-
1
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011; 17: 313-319.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
2
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008; 8: 755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
3
-
-
58149102321
-
Molecular basis of metastasis
-
Chiang AC, Massague J. Molecular basis of metastasis. N Engl J Med 2008; 359: 2814-2823.
-
(2008)
N Engl J Med
, vol.359
, pp. 2814-2823
-
-
Chiang, A.C.1
Massague, J.2
-
4
-
-
33751252276
-
Cancer Metastasis: Building a Framework
-
DOI 10.1016/j.cell.2006.11.001, PII S0092867406014140
-
Gupta GP, Massague J. Cancer metastasis: building a framework. Cell 2006; 127: 679-695. (Pubitemid 44781029)
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
5
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov 2009; 8: 579-591.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
6
-
-
45849089879
-
Exploring the role of cancer stem cells in radioresistance
-
DOI 10.1038/nrc2419, PII NRC2419
-
Baumann M, Krause M, Hill R. Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer 2008; 8: 545-554. (Pubitemid 351881850)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.7
, pp. 545-554
-
-
Baumann, M.1
Krause, M.2
Hill, R.3
-
7
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN et al. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 2009; 458: 780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
-
8
-
-
33845904383
-
The response of CD24(-/low)/CD44\+ breast cancer-initiating cells to radiation
-
Phillips TM, McBride WH, Pajonk F. The response of CD24(-/low)/CD44\+ breast cancer-initiating cells to radiation. J Natl Cancer Inst 2006; 98: 1777-1785.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1777-1785
-
-
Phillips, T.M.1
McBride, W.H.2
Pajonk, F.3
-
9
-
-
36148991764
-
Cancer stem cells in solid tumors
-
DOI 10.1016/j.copbio.2007.10.007, PII S0958166907001292, Expression Technologies / Tissue and Cell Engineering
-
Ailles LE, Weissman IL. Cancer stem cells in solid tumors. Curr Opin Biotechnol 2007; 18: 460-466. (Pubitemid 350116595)
-
(2007)
Current Opinion in Biotechnology
, vol.18
, Issue.5
, pp. 460-466
-
-
Ailles, L.E.1
Weissman, I.L.2
-
11
-
-
79953042645
-
CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule?
-
Zoller M. CD44: Can a cancer-initiating cell profit from an abundantly expressed molecule? Nat Rev Cancer 2011; 11: 254-267.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 254-267
-
-
Zoller, M.1
-
12
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100: 3983-3988. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
13
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
DOI 10.1158/0008-5472.CAN-05-2018
-
Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005; 65: 10946-10951. (Pubitemid 41713363)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
14
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
DOI 10.1073/pnas.0703478104
-
Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW et al. Phenotypic characterization of human colorectal cancer stem cells. Proc Natl Acad Sci USA 2007; 104: 10158-10163. (Pubitemid 47175279)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.-K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
15
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
DOI 10.1073/pnas.0610117104
-
Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, Dalerba P et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci USA 2007; 104: 973-978. (Pubitemid 46154721)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
16
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V et al. Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
-
17
-
-
0025282411
-
CD44 is the principal cell surface receptor for hyaluronate
-
Aruffo A, Stamenkovic I, Melnick M, Underhill CB, Seed B. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990; 61: 1303-1313.
-
(1990)
Cell
, vol.61
, pp. 1303-1313
-
-
Aruffo, A.1
Stamenkovic, I.2
Melnick, M.3
Underhill, C.B.4
Seed, B.5
-
18
-
-
11844256383
-
Mechanism and biological significance of CD44 cleavage
-
DOI 10.1111/j.1349-7006.2004.tb03179.x
-
Nagano O, Saya H. Mechanism and biological significance of CD44 cleavage. Cancer Sci 2004; 95: 930-935. (Pubitemid 40089583)
-
(2004)
Cancer Science
, vol.95
, Issue.12
, pp. 930-935
-
-
Nagano, O.1
Saya, H.2
-
20
-
-
61649087689
-
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
-
Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 2009; 33: 591-601.
-
(2009)
Mol Cell
, vol.33
, pp. 591-601
-
-
Warzecha, C.C.1
Sato, T.K.2
Nabet, B.3
Hogenesch, J.B.4
Carstens, R.P.5
-
21
-
-
0025825209
-
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
-
Gunthert U, Hofmann M, Rudy W, Reber S, Zoller M, Haussmann I et al. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991; 65: 13-24. (Pubitemid 121001209)
-
(1991)
Cell
, vol.65
, Issue.1
, pp. 13-24
-
-
Gunthert, U.1
Hofmann, M.2
Rudy, W.3
Reber, S.4
Zoller, M.5
Haussmann, I.6
Matzku, S.7
Wenzel, A.8
Ponta, H.9
Herrlich, P.10
-
22
-
-
0025248391
-
Retardation of metastatic tumor growth after immunization with metastasis-specific monoclonal antibodies
-
Reber S, Matzku S, Gunthert U, Ponta H, Herrlich P, Zoller M. Retardation of metastatic tumor growth after immunization with metastasis-specific monoclonal antibodies. Int J Cancer 1990; 46: 919-927.
