Absence of the CD44 gene prevents sarcoma metastasis

Cancer Research

Volumn 62, Issue 8, 2002, Pages 2281-2286

  Weber, Georg F ^a,b   Bronson, Roderick T ^c   Ilagan, John ^a,b   Cantor, Harvey ^a,b   Schmits, Rudolf ^d,e   Mak, Tak W ^d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c TUFTS UNIVERSITY   (United States)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; HERMES ANTIGEN; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CARCINOGENESIS; CONTROLLED STUDY; GENE DISRUPTION; GENE MUTATION; KNOCKOUT MOUSE; METASTASIS; MOUSE; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; TUMOR GROWTH;

ANIMALS; ANTIGENS, CD44; BONE NEOPLASMS; FEMALE; GENE DELETION; INTESTINAL POLYPS; LIVER NEOPLASMS, EXPERIMENTAL; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOSARCOMA; POINT MUTATION; SPLENIC NEOPLASMS;

EID: 0037089521     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

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2. Prevention of tumor metastasis formation by anti-variant CD44
3. Receptor-ligand interaction between CD44 and osteopontin (Eta-1)
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5. Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function
6. Ras, protein kinase C ζ, and I κ B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-κ B by hyaluronic acid fragments in T-24 carcinoma cells
7. CD44s expression in human colon carcinomas influences growth of liver metastases
8. New reports blur image of promising metastasis marker
9. Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan
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14. Gene interaction and single gene effects in colon turnout susceptibility in mice
15. Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway
16. Lymphomas in genetically engineered mice
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19. Tumorigenesis in the multiple intestinal neoplasia mouse: Redundancy of negative regulators and specificity of modifiers
20. -/-;Min mice
21. Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin