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Volumn 105, Issue 3, 2010, Pages 543-555

Genome-scale analysis of library sorting (GALibSo): Isolation of secretion enhancing factors for recombinant protein production in Pichia pastoris

Author keywords

Fab antibody fragment; Fluorescence activated cell sorting; Pichia pastoris; Recombinant protein production; Secretion enhancing factors; Surface display

Indexed keywords

ANTIBODY FRAGMENT; FLUORESCENCE ACTIVATED CELL SORTING; PICHIA PASTORIS; RECOMBINANT PROTEIN PRODUCTIONS; SURFACE DISPLAYS;

EID: 74849099399     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22573     Document Type: Article
Times cited : (32)

References (33)
  • 1
    • 0033601196 scopus 로고    scopus 로고
    • The action of N-terminal acetyltransferases on yeast ribosomal proteins
    • Arnold R, Polevoda B, Reilly J, Sherman F. 1999. The action of N-terminal acetyltransferases on yeast ribosomal proteins. J Biol Chem 274(52): 37035-37040.
    • (1999) J Biol Chem , vol.274 , Issue.52 , pp. 37035-37040
    • Arnold, R.1    Polevoda, B.2    Reilly, J.3    Sherman, F.4
  • 2
    • 33847669361 scopus 로고    scopus 로고
    • Using genomic microarrays to study insertional/ transposon mutant libraries
    • Baldwin D, Salama N. 2007. Using genomic microarrays to study insertional/ transposon mutant libraries. Methods Enzymol 421:90-110.
    • (2007) Methods Enzymol , vol.421 , pp. 90-110
    • Baldwin, D.1    Salama, N.2
  • 3
    • 0141533196 scopus 로고    scopus 로고
    • Co-expression of molecular chaperones does not improve the heterologous expression of mammalian Gprotein coupled receptor expression in yeast
    • Butz J, Niebauer R, Robinson A. 2003. Co-expression of molecular chaperones does not improve the heterologous expression of mammalian Gprotein coupled receptor expression in yeast. Biotechnol Bioeng 84(3):292-304.
    • (2003) Biotechnol Bioeng , vol.84 , Issue.3 , pp. 292-304
    • Butz, J.1    Niebauer, R.2    Robinson, A.3
  • 5
    • 36549073564 scopus 로고    scopus 로고
    • DNA-mediated transformation
    • Cregg JM. 2007. DNA-mediated transformation. Methods Mol Biol 389:27-42.
    • (2007) Methods Mol Biol , vol.389 , pp. 27-42
    • Cregg, J.M.1
  • 6
    • 33846841181 scopus 로고    scopus 로고
    • Cooverexpression of chaperones for enhanced secretion of a singlechain antibody fragment in Pichia pastoris
    • Damasceno L, Anderson K, Ritter G, Cregg J, Old L, Batt C. 2007. Cooverexpression of chaperones for enhanced secretion of a singlechain antibody fragment in Pichia pastoris. Appl Microbiol Biotechnol 74(2):381-389.
    • (2007) Appl Microbiol Biotechnol , vol.74 , Issue.2 , pp. 381-389
    • Damasceno, L.1    Anderson, K.2    Ritter, G.3    Cregg, J.4    Old, L.5    Batt, C.6
  • 9
    • 0026343673 scopus 로고
    • Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase
    • García-Alvarez N, Cueva R, Suárez-Rendueles P. 1991. Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase. Eur J Biochem 202(3):993-1002.
    • (1991) Eur J Biochem , vol.202 , Issue.3 , pp. 993-1002
    • García-Alvarez, N.1    Cueva, R.2    Suárez-Rendueles, P.3
  • 10
    • 33744499696 scopus 로고    scopus 로고
    • Engineering of Pichia pastoris for improved production of antibody fragments
    • Gasser B, Maurer M, Gach J, Kunert R, Mattanovich D. 2006. Engineering of Pichia pastoris for improved production of antibody fragments. Biotechnol Bioeng 94(2):353-361.
    • (2006) Biotechnol Bioeng , vol.94 , Issue.2 , pp. 353-361
    • Gasser, B.1    Maurer, M.2    Gach, J.3    Kunert, R.4    Mattanovich, D.5
  • 11
    • 35448965117 scopus 로고    scopus 로고
    • Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts
    • Gasser B, Sauer M, Maurer M, Stadlmayr G, Mattanovich D. 2007. Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts. Appl Environ Microbiol 73(20):6499-6507.
    • (2007) Appl Environ Microbiol , vol.73 , Issue.20 , pp. 6499-6507
    • Gasser, B.1    Sauer, M.2    Maurer, M.3    Stadlmayr, G.4    Mattanovich, D.5
  • 12
    • 42549105668 scopus 로고    scopus 로고
