메뉴 건너뛰기




Volumn 67, Issue 12, 2013, Pages 1234-1242

Omega-3 fatty acids: A review of the effects on adiponectin and leptin and potential implications for obesity management

Author keywords

adipokines; adiponectin; leptin

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; DOCOSAHEXAENOIC ACID; GLUCOSE; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; LEPTIN; OMEGA 3 FATTY ACID; PLACEBO; TUMOR NECROSIS FACTOR ALPHA;

EID: 84889582897     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2013.197     Document Type: Review
Times cited : (96)

References (120)
  • 1
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • DOI 10.1172/JCI29126
    • Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006; 116: 1784-1792 (Pubitemid 44033298)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 3
    • 0034739524 scopus 로고    scopus 로고
    • AHA dietary guidelines revision 2000 a statement for healthcare professionals from the nutrition committee of the american heart association
    • Krauss R, Eckel R, Howard B, Appel L, Daniels S, Deckelbaum R et al. AHA Dietary Guidelines Revision 2000: A statement for healthcare professionals from the nutrition committee of the American Heart Association. Circulation 2000; 102: 2284-2299
    • (2000) Circulation , vol.102 , pp. 2284-2299
    • Krauss, R.1    Eckel, R.2    Howard, B.3    Appel, L.4    Daniels, S.5    Deckelbaum, R.6
  • 4
    • 4344607526 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin
    • DOI 10.1373/clinchem.2004.032482
    • Meier U, Gressner A. Endocrine Regulation of Energy Metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin and resistin. Clin Chem 2004; 50: 1511-1525 (Pubitemid 39121218)
    • (2004) Clinical Chemistry , vol.50 , Issue.9 , pp. 1511-1525
    • Meier, U.1    Gressner, A.M.2
  • 6
    • 33749018531 scopus 로고    scopus 로고
    • Adiponectin is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction in patients presenting with chest pain
    • DOI 10.1093/eurheartj/ehl153
    • Cavusoglu E, Ruwende C, Chopra V, Yanamadala S, Eng C, Clark LT et al. Adiponectin is an independent predictor of all-cause mortality, cardiac mortality, and myocardial infarction in patients presenting with chest pain. Eur Heart J 2006; 27: 2300-2309 (Pubitemid 44453573)
    • (2006) European Heart Journal , vol.27 , Issue.19 , pp. 2300-2309
    • Cavusoglu, E.1    Ruwende, C.2    Chopra, V.3    Yanamadala, S.4    Eng, C.5    Clark, L.T.6    Pinsky, D.J.7    Marmur, J.D.8
  • 8
    • 2342538411 scopus 로고    scopus 로고
    • Leptin and hyperleptinemia - From friend to foe for cardiovascular function
    • DOI 10.1677/joe.0.1810001
    • Ren J. Leptin and hyperleptinemia - from friend to foe for cardiovascular function. J Endocrinol 2004; 181: 1-10 (Pubitemid 38584659)
    • (2004) Journal of Endocrinology , vol.181 , Issue.1 , pp. 1-10
    • Ren, J.1
  • 16
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • Frederich R, Hamann A, Anderson S, Lollmann V, Lowell B, Flier J. Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action. Nat Med 1995; 1: 1311-1314
    • (1995) Nat Med , vol.1 , pp. 1311-1314
    • Frederich, R.1    Hamann, A.2    Anderson, S.3    Lollmann, V.4    Lowell, B.5    Flier, J.6
  • 23
    • 66349096555 scopus 로고    scopus 로고
    • Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects
    • Madsen E, Bruun J, Skogstrand K, Hougaard D, Christiansen T, Richelsen B. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. Metabolism 2009; 58: 946-953
    • (2009) Metabolism , vol.58 , pp. 946-953
    • Madsen, E.1    Bruun, J.2    Skogstrand, K.3    Hougaard, D.4    Christiansen, T.5    Richelsen, B.6
  • 24
    • 0028958592 scopus 로고
    • Obesity Impairment of energy intake or of energy expenditure
    • Paris
    • Jequier E. Obesity. Impairment of energy intake or of energy expenditure. Ann Endocrinol (Paris) 1995; 56: 87-92
    • (1995) Ann Endocrinol , vol.56 , pp. 87-92
    • Jequier, E.1
  • 25
    • 0000659858 scopus 로고    scopus 로고
    • Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
