbiol 2001, 55:165-199
5. Williams P, Camara M, Hardman A, Swift S, Milton D, Hope VJ, Winzer K, Middleton B, Pritchard DI and Bycroft BW Quorum sensing and the population-dependent control of virulence. Philos Trans R Soc Lond B Biol Sci 2000, 355:667-680
6. Withers H, Swift S and Williams P Quorum sensing as an integral component of gene regulatory networks in Gram-negative bacteria. Curr Opin Microbiol 2001, 4:186-193
7. Bassler BL How bacteria talk to each other: regulation of gene expression by quorum sensing. Curr Opin Microbiol 1999, 2:582-587
8. Lazazzera BA, Solomon JM and Grossman AD An exported peptide functions intracellularly to contribute to cell density signaling in B. subtilis. Cell 1997, 89:917-925
9. Kleerebezem M, Quadri LE, Kuipers OP and de Vos WM Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol Microbiol 1997, 24:895-904
10. Lazazzera BA and Grossman AD The ins and outs of peptide signaling. Trends Microbiol 1998, 6:288-294
11. Haverstein L and Morrison DA Quorum sensing and peptide pheromones in Streptococcal competence for genetic transformation. In Cell-Cell Signaling in Bacteria (Edited by: Dunney GaW) SC: ASM Press 1999, 9-26
12. Solomon JM, Magnuson R, Srivastava A and Grossman AD Convergent sensing pathways mediate response to two extracellular competence factors in Bacillus subtilis. Genes Dev 1995, 9:547-558
13. Norvick R Regulation of pathogenicity in Staphylococcus aureus by a peptide-based density-sensing system. In Cell-Cell Signaling in Bacteria (Edited by: Dunney GaW) SC: ASM Press 1999, 129-146
14. Fuqua C, Winans SC and Greenberg EP Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators. Annu Rev Microbiol 1996, 50:727-751
15. Parsek MR and Greenberg EP Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc Natl Acad Sci U S A 2000, 97:8789-8793
16. Piper KR, Beck von Bodman S and Farrand SK Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction. Nature 1993, 362:448-450
17. Bassler BL, Wright M, Showalter RE and Silverman MR Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol 1993, 9:773-786
18. Bassler BL, Wright M and Silverman MR Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway. Mol Microbiol 1994, 13:273-286
19. Bassler BL, Greenberg EP and Stevens AM Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol 1997, 179:4043-4045
20. Cao JG and Meighen EA Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi. J Biol Chem 1989, 264:21670-21676
21. Surette MG, Miller MB and Bassler BL Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc Natl Acad Sci U S A 1999, 96:1639-1644
22. Freeman JA, Lilley BN and Bassler BL A genetic analysis of the functions of LuxN: a two-component hybrid sensor kinase that regulates quorum sensing in Vibrio harveyi. Mol Microbiol 2000, 35:139-149
23. Freeman JA and Bassler BL Sequence and function of LuxU: a two-component phosphorelay protein that regulates quorum sensing in Vibrio harveyi. J Bacteriol 1999, 181:899-906
24. Lilley BN and Bassler BL Regulation of quorum sensing in Vibrio harveyi by LuxO and sigma-54. Mol Microbiol 2000, 36:940-954
25. Miyamoto CM, Lin YH and Meighen EA Control of bioluminescence in Vibrio fischeri by the LuxO signal response regulator. Mol Microbiol 2000, 36:594-607
26. Lodge RM and Hinshelwood CN Physiochemical aspects of bacterial growth. Part IX. The lag phase of Bacteriol lactis aerogenes. J Chem Soc 1943, 213-219
27. Wang XD, de Boer PA and Rothfield LI A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli. EMBO J 1991, 10:3363-3372
28. Garcia-Lara J, Shang LH and Rothfield LI An extracellular factor regulates expression of sdiA, a transcriptional activator of cell division genes in Escherichia coli. J Bacteriol 1996, 178:2742-2748
