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Volumn 308, Issue 10, 2012, Pages 1024-1033

Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA 3 FATTY ACID;

EID: 84866070612     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/2012.jama.11374     Document Type: Review
Times cited : (882)

References (46)
  • 1
    • 0037161373 scopus 로고    scopus 로고
    • Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: Time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione
    • GISSI-Prevenzione Investigators
    • Marchioli R, Barzi F, Bomba E, et al; GISSI-Prevenzione Investigators. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation. 2002;105(16):1897-1903.
    • (2002) Circulation , vol.105 , Issue.16 , pp. 1897-1903
    • Marchioli, R.1    Barzi, F.2    Bomba, E.3
  • 2
    • 53049110571 scopus 로고    scopus 로고
    • Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): A randomised, double-blind, placebocontrolled trial
    • GISSIHF Investigators
    • Tavazzi L, Maggioni AP, Marchioli R, et al; GISSIHF Investigators. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebocontrolled trial. Lancet. 2008;372(9645):1223-1230.
    • (2008) Lancet , vol.372 , Issue.9645 , pp. 1223-1230
    • Tavazzi, L.1    Maggioni, A.P.2    Marchioli, R.3
  • 3
    • 33947583493 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients ( JELIS): A randomised open-label, blinded endpoint analysis
    • Japan EPA Lipid Intervention Study ( JELIS) Investigators
    • Yokoyama M, Origasa H, Matsuzaki M, et al; Japan EPA Lipid Intervention Study ( JELIS) Investigators. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients ( JELIS): a randomised open-label, blinded endpoint analysis. Lancet. 2007;369(9567):1090-1098.
    • (2007) Lancet , vol.369 , Issue.9567 , pp. 1090-1098
    • Yokoyama, M.1    Origasa, H.2    Matsuzaki, M.3
  • 4
    • 78549233384 scopus 로고    scopus 로고
    • N-3 fatty acids and cardiovascular events after myocardial infarction
    • Alpha Omega Trial Group
    • Kromhout D, Giltay EJ, Geleijnse JM; Alpha Omega Trial Group. n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med. 2010;363(21):2015-2026.
    • (2010) N Engl J Med , vol.363 , Issue.21 , pp. 2015-2026
    • Kromhout, D.1    Giltay, E.J.2    Geleijnse, J.M.3
  • 5
    • 84864219466 scopus 로고    scopus 로고
    • N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia
    • ORIGIN Trial Investigators
    • Bosch J, Gerstein HC, Dagenais GR, et al; ORIGIN Trial Investigators. n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med. 2012;367(4):309-318.
    • (2012) N Engl J Med , vol.367 , Issue.4 , pp. 309-318
    • Bosch, J.1    Gerstein, H.C.2    Dagenais, G.R.3
  • 6
    • 77956063072 scopus 로고    scopus 로고
    • Cardiovascular effects of marine omega-3 fatty acids
    • Saravanan P, Davidson NC, Schmidt EB, Calder PC. Cardiovascular effects of marine omega-3 fatty acids. Lancet. 2010;376(9740):540-550.
    • (2010) Lancet , vol.376 , Issue.9740 , pp. 540-550
    • Saravanan, P.1    Davidson, N.C.2    Schmidt, E.B.3    Calder, P.C.4
  • 7
    • 0037137299 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • American Heart Association Nutrition Committee
    • Kris-Etherton PM, Harris WS, Appel LJ; American Heart Association Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation. 2002;106(21):2747-2757.
    • (2002) Circulation , vol.106 , Issue.21 , pp. 2747-2757
    • Kris-Etherton, P.M.1    Harris, W.S.2    Appel, L.J.3
  • 8
    • 57349189353 scopus 로고    scopus 로고
    • Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology
    • ESC Committee for Practice Guidelines (CPG)
    • Van de Werf F, Bax J, Betriu A, et al; ESC Committee for Practice Guidelines (CPG). Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J. 2008;29(23):2909-2945.