-
(1990)
Int J Cancer
, vol.46
, pp. 919-927
-
-
Reber, S.1
Matzku, S.2
Gunthert, U.3
Ponta, H.4
Herrlich, P.5
Zoller, M.6
-
23
-
-
0027408671
-
Prevention of tumor metastasis formation by anti-variant CD44
-
Seiter S, Arch R, Reber S, Komitowski D, Hofmann M, Ponta H et al. Prevention of tumor metastasis formation by anti-variant CD44. J Exp Med 1993; 177: 443-455. (Pubitemid 23117094)
-
(1993)
Journal of Experimental Medicine
, vol.177
, Issue.2
, pp. 443-455
-
-
Seiter, S.1
Arch, R.2
Reber, S.3
Komitowski, D.4
Hofmann, M.5
Ponta, H.6
Herrlich, P.7
Matzku, S.8
Zoller, M.9
-
24
-
-
0027499085
-
Expression of CD44R1 adhesion molecule in colon carcinomas and metastases
-
DOI 10.1016/0140-6736(93)90490-8
-
Tanabe KK, Ellis LM, Saya H. Expression of CD44R1 adhesion molecule in colon carcinomas and metastases. Lancet 1993; 341: 725-726. (Pubitemid 23085181)
-
(1993)
Lancet
, vol.341
, Issue.8847
, pp. 725-726
-
-
Tanabe, K.K.1
Ellis, L.M.2
Saya, H.3
-
25
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
DOI 10.1038/nm1483, PII NM1483
-
Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 2006; 12: 1167-1174. (Pubitemid 44527352)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
26
-
-
80053101180
-
Neural stem cell niches: Roles for the hyaluronan-based extracellular matrix
-
Preston M, Sherman LS. Neural stem cell niches: roles for the hyaluronan-based extracellular matrix. Front Biosci 2011; 3: 1165-1179.
-
(2011)
Front Biosci
, vol.3
, pp. 1165-1179
-
-
Preston, M.1
Sherman, L.S.2
-
27
-
-
23244435467
-
How do stem cells find their way home?
-
DOI 10.1182/blood-2005-04-1417
-
Lapidot T, Dar A, Kollet O. How do stem cells find their way home? Blood 2005; 106: 1901-1910. (Pubitemid 41291700)
-
(2005)
Blood
, vol.106
, Issue.6
, pp. 1901-1910
-
-
Lapidot, T.1
Dar, A.2
Kollet, O.3
-
28
-
-
38949183635
-
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone
-
DOI 10.1038/nm1703, PII NM1703
-
Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP et al. Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nat Med 2008; 14: 181-187. (Pubitemid 351214550)
-
(2008)
Nature Medicine
, vol.14
, Issue.2
, pp. 181-187
-
-
Sackstein, R.1
Merzaban, J.S.2
Cain, D.W.3
Dagia, N.M.4
Spencer, J.A.5
Lin, C.P.6
Wohlgemuth, R.7
-
29
-
-
0030690228
-
Requirement for CD44 in activated T cell extravasation into an inflammatory site
-
DOI 10.1126/science.278.5338.672
-
DeGrendele HC, Estess P, Siegelman MH. Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science 1997; 278: 672-675. (Pubitemid 27464963)
-
(1997)
Science
, vol.278
, Issue.5338
, pp. 672-675
-
-
DeGrendele, H.C.1
Estess, P.2
Siegelman, M.H.3
-
30
-
-
79952528125
-
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
-
Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H et al. CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell 2011; 19: 387-400.
-
(2011)
Cancer Cell
, vol.19
, pp. 387-400
-
-
Ishimoto, T.1
Nagano, O.2
Yae, T.3
Tamada, M.4
Motohara, T.5
Oshima, H.6
-
32
-
-
33645167402
-
A novel antiapoptotic mechanism based on interference of Fas signaling by CD44 variant isoforms
-
Mielgo A, van Driel M, Bloem A, Landmann L, Gunthert U. A novel antiapoptotic mechanism based on interference of Fas signaling by CD44 variant isoforms. Cell Death Differ 2006; 13: 465-477.
-
(2006)
Cell Death Differ
, vol.13
, pp. 465-477
-
-
Mielgo, A.1
Van Driel, M.2
Bloem, A.3
Landmann, L.4
Gunthert, U.5
-
33
-
-
84855781227
-
Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
-
Bourguignon LY, Earle C, Wong G, Spevak CC, Krueger K. Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. Oncogene 2012; 31: 149-160.
-
(2012)
Oncogene
, vol.31
, pp. 149-160
-
-
Bourguignon, L.Y.1
Earle, C.2
Wong, G.3
Spevak, C.C.4
Krueger, K.5
-
34
-
-
46149112989
-
Hyaluronan CD44 and Emmprin: Partners in cancer cell chemoresistance
-
Toole BP, Slomiany MG. Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance. Drug Resist Update 2008; 11: 110-121.
-
(2008)
Drug Resist Update
, vol.11
, pp. 110-121
-
-
Toole, B.P.1
Slomiany, M.G.2
-
35
-
-
82755167828
-
Differentiation of breast cancer stem cells by knockdown of CD44: Promising differentiation therapy
-
Pham PV, Phan NL, Nguyen NT, Truong NH, Duong TT, Le DV et al. Differentiation of breast cancer stem cells by knockdown of CD44: promising differentiation therapy. J Transl Med 2011; 9: 209.
-
(2011)
J Transl Med
, vol.9
, pp. 209
-
-
Pham, P.V.1
Phan, N.L.2
Nguyen, N.T.3
Truong, N.H.4
Duong, T.T.5
Le, D.V.6
-
36
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011; 17: 211-215.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
Chen, X.4
Calhoun-Davis, T.5
Li, H.6
-
37
-
-
84867116299
-
Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance of colon cancer-initiating cells
-
Ohata H, Ishiguro T, Aihara Y, Sato A, Sakai H, Sekine S et al. Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance of colon cancer-initiating cells. Cancer Res 2012; 72: 5101-5110.