    • Gasser B, Saloheimo M, Rinas U, Dragosits M, Rodríguez-Carmona E, Baumann K, Giuliani M, Parrilli E, Branduardi P, Lang C, Porro D, Ferrer P, Tutino ML, Mattanovich D, Villaverde A. 2008a. Protein folding and conformational stress in microbial cells producing recombinant proteins: A host comparative overview. Microb Cell Fact 7:11. Gasser B, Mattanovich D, Sauer M, Stadlmayr G. 2008b. Expression System international patent application WO2008128701.
    • Gasser B, Saloheimo M, Rinas U, Dragosits M, Rodríguez-Carmona E, Baumann K, Giuliani M, Parrilli E, Branduardi P, Lang C, Porro D, Ferrer P, Tutino ML, Mattanovich D, Villaverde A. 2008a. Protein folding and conformational stress in microbial cells producing recombinant proteins: A host comparative overview. Microb Cell Fact 7:11. Gasser B, Mattanovich D, Sauer M, Stadlmayr G. 2008b. Expression System international patent application WO2008128701.
  • 13
  • 15
    • 36149001292 scopus 로고    scopus 로고
    • Glycosylation engineering in yeast: The advent of fully humanized yeast
    • Hamilton S, Gerngross T. 2007. Glycosylation engineering in yeast: The advent of fully humanized yeast. Curr Opin Biotechnol 18(5):387-392.
    • (2007) Curr Opin Biotechnol , vol.18 , Issue.5 , pp. 387-392
    • Hamilton, S.1    Gerngross, T.2
  • 16
    • 0442309687 scopus 로고    scopus 로고
    • Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris
    • Hohenblum H, Gasser B, Maurer M, Borth N, Mattanovich D. 2004. Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris. Biotechnol Bioeng 85(4):367-375.
    • (2004) Biotechnol Bioeng , vol.85 , Issue.4 , pp. 367-375
    • Hohenblum, H.1    Gasser, B.2    Maurer, M.3    Borth, N.4    Mattanovich, D.5
  • 17
    • 61449242817 scopus 로고    scopus 로고
    • Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology
    • Jacobs PP, Geysens S, Vervecken W, Contreras R, Callewaert N. 2009. Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology. Nat Protoc 4(1):58-70.
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 58-70
    • Jacobs, P.P.1    Geysens, S.2    Vervecken, W.3    Contreras, R.4    Callewaert, N.5
  • 18
    • 0036265376 scopus 로고    scopus 로고
    • Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation
    • Kuchin S, Vyas V, Carlson M. 2002. Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation. Mol Cell Biol 22(12):3994-4000.
    • (2002) Mol Cell Biol , vol.22 , Issue.12 , pp. 3994-4000
    • Kuchin, S.1    Vyas, V.2    Carlson, M.3
  • 19
    • 0032167410 scopus 로고    scopus 로고
    • Molecular characterization of five neutralizing anti-HIV type 1 antibodies: Identification of nonconventional D segments in the human monoclonal antibodies 2G12 and 2F5
    • Kunert R, Rüker F, Katinger H. 1998. Molecular characterization of five neutralizing anti-HIV type 1 antibodies: Identification of nonconventional D segments in the human monoclonal antibodies 2G12 and 2F5. AIDS Res Hum Retroviruses 14(13):1115-1128.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , Issue.13 , pp. 1115-1128
    • Kunert, R.1    Rüker, F.2    Katinger, H.3
  • 20
    • 10644247772 scopus 로고    scopus 로고
    • Improved secretory production of glucoamylase in Pichia pastoris by combination of genetic manipulations
    • Liu S, Chou W, Sheu C, Chang M. 2005. Improved secretory production of glucoamylase in Pichia pastoris by combination of genetic manipulations. Biochem Biophys Res Commun 326(4):817-824.
    • (2005) Biochem Biophys Res Commun , vol.326 , Issue.4 , pp. 817-824
    • Liu, S.1    Chou, W.2    Sheu, C.3    Chang, M.4
  • 21
    • 33845948161 scopus 로고    scopus 로고
    • SCALEs: Multiscale analysis of library enrichment
    • Lynch M, Warnecke T, Gill R. 2007. SCALEs: Multiscale analysis of library enrichment. Nat Methods 4(1):87-93.
    • (2007) Nat Methods , vol.4 , Issue.1 , pp. 87-93
    • Lynch, M.1    Warnecke, T.2    Gill, R.3
  • 22
    • 17244363998 scopus 로고    scopus 로고
    • Heterologous protein production using the Pichia pastoris expression system
    • Macauley-Patrick S, Fazenda M, McNeil B, Harvey L. 2005. Heterologous protein production using the Pichia pastoris expression system. Yeast 22(4):249-270.
    • (2005) Yeast , vol.22 , Issue.4 , pp. 249-270