    • DOI 10.1210/en.138.6.2569
    • Legradi G, Emerson CH, Ahima RS, Flier JS, Lechan RM. Leptin prevents fastinginduced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology 1997; 138: 2569-2576 (Pubitemid 27215264)
    • (1997) Endocrinology , vol.138 , Issue.6 , pp. 2569-2576
    • Legradi, G.1    Emerson, C.H.2    Ahima, R.S.3    Flier, J.S.4    Lechan, R.M.5
  • 26
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman J, Halass J. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-777
    • (1998) Nature , vol.395 , pp. 763-777
    • Friedman, J.1    Halass, J.2
  • 30
    • 0035684130 scopus 로고    scopus 로고
    • The prothrombotic effects of leptin possible implications for the risk of cardiovascular disease in obesity
    • discussion 41-42
    • Konstantinides S, Schafer K, Loskutoff DJ. The prothrombotic effects of leptin possible implications for the risk of cardiovascular disease in obesity. Ann NY Acad Sci 2001; 947: 134-141, discussion 41-2
    • (2001) Ann NY Acad Sci , vol.947 , pp. 134-141
    • Konstantinides, S.1    Schafer, K.2    Loskutoff, D.J.3
  • 32
    • 39449133732 scopus 로고    scopus 로고
    • Could the quality of dietary fat, and not just its quantity, be related to risk of obesity
    • DOI 10.1038/oby.2007.14, PII OBY200714
    • Moussavi N, Gavino V, Receveur O. Could the quality of dietary fat, and not just its quantity, be related to risk of obesity? Obesity 2008; 16: 7-15 (Pubitemid 351271943)
    • (2008) Obesity , vol.16 , Issue.1 , pp. 7-15
    • Moussavi, N.1    Gavino, V.2    Receveur, O.3
  • 33
    • 0020582667 scopus 로고
    • The effects of high and low energy density diets on satiety, energy intake, and eating time of obese and nonobese subjects
    • Duncan K, Bacon I, Weinsier R. The effects of high and low energy density diets on satiety, energy intake, and eating time of obese and nonobese subjects. Am J Clin Nutr 1983; 37: 763-767 (Pubitemid 13094859)
    • (1983) American Journal of Clinical Nutrition , vol.37 , Issue.5 , pp. 763-767
    • Duncan, K.H.1    Bacon, J.A.2    Weinsier, R.L.3
  • 35
    • 73349085284 scopus 로고    scopus 로고
    • Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity
    • Micallef M, Munro I, Phang M, Garg M. Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity. Brit J Nutr 2009; 102: 1370-1374
    • (2009) Brit J Nutr , vol.102 , pp. 1370-1374
    • Micallef, M.1    Munro, I.2    Phang, M.3    Garg, M.4
  • 38
    • 0034067493 scopus 로고    scopus 로고
    • The results of the GISSI-Prevenzione trial in the general framework of secondary prevention
    • DOI 10.1053/euhj.1999.1971
    • Marchioli R, Valagussa F. The results of the GISSI-Prevenzione trial in the general framework of secondary prevention. Eur Heart J 2000; 21: 949-952 (Pubitemid 30312078)
    • (2000) European Heart Journal , vol.21 , Issue.12 , pp. 949-952
    • Marchioli, R.1    Valagussa, F.2
  • 40
    • 33750141751 scopus 로고    scopus 로고
    • Fish intake, contaminants, and human health evaluating the risks and the benefits
    • Mozaffarian D, Rimm EB. Fish intake, contaminants, and human health: Evaluating the risks and the benefits. JAMA 2006; 296: 1885-1899 (Pubitemid 44596197)
    • (2006) Journal of the American Medical Association , vol.296 , Issue.15 , pp. 1885-1899
    • Mozaffarian, D.1    Rimm, E.B.2
  • 43
    • 84856477196 scopus 로고    scopus 로고
    • Department of Health and Human Services Hyattsville USA
    • US Department of Health and Human Services, Centers for Disease Control and PreventionHyattsville, USA, 2009
    • (2009) Centers for Disease Control and Prevention
  • 44
    • 84889594440 scopus 로고    scopus 로고
    • National Institutes Of Health Department of Health and Human Services: Bethesda, MD, USA
    • National Institutes of Health. Get the Facts: Omega-3 Supplements: An Introduction. Department of Health and Human Services: Bethesda, MD, USA, 2012
    • (2012) Get The Facts: Omega-3 Supplements: An Introduction
  • 45
    • 0032692793 scopus 로고    scopus 로고
