The response of CD24-/low/CD44+ breast cancer-initiating cells to radiation

Journal of the National Cancer Institute

Volumn 98, Issue 24, 2006, Pages 1777-1785

  Phillips, Tiffany M ^a   McBride, William H ^a   Pajonk, Frank ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD24 ANTIGEN; HERMES ANTIGEN; HISTONE H2AX; NOTCH1 RECEPTOR; REACTIVE OXYGEN METABOLITE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CARCINOGENESIS; CELL ADHESION; CELL COUNT; CELL GROWTH; CELL POPULATION; CELL STRAIN MCF 7; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RADIATION DOSE FRACTIONATION; RADIATION RESPONSE; RADIOSENSITIVITY; SHORT COURSE THERAPY; TREATMENT FAILURE;

ANTIGENS, CD24; ANTIGENS, CD44; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL SURVIVAL; DOSE FRACTIONATION; FEMALE; FLOW CYTOMETRY; HISTONES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; PHOSPHORYLATION; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; TUMOR STEM CELLS;

EID: 33845904383     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djj495     Document Type: Article

References (33)

1. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature 2004;432: 396-401.
2. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003;100:3983-8.
3. Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005;65:10946-51.
4. Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 2005;65:9328-37.
5. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001;414:105-11.
6. Lange CS, Gilbert CW. Studies on the cellular basis of radiation lethality. 3. The measurement of stem-cell repopulation probability. Int J Radiat Biol Relat Stud Phys Chem Med 1968;14:373-88.
7. Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, Coradini D, et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 2005;65:5506-11.
8. Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-71.
9. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003;63:5821-8.
10. Beachy PA, Karhadkar SS, Berman DM. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004;432:324-31.
11. Taipale J, Beachy PA. The Hedgehog and Wnt signalling pathways in cancer. Nature 2001;411:349-54.
12. Parr C, Watkins G, Jiang WG. The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer. Int J Mol Med 2004;14:779-86.
13. Chen Y, Fischer WH, Gill GN. Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH. J Biol Chem 1997;272:14110-4.
14. Ronchini C, Capobianco AJ. Induction of cyclin D1 transcription and CDK2 activity by Notch(ic): Implication for cell cycle disruption in transformation by Notch(ic). Mol Cell Biol 2001;21:5925-34.
15. Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med 2002;8:979-86.
16. Stackhouse MA, Buchsbaum DJ, Grizzle WE, Bright SJ, Olsen CC, Kancharla S, et al. Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo. Int J Radiat Oncol Biol Phys 1998;42:817-22.
17. Politi K, Feirt N, Kitajewski J. Notch in mammary gland development and breast cancer. Semin Cancer Biol 2004;14:341-7.
18. Dievart A, Beaulieu N, Jolicoeur P. Involvement of Notch1 in the development of mouse mammary tumors. Oncogene 1999;18:5973-81.
19. Withers HR, Reid BO, Hussey DH. Response of mouse jejunum to multifraction radiation. Int J Radiat Oncol Biol Phys 1975;1:41-52.
20. Steel GG, McMillan TJ, Peacock JH. The 5Rs of radiobiology. Int J Radiat Biol 1989;56:1045-8.
21. Withers HR, Maciejewski B, Taylor JM, Hliniak A. Accelerated repopulation in head and neck cancer. Front Radiat Ther Oncol 1988;22:105-10.
22. Kirkpatrick JP, Marks LB. Modeling killing and repopulation kinetics of subclinical cancer: Direct calculations from clinical data. Int J Radiat Oncol Biol Phys 2004;58:641-54.
23. Johnson A. The timing of treatment in breast cancer: Gaps and delays in treatment can be harmful. Breast Cancer Res Treat 2000;60:201-9.
24. Bese NS, Sut PA, Ober A. The effect of treatment interruptions in the post-operative irradiation of breast cancer. Oncology 2005;69:214-23.
25. Albright N. Computer programs for the analysis of cellular survival data. Radiat Res 1987;112:331-40.
26. Olive PL. Detection of DNA damage in individual cells by analysis of histone H2AX phosphorylation. Methods Cell Biol 2004;75:355-73.
27. Wollman R, Yahalom J, Maxy R, Pinto J, Fuks Z. Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro. Int J Radiat Oncol Biol Phys 1994;30:91-8.
28. Paris F, Fuks Z, Kang A, Capodieci P, Juan G, Ehleiter D, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001;293:293-7.
29. Dontu G, Jackson KW, McNicholas E, Kawamura MJ, Abdallah WM, Wicha MS. Role of Notch signaling in cell-fate determination of human mammary stem/ progenitor cells. Breast Cancer Res 2004;6:R605-15.
30. Holtz MS, Forman SJ, Bhatia R. Nonproliferating CML CD34+ progenitors are resistant to apoptosis induced by a wide range of proapoptotic stimuli. Leukemia 2005;19:1034-41.
31. West CM. Size-dependent resistance of human tumour spheroids to photodynamic treatment. Br J Cancer 1989;59:510-4.
32. Sutherland RM, Durand RE. Radiation response of multicell spheroids - an in vitro tumour model. Curr Top Radiat Res Q 1976;11:87-139.
33. Frankel A, Buckman R, Kerbel RS. Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids. Cancer Res 1997;57:2388-93.