-
1
-
-
0033963704
-
Oxidative stress and gene regulation
-
Allen R.G., and Tresini M. Oxidative stress and gene regulation. Free Radic. Biol. Med. 28 (2000) 463-499
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 463-499
-
-
Allen, R.G.1
Tresini, M.2
-
2
-
-
0034704178
-
Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength
-
Alonso G., Ambrosino C., Jones M., and Nebreda A.R. Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength. J. Biol. Chem. 275 (2000) 40641-40648
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40641-40648
-
-
Alonso, G.1
Ambrosino, C.2
Jones, M.3
Nebreda, A.R.4
-
3
-
-
0037214362
-
Negative feedback regulation of MKK6 mRNA stability by p38α mitogen-activated protein kinase
-
Ambrosino C., Mace G., Galban S., Fritsch C., Vintersten K., Black E., Gorospe M., and Nebreda A.R. Negative feedback regulation of MKK6 mRNA stability by p38α mitogen-activated protein kinase. Mol. Cell. Biol. 23 (2003) 370-381
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 370-381
-
-
Ambrosino, C.1
Mace, G.2
Galban, S.3
Fritsch, C.4
Vintersten, K.5
Black, E.6
Gorospe, M.7
Nebreda, A.R.8
-
4
-
-
0020508747
-
Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases
-
Ames B.N. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 221 (1983) 1256-1264
-
(1983)
Science
, vol.221
, pp. 1256-1264
-
-
Ames, B.N.1
-
5
-
-
0024376173
-
ras oncogenes in human cancer: a review
-
Bos J.L. ras oncogenes in human cancer: a review. Cancer Res. 49 (1989) 4682-4689
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
6
-
-
0041660960
-
Mechanism of p38 MAP kinase activation in vivo
-
Brancho D., Tanaka N., Jaeschke A., Ventura J.J., Kelkar N., Tanaka Y., Kyuuma M., Takeshita T., Flavell R.A., and Davis R.J. Mechanism of p38 MAP kinase activation in vivo. Genes Dev. 17 (2003) 1969-1978
-
(2003)
Genes Dev.
, vol.17
, pp. 1969-1978
-
-
Brancho, D.1
Tanaka, N.2
Jaeschke, A.3
Ventura, J.J.4
Kelkar, N.5
Tanaka, Y.6
Kyuuma, M.7
Takeshita, T.8
Flavell, R.A.9
Davis, R.J.10
-
7
-
-
0036613212
-
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
-
Bulavin D.V., Demidov O.N., Saito S., Kauraniemi P., Phillips C., Amundson S.A., Ambrosino C., Sauter G., Nebreda A.R., Anderson C.W., et al. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity. Nat. Genet. 31 (2002) 210-215
-
(2002)
Nat. Genet.
, vol.31
, pp. 210-215
-
-
Bulavin, D.V.1
Demidov, O.N.2
Saito, S.3
Kauraniemi, P.4
Phillips, C.5
Amundson, S.A.6
Ambrosino, C.7
Sauter, G.8
Nebreda, A.R.9
Anderson, C.W.10
-
8
-
-
1842483852
-
Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway
-
Bulavin D.V., Phillips C., Nannenga B., Timofeev O., Donehower L.A., Anderson C.W., Appella E., and Fornace Jr. A.J. Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway. Nat. Genet. 36 (2004) 343-350
-
(2004)
Nat. Genet.