    • Dietary fish as a major component of a weight-loss diet: Effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects
    • Mori T, Bao D, Burke V, Puddey I, Watts G, Beilin L. Dietary fish as a major component of a weight-loss diet: Effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am J Clin Nutr 1999; 70: 817-825 (Pubitemid 29512906)
    • (1999) American Journal of Clinical Nutrition , vol.70 , Issue.5 , pp. 817-825
    • Mori, T.A.1    Bao, D.Q.2    Burke, V.3    Puddey, I.B.4    Watts, G.F.5    Beilin, L.J.6
  • 46
    • 0032819001 scopus 로고    scopus 로고
    • Essential fatty acids in health and chronic disease
    • suppl
    • Simopoulos A. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999; 70(suppl): S560-S569
    • (1999) Am J Clin Nutr , vol.70
    • Simopoulos, A.1
  • 48
    • 12344253802 scopus 로고    scopus 로고
    • Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirin-triggered epimers
    • DOI 10.1007/s11745-004-1339-7
    • Serhan C, Arita M, Hong S, Gotlinger K. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their endogenous aspirintriggered epimers. Lipids 2004; 39: 1125-1132 (Pubitemid 40129055)
    • (2004) Lipids , vol.39 , Issue.11 , pp. 1125-1132
    • Serhan, C.N.1    Arita, M.2    Hong, S.3    Gotlinger, K.4
  • 49
    • 0038372423 scopus 로고    scopus 로고
    • Inhibition of activator protein-1 transcription factor activation by omega-3 fatty acid modulation of mitogen-activated protein kinase signaling kinases
    • Babcock T, Kurland A, Helton W, Rahman A, Anwar K, Espat N. Inhibition of activator protein-1 transcription factor activation by omega-3 fatty acid modulation of mitogen-activated protein kinase signaling kinases. Parenter Enteral Nutr 2003; 27: 176-180
    • (2003) Parenter Enteral Nutr , vol.27 , pp. 176-180
    • Babcock, T.1    Kurland, A.2    Helton, W.3    Rahman, A.4    Anwar, K.5    Espat, N.6
  • 50
    • 0030783119 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor α
    • DOI 10.1074/jbc.272.43.26827
    • Ren B, Thelen A, Peters J, Gonzalez F, Jump D. Polyunsaturated fatty acid suppression of hepatic fatty acid. Synthase and S14 gene expression does not require peroxisome proliferator-activated receptor alpha. J Biol Chem 1997; 272: 26827-26832 (Pubitemid 27452629)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.43 , pp. 26827-26832
    • Ren, B.1    Thelen, A.P.2    Peters, J.M.3    Gonzalez, F.J.4    Jump, D.B.5
  • 51
    • 39649111988 scopus 로고    scopus 로고
    • Omega-3 fatty acids and coronary heart disease risk: Clinical and mechanistic perspectives
    • Harris W, Miller M, Tighe A, Davidson M, Schaefer E. Omega-3 fatty acids and coronary heart disease risk: Clinical and mechanistic perspectives. Atherosclerosis 2008; 197: 12-24
    • (2008) Atherosclerosis , vol.197 , pp. 12-24
    • Harris, W.1    Miller, M.2    Tighe, A.3    Davidson, M.4    Schaefer, E.5
  • 52
    • 0027284492 scopus 로고
    • Does fish oil lower blood pressure? A meta-analysis of controlled trials
    • Morris M, Sacks F, Rosnerm B. Does fish oil lower blood pressuré A metaanalysis of controlled trials. Circulation 1993; 88: 523-533 (Pubitemid 23228051)
    • (1993) Circulation , vol.88 , Issue.2 , pp. 523-533
    • Morris, M.C.1    Sacks, F.2    Rosner, B.3
  • 53
    • 0027233392 scopus 로고
    • Does supplementation of diet with 'fish oil' reduce blood pressure? A meta-analysis of controlled clinical trials
    • DOI 10.1001/archinte.153.12.1429
    • Appel L, Miller E, Seidler A, Whelton P. Does supplementation of diet with 'fish oil' reduce blood pressuré A meta-analysis of controlled clinical trials. Arch Intern Med 1993; 153: 1429-1438 (Pubitemid 23191050)
    • (1993) Archives of Internal Medicine , vol.153 , Issue.12 , pp. 1429-1438
    • Appel, L.J.1    Miller III, E.R.2    Seidler, A.J.3    Whelton, P.K.4
  • 54
    • 0030974010 scopus 로고    scopus 로고
    • N-3 Fatty acids and serum lipoproteinsHuman studies
    • Harris W. n-3 Fatty acids and serum lipoproteinsHuman studies. Am J Clin Nutr 1997; 65: 1645-54S.
