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Volumn 23, Issue 3-4, 2004, Pages 311-322

Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology

Author keywords

aging; cancer; metabolism; mitochondria; non targeted effects; oxidative stress; redox regulation; signal transduction; superoxide dismutase; thioredoxin

Indexed keywords

FREE RADICAL; OXIDIZING AGENT; REDUCING AGENT; SUPEROXIDE DISMUTASE; THIOREDOXIN; TRANSCRIPTION FACTOR;

EID: 3042736846     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CANC.0000031769.14728.bc     Document Type: Review
Times cited : (584)

References (110)
  • 6
    • 0027207112 scopus 로고
    • Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation
    • Chiu SM, Xue LY, Friedman LR, Oleinick NL: Copper ion-mediated sensitization of nuclear matrix attachment sites to ionizing radiation. Biochemistry 32: 6214-6219, 1993
    • (1993) Biochemistry , vol.32 , pp. 6214-6219
    • Chiu, S.M.1    Xue, L.Y.2    Friedman, L.R.3    Oleinick, N.L.4
  • 7
    • 0017129965 scopus 로고
    • Protection of post-irradiated mice by superoxide dismutase
    • Petkau A, Chelack WS, Pleskach SD: Protection of post-irradiated mice by superoxide dismutase. Int J Radiat Biol 29: 297-299, 1976
    • (1976) Int J Radiat Biol , vol.29 , pp. 297-299
    • Petkau, A.1    Chelack, W.S.2    Pleskach, S.D.3
  • 9
    • 0020521199 scopus 로고
    • The role of thiols in cellular response to radiation and drugs
    • Biaglow JE, Varnes ME, Clark EP, Epp ER: The role of thiols in cellular response to radiation and drugs. Radiat Res 95: 437-455, 1983
    • (1983) Radiat Res , vol.95 , pp. 437-455
    • Biaglow, J.E.1    Varnes, M.E.2    Clark, E.P.3    Epp, E.R.4
  • 10
    • 0023270590 scopus 로고
    • The role of glutathione in radiation and drug induced cytotoxicity
    • Mitchell JB, Russo A: The role of glutathione in radiation and drug induced cytotoxicity. Br J Cancer 55: S96-S104, 1987
    • (1987) Br J Cancer , vol.55
    • Mitchell, J.B.1    Russo, A.2
  • 11
    • 0026598058 scopus 로고
    • Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity
    • Tuttle SW, Varnes ME, Mitchell JB, Biaglow JE: Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity. Int J Radiat Oncol Biol Phys 22: 671-675, 1992
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 671-675
    • Tuttle, S.W.1    Varnes, M.E.2    Mitchell, J.B.3    Biaglow, J.E.4
  • 12
    • 0027093827 scopus 로고
    • Suppression of radiation-induced neoplastic transformaton by overexpression of mitochondrial superoxide dismutase
    • St.Clair DK, Wan XS, Oberley TD, Muse KE, St.Clair WH: Suppression of radiation-induced neoplastic transformaton by overexpression of mitochondrial superoxide dismutase. Mol Carcinogenesis 6: 238-242, 1992
    • (1992) Mol Carcinogenesis , vol.6 , pp. 238-242
    • St.Clair, D.K.1    Wan, X.S.2    Oberley, T.D.3    Muse, K.E.4    St.Clair, W.H.5
  • 13
    • 0033809159 scopus 로고    scopus 로고
    • Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-plasmid/Liposome (SOD2-PL) intratracheal gene therapy
    • Epperly MW, Epstein CJ, Travis EL, Greenberger JS: Decreased pulmonary radiation resistance of manganese superoxide dismutase (MnSOD)-deficient mice is corrected by human manganese superoxide dismutase-plasmid/Liposome (SOD2-PL) intratracheal gene therapy. Radiat Res 154: 365-374, 2000