29. Sitnikov DM, Schineller JB and Baldwin TO Control of cell division in Escherichia coli: regulation of transcription of ftsQA involves both rpoS and SdiA-mediated autoinduction. Proc Natl Acad Sci U S A 1996, 93:336-341
30. Withers HL and Nordstrom K Quorum-sensing acts at initiation of chromosomal replication in Escherichia coli. Proc Natl Acad Sci U S A 1998, 95:15694-15699
31. Baca-DeLancey RR, South MM, Ding X and Rather PN Escherichia coli genes regulated by cell-to-cell signaling. Proc Natl Acad Sci U S A 1999, 96:4610-4614
32. Weichart DH and Kell DB Characterization of an autostimulatory substance produced by Escherichia coli. Microbiology 2001, 147:1875-1885
33. Lyte M, Frank CD and Green BT Production of an autoinducer of growth by norepinephrine cultured Escherichia coli O157:H7. FEMS Microbiol Lett 1996, 139:155-159
34. Winzer K, Hardie KR and Williams P Bacterial cell-to-cell communication: sorry, can't talk now - gone to lunch! Curr Opin Microbiol 2002, 5:216-222
35. DeLisa MP, Wu CF, Wang L, Valdes JJ and Bentley WE DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. J Bacteriol 2001, 183:5239-5247
36. Surette MG and Bassler BL Quorum sensing in Escherichia coli and Salmonella typhimurium. Proc Natl Acad Sci U S A 1998, 95:7046-7050
37. Schauder S, Shokat K, Surette MG and Bassler BL The LuxS family of bacterial autoinducers: biosynthesis of a novel quorumsensing signal molecule. Mol Microbiol 2001, 41:463-476
38. Winzer K, Hardie KR, Burgess N, Doherty N, Kirke D, Holden MT, Linforth R, Cornell KA, Taylor AJ and Hill PJ LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology 2002, 148:909-922
39. Ruzheinikov SN, Das SK, Sedelnikova SE, Hartley A, Foster SJ, Horsburgh MJ, Cox AG, McCleod CW, Mekhalfia A and Blackburn GM The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS. J Mol Biol 2001, 313:111-122
40. Hilgers MT and Ludwig ML Crystal structure of the quorumsensing protein LuxS reveals a catalytic metal site. Proc Natl Acad Sci U S A 2001, 98:11169-11174
41. Lewis HA, Furlong EB, Laubert B, Eroshkina GA, Batiyenko Y, Adams JM, Bergseid MG, Marsh CD, Peat TS and Sanderson WE A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure (Camb) 2001, 9:527-537
42. Beeston AL and Surette MG pfs-Dependent Regulation of Autoinducer 2 Production in Salmonella enterica Serovar Typhimurium. J Bacteriol 2002, 184:3450-3456
43. Taga ME, Semmelhack JL and Bassler BL The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Mol Microbiol 2001, 42:777-793
44. Chen X, Schauder S, Potier N, Van Dorsselaer A, Pelczer I, Bassler BL and Hughson FM Structural identification of a bacterial quorum-sensing signal containing boron. Nature 2002, 415:545-549
45. Sperandio V, Mellies JL, Nguyen W, Shin S and Kaper JB Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A 1999, 96:15196-15201
46. Sperandio V, Torres AG, Giron JA and Kaper JB Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol 2001, 183:5187-5197
47. Sperandio V, Torres AG and Kaper JB Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli. Mol Microbiol 2002, 43:809-821
48. Sperandio V, Li CC and Kaper JB Quorum-sensing Escherichia coli regulator A: a regulator of the LysR family involved in the regulation of the locus of enterocyte effacement pathogenicity island in enterohemorrhagic E. coli. Infect Immun 2002, 70:3085-3093
49. Elvers KT and Park SF Quorum sensing in Campylobacter jejuni: detection of a luxS encoded signalling molecule. Microbiology 2002, 148:1475-1481
50. Joyce EA, Bassler BL and Wright A Evidence for a signaling system in Helicobacter pylori: detection of a luxS-encoded autoinducer. J Bacteriol 2000, 182:3638-3643
