메뉴 건너뛰기




Volumn 14, Issue 10, 2013, Pages 20930-20953

MicroRNA-regulated pathways in hematological malignancies: How to avoid cells playing out of tune

Author keywords

Leukemia; Lymphoma; microRNA

Indexed keywords

4 PHENYLBUTYRIC ACID; 5 AZA 2' DEOXYCYTIDINE; ANTISENSE OLIGONUCLEOTIDE; AZACITIDINE; CALCITRIOL; CYTARABINE; IMATINIB; MICRORNA; MICRORNA 125; MICRORNA 146; MICRORNA 155; MICRORNA 17-92; MICRORNA 196B; MICRORNA 223; MICRORNA 26; MICRORNA 29; MICRORNA 29B; MICRORNA 328; MICRORNA 34; MICRORNA 34A; NANOPARTICLE; NICOTINAMIDE; TRANSFERRIN; UNCLASSIFIED DRUG;

EID: 84886892835     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141020930     Document Type: Review
Times cited : (22)

References (126)
  • 1
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D.P. MicroRNAs: Target recognition and regulatory functions. Cell 2009, 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 2
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim, V.N. MicroRNA biogenesis: Coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 2005, 6, 376-385.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 4
    • 84880921276 scopus 로고    scopus 로고
    • Adult-specific functions of animal microRNAs
    • Sun, K.; Lai, E.C. Adult-specific functions of animal microRNAs. Nat. Rev. Genet. 2013, 14, 535-548.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 535-548
    • Sun, K.1    Lai, E.C.2
  • 5
    • 0037315894 scopus 로고    scopus 로고
    • Disruption of differentiation in human cancer: AML shows the way
    • Tenen, D.G. Disruption of differentiation in human cancer: AML shows the way. Nat. Rev. Cancer 2003, 3, 89-101.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 89-101
    • Tenen, D.G.1
  • 6
    • 84857079737 scopus 로고    scopus 로고
    • The microcosmos of cancer
    • Lujambio, A.; Lowe, S.W. The microcosmos of cancer. Nature 2012, 482, 347-355.
    • (2012) Nature , vol.482 , pp. 347-355
    • Lujambio, A.1    Lowe, S.W.2
  • 7
    • 35348837205 scopus 로고    scopus 로고
    • Hematopoietic developmental pathways: On cellular basis
    • Iwasaki, H.; Akashi, K. Hematopoietic developmental pathways: On cellular basis. Oncogene 2007, 26, 6687-6696.
    • (2007) Oncogene , vol.26 , pp. 6687-6696
    • Iwasaki, H.1    Akashi, K.2
  • 9
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: Balancing differentiation with transformation
    • Rosenbauer, F.; Tenen D.G. Transcription factors in myeloid development: Balancing differentiation with transformation. Nat. Rev. Immunol. 2007, 7, 105-117.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 10
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • Ebert, M.S.; Sharp, P.A. Roles for microRNAs in conferring robustness to biological processes. Cell 2012, 149, 515-524.
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 12
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell, R.M.; Rao, D.S.; Chaudhuri, A.A.; Baltimore, D. Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 2010, 10, 111-122.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 14
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • Ota, A.; Tagawa, H.; Karnan, S.; Tsuzuki, S.; Karpas, A.; Kira, S.; Yoshida, Y.; Seto, M. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 2004, 64, 3087-3095.
    • (2004) Cancer Res , vol.64 , pp. 3087-3095
    • Ota, A.1    Tagawa, H.2    Karnan, S.3    Tsuzuki, S.4    Karpas, A.5    Kira, S.6    Yoshida, Y.7    Seto, M.8
  • 26
    • 77951003346 scopus 로고    scopus 로고
    • microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
    • Zhao, J.J.; Lin, J.; Lwin, T.; Yang, H.; Guo, J.; Kong, W.; Dessureault, S.; Moscinski, L.C.; Rezania, D.; Dalton, W.S.; et al. microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. Blood 2010, 115, 2630-2639.