    • (2000) Radiat Res , vol.154 , pp. 365-374
    • Epperly, M.W.1    Epstein, C.J.2    Travis, E.L.3    Greenberger, J.S.4
  • 15
    • 0037155915 scopus 로고    scopus 로고
    • Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress
    • Ayene IS, Stamato TD, Mauldin SK, Biaglow JE, Tuttle SW, Jenkins SF, Koch CJ: Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress. J Biol Chem 277: 9929-9935, 2002
    • (2002) J Biol Chem , vol.277 , pp. 9929-9935
    • Ayene, I.S.1    Stamato, T.D.2    Mauldin, S.K.3    Biaglow, J.E.4    Tuttle, S.W.5    Jenkins, S.F.6    Koch, C.J.7
  • 16
    • 0023190840 scopus 로고
    • Increase in manganese superoxide dismutase activity in the mouse heart after X-irradiation
    • Oberley LW, St. Clair DK, Autor AP, Oberley TD: Increase in manganese superoxide dismutase activity in the mouse heart after X-irradiation. Arch Biochem Biophys 254: 69-80, 1987
    • (1987) Arch Biochem Biophys , vol.254 , pp. 69-80
    • Oberley, L.W.1    St. Clair, D.K.2    Autor, A.P.3    Oberley, T.D.4
  • 18
    • 0000144897 scopus 로고    scopus 로고
    • Enhancement of radiation-inducible hepatic glutathione-S-transferases Ya, Yb1, Yb2, Yc1, and Yc2 gene expression by oltipraz: Possible role in radioprotection
    • Kim SG, Nam SY, Kim CW, Kim JH, Cho CK, Yoo SY: Enhancement of radiation-inducible hepatic glutathione-S-transferases Ya, Yb1, Yb2, Yc1, and Yc2 gene expression by oltipraz: Possible role in radioprotection. Mol Pharmacol 51(2): 225-233, 1997
    • (1997) Mol Pharmacol , vol.51 , Issue.2 , pp. 225-233
    • Kim, S.G.1    Nam, S.Y.2    Kim, C.W.3    Kim, J.H.4    Cho, C.K.5    Yoo, S.Y.6
  • 21
    • 0018784261 scopus 로고
    • Keilin's respiratory chain concept and its chemiosmotic consequences
    • Mitchell P: Keilin's respiratory chain concept and its chemiosmotic consequences. Science 206: 1148-1159, 1979
    • (1979) Science , vol.206 , pp. 1148-1159
    • Mitchell, P.1
  • 29
    • 0024307578 scopus 로고
    • Oxygen toxicity and reactive oxygen metabolites in mammals
    • Jamieson D: Oxygen toxicity and reactive oxygen metabolites in mammals. Free Radic Biol Med 7: 87-108, 1989
    • (1989) Free Radic Biol Med , vol.7 , pp. 87-108
    • Jamieson, D.1
  • 30
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D: Aging: A theory based on free radical and radiation chemistry. J Gerontol 2: 298-300, 1957
    • (1957) J Gerontol , vol.2 , pp. 298-300
    • Harman, D.1
  • 31
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of aging
    • Finkel T, Holbrook NJ: Oxidants, oxidative stress and the biology of aging. Nature 408: 239-247, 2000
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 32
    • 0019455715 scopus 로고
    • Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide
    • Oberley LW, Oberley TD, Buettner GR: Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide. Med Hypotheses 7: 21-42, 1981
    • (1981) Med Hypotheses , vol.7 , pp. 21-42
    • Oberley, L.W.1    Oberley, T.D.2    Buettner, G.R.3
  • 33
    • 0034038708 scopus 로고    scopus 로고
    • Glucose deprivation-induced oxidative stress in human tumor cells: A fundamental defect in metabolism?