    • (1997) Am J Clin Nutr , vol.65
    • Harris, W.1
  • 55
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005; 352: 1685-1695
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.1
  • 56
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-A in human obesity and insulin resistance
    • Hotamisligil G, Arner P, Caro J, Atkinson R, Spiegelman B. Increased adipose tissue expression of tumor necrosis factor-a in human obesity and insulin resistance. J Clin Invest 1995; 95: 2409-2415
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.1    Arner, P.2    Caro, J.3    Atkinson, R.4    Spiegelman, B.5
  • 57
    • 57649217610 scopus 로고    scopus 로고
    • Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk
    • Kressel G, Trunz B, Bub A, Hulsmann O, Wolters M, Lichtinghagen R et al. Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis 2009; 202: 263-271
    • (2009) Atherosclerosis , vol.202 , pp. 263-271
    • Kressel, G.1    Trunz, B.2    Bub, A.3    Hulsmann, O.4    Wolters, M.5    Lichtinghagen, R.6
  • 58
    • 77956128186 scopus 로고    scopus 로고
    • Heart Foundation Australia Heart Foundation Australia 2008, [cited 25 May 2010 Available from
    • Heart Foundation Australia. Fish, fish oils, n-3 polyunsaturated fatty acids and cardiovascular health. Heart Foundation Australia 2008, [cited 25 May 2010]; Available from http://www.heartfoundation.org.au/SiteCollectionDocuments/ HW-FS-FishOils-PS-FINAL-web.pdf
    • Fish Fish Oils N-3 Polyunsaturated Fatty Acids And Cardiovascular Health
  • 59
    • 84866070612 scopus 로고    scopus 로고
    • Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis
    • Rizos E, Ntzani E, Bika E, Kostapanos M, Elisaf M. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis. JAMA 2012; 308: 1024-1033
    • (2012) JAMA , vol.308 , pp. 1024-1033
    • Rizos, E.1    Ntzani, E.2    Bika, E.3    Kostapanos, M.4    Elisaf, M.5
  • 60
    • 0036202812 scopus 로고    scopus 로고
    • Clinical nutrition: 4. Omega-3 fatty acids in cardiovascular care
    • Holub B. Clinical nutrition: Omega-3 fatty acids in cardiovascular care. CMAJ, 2002; 166: 608-615 (Pubitemid 34251494)
    • (2002) Canadian Medical Association Journal , vol.166 , Issue.5 , pp. 608-615
    • Holub, B.J.1
  • 62
    • 0015731243 scopus 로고
    • Diabetes mellitus in Eskimos after a decade
    • Mouratoff G, Scott E. Diabetes mellitus in Eskimos after a decade. JAMA 1973; 226: 1345-1346
    • (1973) JAMA , vol.226 , pp. 1345-1346
    • Mouratoff, G.1    Scott, E.2
  • 64
    • 0033659368 scopus 로고    scopus 로고
    • Prevalence of diabetes among Native Americans and Alaska Natives 1990
    • 1997: An increasing burden
    • Burrows N, Geiss L, Engelgau M, Acton K. Prevalence of diabetes among Native Americans and Alaska Natives, 1990-1997: An increasing burden. Diabetes Care 2000; 23: 1786-1790
    • (2000) Diabetes Care , vol.23 , pp. 1786-1790
    • Burrows, N.1    Geiss, L.2    Engelgau, M.3    Acton, K.4
  • 65
    • 0023623453 scopus 로고
    • Coronary heart disease, serum lipids, platelets and dietary fish in two communities in Northern Norway
    • Simonsen T, Vartun A, Lyngmo V, Nordoy A. Coronary heart disease, serum lipids, platelets and dietary fish in two communities in northern Norway. Acta Med Scand 1987; 222: 237-245 (Pubitemid 18020371)
    • (1987) Acta Medica Scandinavica , vol.222 , Issue.3 , pp. 237-245
    • Simonsen, T.1    Vartun, A.2    Lyngmo, V.3    Nordoy, A.4
  • 66
    • 0027988668 scopus 로고
    • Lower prevalence of impaired glucose tolerance and diabetes associated with daily seal oil or salmon consumption among Alaska natives
    • Adler A, Boyko E, Schraer C, Murphy N. Lower prevalence of impaired glucose tolerance and diabetes associated with daily seal oil or salmon consumption among Alaska Natives. Diab Care 1994; 17: 1498-1501 (Pubitemid 24369742)
    • (1994) Diabetes Care , vol.17 , Issue.12 , pp. 1498-1501
    • Adler, A.I.1    Boyko, E.J.2    Schraer, C.D.3    Murphy, N.J.4
  • 67
    • 0029083352 scopus 로고
    • Dietary factors determining diabetes and impaired glucose tolerance: A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study