-
(2012)
Cancer Res
, vol.72
, pp. 5101-5110
-
-
Ohata, H.1
Ishiguro, T.2
Aihara, Y.3
Sato, A.4
Sakai, H.5
Sekine, S.6
-
38
-
-
58149269566
-
CD44 is of functional importance for colorectal cancer stem cells
-
Du L, Wang H, He L, Zhang J, Ni B, Wang X et al. CD44 is of functional importance for colorectal cancer stem cells. Clin Cancer Res 2008; 14: 6751-6760.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6751-6760
-
-
Du, L.1
Wang, H.2
He, L.3
Zhang, J.4
Ni, B.5
Wang, X.6
-
39
-
-
45549109525
-
Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/\+) mice attenuates intestinal tumorigenesis
-
Zeilstra J, Joosten SP, Dokter M, Verwiel E, Spaargaren M, Pals ST. Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/\+) mice attenuates intestinal tumorigenesis. Cancer Res 2008; 68: 3655-3661.
-
(2008)
Cancer Res
, vol.68
, pp. 3655-3661
-
-
Zeilstra, J.1
Joosten, S.P.2
Dokter, M.3
Verwiel, E.4
Spaargaren, M.5
Pals, S.T.6
-
40
-
-
23044437311
-
CD44 attenuates metastatic invasion during breast cancer progression
-
DOI 10.1158/0008-5472.CAN-05-0863
-
Lopez JI, Camenisch TD, Stevens MV, Sands BJ, McDonald J, Schroeder JA. CD44 attenuates metastatic invasion during breast cancer progression. Cancer Res 2005; 65: 6755-6763. (Pubitemid 41060713)
-
(2005)
Cancer Research
, vol.65
, Issue.15
, pp. 6755-6763
-
-
Lopez, J.I.1
Camenisch, T.D.2
Stevens, M.V.3
Sands, B.J.4
McDonald, J.5
Schroeder, J.A.6
-
41
-
-
33746504571
-
Invasive growth: A MET-driven genetic programme for cancer and stem cells
-
DOI 10.1038/nrc1912, PII NRC1912
-
Boccaccio C, Comoglio PM. Invasive growth: a MET-driven genetic programme for cancer and stem cells. Nat Rev Cancer 2006; 6: 637-645. (Pubitemid 44140861)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.8
, pp. 637-645
-
-
Boccaccio, C.1
Comoglio, P.M.2
-
42
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
DOI 10.1172/JCI200320530
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-1784. (Pubitemid 38063698)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
43
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
44
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119: 1420-1428.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
45
-
-
79952227361
-
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
-
Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J et al. CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest 2011; 121: 1064-1074.
-
(2011)
J Clin Invest
, vol.121
, pp. 1064-1074
-
-
Brown, R.L.1
Reinke, L.M.2
Damerow, M.S.3
Perez, D.4
Chodosh, L.A.5
Yang, J.6
-
46
-
-
80052322960
-
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype
-
Shapiro IM, Cheng AW, Flytzanis NC, Balsamo M, Condeelis JS, Oktay MH et al. An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. PLoS Genet 2011; 7: e1002218.
-
(2011)
PLoS Genet
, vol.7
-
-
Shapiro, I.M.1
Cheng, A.W.2
Flytzanis, N.C.3
Balsamo, M.4
Condeelis, J.S.5
Oktay, M.H.6
-
47
-
-
77957767273
-
An ESRPregulated splicing programme is abrogated during the epithelial-mesenchymal transition
-
Warzecha CC, Jiang P, Amirikian K, Dittmar KA, Lu H, Shen S et al. An ESRPregulated splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J 2010; 29: 3286-3300.
-
(2010)
EMBO J
, vol.29
, pp. 3286-3300
-
-
Warzecha, C.C.1
Jiang, P.2
Amirikian, K.3
Dittmar, K.A.4
Lu, H.5
Shen, S.6
-
48
-
-
84863603551
-
CD44s regulates the TGF-b-mediated mesenchymal phenotype and is associated with poor prognosis in patients with hepatocellular carcinoma
-
Mima K, Okabe H, Ishimoto T, Hayashi H, Nakagawa S, Kuroki H et al. CD44s regulates the TGF-b-mediated mesenchymal phenotype and is associated with poor prognosis in patients with hepatocellular carcinoma. Cancer Res 2012; 72: 3414-3423.
-
(2012)
Cancer Res
, vol.72
, pp. 3414-3423
-
-
Mima, K.1
Okabe, H.2
Ishimoto, T.3
Hayashi, H.4
Nakagawa, S.5
Kuroki, H.6
-
49
-
-
77950501023
-
Tumor necrosis factor-a regulates transforming growth factor-b-dependent epithelialmesenchymal transition by promoting hyaluronan-CD44-moesin interaction
-
Takahashi E, Nagano O, Ishimoto T, Yae T, Suzuki Y, Shinoda T et al. Tumor necrosis factor-a regulates transforming growth factor-b-dependent epithelialmesenchymal transition by promoting hyaluronan-CD44-moesin interaction. J Biol Chem 2010; 285: 4060-4073.
-
(2010)
J Biol Chem
, vol.285
, pp. 4060-4073
-
-
Takahashi, E.1
Nagano, O.2
Ishimoto, T.3
Yae, T.4
Suzuki, Y.5
Shinoda, T.6
-
50
-
-
0028958470
-
Regulation of growth and dissemination of a human lymphoma by CD44 splice variants
-
Bartolazzi A, Jackson D, Bennett K, Aruffo A, Dickinson R, Shields J et al. Regulation of growth and dissemination of a human lymphoma by CD44 splice variants. J Cell Sci 1995; 108: 1723-1733.