    • Spitz DR, Sim JE, Ridnour LA, Galoforo SS, Lee YJ: Glucose deprivation-induced oxidative stress in human tumor cells: A fundamental defect in metabolism? Ann NY Acad Sci 899: 349-362, 2000
    • (2000) Ann NY Acad Sci , vol.899 , pp. 349-362
    • Spitz, D.R.1    Sim, J.E.2    Ridnour, L.A.3    Galoforo, S.S.4    Lee, Y.J.5
  • 34
    • 0035371184 scopus 로고    scopus 로고
    • Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
    • Schafer FQ, Buettner GR: Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 30: 1191-1212, 2001
    • (2001) Free Radic Biol Med , vol.30 , pp. 1191-1212
    • Schafer, F.Q.1    Buettner, G.R.2
  • 35
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: Oxidants and antioxidants
    • Sies H: Oxidative stress: Oxidants and antioxidants. Exp Physiol 82: 291-295, 1997
    • (1997) Exp Physiol , vol.82 , pp. 291-295
    • Sies, H.1
  • 36
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of aging
    • Finkel T, Holbrook NJ: Oxidants, oxidative stress and the biology of aging. Nature 408(6809): 239-247, 2000
    • (2000) Nature , vol.408 , Issue.6809 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 37
    • 0034938799 scopus 로고    scopus 로고
    • Anticancer therapy by overexpression of superoxide dismutase
    • Oberley LW: Anticancer therapy by overexpression of superoxide dismutase. Antioxidants & Redox Signaling 3(3): 461-472, 2001
    • (2001) Antioxidants & Redox Signaling , vol.3 , Issue.3 , pp. 461-472
    • Oberley, L.W.1
  • 41
    • 0038006958 scopus 로고    scopus 로고
    • Antioxidant vitamins E and C and risk of Alzheimer's disease
    • Martin A: Antioxidant vitamins E and C and risk of Alzheimer's disease. Nutrition Reviews 61(2): 69-73, 2003
    • (2003) Nutrition Reviews , vol.61 , Issue.2 , pp. 69-73
    • Martin, A.1
  • 42
    • 0041808751 scopus 로고    scopus 로고
    • An argument for Vitamin E supplementation in the management of systemic inflammatory response syndrome
    • Bulger EM, Maier RV: An argument for Vitamin E supplementation in the management of systemic inflammatory response syndrome. Shock 19(2): 99-103, 2003
    • (2003) Shock , vol.19 , Issue.2 , pp. 99-103
    • Bulger, E.M.1    Maier, R.V.2
  • 46
    • 0034792157 scopus 로고    scopus 로고
    • Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation
    • Claiborne A, Mallett TC, Yeh JI, Luba J, Parsonage D: Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation. Adv Protein Chem 58: 215-276, 2001
    • (2001) Adv Protein Chem , vol.58 , pp. 215-276
    • Claiborne, A.1    Mallett, T.C.2    Yeh, J.I.3    Luba, J.4    Parsonage, D.5
  • 47
    • 0033598677 scopus 로고    scopus 로고
    • Protein-sulfenic acids: Diverse roles for an unlikely player in enzyme catalysis and redox regulation
    • Claiborne A, Yeh JI, Mallett TC, Luba J, Crane EJ, Charrier V, Parsonage D: Protein-sulfenic acids: Diverse roles for an unlikely player in enzyme catalysis and redox regulation. Biochemistry 38(47): 15407-15416, 1999
    • (1999) Biochemistry , vol.38 , Issue.47 , pp. 15407-15416
    • Claiborne, A.1    Yeh, J.I.2    Mallett, T.C.3    Luba, J.4    Crane, E.J.5    Charrier, V.6    Parsonage, D.7
  • 49
    • 0029760957 scopus 로고    scopus 로고
    • Redox regulation of transcriptional activators
    • Sun Yi, Oberley LW: Redox regulation of transcriptional activators. Free Radic Biol Med 21: 335-348, 1996
    • (1996) Free Radic Biol Med , vol.21 , pp. 335-348
    • Sun, Y.1    Oberley, L.W.2
  • 50
    • 0032570704 scopus 로고    scopus 로고
    • Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells
    • Lee YJ, Galoforo SS, Berns CM, Chen JC, Davis BH, Sim JE, Corry PM, Spitz DR: Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells. J Biol Chem 273: 5294-5299, 1998