    • (2008) Eur Heart J , vol.29 , Issue.23 , pp. 2909-2945
    • Van De Werf, F.1    Bax, J.2    Betriu, A.3
  • 9
    • 84873609399 scopus 로고    scopus 로고
    • Accessed August 20, 2012
    • US Food and Drug Administration. http://www.fda.gov. Accessed August 20, 2012.
  • 10
    • 84866489825 scopus 로고    scopus 로고
    • Accessed August 20, 2012
    • Electronic Medicines Compendium (eMC). http://www.medicines.org.uk/emc/ medicine/10312/indications. Accessed August 20, 2012.
    • Electronic Medicines Compendium (eMC)
  • 12
    • 67749093275 scopus 로고    scopus 로고
    • Omega-3 dietary supplements and the risk of cardiovascular events: A systematic review
    • Marik PE, Varon J. Omega-3 dietary supplements and the risk of cardiovascular events: a systematic review. Clin Cardiol. 2009;32(7):365-372.
    • (2009) Clin Cardiol , vol.32 , Issue.7 , pp. 365-372
    • Marik, P.E.1    Varon, J.2
  • 13
    • 67349092346 scopus 로고    scopus 로고
    • Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: A meta-analysis of randomized controlled trials
    • Zhao YT, Chen Q, Sun YX, et al. Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: a meta-analysis of randomized controlled trials. Ann Med. 2009;41(4):301-310.
    • (2009) Ann Med , vol.41 , Issue.4 , pp. 301-310
    • Zhao, Y.T.1    Chen, Q.2    Sun, Y.X.3
  • 14
    • 16644363207 scopus 로고    scopus 로고
    • Omega 3 fatty acids for prevention and treatment of cardiovascular disease
    • Hooper L, Thompson RL, Harrison RA, et al. Omega 3 fatty acids for prevention and treatment of cardiovascular disease. Cochrane Database Syst Rev. 2004;(4):CD003177.
    • (2004) Cochrane Database Syst Rev , Issue.4
    • Hooper, L.1    Thompson, R.L.2    Harrison, R.A.3
  • 16
    • 84861128254 scopus 로고    scopus 로고
    • Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: A meta-analysis of randomized, double-blind, placebo-controlled trials
    • Korean Meta-analysis Study Group. published online April 9, 2012. doi:10.1001/archinternmed.2012.262
    • Kwak SM, Myung SK, Lee YJ, Seo HG; Korean Meta-analysis Study Group. Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials [published online April 9, 2012]. Arch Intern Med. doi:10.1001/archinternmed.2012.262.
    • Arch Intern Med
    • Kwak, S.M.1    Myung, S.K.2    Lee, Y.J.3    Seo, H.G.4
  • 17
    • 84859001212 scopus 로고    scopus 로고
    • The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • Cochrane Bias Methods Group; Cochrane Statistical Methods Group
    • Higgins JP, Altman DG, Gøtzsche PC, et al; Cochrane Bias Methods Group; Cochrane Statistical Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
    • (2011) BMJ , vol.343
    • Higgins, J.P.1    Altman, D.G.2    Gøtzsche, P.C.3
  • 18
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539-1558.
    • (2002) Stat Med , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 19
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med. 1997;127(9):820-826.
    • (1997) Ann Intern Med , vol.127 , Issue.9 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 20
    • 0029957686 scopus 로고    scopus 로고
    • Large trials vs meta-analysis of smaller trials: How do their results compare?
    • Cappelleri JC, Ioannidis JP, Schmid CH, et al. Large trials vs meta-analysis of smaller trials: how do their results compare? JAMA. 1996;276(16):1332-1338.
    • (1996) JAMA , vol.276 , Issue.16 , pp. 1332-1338
    • Cappelleri, J.C.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 21
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50(4):1088-1101.
    • (1994) Biometrics , vol.50 , Issue.4 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 23
    • 84925548115 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009;62(10):1006-1012.