, vol.36
, pp. 343-350
-
-
Bulavin, D.V.1
Phillips, C.2
Nannenga, B.3
Timofeev, O.4
Donehower, L.A.5
Anderson, C.W.6
Appella, E.7
Fornace Jr., A.J.8
-
9
-
-
0034671847
-
The p38 pathway provides negative feedback for Ras proliferative signaling
-
Chen G., Hitomi M., Han J., and Stacey D.W. The p38 pathway provides negative feedback for Ras proliferative signaling. J. Biol. Chem. 275 (2000) 38973-38980
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38973-38980
-
-
Chen, G.1
Hitomi, M.2
Han, J.3
Stacey, D.W.4
-
10
-
-
0035918227
-
Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1
-
Cho S.G., Lee Y.H., Park H.S., Ryoo K., Kang K.W., Park J., Eom S.J., Kim M.J., Chang T.S., Choi S.Y., et al. Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1. J. Biol. Chem. 276 (2001) 12749-12755
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12749-12755
-
-
Cho, S.G.1
Lee, Y.H.2
Park, H.S.3
Ryoo, K.4
Kang, K.W.5
Park, J.6
Eom, S.J.7
Kim, M.J.8
Chang, T.S.9
Choi, S.Y.10
-
11
-
-
0027405704
-
Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
-
Church S.L., Grant J.W., Ridnour L.A., Oberley L.W., Swanson P.E., Meltzer P.S., and Trent J.M. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc. Natl. Acad. Sci. USA 90 (1993) 3113-3117
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3113-3117
-
-
Church, S.L.1
Grant, J.W.2
Ridnour, L.A.3
Oberley, L.W.4
Swanson, P.E.5
Meltzer, P.S.6
Trent, J.M.7
-
12
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley S., Paterson H., Kemp P., and Marshall C.J. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77 (1994) 841-852
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
13
-
-
11244287542
-
Dose-dependent inhibition of thyroid differentiation by RAS oncogenes
-
De Vita G., Bauer L., da Costa V.M., De Felice M., Baratta M.G., De Menna M., and Di Lauro R. Dose-dependent inhibition of thyroid differentiation by RAS oncogenes. Mol. Endocrinol. 19 (2005) 76-89
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 76-89
-
-
De Vita, G.1
Bauer, L.2
da Costa, V.M.3
De Felice, M.4
Baratta, M.G.5
De Menna, M.6
Di Lauro, R.7
-
14
-
-
0037163046
-
Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1
-
Dorion S., Lambert H., and Landry J. Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1. J. Biol. Chem. 277 (2002) 30792-30797
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30792-30797
-
-
Dorion, S.1
Lambert, H.2
Landry, J.3
-
15
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer 3 (2003) 11-22
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
16
-
-
0038471347
-
Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy
-
Elenitoba-Johnson K.S., Jenson S.D., Abbott R.T., Palais R.A., Bohling S.D., Lin Z., Tripp S., Shami P.J., Wang L.Y., Coupland R.W., et al. Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy. Proc. Natl. Acad. Sci. USA 100 (2003) 7259-7264
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7259-7264
-
-
Elenitoba-Johnson, K.S.1
Jenson, S.D.2
Abbott, R.T.3
Palais, R.A.4
Bohling, S.D.5
Lin, Z.6
Tripp, S.7
Shami, P.J.8
Wang, L.Y.9
Coupland, R.W.10
-
17
-
-
20344386238
-
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling
-
Emerling B.M., Platanias L.C., Black E., Nebreda A.R., Davis R.J., and Chandel N.S. Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol. Cell. Biol. 25 (2005) 4853-4862
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4853-4862
-
-
Emerling, B.M.1
Platanias, L.C.2
Black, E.3
Nebreda, A.R.4
Davis, R.J.5
Chandel, N.S.6
-
18
-
-
0035902115
-
Proliferation, cell cycle, and apoptosis in cancer
-
Evan G.I., and Vousden K.H. Proliferation, cell cycle, and apoptosis in cancer. Nature 411 (2001) 342-348
-
(2001)
Nature
, vol.411
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
19
-
-
28344447038
-
p38α MAPK is required for contact inhibition
-
Faust D., Dolado I., Cuadrado A., Oesch F., Weiss C., Nebreda A.R., and Dietrich C. p38α MAPK is required for contact inhibition. Oncogene 24 (2005) 7941-7945
-
(2005)
Oncogene
, vol.24
, pp. 7941-7945
-
-
Faust, D.1
Dolado, I.2
Cuadrado, A.3
Oesch, F.4
Weiss, C.5
Nebreda, A.R.6
Dietrich, C.7
-
20
-
-
0020057408
-
Correlation between the loss of the transformed phenotype and an increase in superoxide dismutase activity in a revertant subclone of sarcoma virus-infected mammalian cells
-
Fernandez-Pol J.A., Hamilton P.D., and Klos D.J. Correlation between the loss of the transformed phenotype and an increase in superoxide dismutase activity in a revertant subclone of sarcoma virus-infected mammalian cells. Cancer Res. 42 (1982) 609-617
-
(1982)
Cancer Res.