    • (2010) Blood , vol.115 , pp. 2630-2639
    • Zhao, J.J.1    Lin, J.2    Lwin, T.3    Yang, H.4    Guo, J.5    Kong, W.6    Dessureault, S.7    Moscinski, L.C.8    Rezania, D.9    Dalton, W.S.10
  • 27
    • 67650588646 scopus 로고    scopus 로고
    • MicroRNA-29b induces global DNA hypomethylation and tumour suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
    • Garzon, R.; Liu, S.; Fabbri, M.; Liu, Z.; Heaphy, C.E.; Callegari, E.; Schwind, S.; Pang, J.; Yu, J.; Muthusamy, N.; et al. MicroRNA-29b induces global DNA hypomethylation and tumour suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009, 113, 6411-6418.
    • (2009) Blood , vol.113 , pp. 6411-6418
    • Garzon, R.1    Liu, S.2    Fabbri, M.3    Liu, Z.4    Heaphy, C.E.5    Callegari, E.6    Schwind, S.7    Pang, J.8    Yu, J.9    Muthusamy, N.10
  • 31
    • 65549124181 scopus 로고    scopus 로고
    • miR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia
    • Pigazzi, M.; Manara, E.; Baron, E.; Basso, G. miR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia. Cancer Res. 2009, 69, 2471-2478.
    • (2009) Cancer Res. , vol.69 , pp. 2471-2478
    • Pigazzi, M.1    Manara, E.2    Baron, E.3    Basso, G.4
  • 34
    • 79959866409 scopus 로고    scopus 로고
    • Nicotinamide blocks proliferation and induces apoptosis ofchronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumour suppressor network
    • Audrito, V.; Vaisitti, T.; Rossi, D.; Gottardi, D.; D'Arena, G.; Laurenti, L.; Gaidano, G.; Malavasi, F.; Deaglio, S. Nicotinamide blocks proliferation and induces apoptosis ofchronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumour suppressor network. Cancer Res. 2011, 71, 4473-4483.
    • (2011) Cancer Res. , vol.71 , pp. 4473-4483
    • Audrito, V.1    Vaisitti, T.2    Rossi, D.3    Gottardi, D.4    D'Arena, G.5    Laurenti, L.6    Gaidano, G.7    Malavasi, F.8    Deaglio, S.9
  • 40
    • 78650658030 scopus 로고    scopus 로고
    • Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells
    • Zhong, X.; Li, N.; Liang, S.; Huang, Q.; Coukos, G.; Zhang, L. Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells. J. Biol. Chem. 2010, 285, 41961-41971.
    • (2010) J. Biol. Chem. , vol.285 , pp. 41961-41971
    • Zhong, X.1    Li, N.2    Liang, S.3    Huang, Q.4    Coukos, G.5    Zhang, L.6
  • 42
  • 47
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
    • Fazi, F.; Rosa, A.; Fatica, A.; Gelmetti, V.; de Marchis, M.L.; Nervi, C.; Bozzoni, I. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell 2005, 123, 819-831.
    • (2005) Cell , vol.123 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3    Gelmetti, V.4    de Marchis, M.L.5    Nervi, C.6    Bozzoni, I.7
  • 51
    • 0037071398 scopus 로고    scopus 로고
    • The proto-oncogene c-myc in hematopoietic development and leukemogenesis
    • Hoffman, B.; Amanullah, A.; Shafarenko, M.; Liebermann, D.A. The proto-oncogene c-myc in hematopoietic development and leukemogenesis. Oncogene 2002, 21, 3414-3421.
    • (2002) Oncogene , vol.21 , pp. 3414-3421
    • Hoffman, B.1    Amanullah, A.2    Shafarenko, M.3    Liebermann, D.A.4
  • 53
    • 0023854161 scopus 로고
    • The Eμ-Myc transgenic mouse: A model for high-incidence spontaneous lymphoma and leukemia of early B cells
    • Harris, A.W.; Pinkert, C.A.; Crawford, M.; Langdon, W.Y.; Brinster, R.L.; Adams, J.M. The Eμ-Myc transgenic mouse: A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J. Exp. Med. 1988, 167, 353-371.