    • (2009) J Clin Epidemiol , vol.62 , Issue.10 , pp. 1006-1012
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 24
    • 0034967987 scopus 로고    scopus 로고
    • Effects of a high-dose concentrate of n-3 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol
    • Nilsen DW, Albrektsen G, Landmark K, Moen S, Aarsland T, Woie L. Effects of a high-dose concentrate of n-3 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol. Am J Clin Nutr. 2001;74(1):50-56.
    • (2001) Am J Clin Nutr , vol.74 , Issue.1 , pp. 50-56
    • Nilsen, D.W.1    Albrektsen, G.2    Landmark, K.3    Moen, S.4    Aarsland, T.5    Woie, L.6
  • 25
    • 0033528646 scopus 로고    scopus 로고
    • The effect of dietary omega-3 fatty acids on coronary atherosclerosis: A randomized, doubleblind, placebo-controlled trial
    • von Schacky C, Angerer P, Kothny W, Theisen K, Mudra H. The effect of dietary omega-3 fatty acids on coronary atherosclerosis: a randomized, doubleblind, placebo-controlled trial. Ann Intern Med. 1999;130(7):554-562.
    • (1999) Ann Intern Med , vol.130 , Issue.7 , pp. 554-562
    • Von Schacky, C.1    Angerer, P.2    Kothny, W.3    Theisen, K.4    Mudra, H.5
  • 26
    • 0032454852 scopus 로고    scopus 로고
    • Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease
    • Leng GC, Lee AJ, Fowkes FG, et al. Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease. Clin Nutr. 1998;17(6):265-271.
    • (1998) Clin Nutr , vol.17 , Issue.6 , pp. 265-271
    • Leng, G.C.1    Lee, A.J.2    Fowkes, F.G.3
  • 27
    • 0029015352 scopus 로고
    • Controlled trial of fish oil for regression of human coronary atherosclerosis
    • HARP Research Group
    • Sacks FM, Stone PH, Gibson CM, Silverman DI, Rosner B, Pasternak RC; HARP Research Group. Controlled trial of fish oil for regression of human coronary atherosclerosis. J Am Coll Cardiol. 1995;25(7):1492-1498.
    • (1995) J Am Coll Cardiol , vol.25 , Issue.7 , pp. 1492-1498
    • Sacks, F.M.1    Stone, P.H.2    Gibson, C.M.3    Silverman, D.I.4    Rosner, B.5    Pasternak, R.C.6
  • 28
    • 0030862755 scopus 로고    scopus 로고
    • Randomized, double-blind, placebocontrolled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: The Indian experiment of infarct survival 4
    • Singh RB, Niaz MA, Sharma JP, Kumar R, Rastogi V, Moshiri M. Randomized, double-blind, placebocontrolled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival 4. Cardiovasc Drugs Ther. 1997;11(3):485-491.
    • (1997) Cardiovasc Drugs Ther , vol.11 , Issue.3 , pp. 485-491
    • Singh, R.B.1    Niaz, M.A.2    Sharma, J.P.3    Kumar, R.4    Rastogi, V.5    Moshiri, M.6
  • 29
    • 79551499975 scopus 로고    scopus 로고
    • Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: A randomised placebo controlled trial
    • SU.FOL.OM3 Collaborative Group
    • Galan P, Kesse-Guyot E, Czernichow S, Briancon S, Blacher J, Hercberg S; SU.FOL.OM3 Collaborative Group. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ. 2010;341:c6273.
    • (2010) BMJ , vol.341
    • Galan, P.1    Kesse-Guyot, E.2    Czernichow, S.3    Briancon, S.4    Blacher, J.5    Hercberg, S.6
  • 30
    • 0037326841 scopus 로고    scopus 로고
    • Lack of benefit of dietary advice to men with angina: Results of a controlled trial
    • Burr ML, Ashfield-Watt PA, Dunstan FD, et al. Lack of benefit of dietary advice to men with angina: results of a controlled trial. Eur J Clin Nutr. 2003;57(2):193-200.