    • (1998) J Biol Chem , vol.273 , pp. 5294-5299
    • Lee, Y.J.1    Galoforo, S.S.2    Berns, C.M.3    Chen, J.C.4    Davis, B.H.5    Sim, J.E.6    Corry, P.M.7    Spitz, D.R.8
  • 52
    • 0034652599 scopus 로고    scopus 로고
    • Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in human breast carcinoma cells
    • Lee YJ, Galoforo SS, Sim JE, Ridnour LA, Choi J, Forman HJ, Corry PM, Spitz DR: Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in human breast carcinoma cells. Free Radic Biol Med 28: 575-584, 2000
    • (2000) Free Radic Biol Med , vol.28 , pp. 575-584
    • Lee, Y.J.1    Galoforo, S.S.2    Sim, J.E.3    Ridnour, L.A.4    Choi, J.5    Forman, H.J.6    Corry, P.M.7    Spitz, D.R.8
  • 53
    • 17744364850 scopus 로고    scopus 로고
    • Cell cycle coupled variation in Topoisomerase IIα mRNA is regulated by the 3′-untranslated region: Possible role of redox sensitive protein binding in mRNA stability
    • Goswami PC, Sheren J, Albee LD, Parsian AJ, Sim JE, Ridnour LA, Higashikubo R, Hunt CR, Spitz DR: Cell cycle coupled variation in Topoisomerase IIα mRNA is regulated by the 3′-untranslated region: Possible role of redox sensitive protein binding in mRNA stability. J Biol Chem 275: 38384-38392, 2000
    • (2000) J Biol Chem , vol.275 , pp. 38384-38392
    • Goswami, P.C.1    Sheren, J.2    Albee, L.D.3    Parsian, A.J.4    Sim, J.E.5    Ridnour, L.A.6    Higashikubo, R.7    Hunt, C.R.8    Spitz, D.R.9
  • 56
    • 0041856170 scopus 로고    scopus 로고
    • Redox potential of human thioredoxin-1 and identification of a second dithiol/disulfide motif
    • Watson WH, Pohl J, Montfort WR, Stuchlik O, Reed MS, Powis G, Jones DP: Redox potential of human thioredoxin-1 and identification of a second dithiol/disulfide motif. J Biol Chem 278: 33408-33415, 2003
    • (2003) J Biol Chem , vol.278 , pp. 33408-33415
    • Watson, W.H.1    Pohl, J.2    Montfort, W.R.3    Stuchlik, O.4    Reed, M.S.5    Powis, G.6    Jones, D.P.7
  • 57
    • 0034859507 scopus 로고    scopus 로고
    • Zinc binding and redox control of p53 structure and function
    • Hainaut P, Mann K: Zinc binding and redox control of p53 structure and function. Antioxidants & Redox Signaling 3(4): 611-623, 2001
    • (2001) Antioxidants & Redox Signaling , vol.3 , Issue.4 , pp. 611-623
    • Hainaut, P.1    Mann, K.2
  • 58
    • 0034859653 scopus 로고    scopus 로고
    • Zinc finger proteins as molecular targets for nitric oxide-mediated gene regulation
    • Kroncke KD: Zinc finger proteins as molecular targets for nitric oxide-mediated gene regulation. Antioxidants & Redox Signaling 3(4): 565-575, 2001
    • (2001) Antioxidants & Redox Signaling , vol.3 , Issue.4 , pp. 565-575
    • Kroncke, K.D.1
  • 59
    • 0034873674 scopus 로고    scopus 로고
    • Oxidation of zinc-binding cysteine residues in transcription factor proteins
    • Wilcox DE, Schenk AD, Feldman BM, Xu Y: Oxidation of zinc-binding cysteine residues in transcription factor proteins. Antioxidants & Redox Signaling 3(4): 549-564, 2001
    • (2001) Antioxidants & Redox Signaling , vol.3 , Issue.4 , pp. 549-564
    • Wilcox, D.E.1    Schenk, A.D.2    Feldman, B.M.3    Xu, Y.4
  • 60
    • 0034859820 scopus 로고    scopus 로고
    • Oxidation of zinc finger transcription factors: Physiological consequences
    • Webster KA, Prentice H, Bishopric NH: Oxidation of zinc finger transcription factors: Physiological consequences. Antioxidants & Redox Signaling 3(4): 535-548, 2001
    • (2001) Antioxidants & Redox Signaling , vol.3 , Issue.4 , pp. 535-548
    • Webster, K.A.1    Prentice, H.2    Bishopric, N.H.3
  • 61
    • 0036912721 scopus 로고    scopus 로고