    • Macauley-Patrick, S.1    Fazenda, M.2    McNeil, B.3    Harvey, L.4
  • 24
    • 0013329665 scopus 로고    scopus 로고
    • Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae
    • Park S, Koh S, Chun J, Hwang H, Kang H. 1999. Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. Mol Cell Biol 19(3):2044-2050.
    • (1999) Mol Cell Biol , vol.19 , Issue.3 , pp. 2044-2050
    • Park, S.1    Koh, S.2    Chun, J.3    Hwang, H.4    Kang, H.5
  • 25
    • 13644258042 scopus 로고    scopus 로고
    • Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation
    • Sauer M, Branduardi P, Gasser B, Valli M, Maurer M, Porro D, Mattanovich D. 2004. Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation. Microb Cell Fact 3(1):17.
    • (2004) Microb Cell Fact , vol.3 , Issue.1 , pp. 17
    • Sauer, M.1    Branduardi, P.2    Gasser, B.3    Valli, M.4    Maurer, M.5    Porro, D.6    Mattanovich, D.7
  • 26
    • 0031879861 scopus 로고    scopus 로고
    • Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments
    • Shusta E, Raines R, Plückthun A, Wittrup K. 1998. Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments. Nat Biotechnol 16(8):773-777.
    • (1998) Nat Biotechnol , vol.16 , Issue.8 , pp. 773-777
    • Shusta, E.1    Raines, R.2    Plückthun, A.3    Wittrup, K.4
  • 27
    • 0028326624 scopus 로고
    • Saccharomyces cerevisiae ribosomal protein L37 is encoded by duplicate genes that are differentially expressed
    • Tornow J, Santangelo G. 1994. Saccharomyces cerevisiae ribosomal protein L37 is encoded by duplicate genes that are differentially expressed. Curr Genet 25(6):480-487.
    • (1994) Curr Genet , vol.25 , Issue.6 , pp. 480-487
    • Tornow, J.1    Santangelo, G.2
  • 28
    • 13544253581 scopus 로고    scopus 로고
    • Engineering of a Pichia pastoris expression system for secretion of high amounts of intact human parathyroid hormone
    • Vad R, Nafstad E, Dahl L, Gabrielsen O. 2005. Engineering of a Pichia pastoris expression system for secretion of high amounts of intact human parathyroid hormone. J Biotechnol 116(3):251-260.
    • (2005) J Biotechnol , vol.116 , Issue.3 , pp. 251-260
    • Vad, R.1    Nafstad, E.2    Dahl, L.3    Gabrielsen, O.4
  • 29
    • 0037394871 scopus 로고    scopus 로고
    • Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae
    • Valkonen M, Penttilä M, Saloheimo M. 2003. Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 69(4):2065-2072.
    • (2003) Appl Environ Microbiol , vol.69 , Issue.4 , pp. 2065-2072
    • Valkonen, M.1    Penttilä, M.2    Saloheimo, M.3
  • 30
    • 0028676232 scopus 로고
    • New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
    • Wach A, Brachat A, Pöhlmann R, Philippsen P. 1994. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10(13):1793-1808.
    • (1994) Yeast , vol.10 , Issue.13 , pp. 1793-1808
    • Wach, A.1    Brachat, A.2    Pöhlmann, R.3    Philippsen, P.4
  • 31
    • 33847181688 scopus 로고    scopus 로고
    • A novel high-throughput screen reveals yeast genes that increase secretion of heterologous proteins
    • Wentz A, Shusta E. 2007. A novel high-throughput screen reveals yeast genes that increase secretion of heterologous proteins. Appl Environ Microbiol 73(4):1189-1198.
    • (2007) Appl Environ Microbiol , vol.73 , Issue.4 , pp. 1189-1198
    • Wentz, A.1    Shusta, E.2
  • 32
    • 33847624216 scopus 로고    scopus 로고
    • Screening transposon mutant libraries using full-genome oligonucleotide microarrays
    • Winterberg K, Reznikoff W. 2007. Screening transposon mutant libraries using full-genome oligonucleotide microarrays. Methods Enzymol 421:110-125.
    • (2007) Methods Enzymol , vol.421 , pp. 110-125
    • Winterberg, K.1    Reznikoff, W.2
  • 33
    • 18744388375 scopus 로고    scopus 로고
    • NRG1 is required for glucose repression of the SUC2 and GAL genes of Saccharomyces cerevisiae
    • Zhou H, Winston F. 2001. NRG1 is required for glucose repression of the SUC2 and GAL genes of Saccharomyces cerevisiae. BMC Genet 2:5.
    • (2001) BMC Genet , vol.2 , pp. 5
    • Zhou, H.1    Winston, F.2


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