    • Feskens E, Virtanen S, Rasanen L, Tuomilehto J, Stengard J, Pekkanen J et al. Dietary factors determining diabetes and impaired glucose tolerance: A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. Diab Care 1995; 18: 1104-1112
    • (1995) Diab Care , vol.18 , pp. 1104-1112
    • Feskens, E.1    Virtanen, S.2    Rasanen, L.3    Tuomilehto, J.4    Stengard, J.5    Pekkanen, J.6
  • 69
    • 33745305434 scopus 로고    scopus 로고
    • Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-γ-dependent mechanism in mice
    • DOI 10.2337/diabetes.55.04.06.db05-0985
    • Neschen S, Morino K, Rossbacher J, Pongratz R, Cline G, Sono S et al. Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptorgamma- dependent mechanism in mice. Diabetes 2006; 55: 924-928 (Pubitemid 44100165)
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 924-928
    • Neschen, S.1    Morino, K.2    Rossbacher, J.C.3    Pongratz, R.L.4    Cline, G.W.5    Sono, S.6    Gillum, M.7    Shulman, G.I.8
  • 70
    • 34247558036 scopus 로고    scopus 로고
    • Eicosapentaenoic acid actions on adiposity and insulin resistance in control and high-fat-fed rats:Rrole of apoptosis, adiponectinand tumour necrosis factor-α
    • DOI 10.1017/S0007114507207627, PII S0007114507207627
    • Pérez-Matute P, Pé rez-Echarri N, Marti?nez J, Marti A, Moreno-Aliaga M. Eicosapentaenoic acid actions on adiposity and insulin resistance in control and highfat- fed rats: Role of apoptosis, adiponectin and tumour necrosis factor-a. Br J Nutr 2007; 97: 389-398 (Pubitemid 46671814)
    • (2007) British Journal of Nutrition , vol.97 , Issue.2 , pp. 389-398
    • Perez-Matute, P.1    Perez-Echarri, N.2    Martinez, J.A.3    Marti, A.4    Moreno-Aliaga, M.J.5
  • 72
    • 77953927847 scopus 로고    scopus 로고
    • Dietary n-3:n-6 fatty acid ratios differentially influence hormonal signature in a rodent model of metabolic syndrome relative to healthy controls
    • Burghardt P, Kemmerer E, Buck B, Osetek A, Yan C, Koch L et al. Dietary n-3:n-6 fatty acid ratios differentially influence hormonal signature in a rodent model of metabolic syndrome relative to healthy controls. Nutr Metab 2010; 7: 1-6
    • (2010) Nutr Metab , vol.7 , pp. 1-6
    • Burghardt, P.1    Kemmerer, E.2    Buck, B.3    Osetek, A.4    Yan, C.5    Koch, L.6
  • 73
    • 34248393099 scopus 로고    scopus 로고
    • High-fat diets: Modeling the metabolic disorders of human obesity in rodents
    • Buettner R, Scholmerich J, Bollheimer L. High-fat diets: Modeling the metabolic disorders of human obesity in rodents. Obesity 2007; 15: 798-808 (Pubitemid 46740952)
    • (2007) Obesity , vol.15 , Issue.4 , pp. 798-808
    • Buettner, R.1    Scholmerich, J.2    Bollheimer, L.C.3
  • 74
    • 77954731863 scopus 로고    scopus 로고
    • Effects of a fish-based diet on the serum adiponectin concentration in young, non-obese, healthy Japanese subjects
    • Kondo K, Morino K, Nishio Y, Kondo M, Fuke T, Ugi S et al. Effects of a fish-based diet on the serum adiponectin concentration in young, non-obese, healthy Japanese subjects. J Atheroscler Thromb 2010; 17: 628-637
    • (2010) J Atheroscler Thromb , vol.17 , pp. 628-637
    • Kondo, K.1    Morino, K.2    Nishio, Y.3    Kondo, M.4    Fuke, T.5    Ugi, S.6
  • 75
    • 67549136395 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid on endothelial cell-derived microparticles, angiopoietins and adiponectin in patients with type 2 diabetes
    • Nomura S, Shouzu A, Omoto S, Inami N, Ueba T, Urase F et al. Effects of eicosapentaenoic acid on endothelial cell-derived microparticles, angiopoietins and adiponectin in patients with type 2 diabetes. J Atheroscler Thromb 2009; 16: 83-90
    • (2009) J Atheroscler Thromb , vol.16 , pp. 83-90
    • Nomura, S.1    Shouzu, A.2    Omoto, S.3    Inami, N.4    Ueba, T.5    Urase, F.6
  • 76
    • 84855962115 scopus 로고    scopus 로고
    • Low-dose fish oil supplementation increases serum adiponectin without affecting inflammatory markers in overweight subjects
    • Gammelmark A, Madsen T, Varming K, Lundbye-Christensen S, Schmidt E. Low-dose fish oil supplementation increases serum adiponectin without affecting inflammatory markers in overweight subjects. Nutr Res 2012; 32: 15-23
    • (2012) Nutr Res , vol.32 , pp. 15-23