    • Nitric oxide as a unique signaling molecule in the vascular system: A historical overview
    • Ignarro LJ: Nitric oxide as a unique signaling molecule in the vascular system: A historical overview. J Physiol & Pharmacol 53(4 Pt 1): 503-514, 2002
    • (2002) J Physiol & Pharmacol , vol.53 , Issue.4 PART 1 , pp. 503-514
    • Ignarro, L.J.1
  • 62
    • 0031425115 scopus 로고    scopus 로고
    • A tutorial on the diffusibility and reactivity of free nitric oxide
    • Lancaster JR: A tutorial on the diffusibility and reactivity of free nitric oxide. Nitric Oxide 1(1): 18-30, 1997
    • (1997) Nitric Oxide , vol.1 , Issue.1 , pp. 18-30
    • Lancaster, J.R.1
  • 63
    • 0004707849 scopus 로고
    • Modifiers of free radicals inhibit in vitro the oncogenic actions of X-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate
    • Borek C, Troll W: Modifiers of free radicals inhibit in vitro the oncogenic actions of X-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. Proc Natl Acad Sci USA 80(5): 1304-1307, 1983
    • (1983) Proc Natl Acad Sci USA , vol.80 , Issue.5 , pp. 1304-1307
    • Borek, C.1    Troll, W.2
  • 64
    • 0028066981 scopus 로고
    • Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial
    • Delanian S, Baillet F, Huart J, Lefaix JL, Maulard C, Housset M: Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial. Radiother Oncol 32: 12-20, 1994
    • (1994) Radiother Oncol , vol.32 , pp. 12-20
    • Delanian, S.1    Baillet, F.2    Huart, J.3    Lefaix, J.L.4    Maulard, C.5    Housset, M.6
  • 68
    • 0035878875 scopus 로고    scopus 로고
    • Redox modulation of the pro-fibrogenic mediator plasminogen activator inhibitor-1
    • Zhao W, Spitz DR, Oberley LW Robbins MEC: Redox modulation of the pro-fibrogenic mediator plasminogen activator inhibitor-1. Cancer Res 61: 5537-5543, 2001
    • (2001) Cancer Res , vol.61 , pp. 5537-5543
    • Zhao, W.1    Spitz, D.R.2    Oberley, L.W.3    Robbins, M.E.C.4
  • 69
    • 0036791114 scopus 로고    scopus 로고
    • Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblasts
    • Azzam EI, de Toledo SM, Spitz DR, Little JB: Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblasts. Cancer Res 62: 5436-5442, 2002
    • (2002) Cancer Res , vol.62 , pp. 5436-5442
    • Azzam, E.I.1    De Toledo, S.M.2    Spitz, D.R.3    Little, J.B.4
  • 70
    • 0037013331 scopus 로고    scopus 로고
    • Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation
    • Leach JK, Black SM, Schmidt-Ullrich RK, Mikkelsen RB: Activation of constitutive nitric-oxide synthase activity is an early signaling event induced by ionizing radiation. J Biol Chem 277(18): 15400-15406, 2002
    • (2002) J Biol Chem , vol.277 , Issue.18 , pp. 15400-15406
    • Leach, J.K.1    Black, S.M.2    Schmidt-Ullrich, R.K.3    Mikkelsen, R.B.4
  • 71
    • 0035872421 scopus 로고    scopus 로고
    • Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen
    • Leach JK, Van Tuyle G, Lin PS, Schmidt-Ullrich R, Mikkelsen RB: Ionizing radiation-induced, mitochondria-dependent generation of reactive oxygen/nitrogen. Cancer Res 61(10): 3894-3901, 2001
    • (2001) Cancer Res , vol.61 , Issue.10 , pp. 3894-3901
    • Leach, J.K.1    Van Tuyle, G.2    Lin, P.S.3    Schmidt-Ullrich, R.4    Mikkelsen, R.B.5
  • 72
    • 0141673128 scopus 로고    scopus 로고
    • Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
    • Mikkelsen RB, Wardman P: Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene 22(37): 5734-5754, 2003
    • (2003) Oncogene , vol.22 , Issue.37 , pp. 5734-5754
    • Mikkelsen, R.B.1    Wardman, P.2
  • 74
    • 0017348934 scopus 로고
    • Mitochondrial production of superoxide radical and hydrogen peroxide
    • Boveris A: Mitochondrial production of superoxide radical and hydrogen peroxide. Adv Exp Med Biol 78: 67-82, 1977