    • (1988) J. Exp. Med , vol.167 , pp. 353-371
    • Harris, A.W.1    Pinkert, C.A.2    Crawford, M.3    Langdon, W.Y.4    Brinster, R.L.5    Adams, J.M.6
  • 54
    • 85117739221 scopus 로고    scopus 로고
    • c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations
    • Luo, H.; O'Neal, J.; Kreisel, F.; Le Beau, M.M.; Tomasson, M.H. c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Blood 2005, 106, 2542-2561.
    • (2005) Blood , vol.106 , pp. 2542-2561
    • Luo, H.1    O'Neal, J.2    Kreisel, F.3    Le Beau, M.M.4    Tomasson, M.H.5
  • 57
    • 1942503942 scopus 로고    scopus 로고
    • The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    • Cao, R.; Zhang, Y. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3. Curr. Opin. Genet. Dev. 2004, 14, 155-164.
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 58
    • 84861542135 scopus 로고    scopus 로고
    • MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein
    • Zhu, Y.; Lu, Y.; Zhang, Q.; Liu, J.J.; Li, T.J.; Yang, J.R.; Zeng, C.; Zhuang, S.M. MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein. Nucleic Acids Res. 2012, 40, 4615-4625.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 4615-4625
    • Zhu, Y.1    Lu, Y.2    Zhang, Q.3    Liu, J.J.4    Li, T.J.5    Yang, J.R.6    Zeng, C.7    Zhuang, S.M.8
  • 59
    • 84855349331 scopus 로고    scopus 로고
    • miR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumour suppressor in acute myeloid leukemia
    • Zheng, Y.S.; Zhang, H.; Zhang, X.J.; Feng, D.D.; Luo, X.Q.; Zeng, C.W.; Lin, K.Y.; Zhou, H.; Qu, L.H.; Zhang P.; et al. miR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumour suppressor in acute myeloid leukemia. Oncogene 2012, 31, 80-92.
    • (2012) Oncogene , vol.31 , pp. 80-92
    • Zheng, Y.S.1    Zhang, H.2    Zhang, X.J.3    Feng, D.D.4    Luo, X.Q.5    Zeng, C.W.6    Lin, K.Y.7    Zhou, H.8    Qu, L.H.9    Zhang, P.10
  • 61
    • 76649130555 scopus 로고    scopus 로고
    • Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
    • Kim, H.; Huang, W.; Jiang, X.; Pennicooke, B.; Park, P.J.; Johnson, M.D. Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship. Proc. Natl. Acad. Sci. USA 2010, 107, 2183-2188.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 2183-2188
    • Kim, H.1    Huang, W.2    Jiang, X.3    Pennicooke, B.4    Park, P.J.5    Johnson, M.D.6
  • 62
    • 84861499437 scopus 로고    scopus 로고
    • MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia
    • Wang, X.S.; Gong, J.N.; Yu, J.; Wang, F.; Zhang, X.H.; Yin, X.L.; Tan, Z.Q.; Luo, Z.M.; Yang, G.H.; Shen, C.; et al. MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. Blood 2012, 119, 4992-5004.
    • (2012) Blood , vol.119 , pp. 4992-5004
    • Wang, X.S.1    Gong, J.N.2    Yu, J.3    Wang, F.4    Zhang, X.H.5    Yin, X.L.6    Tan, Z.Q.7    Luo, Z.M.8    Yang, G.H.9    Shen, C.10
  • 63
    • 77949518018 scopus 로고    scopus 로고
    • MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
    • Han, Y.C.; Park, C.Y.; Bhagat, G.; Zhang, J.; Wang, Y.; Fan, J.B.; Liu, M.; Zou, Y.; Weissman, I.L.; Gu, H. MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J. Exp. Med. 2010, 207, 475-489.
    • (2010) J. Exp. Med. , vol.207 , pp. 475-489
    • Han, Y.C.1    Park, C.Y.2    Bhagat, G.3    Zhang, J.4    Wang, Y.5    Fan, J.B.6    Liu, M.7    Zou, Y.8    Weissman, I.L.9    Gu, H.10
  • 64
    • 84863012417 scopus 로고    scopus 로고
    • Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia
    • Sampath, D.; Liu, C.; Vasan, K.; Sulda, M.; Puduvalli, V.K.; Wierda, W.G.; Keating, M.J. Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia. Blood 2012, 119, 1162-1172.