    • (2003) Eur J Clin Nutr , vol.57 , Issue.2 , pp. 193-200
    • Burr, M.L.1    Ashfield-Watt, P.A.2    Dunstan, F.D.3
  • 31
    • 0024363690 scopus 로고
    • Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial (DART)
    • Burr ML, Fehily AM, Gilbert JF, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet. 1989;2(8666):757-761.
    • (1989) Lancet , vol.2 , Issue.8666 , pp. 757-761
    • Burr, M.L.1    Fehily, A.M.2    Gilbert, J.F.3
  • 32
    • 34250640802 scopus 로고    scopus 로고
    • N-3 fatty acids as secondary prevention against cardiovascular events in patients who undergo chronic hemodialysis: A randomized, placebo-controlled intervention trial
    • OPACH Study Group
    • Svensson M, Schmidt EB, Jørgensen KA, Christensen JH; OPACH Study Group. N-3 fatty acids as secondary prevention against cardiovascular events in patients who undergo chronic hemodialysis: a randomized, placebo-controlled intervention trial. Clin J Am Soc Nephrol. 2006;1(4):780-786.
    • (2006) Clin J Am Soc Nephrol , vol.1 , Issue.4 , pp. 780-786
    • Svensson, M.1    Schmidt, E.B.2    Jørgensen, K.A.3    Christensen, J.H.4
  • 33
    • 20444461678 scopus 로고    scopus 로고
    • Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: A randomized controlled trial
    • Raitt MH, Connor WE, Morris C, et al. Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial. JAMA. 2005;293(23):2884-2891.
    • (2005) JAMA , vol.293 , Issue.23 , pp. 2884-2891
    • Raitt, M.H.1    Connor, W.E.2    Morris, C.3
  • 34
    • 27844607043 scopus 로고    scopus 로고
    • Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake
    • Fatty Acid Antiarrhythmia Trial Investigators
    • Leaf A, Albert CM, Josephson M, et al; Fatty Acid Antiarrhythmia Trial Investigators. Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake. Circulation. 2005;112(18):2762-2768.
    • (2005) Circulation , vol.112 , Issue.18 , pp. 2762-2768
    • Leaf, A.1    Albert, C.M.2    Josephson, M.3
  • 35
    • 33745100018 scopus 로고    scopus 로고
    • Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: The Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial
    • SOFA Study Group
    • Brouwer IA, Zock PL, Camm AJ, et al; SOFA Study Group. Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial. JAMA. 2006;295(22):2613-2619.
    • (2006) JAMA , vol.295 , Issue.22 , pp. 2613-2619
    • Brouwer, I.A.1    Zock, P.L.2    Camm, A.J.3
  • 36
    • 78650169331 scopus 로고    scopus 로고
    • OMEGA, a randomized, placebocontrolled trial to test the effect of highly purified omega-3 fatty acids on top of modern guidelineadjusted therapy after myocardial infarction
    • OMEGA Study Group
    • Rauch B, Schiele R, Schneider S, et al; OMEGA Study Group. OMEGA, a randomized, placebocontrolled trial to test the effect of highly purified omega-3 fatty acids on top of modern guidelineadjusted therapy after myocardial infarction. Circulation. 2010;122(21):2152-2159.
    • (2010) Circulation , vol.122 , Issue.21 , pp. 2152-2159
    • Rauch, B.1    Schiele, R.2    Schneider, S.3
  • 37
    • 77958588654 scopus 로고    scopus 로고
    • A randomized clinical trial on n-3 polyunsaturated fatty acids supplementation and all-cause mortality in elderly men at high cardiovascular risk
    • Einvik G, Klemsdal TO, Sandvik L, Hjerkinn EM. A randomized clinical trial on n-3 polyunsaturated fatty acids supplementation and all-cause mortality in elderly men at high cardiovascular risk. Eur J Cardiovasc Prev Rehabil. 2010;17(5):588-592.