    • (1977) Adv Exp Med Biol , vol.78 , pp. 67-82
    • Boveris, A.1
  • 75
    • 0038640479 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
    • Morgan WF: Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat Res 159: 581-596, 2003
    • (2003) Radiat Res , vol.159 , pp. 581-596
    • Morgan, W.F.1
  • 77
    • 0043269302 scopus 로고    scopus 로고
    • Function and structure of complex II of the respiratory chain
    • Cecchii G: Function and structure of complex II of the respiratory chain. Annu. Rev. Biochem. 72: 77-109, 2003
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 77-109
    • Cecchii, G.1
  • 79
    • 0002026429 scopus 로고    scopus 로고
    • Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
    • Lu CY, Lee HC, Fahn HJ, Wei YH: Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutation Res 423(1-2): 11-21, 1999
    • (1999) Mutation Res , vol.423 , Issue.1-2 , pp. 11-21
    • Lu, C.Y.1    Lee, H.C.2    Fahn, H.J.3    Wei, Y.H.4
  • 80
    • 0032413244 scopus 로고    scopus 로고
    • Mitochondrial aging: Open questions
    • Beckman KB, Ames BN: Mitochondrial aging: Open questions. Ann NY Acad Sci 854: 118-127, 1998
    • (1998) Ann NY Acad Sci , vol.854 , pp. 118-127
    • Beckman, K.B.1    Ames, B.N.2
  • 82
    • 0029765536 scopus 로고    scopus 로고
    • Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures
    • Clutton SM, Townsend KM, Walker C, Ansell JD, Wright EG: Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures. Carcinogenesis 17(8): 1633-1639, 1996
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1633-1639
    • Clutton, S.M.1    Townsend, K.M.2    Walker, C.3    Ansell, J.D.4    Wright, E.G.5
  • 84
    • 0023868539 scopus 로고
    • Inhibition of pentose cycle of A549 cells by 6-aminonicotinamide: Consequences for aerobic and hypoxic radiation response and for radiosensitizer action
    • Varnes ME: Inhibition of pentose cycle of A549 cells by 6-aminonicotinamide: Consequences for aerobic and hypoxic radiation response and for radiosensitizer action. NCI Monographs (6): 199-203, 1988
    • (1988) NCI Monographs , Issue.6 , pp. 199-203
    • Varnes, M.E.1
  • 86
    • 0037273063 scopus 로고    scopus 로고
    • Oxidative stress in ataxia telangiectasia
    • Watters DJ: Oxidative stress in ataxia telangiectasia. Redox Report 8(1): 23-29, 2003
    • (2003) Redox Report , vol.8 , Issue.1 , pp. 23-29
    • Watters, D.J.1
  • 87
    • 0034544555 scopus 로고    scopus 로고
    • Thioredoxin nuclear translocation and interaction with redox factor-1 activates the AP-1 transcription factor in response to ionizing radiation
    • Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, Spitz DR, Yodoi J, Gius D: Thioredoxin nuclear translocation and interaction with redox factor-1 activates the AP-1 transcription factor in response to ionizing radiation. Cancer Res 60: 6688-6695, 2000
    • (2000) Cancer Res , vol.60 , pp. 6688-6695
    • Wei, S.J.1    Botero, A.2    Hirota, K.3    Bradbury, C.M.4    Markovina, S.5    Laszlo, A.6    Spitz, D.R.7    Yodoi, J.8    Gius, D.9
  • 88
    • 0035870288 scopus 로고    scopus 로고
    • Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative stress-resistant cells
    • Bradbury CM, Locke JE, Wei SJ, Rene LM, Karimpour S, Hunt C, Spitz DR, Gius D: Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative stress-resistant cells. Cancer Res 61(8): 3486-3492, 2001
    • (2001) Cancer Res , vol.61 , Issue.8 , pp. 3486-3492
    • Bradbury, C.M.1    Locke, J.E.2    Wei, S.J.3    Rene, L.M.4    Karimpour, S.5    Hunt, C.6    Spitz, D.R.7    Gius, D.8
  • 93
    • 0347711117 scopus 로고    scopus 로고
    • NADPH oxidases: Not just for leukocytes anymore!