    • Gammelmark, A.1    Madsen, T.2    Varming, K.3    Lundbye-Christensen, S.4    Schmidt, E.5
  • 77
    • 33845247319 scopus 로고    scopus 로고
    • Effects of omega-3 polyunsaturated fatty acids on metabolically active hormones in patients post-myocardial infarction
    • DOI 10.1016/j.ijcard.2006.04.004, PII S0167527306002865
    • Patel JV, Lee KW, Tomson J, Dubb K, Hughes EA, Lip GY. Effects of omega-3 polyunsaturated fatty acids on metabolically active hormones in patients post-myocardial infarction. Int J Cardiol 2007; 115: 42-45 (Pubitemid 44856752)
    • (2007) International Journal of Cardiology , vol.115 , Issue.1 , pp. 42-45
    • Patel, J.V.1    Lee, K.W.2    Tomson, J.3    Dubb, K.4    Hughes, E.A.5    Lip, G.Y.H.6
  • 80
    • 5044223159 scopus 로고    scopus 로고
    • Effect of fish diets and weight loss on serum leptin concentration in overweight, treated-hypertensive subjects
    • DOI 10.1097/00004872-200410000-00022
    • Mori TA, Burke V, Puddey IB, Shaw JE, Beilin LJ. Effect of fish diets and weight loss on serum leptin concentration in overweight, treated-hypertensive subjects. J Hypertens 2004; 22: 1983-1990 (Pubitemid 39336682)
    • (2004) Journal of Hypertension , vol.22 , Issue.10 , pp. 1983-1990
    • Mori, T.A.1    Burke, V.2    Puddey, I.B.3    Shaw, J.E.4    Beilin, L.J.5
  • 83
    • 0037233878 scopus 로고    scopus 로고
    • Serum ghrelin levels in obese patients: The relationship to serum leptin levels and soluble leptin receptors levels
    • Rosicka M, Krsek M, Matoulek M, Jarkovska Z, Marek J, Justova V et al. Serum ghrelin levels in obese patients: The relationship to serum leptin levels and soluble leptin receptors levels. Physiol Res 2003; 52: 61-66 (Pubitemid 36356261)
    • (2003) Physiological Research , vol.52 , Issue.1 , pp. 61-66
    • Rosicka, M.1    Krsek, M.2    Matoulek, M.3    Jarkovska, Z.4    Marek, J.5    Justova, V.6    Lacinova, Z.7
  • 84
    • 0032708248 scopus 로고    scopus 로고
    • The leptin-fat ratio is constant, and leptin may be part of two feedback mechanisms for maintaining the body fat set point in non-obese male fischer 344 rats
    • Greenberg JA, Boozer CN. The leptin-fat ratio is constant, and leptin may be part of two feedback mechanisms for maintaining the body fat set point in non-obese male Fischer 344 rats. Horm Metab Res 1999; 31: 525-532 (Pubitemid 29507832)
    • (1999) Hormone and Metabolic Research , vol.31 , Issue.9 , pp. 525-532
    • Greenberg, J.A.1    Boozer, C.N.2
  • 86
    • 0033303819 scopus 로고    scopus 로고
    • Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia
    • Ahima R, Kelly J, Elmquist J, Flier J. Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 1999; 140: 4923-4931
    • (1999) Endocrinology , vol.140 , pp. 4923-4931
    • Ahima, R.1    Kelly, J.2    Elmquist, J.3    Flier, J.4
  • 87
    • 84867833770 scopus 로고    scopus 로고
    • Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: A randomized controlled trial
    • Itariu B, Zeyda M, Hochbrugger E, Neuhofer A, Prager G, Schindler K et al. Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: A randomized controlled trial. Am J Clin Nutr 2012; 96: 1137-1149
    • (2012) Am J Clin Nutr , vol.96 , pp. 1137-1149
    • Itariu, B.1    Zeyda, M.2    Hochbrugger, E.3    Neuhofer, A.4    Prager, G.5    Schindler, K.6
  • 88
    • 84855950126 scopus 로고    scopus 로고
    • Significant differential effects of omega-3 fatty acids and fenofibrate in patients with hypertriglyceridemia
    • Koh K, Quon M, Shin K, Lim S, Lee Y, Sakuma I et al. Significant differential effects of omega-3 fatty acids and fenofibrate in patients with hypertriglyceridemia. Atherosclerosis 2012; 220: 537-544
    • (2012) Atherosclerosis , vol.220 , pp. 537-544
    • Koh, K.1    Quon, M.2    Shin, K.3    Lim, S.4    Lee, Y.5    Sakuma, I.6
  • 89
    • 84876669710 scopus 로고    scopus 로고
    • Shortterm effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults
    • Neale E, Muhlhausler B, Probst Y, Batterham M, Fernandez F, Tapsell L. Shortterm effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults. Metabolism 2013; 62: 651-660
    • (2013) Metabolism , vol.62 , pp. 651-660
    • Neale, E.1    Muhlhausler, B.2    Probst, Y.3    Batterham, M.4    Fernandez, F.5    Tapsell, L.6