, vol.42
, pp. 609-617
-
-
Fernandez-Pol, J.A.1
Hamilton, P.D.2
Klos, D.J.3
-
21
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
22
-
-
0034961888
-
Role of reactive oxygen species in cell signalling pathways
-
Hancock J.T., Desikan R., and Neill S.J. Role of reactive oxygen species in cell signalling pathways. Biochem. Soc. Trans. 29 (2001) 345-350
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 345-350
-
-
Hancock, J.T.1
Desikan, R.2
Neill, S.J.3
-
23
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K., Xia Y., Zweier J.L., Sollott S.J., Der C.J., Fearon E.R., Sundaresan M., Finkel T., and Goldschmidt-Clermont P.J. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275 (1997) 1649-1652
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
24
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K., Hirao A., Arai F., Takubo K., Matsuoka S., Miyamoto K., Ohmura M., Naka K., Hosokawa K., Ikeda Y., and Suda T. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 12 (2006) 446-451
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
25
-
-
0032889677
-
Redox regulation of cellular signalling
-
Kamata H., and Hirata H. Redox regulation of cellular signalling. Cell. Signal. 11 (1999) 1-14
-
(1999)
Cell. Signal.
, vol.11
, pp. 1-14
-
-
Kamata, H.1
Hirata, H.2
-
26
-
-
0141723393
-
Role of JNK in tumor development
-
Kennedy N.J., and Davis R.J. Role of JNK in tumor development. Cell Cycle 2 (2003) 199-201
-
(2003)
Cell Cycle
, vol.2
, pp. 199-201
-
-
Kennedy, N.J.1
Davis, R.J.2
-
27
-
-
0141482096
-
p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells
-
Kim M.S., Lee E.J., Kim H.R., and Moon A. p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells. Cancer Res. 63 (2003) 5454-5461
-
(2003)
Cancer Res.
, vol.63
, pp. 5454-5461
-
-
Kim, M.S.1
Lee, E.J.2
Kim, H.R.3
Moon, A.4
-
28
-
-
0034604540
-
Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
-
Kurata S. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. J. Biol. Chem. 275 (2000) 23413-23416
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23413-23416
-
-
Kurata, S.1
-
29
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
Lavoie J.N., L'Allemain G., Brunet A., Muller R., and Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J. Biol. Chem. 271 (1996) 20608-20616
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
30
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee A.C., Fenster B.E., Ito H., Takeda K., Bae N.S., Hirai T., Yu Z.X., Ferrans V.J., Howard B.H., and Finkel T. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J. Biol. Chem. 274 (1999) 7936-7940
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
31
-
-
0037742410
-
p38 mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2
-
Li S.P., Junttila M.R., Han J., Kahari V.M., and Westermarck J. p38 mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2. Cancer Res. 63 (2003) 3473-3477
-
(2003)
Cancer Res.
, vol.63
, pp. 3473-3477
-
-
Li, S.P.1
Junttila, M.R.2
Han, J.3
Kahari, V.M.4
Westermarck, J.5
-
32
-
-
11144219953
-
Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis
-
Maciag A., and Anderson L.M. Reactive oxygen species and lung tumorigenesis by mutant K-ras: a working hypothesis. Exp. Lung Res. 31 (2005) 83-104
-
(2005)
Exp. Lung Res.
, vol.31
, pp. 83-104
-
-
Maciag, A.1
Anderson, L.M.2
-
33
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour S.J., Matten W.T., Hermann A.S., Candia J.M., Rong S., Fukasawa K., Vande Woude G.F., and Ahn N.G. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265 (1994) 966-970
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Vande Woude, G.F.7
Ahn, N.G.8
-
34
-
-
9144253936
-
The ASK1-MAP kinase cascades in mammalian stress response
-
Matsukawa J., Matsuzawa A., Takeda K., and Ichijo H. The ASK1-MAP kinase cascades in mammalian stress response. J. Biochem. 136 (2004) 261-265
-
(2004)
J. Biochem.
, vol.136
, pp. 261-265
-
-
Matsukawa, J.1
Matsuzawa, A.2
Takeda, K.3
Ichijo, H.4
-
35
-
-
2442693092
-
The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation
-
Mitsushita J., Lambeth J.D., and Kamata T. The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation. Cancer Res. 64 (2004) 3580-3585
-
(2004)
Cancer Res.