-
(1995)
J Cell Sci
, vol.108
, pp. 1723-1733
-
-
Bartolazzi, A.1
Jackson, D.2
Bennett, K.3
Aruffo, A.4
Dickinson, R.5
Shields, J.6
-
51
-
-
0029583425
-
Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons
-
DOI 10.1083/jcb.131.6.1623
-
Bennett KL, Modrell B, Greenfield B, Bartolazzi A, Stamenkovic I, Peach R et al. Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons. J Cell Biol 1995; 131: 1623-1633. (Pubitemid 26001764)
-
(1995)
Journal of Cell Biology
, vol.131
, Issue.I6
, pp. 1623-1633
-
-
Bennett, K.L.1
Modrell, B.2
Greenfield, B.3
Bartolazzi, A.4
Stamenkovic, I.5
Peach, R.6
Jackson, D.G.7
Spring, F.8
Aruffo, A.9
-
52
-
-
84863321158
-
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
-
Yae T, Tsuchihashi K, Ishimoto T, Motohara T, Yoshikawa M, Yoshida GJ et al. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun 2012; 3: 883.
-
(2012)
Nat Commun
, vol.3
, pp. 883
-
-
Yae, T.1
Tsuchihashi, K.2
Ishimoto, T.3
Motohara, T.4
Yoshikawa, M.5
Yoshida, G.J.6
-
53
-
-
40249113328
-
Direct regulation of TWIST by HIF-1a promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ et al. Direct regulation of TWIST by HIF-1a promotes metastasis. Nat Cell Biol 2008; 10: 295-305.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Liu, C.J.6
-
54
-
-
84855912001
-
Pericyte depletion results in hypoxia-associated epithelial-to- mesenchymal transition and metastasis mediated by Met signaling pathway
-
Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y et al. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by Met signaling pathway. Cancer Cell 2012; 21: 66-81.
-
(2012)
Cancer Cell
, vol.21
, pp. 66-81
-
-
Cooke, V.G.1
Lebleu, V.S.2
Keskin, D.3
Khan, Z.4
O'Connell, J.T.5
Teng, Y.6
-
55
-
-
67349114001
-
Hypoxia-inducible factor-1a induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition
-
Sun S, Ning X, Zhang Y, Lu Y, Nie Y, Han S et al. Hypoxia-inducible factor-1a induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition. Kidney Int 2009; 75: 1278-1287.
-
(2009)
Kidney Int
, vol.75
, pp. 1278-1287
-
-
Sun, S.1
Ning, X.2
Zhang, Y.3
Lu, Y.4
Nie, Y.5
Han, S.6
-
56
-
-
84865507272
-
Hypoxia regulates CD44 and its variant isoforms through HIF-1a in triple negative breast cancer
-
Krishnamachary B, Penet MF, Nimmagadda S, Mironchik Y, Raman V, Solaiyappan M et al. Hypoxia regulates CD44 and its variant isoforms through HIF-1a in triple negative breast cancer. PLoS One 2012; 7: e44078.
-
(2012)
PLoS One
, vol.7
-
-
Krishnamachary, B.1
Penet, M.F.2
Nimmagadda, S.3
Mironchik, Y.4
Raman, V.5
Solaiyappan, M.6
-
57
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
DOI 10.1016/j.ccr.2006.10.008, PII S153561080600314X
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527. (Pubitemid 44854747)
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.-P.9
Tong, F.10
Speed, T.11
Spellman, P.T.12
DeVries, S.13
Lapuk, A.14
Wang, N.J.15
Kuo, W.-L.16
Stilwell, J.L.17
Pinkel, D.18
Albertson, D.G.19
Waldman, F.M.20
McCormick, F.21
Dickson, R.B.22
Johnson, M.D.23
Lippman, M.24
Ethier, S.25
Gazdar, A.26
Gray, J.W.27
more..
-
58
-
-
77949577301
-
Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumor markers
-
Kannagi R, Sakuma K, Miyazaki K, Lim KT, Yusa A, Yin J et al. Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: clues in the ongoing search for new tumor markers. Cancer Sci 2010; 101: 586-593.
-
(2010)
Cancer Sci
, vol.101
, pp. 586-593
-
-
Kannagi, R.1
Sakuma, K.2
Miyazaki, K.3
Lim, K.T.4
Yusa, A.5
Yin, J.6
-
59
-
-
21344446792
-
CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity
-
DOI 10.1158/0008-5472.CAN-04-4557
-
Hanley WD, Burdick MM, Konstantopoulos K, Sackstein R. CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. Cancer Res 2005; 65: 5812-5817. (Pubitemid 40911185)
-
(2005)
Cancer Research
, vol.65
, Issue.13
, pp. 5812-5817
-
-
Hanley, W.D.1
Burdick, M.M.2
Konstantopoulos, K.3
Sackstein, R.4
-
60
-
-
0028985177
-
CD44 isoforms containing exon V3 are responsible for the presentation of heparinbinding growth factor
-
Bennett KL, Jackson DG, Simon JC, Tanczos E, Peach R, Modrell B et al. CD44 isoforms containing exon V3 are responsible for the presentation of heparinbinding growth factor. J Cell Biol 1995; 128: 687-698.