  • 90
    • 0038359739 scopus 로고    scopus 로고
    • Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans
    • DOI 10.1210/jc.2002-021604
    • Yannakoulia M, Yiannakouris N, Blüher S, Matalas A, Klimis-Zacas D, Mantzoros C. Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J Clin Endocrino Metab 2003; 88: 1730-1736 (Pubitemid 36623396)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.4 , pp. 1730-1736
    • Yannakoulia, M.1    Yiannakouris, N.2    Bluher, S.3    Matalas, A.-L.4    Klimis-Zacas, D.5    Mantzoros, C.S.6
  • 91
    • 1442300762 scopus 로고    scopus 로고
    • Chronological changes in metabolism and functions of cultured adipocytes: A hypothesis for cell aging in mature adipocytes
    • Yu Y, Zhu H. Chronological changes in metabolism and functions of cultured adipocytes: A hypothesis for cell aging in mature adipocytes. Am J Physiol Endocrinol Metab 2004; 286: E402-E410 (Pubitemid 38292690)
    • (2004) American Journal of Physiology - Endocrinology and Metabolism , vol.286 , Issue.3
    • Yu, Y.-H.1    Zhu, H.2
  • 94
    • 0035798713 scopus 로고    scopus 로고
    • The mechanisms by which both heterozygous peroxisome proliferator- activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance
    • Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K et al. The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J Biol Chem 2001; 276: 41245-41254
    • (2001) J Biol Chem , vol.276 , pp. 41245-41254
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Murakami, K.4    Motojima, K.5    Komeda, K.6
  • 96
    • 20444477160 scopus 로고    scopus 로고
    • Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPARγ
    • DOI 10.1016/j.bcp.2005.04.022, PII S0006295205002509
    • Karbowska J, Kochan Z. Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPARg. Biochem Pharmacol 2005; 70: 249-257 (Pubitemid 40814407)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.2 , pp. 249-257
    • Karbowska, J.1    Kochan, Z.2
  • 98
    • 0037323424 scopus 로고    scopus 로고
    • Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy
    • DOI 10.1210/jc.2002-020795
    • Addy C, Gavrila A, Tsiodras S, Brodovicz K, Karchmer A, Mantzoros C. Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. J Clin Endocrino Metab 2003; 88: 627-636 (Pubitemid 36207802)
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.2 , pp. 627-636
    • Addy, C.L.1    Gavrila, A.2    Tsiodras, S.3    Brodovicz, K.4    Karchmer, A.W.5    Mantzoros, C.S.6
  • 99
    • 44849116310 scopus 로고    scopus 로고
    • The perfect storm: Obesity, adipocyte dysfunction, and metabolic consequences
    • DOI 10.1373/clinchem.2007.100156
    • Ferranti Sd, Mozaffarian D. The perfect storm: Obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem 2008; 54: 945-955 (Pubitemid 351793400)
    • (2008) Clinical Chemistry , vol.54 , Issue.6 , pp. 945-955
    • De Ferranti, S.1    Mozaffarian, D.2
  • 100
    • 70449533779 scopus 로고    scopus 로고
    • No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: A randomized controlled trial in healthy, middle-aged individuals
    • Pot G, Brouwer I, Enneman A, Rijkers G, Kampman E, Geelen A. No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: A randomized controlled trial in healthy, middle-aged individuals. Eu J Clin Nutr 2009; 63: 1353-1359
    • (2009) Eu J Clin Nutr , vol.63 , pp. 1353-1359
    • Pot, G.1    Brouwer, I.2    Enneman, A.3    Rijkers, G.4    Kampman, E.5    Geelen, A.6
  • 101
    • 0032817672 scopus 로고    scopus 로고
    • Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NFκB activity
    • DOI 10.1006/jsre.1998.5524
    • Lo C-J, Chiu KC, Fu M, Lo R, Helton S. Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NFkB activity. J Surg Res 1999; 82: 216-221 (Pubitemid 29394126)
    • (1999) Journal of Surgical Research , vol.82 , Issue.2 , pp. 216-221
    • Lo, C.-J.1    Chiu, K.C.2    Fu, M.3    Lo, R.4    Helton, S.5
  • 102
    • 0030981824 scopus 로고    scopus 로고
    • Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by ω3 polyunsaturated fatty acids
    • Ohata T, Fukuda K, Takahashi M, Sugimura T, Wakabayashi K. Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by omega 3 polyunsaturated fatty acids. Jpn J Cancer Res 1997; 88: 234-237 (Pubitemid 27170482)