, vol.64
, pp. 3580-3585
-
-
Mitsushita, J.1
Lambeth, J.D.2
Kamata, T.3
-
36
-
-
33846283851
-
Hypoxia-induced assembly of prolyl-hydroxylase, PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2
-
Nakayama K., Gazdoiu S., Abraham R., Pan Z.Q., and Ronai Z. Hypoxia-induced assembly of prolyl-hydroxylase, PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2. Biochem. J. 401 (2007) 217-226
-
(2007)
Biochem. J.
, vol.401
, pp. 217-226
-
-
Nakayama, K.1
Gazdoiu, S.2
Abraham, R.3
Pan, Z.Q.4
Ronai, Z.5
-
37
-
-
0034213138
-
p38 MAP kinases: beyond the stress response
-
Nebreda A.R., and Porras A. p38 MAP kinases: beyond the stress response. Trends Biochem. Sci. 25 (2000) 257-260
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 257-260
-
-
Nebreda, A.R.1
Porras, A.2
-
38
-
-
28444479841
-
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells
-
Nicke B., Bastien J., Khanna S.J., Warne P.H., Cowling V., Cook S.J., Peters G., Delpuech O., Schulze A., Berns K., et al. Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells. Mol. Cell 20 (2005) 673-685
-
(2005)
Mol. Cell
, vol.20
, pp. 673-685
-
-
Nicke, B.1
Bastien, J.2
Khanna, S.J.3
Warne, P.H.4
Cowling, V.5
Cook, S.J.6
Peters, G.7
Delpuech, O.8
Schulze, A.9
Berns, K.10
-
39
-
-
16244382057
-
Glutathione S-transferase genotypes and cancer risk
-
Parl F.F. Glutathione S-transferase genotypes and cancer risk. Cancer Lett. 221 (2005) 123-129
-
(2005)
Cancer Lett.
, vol.221
, pp. 123-129
-
-
Parl, F.F.1
-
40
-
-
0742270609
-
P38 α mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli
-
Porras A., Zuluaga S., Black E., Valladares A., Alvarez A.M., Ambrosino C., Benito M., and Nebreda A.R. P38 α mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Mol. Biol. Cell 15 (2004) 922-933
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 922-933
-
-
Porras, A.1
Zuluaga, S.2
Black, E.3
Valladares, A.4
Alvarez, A.M.5
Ambrosino, C.6
Benito, M.7
Nebreda, A.R.8
-
41
-
-
2542458262
-
p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor
-
Qi X., Tang J., Pramanik R., Schultz R.M., Shirasawa S., Sasazuki T., Han J., and Chen G. p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. J. Biol. Chem. 279 (2004) 22138-22144
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22138-22144
-
-
Qi, X.1
Tang, J.2
Pramanik, R.3
Schultz, R.M.4
Shirasawa, S.5
Sasazuki, T.6
Han, J.7
Chen, G.8
-
42
-
-
0035901606
-
Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals
-
Santillo M., Mondola P., Seru R., Annella T., Cassano S., Ciullo I., Tecce M.F., Iacomino G., Damiano S., Cuda G., et al. Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals. Curr. Biol. 11 (2001) 614-619
-
(2001)
Curr. Biol.
, vol.11
, pp. 614-619
-
-
Santillo, M.1
Mondola, P.2
Seru, R.3
Annella, T.4
Cassano, S.5
Ciullo, I.6
Tecce, M.F.7
Iacomino, G.8
Damiano, S.9
Cuda, G.10
-
43
-
-
0033135256
-
Hematopoietic growth factors signal through the formation of reactive oxygen species
-
Sattler M., Winkler T., Verma S., Byrne C.H., Shrikhande G., Salgia R., and Griffin J.D. Hematopoietic growth factors signal through the formation of reactive oxygen species. Blood 93 (1999) 2928-2935
-
(1999)
Blood
, vol.93
, pp. 2928-2935
-
-
Sattler, M.1
Winkler, T.2
Verma, S.3
Byrne, C.H.4
Shrikhande, G.5
Salgia, R.6
Griffin, J.D.7
-
44
-
-
0034637599
-
The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells
-
Sattler M., Verma S., Shrikhande G., Byrne C.H., Pride Y.B., Winkler T., Greenfield E.A., Salgia R., and Griffin J.D. The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells. J. Biol. Chem. 275 (2000) 24273-24278
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24273-24278
-
-
Sattler, M.1
Verma, S.2
Shrikhande, G.3
Byrne, C.H.4
Pride, Y.B.5
Winkler, T.6
Greenfield, E.A.7
Salgia, R.8
Griffin, J.D.9
-
45
-
-
0033517275
-
Cell transformation by the superoxide-generating oxidase Mox1
-
Suh Y.A., Arnold R.S., Lassegue B., Shi J., Xu X., Sorescu D., Chung A.B., Griendling K.K., and Lambeth J.D. Cell transformation by the superoxide-generating oxidase Mox1. Nature 401 (1999) 79-82
-
(1999)
Nature
, vol.401
, pp. 79-82
-
-
Suh, Y.A.1
Arnold, R.S.2
Lassegue, B.3
Shi, J.4
Xu, X.5
Sorescu, D.6
Chung, A.B.7
Griendling, K.K.8
Lambeth, J.D.9
-
46
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski T.P., and Nathan C.F. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51 (1991) 794-798
-
(1991)
Cancer Res.