-
(1995)
J Cell Biol
, vol.128
, pp. 687-698
-
-
Bennett, K.L.1
Jackson, D.G.2
Simon, J.C.3
Tanczos, E.4
Peach, R.5
Modrell, B.6
-
61
-
-
0036468005
-
CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling
-
DOI 10.1101/gad.925702
-
Yu WH, Woessner Jr JF, McNeish JD, Stamenkovic I. CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling. Genes Dev 2002; 16: 307-323. (Pubitemid 34111411)
-
(2002)
Genes and Development
, vol.16
, Issue.3
, pp. 307-323
-
-
Yu, W.-H.1
Woessner Jr., F.2
McNeish, J.D.3
Stamenkovic, I.4
-
62
-
-
0036896923
-
CD44 is required for two consecutive steps in HGF/c-Met signaling
-
DOI 10.1101/gad.242602
-
Orian-Rousseau V, Chen L, Sleeman JP, Herrlich P, Ponta H. CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes Dev 2002; 16: 3074-3086. (Pubitemid 35424194)
-
(2002)
Genes and Development
, vol.16
, Issue.23
, pp. 3074-3086
-
-
Orian-Rousseau, V.1
Chen, L.2
Sleeman, J.P.3
Herrlich, P.4
Ponta, H.5
-
63
-
-
60549091044
-
Hyaluronan CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells
-
Slomiany MG, Grass GD, Robertson AD, Yang XY, Maria BL, Beeson C et al. Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res 2009; 69: 1293-1301.
-
(2009)
Cancer Res
, vol.69
, pp. 1293-1301
-
-
Slomiany, M.G.1
Grass, G.D.2
Robertson, A.D.3
Yang, X.Y.4
Maria, B.L.5
Beeson, C.6
-
64
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 2006; 12: 446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
-
65
-
-
34547660196
-
FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
-
DOI 10.1016/j.stem.2007.07.017, PII S1934590907000835
-
Tothova Z, Gilliland DG. FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system. Cell Stem Cell 2007; 1: 140-152. (Pubitemid 47215597)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.2
, pp. 140-152
-
-
Tothova, Z.1
Gilliland, D.G.2
-
66
-
-
70349446465
-
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
-
Owusu-Ansah E, Banerjee U. Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation. Nature 2009; 461: 537-541.
-
(2009)
Nature
, vol.461
, pp. 537-541
-
-
Owusu-Ansah, E.1
Banerjee, U.2
-
67
-
-
52549128786
-
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system
-
Macleod KF. The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system. Nat Rev Cancer 2008; 8: 769-781.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 769-781
-
-
MacLeod, K.F.1
-
68
-
-
33750510904
-
INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
-
DOI 10.1038/ncb1491, PII NCB1491
-
Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, Nakayama K et al. Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol 2006; 8: 1291-1297. (Pubitemid 44660595)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.11
, pp. 1291-1297
-
-
Takahashi, A.1
Ohtani, N.2
Yamakoshi, K.3
Iida, S.-I.4
Tahara, H.5
Nakayama, K.6
Nakayama, K.I.7
Ide, T.8
Saya, H.9
Hara, E.10
-
69
-
-
33748333105
-
The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation
-
DOI 10.1091/mbc.E05-06-0532
-
Li J, Stouffs M, Serrander L, Banfi B, Bettiol E, Charnay Y et al. The NADPH oxidase NOX4 drives cardiac differentiation: role in regulating cardiac transcription factors and MAP kinase activation. Mol Biol Cell 2006; 17: 3978-3988. (Pubitemid 44330881)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.9
, pp. 3978-3988
-
-
Li, J.1
Stouffs, M.2
Serrander, L.3
Banfi, B.4
Bettiol, E.5
Charnay, Y.6
Steger, K.7
Krause, K.-H.8
Jaconi, M.E.9
-
70
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
DOI 10.1016/j.cell.2007.04.019, PII S0092867407005259
-
Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007; 129: 465-472. (Pubitemid 46660978)
-
(2007)
Cell
, vol.129
, Issue.3
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
72
-
-
33751072935
-
Bioenergetics and the formation of mitochondrial reactive oxygen species
-
DOI 10.1016/j.tips.2006.10.005, PII S0165614706002495
-
Adam-Vizi V, Chinopoulos C. Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 2006; 27: 639-645. (Pubitemid 44767940)
-
(2006)
Trends in Pharmacological Sciences
, vol.27
, Issue.12
, pp. 639-645
-
-
Adam-Vizi, V.1
Chinopoulos, C.2
-
73
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
DOI 10.1016/j.cell.2005.02.001
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 2005; 120: 483-495. (Pubitemid 40269763)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
74
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956; 123: 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
75
-
-
79960060305
-
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
-
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature 2011; 475: 106-109.
-
(2011)
Nature
, vol.475
, pp. 106-109
-
-
Denicola, G.M.1
Karreth, F.A.2
Humpton, T.J.3
Gopinathan, A.4
Wei, C.5
Frese, K.6
-
76
-
-
33846811520
-
P38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis
-
DOI 10.1016/j.ccr.2006.12.013, PII S1535610806003801
-
Dolado I, Swat A, Ajenjo N, De Vita G, Cuadrado A, Nebreda AR. p38a MAP kinase as a sensor of reactive oxygen species in tumorigenesis. Cancer Cell 2007; 11: 191-205. (Pubitemid 46209847)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 191-205
-
-
Dolado, I.1
Swat, A.2
Ajenjo, N.3
De Vita, G.4
Cuadrado, A.5
Nebreda, A.R.6
-
78
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
DOI 10.1152/physrev.00044.2005
-
Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007; 87: 245-313. (Pubitemid 46209993)
-
(2007)
Physiological Reviews
, vol.87
, Issue.1
, pp. 245-313
-
-
Bedard, K.1
Krause, K.-H.2
-
79
-
-
79953328298
-
Tumor-associated neutrophils: New targets for cancer therapy
-
Gregory AD, Houghton AM. Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res 2011; 71: 2411-2416.