    • Bokoch GM, Knaus UG: NADPH oxidases: Not just for leukocytes anymore! Trends in Biochemical Sciences 28(9): 502-508, 2003
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.9 , pp. 502-508
    • Bokoch, G.M.1    Knaus, U.G.2
  • 94
    • 0042379916 scopus 로고    scopus 로고
    • The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
    • Cai H, Griendling KK, Harrison DG: The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends in Pharmacological Sciences 24(9): 471-478, 2003
    • (2003) Trends in Pharmacological Sciences , vol.24 , Issue.9 , pp. 471-478
    • Cai, H.1    Griendling, K.K.2    Harrison, D.G.3
  • 95
    • 0042062310 scopus 로고    scopus 로고
    • Chemical basis of inflammation-induced carcinogenesis
    • Ohshima H, Tatemichi M, Sawa T: Chemical basis of inflammation-induced carcinogenesis. Arch. Biochem Biophys 417(1): 3-11, 2003
    • (2003) Arch. Biochem Biophys , vol.417 , Issue.1 , pp. 3-11
    • Ohshima, H.1    Tatemichi, M.2    Sawa, T.3
  • 96
    • 0036089571 scopus 로고    scopus 로고
    • Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure
    • Sorescu D, Griendling KK: Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. Congestive Heart Failure 8(3): 132-140, 2002
    • (2002) Congestive Heart Failure , vol.8 , Issue.3 , pp. 132-140
    • Sorescu, D.1    Griendling, K.K.2
  • 97
    • 0242658550 scopus 로고    scopus 로고
    • Oxidative metabolism, gap junctions and ionizing radiation-induced bystander effect
    • Azzam EI, Toledo SM, Little JB: Oxidative metabolism, gap junctions and ionizing radiation-induced bystander effect. Oncogene 22: 7050-7057, 2003
    • (2003) Oncogene , vol.22 , pp. 7050-7057
    • Azzam, E.I.1    Toledo, S.M.2    Little, J.B.3
  • 98
    • 0029800785 scopus 로고    scopus 로고
    • Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase
    • Emerit I, Garban F, Vassy J, Levy A, Filipe P, Freitas J: Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase. Proc Natl Acad Sci USA 93(23): 12799-12804, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.23 , pp. 12799-12804
    • Emerit, I.1    Garban, F.2    Vassy, J.3    Levy, A.4    Filipe, P.5    Freitas, J.6
  • 99
    • 0024428198 scopus 로고
    • Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
    • Wong GH, Elwell JH, Oberley LW, Goeddel DV: Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor. Cell 58(5): 923-931, 1989
    • (1989) Cell , vol.58 , Issue.5 , pp. 923-931
    • Wong, G.H.1    Elwell, J.H.2    Oberley, L.W.3    Goeddel, D.V.4
  • 100
    • 0029898935 scopus 로고    scopus 로고
    • Occupational levels of radiation exposure induce surface expression of interleukin-2 receptors in stimulated human peripheral blood lymphocytes
    • Xu Y, Greenstock CL, Trivedi A, Mitchel RE: Occupational levels of radiation exposure induce surface expression of interleukin-2 receptors in stimulated human peripheral blood lymphocytes. Radiat Environ Biophys 35(2): 89-93, 1996
    • (1996) Radiat Environ Biophys , vol.35 , Issue.2 , pp. 89-93
    • Xu, Y.1    Greenstock, C.L.2    Trivedi, A.3    Mitchel, R.E.4
  • 101
    • 0036845222 scopus 로고    scopus 로고
    • Radiation-induced tumor necrosis factor-alpha expression: Clinical application of transcriptional and physical targeting of gene therapy