51. Lyon WR, Madden JC, Levin JC, Stein JL and Caparon MG Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes. Mol Microbiol 2001, 42:145-157
52. Burgess NA, Kirke DF, Williams P, Winzer K, Hardie KR, Meyers NL, Aduse-Opoku J, Curtis MA and Camara M LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence. Microbiology 2002, 148:763-772
53. Day WA Jr and Maurelli AT Shigella flexneri LuxS quorum-sensing system modulates virB expression but is not essential for virulence. Infect Immun 2001, 69:15-23
54. Winzer K, Sun YH, Green A, Delory M, Blackley D, Hardie KR, Baldwin TJ and Tang CM Role of Neisseria meningitidis luxS in cell-tocell signaling and bacteremic infection. Infect Immun 2002, 70:2245-2248
55. Winans SC Bacterial esperanto. Nat Struct Biol 2002, 9:83-84
56. Kirkpatrick C, Maurer LM, Oyelakin NE, Yoncheva YN, Maurer R and Slonczewski JL Acetate and formate stress: opposite responses in the proteome of Escherichia coli. J Bacteriol 2001, 183:6466-6477
57. DeLisa MP, Valdes JJ and Bentley WE Mapping stress-induced changes in autoinducer AI-2 production in chemostat-cultivated Escherichia coli K-12. J Bacteriol 2001, 183:2918-2928
58. DeLisa MP, Valdes JJ and Bentley WE Quorum signaling via AI-2 communicates the "Metabolic Burden" associated with heterologous protein production in Escherichia coli. Biotechnol Bioeng 2001, 75:439-450
59. Lazazzera BA Quorum sensing and starvation: signals for entry into stationary phase. Curr Opin Microbiol 2000, 3:177-182
60. Huisman GW and Kolter R Sensing starvation: a homoserine lactone - dependent signaling pathway in Escherichia coli. Science 1994, 265:537-539
61. Hengge-Aronis R Recent insights into the general stress response regulatory network in Escherichia coli. J Mol Microbiol Biotechnol 2002, 4:341-346
62. Mulvey MR, Switala J, Borys A and Loewen PC Regulation of transcription of katE and katF in Escherichia coli. J Bacteriol 1990, 172:6713-6720
63. Surette MG and Bassler BL Regulation of autoinducer production in Salmonella typhimurium. Mol Microbiol 1999, 31:585-595
64. Volf J, Sevcik M, Havlickova H, Sisak F, Damborsky J and Rychlik I Role of SdiA in Salmonella enterica serovar Typhimurium physiology and virulence. Arch Microbiol 2002, 178:94-101
65. Michael B, Smith JN, Swift S, Heffron F and Ahmer BM SdiA of Salmonella enterica is a LuxR homolog that detects mixed microbial communities. J Bacteriol 2001, 183:5733-5742
66. Kanamaru K, Tatsuno I, Tobe T and Sasakawa C SdiA, an Escherichia coli homologue of quorum-sensing regulators, controls the expression of virulence factors in enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol 2000, 38:805-816
67. Adar YY and Ulitzur S GroESL proteins facilitate binding of externally added inducer by LuxR protein-containing E. coli cells. J Biolumin Chemilumin 1993, 8:261-266
68. Pragai Z and Harwood CR Regulatory interactions between the Pho and sigma(B)-dependent general stress regulons of Bacillus subtilis. Microbiology 2002, 148:1593-1602
69. Weikert C, Sauer U and Bailey JE An Escherichia coli host strain useful for efficient overproduction of secreted recombinant protein. Biotechnol Bioeng 1998, 59:386-391
70. Weikert C, Canonaco F, Sauer U and Bailey JE Co-overexpression of RspAB improves recombinant protein production in Escherichia coli. Metab Eng 2000, 2:293-299
71. Bentley WE, Mirjalili N, Andersen DC, Kompala DS and Davis RH Plasmid encoded protein: The principal factor in the "metabolic burden" associated with recombinant bacteria. Biotechnol Bioeng 1990, 35:668-681
72. Georgiou G Optimizing the production of recombinant proteins in microorganisms. AIChEJ 1988, 34:1233-1248