-
(2011)
Cancer Res
, vol.71
, pp. 2411-2416
-
-
Gregory, A.D.1
Houghton, A.M.2
-
80
-
-
3042736846
-
Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology
-
DOI 10.1023/B:CANC.0000031769.14728.bc
-
Spitz DR, Azzam EI, Li JJ, Gius D. Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology. Cancer Metast Rev 2004; 23: 311-322. (Pubitemid 38881814)
-
(2004)
Cancer and Metastasis Reviews
, vol.23
, Issue.3-4
, pp. 311-322
-
-
Spitz, D.R.1
Azzam, E.I.2
Li, J.J.3
Gius, D.4
-
81
-
-
84874418442
-
The convergence of radiation and immunogenic cell death signaling pathways
-
Golden EB, Pellicciotta I, Demaria S, Barcellos-Hoff MH, Formenti SC. The convergence of radiation and immunogenic cell death signaling pathways. Front Oncol 2012; 2: 88.
-
(2012)
Front Oncol
, vol.2
, pp. 88
-
-
Golden, E.B.1
Pellicciotta, I.2
Demaria, S.3
Barcellos-Hoff, M.H.4
Formenti, S.C.5
-
82
-
-
0030875480
-
Apoptosis and mitotic cell death: Their relative contributions to normal-tissue and tumour radiation response
-
DOI 10.1080/095530097143716
-
Hendry JH, West CM. Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response. Int J Radiat Biol 1997; 71: 709-719. (Pubitemid 27306026)
-
(1997)
International Journal of Radiation Biology
, vol.71
, Issue.6
, pp. 709-719
-
-
Hendry, J.H.1
West, G.M.L.2
-
83
-
-
9244261938
-
Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness
-
DOI 10.1177/1534735404270335
-
Conklin KA. Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness. Integr Cancer Ther 2004; 3: 294-300. (Pubitemid 39552423)
-
(2004)
Integrative Cancer Therapies
, vol.3
, Issue.4
, pp. 294-300
-
-
Conklin, K.A.1
-
84
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T et al. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 1999; 274: 7936-7940.
-
(1999)
J Biol Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
-
85
-
-
0021127473
-
Glutathione metabolism as a determinant of therapeutic efficacy: A review
-
Arrick BA, Nathan CF. Glutathione metabolism as a determinant of therapeutic efficacy: a review. Cancer Res 1984; 44: 4224-4232. (Pubitemid 14008726)
-
(1984)
Cancer Research
, vol.44
, Issue.10
, pp. 4224-4232
-
-
Arrick, B.A.1
Nathan, C.F.2
-
86
-
-
5344280431
-
Genetically altered mice to evaluate glutathione homeostasis in health and disease
-
DOI 10.1016/j.freeradbiomed.2004.06.040, PII S0891584904005349
-
Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG. Genetically altered mice to evaluate glutathione homeostasis in health and disease. Free Radic Biol Med 2004; 37: 1511-1526. (Pubitemid 39349798)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.10
, pp. 1511-1526
-
-
Dalton, T.P.1
Chen, Y.2
Schneider, S.N.3
Nebert, D.W.4
Shertzer, H.G.5
-
87
-
-
0024264526
-
Glutathione metabolism and its selective modification
-
Meister A. Glutathione metabolism and its selective modification. J Biol Chem 1988; 263: 17205-17208. (Pubitemid 19029311)
-
(1988)
Journal of Biological Chemistry
, vol.263
, Issue.33
, pp. 17205-17208
-
-
Meister, A.1
-
88
-
-
0029954846
-
Glutathione and related enzymes in multidrug resistance
-
O'Brien ML, Tew KD. Glutathione and related enzymes in multidrug resistance. Eur J Cancer 1996; 32A: 967-978.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 967-978
-
-
O'Brien, M.L.1
Tew, K.D.2
-
89
-
-
0028106016
-
Glutathione-associated enzymes in anticancer drug resistance
-
Tew KD. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res 1994; 54: 4313-4320. (Pubitemid 24273141)
-
(1994)
Cancer Research
, vol.54
, Issue.16
, pp. 4313-4320
-
-
Tew, K.D.1
-
90
-
-
79960427057
-
Selective killing of cancer cells by a small molecule targeting the stress response to ROS
-
Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 2011; 475: 231-234.