    • (2012) Blood , vol.119 , pp. 1162-1172
    • Sampath, D.1    Liu, C.2    Vasan, K.3    Sulda, M.4    Puduvalli, V.K.5    Wierda, W.G.6    Keating, M.J.7
  • 67
    • 84940234906 scopus 로고    scopus 로고
    • MicroRNAs and RNA-binding proteins: A complex network of interactions and reciprocal regulations in cancer
    • Ciafrè, S.A.; Galardi, S. MicroRNAs and RNA-binding proteins: A complex network of interactions and reciprocal regulations in cancer. RNA Biol. 2013, 10, 935-943.
    • (2013) RNA Biol. , vol.10 , pp. 935-943
    • Ciafrè, S.A.1    Galardi, S.2
  • 68
    • 84867606040 scopus 로고    scopus 로고
    • Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas
    • Zhang, X.; Zhao, X.; Fiskus, W.; Lin, J.; Lwin, T.; Rao, R.; Zhang, Y.; Chan, J.C.; Fu, K.; Marquez, V.E.; et al. Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas. Cancer Cell 2012, 22, 506-523.
    • (2012) Cancer Cell , vol.22 , pp. 506-523
    • Zhang, X.1    Zhao, X.2    Fiskus, W.3    Lin, J.4    Lwin, T.5    Rao, R.6    Zhang, Y.7    Chan, J.C.8    Fu, K.9    Marquez, V.E.10
  • 70
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • Hermeking, H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 2010, 17, 193-199.
    • (2010) Cell Death Differ. , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 73
    • 80051590849 scopus 로고    scopus 로고
    • Restitution of tumour suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice
    • Pramanik, D.; Campbell, N.R.; Karikari, C.; Chivukula, R.; Kent, O.A.; Mendell, T.; Maitra, A. Restitution of tumour suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol. Cancer Ther. 2011, 10, 1470-1480.
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 1470-1480
    • Pramanik, D.1    Campbell, N.R.2    Karikari, C.3    Chivukula, R.4    Kent, O.A.5    Mendell, T.6    Maitra, A.7
  • 75
    • 79957900919 scopus 로고    scopus 로고
    • Systemic delivery of tumour suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumours in mice
    • Trang, P.; Wiggins, J.F.; Daige, C.L.; Cho, C.; Omotola, M.; Brown, D.; Weidhaas, J.B.; Bader, A.G.; Slack, F.J. Systemic delivery of tumour suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumours in mice. Mol. Ther. 2011, 19, 1116-1122.
    • (2011) Mol. Ther. , vol.19 , pp. 1116-1122
    • Trang, P.1    Wiggins, J.F.2    Daige, C.L.3    Cho, C.4    Omotola, M.5    Brown, D.6    Weidhaas, J.B.7    Bader, A.G.8    Slack, F.J.9
  • 77
    • 75649108622 scopus 로고    scopus 로고
    • An emerging player in the adaptive immune response: MicroRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes
    • Curtale, G.; Citarella, F.; Carissimi, C.; Goldoni, M.; Carucci, N.; Fulci, V.; Franceschini, D.; Meloni, F.; Barnaba, V.; Macino, G. An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Blood 2010, 115, 265-273.
    • (2010) Blood , vol.115 , pp. 265-273
    • Curtale, G.1    Citarella, F.2    Carissimi, C.3    Goldoni, M.4    Carucci, N.5    Fulci, V.6    Franceschini, D.7    Meloni, F.8    Barnaba, V.9    McIno, G.10
  • 79
    • 84875786889 scopus 로고    scopus 로고
    • The Yin and Yang of microRNAs: Leukemia and immunity
    • So, A.Y.; Zhao, J.L.; Baltimore, D. The Yin and Yang of microRNAs: Leukemia and immunity. Immunol. Rev. 2013, 253, 129-145.