    • (2010) Eur J Cardiovasc Prev Rehabil , vol.17 , Issue.5 , pp. 588-592
    • Einvik, G.1    Klemsdal, T.O.2    Sandvik, L.3    Hjerkinn, E.M.4
  • 38
    • 61649117933 scopus 로고    scopus 로고
    • Is antioxidant and n-3 supplementation able to improve functional status in poststroke patients? Results from the Nutristroke Trial
    • Garbagnati F, Cairella G, De Martino A, et al. Is antioxidant and n-3 supplementation able to improve functional status in poststroke patients? results from the Nutristroke Trial. Cerebrovasc Dis. 2009;27(4):375-383.
    • (2009) Cerebrovasc Dis , vol.27 , Issue.4 , pp. 375-383
    • Garbagnati, F.1    Cairella, G.2    De Martino, A.3
  • 39
    • 0036124659 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids in coronary heart disease: A meta-analysis of randomized controlled trials
    • Bucher HC, Hengstler P, Schindler C, Meier G. N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med. 2002;112(4):298-304.
    • (2002) Am J Med , vol.112 , Issue.4 , pp. 298-304
    • Bucher, H.C.1    Hengstler, P.2    Schindler, C.3    Meier, G.4
  • 40
    • 0027092441 scopus 로고
    • Role of triglycerides in coronary artery disease: Lessons from the Prospective Cardiovascular Münster Study
    • Assmann G, Schulte H. Role of triglycerides in coronary artery disease: lessons from the Prospective Cardiovascular Münster Study. Am J Cardiol. 1992;70(19):10H-13H.
    • (1992) Am J Cardiol , vol.70 , Issue.19
    • Assmann, G.1    Schulte, H.2
  • 41
    • 0026558610 scopus 로고
    • Lipids and risk of coronary heart disease: The Framingham Study
    • Castelli WP, Anderson K, Wilson PW, Levy D. Lipids and risk of coronary heart disease: the Framingham Study. Ann Epidemiol. 1992;2(1-2):23-28.
    • (1992) Ann Epidemiol , vol.2 , Issue.1-2 , pp. 23-28
    • Castelli, W.P.1    Anderson, K.2    Wilson, P.W.3    Levy, D.4
  • 42
    • 0038579421 scopus 로고    scopus 로고
    • Estimation of ten-year risk of fatal cardiovascular disease in Europe: The SCORE project
    • SCORE project group
    • Conroy RM, Pyörälä K, Fitzgerald AP, et al; SCORE project group. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J. 2003;24(11):987-1003.
    • (2003) Eur Heart J , vol.24 , Issue.11 , pp. 987-1003
    • Conroy, R.M.1    Pyörälä, K.2    Fitzgerald, A.P.3
  • 43
    • 27744574967 scopus 로고    scopus 로고
    • Epidemiology and stratification of risk for sudden cardiac death
    • Podrid PJ, Myerburg RJ. Epidemiology and stratification of risk for sudden cardiac death. Clin Cardiol. 2005;28(11)(suppl 1):I3-I11.
    • (2005) Clin Cardiol , vol.28 , Issue.11 SUPPL. 1
    • Podrid, P.J.1    Myerburg, R.J.2
  • 44
    • 0027284492 scopus 로고
    • Does fish oil lower blood pressure? A meta-analysis of controlled trials
    • Morris MC, Sacks F, Rosner B. Does fish oil lower blood pressure? a meta-analysis of controlled trials. Circulation. 1993;88(2):523-533.
    • (1993) Circulation , vol.88 , Issue.2 , pp. 523-533
    • Morris, M.C.1    Sacks, F.2    Rosner, B.3
  • 46
    • 67849129098 scopus 로고    scopus 로고
    • Omega- 3polyunsaturated fatty acids and cardiovascular diseases
    • Lavie CJ, Milani RV, Mehra MR, Ventura HO. Omega- 3polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol. 2009;54(7):585-594.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.7 , pp. 585-594
    • Lavie, C.J.1    Milani, R.V.2    Mehra, M.R.3    Ventura, H.O.4


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