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
47
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
Tobiume K., Matsuzawa A., Takahashi T., Nishitoh H., Morita K., Takeda K., Minowa O., Miyazono K., Noda T., and Ichijo H. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2 (2001) 222-228
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
48
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend D.M., and Tew K.D. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22 (2003) 7369-7375
-
(2003)
Oncogene
, vol.22
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
49
-
-
33746898269
-
Novel aspects of oxidative stress-associated carcinogenesis
-
Toyokuni S. Novel aspects of oxidative stress-associated carcinogenesis. Antioxid. Redox Signal. 8 (2006) 1373-1377
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1373-1377
-
-
Toyokuni, S.1
-
51
-
-
2342562556
-
Mitogen-activated protein kinases in apoptosis regulation
-
Wada T., and Penninger J.M. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23 (2004) 2838-2849
-
(2004)
Oncogene
, vol.23
, pp. 2838-2849
-
-
Wada, T.1
Penninger, J.M.2
-
52
-
-
0036242247
-
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
-
Wang W., Chen J.X., Liao R., Deng Q., Zhou J.J., Huang S., and Sun P. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol. Cell. Biol. 22 (2002) 3389-3403
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3389-3403
-
-
Wang, W.1
Chen, J.X.2
Liao, R.3
Deng, Q.4
Zhou, J.J.5
Huang, S.6
Sun, P.7
-
53
-
-
0036734148
-
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells
-
Weijzen S., Rizzo P., Braid M., Vaishnav R., Jonkheer S.M., Zlobin A., Osborne B.A., Gottipati S., Aster J.C., Hahn W.C., et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat. Med. 8 (2002) 979-986
-
(2002)
Nat. Med.
, vol.8
, pp. 979-986
-
-
Weijzen, S.1
Rizzo, P.2
Braid, M.3
Vaishnav, R.4
Jonkheer, S.M.5
Zlobin, A.6
Osborne, B.A.7
Gottipati, S.8
Aster, J.C.9
Hahn, W.C.10
-
54
-
-
0036174516
-
Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38
-
Wolfman J.C., Palmby T., Der C.J., and Wolfman A. Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38. Mol. Cell. Biol. 22 (2002) 1589-1606
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1589-1606
-
-
Wolfman, J.C.1
Palmby, T.2
Der, C.J.3
Wolfman, A.4
-
55
-
-
2642527955
-
Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation
-
Woo R.A., and Poon R.Y. Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation. Genes Dev. 18 (2004) 1317-1330
-
(2004)
Genes Dev.
, vol.18
, pp. 1317-1330
-
-
Woo, R.A.1
Poon, R.Y.2
-
56
-
-
0034625170
-
MEK kinase 1 is critically required for c-jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
-
Xia Y., Makris C., Su B., Li E., Yang J., Nemerow G.R., and Karin M. MEK kinase 1 is critically required for c-jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc. Natl. Acad. Sci. USA 97 (2000) 5243-5248
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5243-5248
-
-
Xia, Y.1
Makris, C.2
Su, B.3
Li, E.4
Yang, J.5
Nemerow, G.R.6
Karin, M.7
-
57
-
-
0032483967
-
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption
-
Yujiri T., Sather S., Fanger G.R., and Johnson G.L. Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption. Science 282 (2000) 1911-1914
-
(2000)
Science
, vol.282
, pp. 1911-1914
-
-
Yujiri, T.1
Sather, S.2
Fanger, G.R.3
Johnson, G.L.4
|