    • (2013) Immunol. Rev. , vol.253 , pp. 129-145
    • So, A.Y.1    Zhao, J.L.2    Baltimore, D.3
  • 80
    • 70349242211 scopus 로고    scopus 로고
    • NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls beta-globin and G-CSF receptor expression
    • Starnes, L.M.; Sorrentino, A.; Pelosi, E.; Ballarino, M.; Morsilli, O.; Biffoni, M.; Santoro, S.; Felli, N.; Castelli, G.; de Marchis, M.L.; et al. NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls beta-globin and G-CSF receptor expression. Blood 2009, 114, 1753-1763.
    • (2009) Blood , vol.114 , pp. 1753-1763
    • Starnes, L.M.1    Sorrentino, A.2    Pelosi, E.3    Ballarino, M.4    Morsilli, O.5    Biffoni, M.6    Santoro, S.7    Felli, N.8    Castelli, G.9    de Marchis, M.L.10
  • 83
    • 84862222969 scopus 로고    scopus 로고
    • The microRNA-17-92 family of microRNA clusters in development and disease
    • Concepcion, C.P.; Bonetti, C.; Ventura, A. The microRNA-17-92 family of microRNA clusters in development and disease. Cancer J. 2012, 18, 262-267.
    • (2012) Cancer J. , vol.18 , pp. 262-267
    • Concepcion, C.P.1    Bonetti, C.2    Ventura, A.3
  • 85
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods, K.; Thomson, J.M.; Hammond, S.M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem. 2007, 282, 2130-2134.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 88
    • 84860755726 scopus 로고    scopus 로고
    • The miRNA-17-92 cluster mediates chemoresistance and enhances tumour growth in mantle cell lymphoma via PI3K/AKT pathway activation
    • Rao, E.; Jiang, C.; Ji, M.; Huang, X.; Iqbal, J.; Lenz, G.; Wright, G.; Staudt, L.M.; Zhao, Y.M.; McKeithan, T.W.; et al. The miRNA-17-92 cluster mediates chemoresistance and enhances tumour growth in mantle cell lymphoma via PI3K/AKT pathway activation. Leukemia 2012, 26, 1064-1072.
    • (2012) Leukemia , vol.26 , pp. 1064-1072
    • Rao, E.1    Jiang, C.2    Ji, M.3    Huang, X.4    Iqbal, J.5    Lenz, G.6    Wright, G.7    Staudt, L.M.8    Zhao, Y.M.9    McKeithan, T.W.10
  • 90
    • 77951757309 scopus 로고    scopus 로고
    • The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
    • Wong, P.; Iwasaki, M.; Somervaille, T.C.; Ficara, F.; Carico, C.; Arnold, C.; Chen, C.Z.; Cleary, M.L. The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res. 2010, 70, 3833-3842.
    • (2010) Cancer Res. , vol.70 , pp. 3833-3842
    • Wong, P.1    Iwasaki, M.2    Somervaille, T.C.3    Ficara, F.4    Carico, C.5    Arnold, C.6    Chen, C.Z.7    Cleary, M.L.8
  • 93
    • 80055100472 scopus 로고    scopus 로고
    • miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies
    • Lin, K.Y.; Zhang, X.; Feng, D.D.; Zhang, H.; Zeng, C.W.; Han, B.W.; Zhou, A.D.; Qu, L.H.; Xu, L.; Chen, Y. miR-125b, a target of CDX2, regulates cell differentiation through repression of the core binding factor in hematopoietic malignancies. J. Biol. Chem. 2011, 286, 38253-38263.
    • (2011) J. Biol. Chem. , vol.286 , pp. 38253-38263
    • Lin, K.Y.1    Zhang, X.2    Feng, D.D.3    Zhang, H.4    Zeng, C.W.5    Han, B.W.6    Zhou, A.D.7    Qu, L.H.8    Xu, L.9    Chen, Y.10
  • 96
    • 41449093809 scopus 로고    scopus 로고
    • B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element
    • Yin, Q.; Wang, X.; McBride, J.; Fewell, C.; Flemington, E. B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element. J. Biol. Chem. 2008, 283, 2654-2662.