    • Weichselbaum RR, Kufe DW, Hellman S, Rasmussen HS, King CR, Fischer PH, Mauceri HJ: Radiation-induced tumor necrosis factor-alpha expression: Clinical application of transcriptional and physical targeting of gene therapy. Lancet Oncol 3(11): 665-671, 2002
    • (2002) Lancet Oncol , vol.3 , Issue.11 , pp. 665-671
    • Weichselbaum, R.R.1    Kufe, D.W.2    Hellman, S.3    Rasmussen, H.S.4    King, C.R.5    Fischer, P.H.6    Mauceri, H.J.7
  • 102
    • 0033770857 scopus 로고    scopus 로고
    • Increased low density lipoprotein degradation in aorta of irradiated mice is inhibited by preenrichment of low density lipoprotein with alpha-tocopherol
    • Tribble DL, Krauss RM, Chu BM, Gong EL, Kullgren BR, Nagy JO, La Belle M: Increased low density lipoprotein degradation in aorta of irradiated mice is inhibited by preenrichment of low density lipoprotein with alpha-tocopherol. J Lipid Res 41(10): 1666-1672, 2000
    • (2000) J Lipid Res , vol.41 , Issue.10 , pp. 1666-1672
    • Tribble, D.L.1    Krauss, R.M.2    Chu, B.M.3    Gong, E.L.4    Kullgren, B.R.5    Nagy, J.O.6    La Belle, M.7
  • 103
    • 0023272666 scopus 로고
    • Characterization of the adaptive response to ionizing radiation induced by low doses of X rays to human lymphocytes
    • Shadley JD, Afzal V, Wolff S: Characterization of the adaptive response to ionizing radiation induced by low doses of X rays to human lymphocytes. Radiat Res 111(3): 511-517, 1987
    • (1987) Radiat Res , vol.111 , Issue.3 , pp. 511-517
    • Shadley, J.D.1    Afzal, V.2    Wolff, S.3
  • 104
    • 0031977085 scopus 로고    scopus 로고
    • The adaptive response in radiobiology: Evolving insights and implications
    • Wolff S: The adaptive response in radiobiology: Evolving insights and implications. Environmental Health Perspectives 106(Suppl 1): 277-283, 1998
    • (1998) Environmental Health Perspectives , vol.106 , Issue.1 SUPPL. , pp. 277-283
    • Wolff, S.1
  • 105
    • 0032818198 scopus 로고    scopus 로고
    • Adaptive response induced by low levels of radiation. Summary and comments
    • Waldren CA: Adaptive response induced by low levels of radiation. Summary and comments. Human & Experimental Toxicology 18(7): 452-453, 1999
    • (1999) Human & Experimental Toxicology , vol.18 , Issue.7 , pp. 452-453
    • Waldren, C.A.1
  • 106
    • 0023235667 scopus 로고
    • Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts
    • Spitz DR, Dewey WC, Li GC: Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblasts. J Cell Physiol 131: 364-373, 1987
    • (1987) J Cell Physiol , vol.131 , pp. 364-373
    • Spitz, D.R.1    Dewey, W.C.2    Li, G.C.3
  • 109
    • 0034511928 scopus 로고    scopus 로고
    • Enhanced expression of microsomal epoxide hydrolase and glutathione S-transferase by imidazole correlates with the radioprotective effect
    • Lee AK, Cho CK, Kim MS, Kim SG: Enhanced expression of microsomal epoxide hydrolase and glutathione S-transferase by imidazole correlates with the radioprotective effect. Res Commun Mol Path Pharmacol 108(3-4): 155-165, 2000
    • (2000) Res Commun Mol Path Pharmacol , vol.108 , Issue.3-4 , pp. 155-165
    • Lee, A.K.1    Cho, C.K.2    Kim, M.S.3    Kim, S.G.4


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