-
(2011)
Nature
, vol.475
, pp. 231-234
-
-
Raj, L.1
Ide, T.2
Gurkar, A.U.3
Foley, M.4
Schenone, M.5
Li, X.6
-
91
-
-
33748146888
-
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
-
DOI 10.1016/j.ccr.2006.08.009, PII S1535610806002509
-
Trachootham D, Zhou Y, Zhang H, Demizu Y, Chen Z, Pelicano H et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by b-phenylethyl isothiocyanate. Cancer Cell 2006; 10: 241-252. (Pubitemid 44311067)
-
(2006)
Cancer Cell
, vol.10
, Issue.3
, pp. 241-252
-
-
Trachootham, D.1
Zhou, Y.2
Zhang, H.3
Demizu, Y.4
Chen, Z.5
Pelicano, H.6
Chiao, P.J.7
Achanta, G.8
Arlinghaus, R.B.9
Liu, J.10
Huang, P.11
-
92
-
-
23844486685
-
Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance
-
DOI 10.1158/0008-5472.CAN-04-4267
-
Huang Y, Dai Z, Barbacioru C, Sadee W. Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. Cancer Res 2005; 65: 7446-7454. (Pubitemid 41161279)
-
(2005)
Cancer Research
, vol.65
, Issue.16
, pp. 7446-7454
-
-
Huang, Y.1
Dai, Z.2
Barbacioru, C.3
Sadee, W.4
-
93
-
-
42949126711
-
- cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases
-
DOI 10.1002/jcp.21366
-
Lo M, Wang YZ, Gout PW. The x(c)-cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases. J Cell Physiol 2008; 215: 593-602. (Pubitemid 351632680)
-
(2008)
Journal of Cellular Physiology
, vol.215
, Issue.3
, pp. 593-602
-
-
Lo, M.1
Wang, Y.-Z.2
Gout, P.W.3
-
94
-
-
27844530663
-
Redox imbalance in cystine/glutamate transporter-deficient mice
-
DOI 10.1074/jbc.M506439200
-
Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y et al. Redox imbalance in cystine/glutamate transporter-deficient mice. J Biol Chem 2005; 280: 37423-37429. (Pubitemid 41642349)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.45
, pp. 37423-37429
-
-
Sato, H.1
Shiiya, A.2
Kimata, M.3
Maebara, K.4
Tamba, M.5
Sakakura, Y.6
Makino, N.7
Sugiyama, F.8
Yagami, K.-I.9
Moriguchi, T.10
Takahashi, S.11
Bannai, S.12
-
95
-
-
0023513624
-
Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine
-
DOI 10.1002/jcp.1041330217
-
Ishii T, Sugita Y, Bannai S. Regulation of glutathione levels in mouse spleen lymphocytes by transport of cysteine. J Cell Physiol 1987; 133: 330-336. (Pubitemid 18000329)
-
(1987)
Journal of Cellular Physiology
, vol.133
, Issue.2
, pp. 330-336
-
-
Ishi, T.1
Sugita, Y.2
Bannai, S.3
-
96
-
-
0037160092
-
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
-
DOI 10.1074/jbc.M208704200
-
Sasaki H, Sato H, Kuriyama-Matsumura K, Sato K, Maebara K, Wang H et al. Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J Biol Chem 2002; 277: 44765-44771. (Pubitemid 36159069)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 44765-44771
-
-
Sasaki, H.1
Sato, H.2
Kuriyama-Matsumura, K.3
Sato, K.4
Maebara, K.5
Wang, H.6
Tamba, M.7
Itoh, K.8
Yamamoto, M.9
Bannai, S.10
-
97
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
DOI 10.1016/S1097-2765(03)00105-9
-
Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 2003; 11: 619-633. (Pubitemid 36385118)
-
(2003)
Molecular Cell
, vol.11
, Issue.3
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
98
-
-
84859582963
-
Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression
-
Lewerenz J, Sato H, Albrecht P, Henke N, Noack R, Methner A et al. Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression. Cell Death Differ 2012; 19: 847-858.
-
(2012)
Cell Death Differ
, vol.19
, pp. 847-858
-
-
Lewerenz, J.1
Sato, H.2
Albrecht, P.3
Henke, N.4
Noack, R.5
Methner, A.6
-
99
-
-
59449086812
-
Basal levels of eIF2a phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression
-
Lewerenz J, Maher P. Basal levels of eIF2a phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression. J Biol Chem 2009; 284: 1106-1115.
-
(2009)
J Biol Chem
, vol.284
, pp. 1106-1115
-
-
Lewerenz, J.1
Maher, P.2
-
100
-
-
0038239858
-
-, by xCT and rBAT
-
DOI 10.1016/S0006-291X(03)00808-8
-
Wang H, Tamba M, Kimata M, Sakamoto K, Bannai S, Sato H. Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT. Biochem Biophys Res Commun 2003; 305: 611-618. (Pubitemid 36579275)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.305
, Issue.3
, pp. 611-618
-
-
Wang, H.1
Tamba, M.2
Kimata, M.3
Sakamoto, K.4
Bannai, S.5
Sato, H.6
-
101
-
-
1342281232
-
CATs and HATs: The SLC7 family of amino acid transporters
-
DOI 10.1007/s00424-003-1086-z, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
-
Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y. CATs and HATs: the SLC7 family of amino acid transporters. Pflugers Arch 2004; 447: 532-542. (Pubitemid 38258215)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.447
, Issue.5
, pp. 532-542
-
-
Verrey, F.1
Closs, E.I.2
Wagner, C.A.3
Palacin, M.4
Endou, H.5
Kanai, Y.6
-
102
-
-
84866926512
-
Exploratory clinical trial of (4S)-4-(3-[18F]fluoropropyl)-L-glutamate for imaging xC-transporter using positron emission tomography in patients with non-small cell lung or breast cancer
-
Baek S, Choi CM, Ahn SH, Lee JW, Gong G, Ryu JS et al. Exploratory clinical trial of (4S)-4-(3-[18F]fluoropropyl)-L-glutamate for imaging xC-transporter using positron emission tomography in patients with non-small cell lung or breast cancer. Clin Cancer Res 2012; 18: 5427-5437.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5427-5437
-
-