    • (1997) Japanese Journal of Cancer Research , vol.88 , Issue.3 , pp. 234-237
    • Ohata, T.1    Fukuda, K.2    Takahashi, M.3    Sugimura, T.4    Wakabayashi, K.5
  • 105
    • 0025374441 scopus 로고
    • Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects
    • DOI 10.1002/art.1780330607
    • Kremer J, Lawrence D, Jubiz W, Di Giacomo R, Rynes R, Bartholomew L et al. Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. clinical and immunological effects. Arthritis Rheum 1990; 33: 810-820 (Pubitemid 20205760)
    • (1990) Arthritis and Rheumatism , vol.33 , Issue.6 , pp. 810-820
    • Kremer, J.M.1    Lawrence, D.A.2    Jubiz, W.3    DiGiacomo, R.4    Rynes, R.5    Bartholomew, L.E.6    Sherman, M.7
  • 106
    • 0031409193 scopus 로고    scopus 로고
    • Docosahexaenoic and eisosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6
    • Khalfoun B, Thibault F, Watier H, Bardos P, Lebranchu Y. Docosahexaenoic and eisosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6. Adv Exp Med Biol 1997; 400B: 589-597
    • (1997) Adv Exp Med Biol , vol.400 B , pp. 589-597
    • Khalfoun, B.1    Thibault, F.2    Watier, H.3    Bardos, P.4    Lebranchu, Y.5
  • 107
    • 0029978318 scopus 로고    scopus 로고
    • Endres S. n-3 Polyunsaturated fatty acids and human cytokine synthesis
    • Endres S. n-3 Polyunsaturated fatty acids and human cytokine synthesis. Lipids 1996; 31: S239-S242
    • (1996) Lipids , vol.31
  • 108
    • 0025782730 scopus 로고
    • Oral n-3 fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: Comparison in young and older women
    • Meydani S, Endres S, Woods M, Goldin B, Soo C, Morrill L et al. Oral n-3 fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: Comparison in young and older women. J Nutr 1991; 121: 547-555
    • (1991) J Nutr , vol.121 , pp. 547-555
    • Meydani, S.1    Endres, S.2    Woods, M.3    Goldin, B.4    Soo, C.5    Morrill, L.6
  • 109
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissue?
    • Yudkin J, Stehouwer C, Emeis J, Coppack S. C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissué Arterioscler Thromb Vasc Biol 1999; 19: 972-978 (Pubitemid 29177345)
    • (1999) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.19 , Issue.4 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.A.2    Emeis, J.J.3    Coppack, S.W.4
  • 114
    • 0035209720 scopus 로고    scopus 로고
    • Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals
    • DOI 10.1038/sj.ijo.0801825
    • van Dielen F, vant Veer C, Schols A, Soeters P, Buurman W, Greve J. Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals. Int J Obesity 2001; 25: 1759-1766 (Pubitemid 33131915)
    • (2001) International Journal of Obesity , vol.25 , Issue.12 , pp. 1759-1766
    • Van Dielen, F.M.H.1    Van't Veer, C.2    Schols, A.M.3    Soeters, P.B.4    Buurman, W.A.5    Greve, J.W.M.6
  • 115
    • 0033969577 scopus 로고    scopus 로고
    • Tumour necrosis factor-α exerts dual effects on human adipose leptin synthesis and release
    • DOI 10.1016/S0303-7207(99)00194-X, PII S030372079900194X
    • Zhang H, Kumar S, Barnett A, Eggo M. Tumor necrosis factor-a exerts dual effects on human adipose leptin synthesis and release. Mol Cell Endocrinol 1999; 159: 79-88 (Pubitemid 30067642)
    • (2000) Molecular and Cellular Endocrinology , vol.159 , Issue.1-2 , pp. 79-88
    • Zhang, H.H.1    Kumar, S.2    Barnett, A.H.3    Eggo, M.C.4
  • 116
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss and relationship to lipoprotein lipasa
    • Kern P, Saghizadeh M, Ong J, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss and relationship to lipoprotein lipasa. J Clin Invest 1995; 95: 2111-2119
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.1    Saghizadeh, M.2    Ong, J.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 118
    • 0344872784 scopus 로고    scopus 로고
    • Marine n-3 fatty acids and thrombosis
    • DOI 10.1016/j.thromres.2003.09.001
    • Schmidt E. Marine n-3 fatty acids and thrombosis. Thromb Res 2003; 111: 9-10 (Pubitemid 37485919)
    • (2003) Thrombosis Research , vol.111 , Issue.1-2 , pp. 9-10
    • Schmidt, E.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.