73. Cashel M and Rudd KE The stringent stress response. In Escherichia coli and Salmonella typhimurium (Edited by: Neidhardt FC, Ingraham JL, Low KB, Magasanik B, Schaechter M, Umbarger HE) American Society for Microbiology 1987, 2:
74. El-Sayed AK, Hothersall J and Thomas CM Quorum-sensing-dependent regulation of biosynthesis of the polyketide antibiotic mupirocin in Pseudomonas fluorescens NCIMB 10586. Microbiology 2001, 147:2127-2139
75. Quadri LE Regulation of antimicrobial peptide production by autoinducer-mediated quorum sensing in lactic acid bacteria. Antonie Van Leeuwenhoek 2002, 82:133-145
76. McGowan SJ, Holden MT, Bycroft BW and Salmond GP Molecular genetics of carbapenem antibiotic biosynthesis. Antonie Van Leeuwenhoek 1999, 75:135-141
77. Manefield M, Welch M, Givskov M, Salmond GP and Kjelleberg S Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora. FEMS Microbiol Lett 2001, 205:131-138
78. Derzelle S, Duchaud E, Kunst F, Danchin A and Bertin P Identification, characterization, and regulation of a cluster of genes involved in carbapenem biosynthesis in Photorhabdus luminescens. Appl Environ Microbiol 2002, 68:3780-3789
79. Stephanopoulos G and Vallino JJ Network rigidity and metabolic engineering in metabolite overproduction. Science 1991, 252:1675-1681
80. Liao JC, Hou S-Y and Chao Y-P Pathway analysis, engineering, and physiological considerations for redirecting central metabolism. Biotechnol Bioeng 1996, 52:129-140
81. Bailey JE Toward a science of metabolic engineering. Science 1991, 252:1668-1675
82. Meerman HJ and Georgiou G Construction and characterization of a set of E. coli strains deficient in all known loci affecting the proteolytic stability of secreted recombinant proteins. Biotechnology (N Y) 1994, 12:1107-1110
83. Srivastava R, Cha HJ, Peterson MS and Bentley WE Antisense downregulation of sigma(32) as a transient metabolic controller in Escherichia coli: effects on yield of active organophosphorus hydrolase. Appl Environ Microbiol 2000, 66:4366-4371
84. Kusano K, Waterman MR, Sakaguchi M, Omura T and Kagawa N Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli. Arch Biochem Biophys 1999, 367:129-136
85. Mujacic M, Cooper KW and Baneyx F Cold-inducible cloning vectors for low-temperature protein expression in Escherichia coli: application to the production of a toxic and proteolytically sensitive fusion protein. Gene 1999, 238:325-332
86. Gill R, DeLisa M, Valdes J and Bentley W Genomic analysis of high-cell-density recombinant Escherichia coli fermentation and " cell conditioning" for improved recombinant protein yield. Biotechnol Bioeng 2000, 72:85-95
87. Gill RT, Cha HJ, Jain A, Rao G and Bentley WE Generating controlled reducing environments in aerobic recombinant Escherichia coli fermentations: effects on cell growth, oxygen uptake, heat shock protein expression, and in vivo CAT activity. Biotechnol Bioeng 1998, 59:248-259
88. Bessette PH, Aslund F, Beckwith J and Georgiou G Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm. Proc Natl Acad Sci U S A 1999, 96:13703-13708
89. Lee CW and Shuler ML The effect of inoculum density and conditioned medium on the production of ajmalicine and catharanthine from immobilized Catharanthus roseus cells. Biotechnol Bioeng 2000, 67:61-71
90. Nozawa RT, Sekiguchi R and Yokota T Stimulation by conditioned medium of L-929 fibroblasts, E. coli lipopolysaccharide, and muramyl dipeptide of candidacidal activity of mouse macrophages. Cell Immunol 1980, 53:116-124
91. Bailey JE, Sburlati A, Hatzimanikatis V, Lee K, Renner WA and Tsai PS Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes. Biotechnol Bioeng 1996, 52:109-121