Baek, S.1
Choi, C.M.2
Ahn, S.H.3
Lee, J.W.4
Gong, G.5
Ryu, J.S.6
-
103
-
-
33750306612
-
Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
-
DOI 10.1158/1078-0432.CCR-06-0169
-
Balic M, Lin H, Young L, Hawes D, Giuliano A, McNamara G et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 2006; 12: 5615-5621. (Pubitemid 44629587)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.19
, pp. 5615-5621
-
-
Balic, M.1
Lin, H.2
Young, L.3
Hawes, D.4
Giuliano, A.5
McNamara, G.6
Datar, R.H.7
Cote, R.J.8
-
104
-
-
80053904142
-
Distinct types of tumor-initiating cells form human colon cancer tumors and metastases
-
Dieter SM, Ball CR, Hoffmann CM, Nowrouzi A, Herbst F, Zavidij O et al. Distinct types of tumor-initiating cells form human colon cancer tumors and metastases. Cell Stem Cell 2011; 9: 357-365.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 357-365
-
-
Dieter, S.M.1
Ball, C.R.2
Hoffmann, C.M.3
Nowrouzi, A.4
Herbst, F.5
Zavidij, O.6
-
105
-
-
34548455927
-
Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
-
DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007; 1: 313-323. (Pubitemid 47355323)
-
(2007)
Cell Stem Cell
, vol.1
, Issue.3
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
106
-
-
72949118673
-
High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability
-
Croker AK, Goodale D, Chu J, Postenka C, Hedley BD, Hess DA et al. High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. J Cell Mol Med 2009; 13: 2236-2252.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2236-2252
-
-
Croker, A.K.1
Goodale, D.2
Chu, J.3
Postenka, C.4
Hedley, B.D.5
Hess, D.A.6
-
107
-
-
78149262994
-
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
-
Liu H, Patel MR, Prescher JA, Patsialou A, Qian D, Lin J et al. Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci USA 2010; 107: 18115-18120.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18115-18120
-
-
Liu, H.1
Patel, M.R.2
Prescher, J.A.3
Patsialou, A.4
Qian, D.5
Lin, J.6
-
108
-
-
33645026803
-
Highly purified CD44\+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
-
Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, Tang S et al. Highly purified CD44\+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 2006; 25: 1696-1708.
-
(2006)
Oncogene
, vol.25
, pp. 1696-1708
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Li, H.4
Bhatia, B.5
Tang, S.6
-
109
-
-
44749091840
-
Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
-
Naor D, Wallach-Dayan SB, Zahalka MA, Sionov RV. Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 2008; 18: 260-267.
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 260-267
-
-
Naor, D.1
Wallach-Dayan, S.B.2
Zahalka, M.A.3
Sionov, R.V.4
-
110
-
-
0037089521
-
Absence of the CD44 gene prevents sarcoma metastasis
-
Weber GF, Bronson RT, Ilagan J, Cantor H, Schmits R, Mak TW. Absence of the CD44 gene prevents sarcoma metastasis. Cancer Res 2002; 62: 2281-2286. (Pubitemid 34411705)
-
(2002)
Cancer Research
, vol.62
, Issue.8
, pp. 2281-2286
-
-
Weber, G.F.1
Bronson, R.T.2
Ilagan, J.3
Cantor, H.4
Schmits, R.5
Mak, T.W.6
-
111
-
-
38849107424
-
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
-
DOI 10.1038/ncb1681, PII NCB1681
-
Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 2008; 10: 202-210. (Pubitemid 351194050)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.2
, pp. 202-210
-
-
Huang, Q.1
Gumireddy, K.2
Schrier, M.3
Le Sage, C.4
Nagel, R.5
Nair, S.6
Egan, D.A.7
Li, A.8
Huang, G.9
Klein-Szanto, A.J.10
Gimotty, P.A.11
Katsaros, D.12
Coukos, G.13
Zhang, L.14
Pure, E.15
Agami, R.16
-
112
-
-
78650961285
-
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-kB signaling
-
Qu Y, Wang J, Ray PS, Guo H, Huang J, Shin-Sim M et al. Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-kB signaling. J Clin Invest 2011; 121: 212-225.
-
(2011)
J Clin Invest
, vol.121
, pp. 212-225
-
-
Qu, Y.1
Wang, J.2
Ray, P.S.3
Guo, H.4
Huang, J.5
Shin-Sim, M.6
-
113
-
-
80052566377
-
Tumor entrained neutrophils inhibit seeding in the premetastatic lung
-
Granot Z, Henke E, Comen EA, King TA, Norton L, Benezra R. Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell 2011; 20: 300-314.
-
(2011)
Cancer Cell
, vol.20
, pp. 300-314
-
-
Granot, Z.1
Henke, E.2
Comen, E.A.3
King, T.A.4
Norton, L.5
Benezra, R.6
-
114
-
-
0031960284
-
Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature
-
DOI 10.1002/hep.510270510
-
Anasagasti MJ, Martin JJ, Mendoza L, Obrador E, Estrela JM, McCuskey RS et al. Glutathione protects metastatic melanoma cells against oxidative stress in the murine hepatic microvasculature. Hepatology 1998; 27: 1249-1256. (Pubitemid 28227851)
-
(1998)
Hepatology
, vol.27
, Issue.5
, pp. 1249-1256
-
-
Anasagasti, M.J.1
Martin, J.J.2
Mendoza, L.3
Obrador, E.4
Estrela, J.M.5
McCuskey, R.S.6
Vidal-Vanaclocha, F.7
-
115
-
-
0036140408
-
γ-glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver
-
DOI 10.1053/jhep.2002.30277
-
Obrador E, Carretero J, Ortega A, Medina I, Rodilla V, Pellicer JA et al. g-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver. Hepatology 2002; 35: 74-81. (Pubitemid 34032545)
-
(2002)
Hepatology
, vol.35
, Issue.1
, pp. 74-81
-
-
Obrador, E.1
Carretero, J.2
Ortega, A.3
Medina, I.4
Rodilla, V.5
Pellicer, J.A.6
Estrela, J.M.7
|