    • (2008) J. Biol. Chem , vol.283 , pp. 2654-2662
    • Yin, Q.1    Wang, X.2    McBride, J.3    Fewell, C.4    Flemington, E.5
  • 101
    • 84861947624 scopus 로고    scopus 로고
    • miR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: Correlation with NPM1 and FLT3 mutation status
    • doi:10.1186/1756-8722-5-26
    • Faraoni, I.; Laterza, S.; Ardiri, D.; Ciardi, C.; Fazi, F.; Lo-Coco, F. miR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: Correlation with NPM1 and FLT3 mutation status. J. Hematol. Oncol. 2012, 5, doi:10.1186/1756-8722-5-26.
    • (2012) J. Hematol. Oncol. , vol.5
    • Faraoni, I.1    Laterza, S.2    Ardiri, D.3    Ciardi, C.4    Fazi, F.5    Lo-Coco, F.6
  • 102
    • 84885434601 scopus 로고    scopus 로고
    • MicroRNA dysregulation in acute myeloid leukemia
    • Croce, C.M. MicroRNA dysregulation in acute myeloid leukemia. J. Clin. Oncol. 2013, 31, 2065-2066.
    • (2013) J. Clin. Oncol. , vol.31 , pp. 2065-2066
    • Croce, C.M.1
  • 103
    • 77956565912 scopus 로고    scopus 로고
    • HOXA9 regulates miR-155 in hematopoietic cells
    • Hu, Y.L.; Fong, S.; Largman, C.; Shen, W.F. HOXA9 regulates miR-155 in hematopoietic cells. Nucleic Acids Res. 2010, 38, 5472-5478.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5472-5478
    • Hu, Y.L.1    Fong, S.2    Largman, C.3    Shen, W.F.4
  • 105
    • 70349331525 scopus 로고    scopus 로고
    • Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-miR-155 transgenic mice
    • Costinean, S.; Sandhu, S.K.; Pedersen, I.M.; Tili, E.; Trotta, R.; Perrotti, D.; Ciarlariello, D.; Neviani, P.; Harb, J.; Kauffman, L.R.; et al. Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-miR-155 transgenic mice. Blood 2009, 114, 1374-1382.
    • (2009) Blood , vol.114 , pp. 1374-1382
    • Costinean, S.1    Sandhu, S.K.2    Pedersen, I.M.3    Tili, E.4    Trotta, R.5    Perrotti, D.6    Ciarlariello, D.7    Neviani, P.8    Harb, J.9    Kauffman, L.R.10
  • 107
    • 9244257908 scopus 로고    scopus 로고
    • An Mll-dependent Hox program drives hematopoietic progenitor expansion
    • Ernst, P.; Mabon, M.; Davidson, A.J.; Zon, L.I.; Korsmeyer, S.J. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr. Biol. 2004, 14, 2063-2069.
    • (2004) Curr. Biol. , vol.14 , pp. 2063-2069
    • Ernst, P.1    Mabon, M.2    Davidson, A.J.3    Zon, L.I.4    Korsmeyer, S.J.5
  • 111
    • 29244433742 scopus 로고    scopus 로고
    • Leukemogenic MLL fusion proteins bind across a broad region of the Hoxa9 locus, promoting transcription and multiple histone modifications
    • Milne, T.A.; Martin, M.E.; Brock, H.W.; Slany, R.K.; Hess, J.L. Leukemogenic MLL fusion proteins bind across a broad region of the Hoxa9 locus, promoting transcription and multiple histone modifications. Cancer Res. 2005, 65, 11367-11374.
    • (2005) Cancer Res. , vol.65 , pp. 11367-11374
    • Milne, T.A.1    Martin, M.E.2    Brock, H.W.3    Slany, R.K.4    Hess, J.L.5
  • 113
    • 84863283403 scopus 로고    scopus 로고
    • miR-196b directly targets both Hoxa9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia
    • doi:10.1038/ncomms1681
    • Li, Z.; Huang, H.; Chen, P.; He, M.; Li, Y.; Arnovitz, S.; Jiang, X.; He, C.; Hyjek, E.; Zhang, J.; et al. miR-196b directly targets both Hoxa9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat. Commun. 2012, 3, doi:10.1038/ncomms1681.
    • (2012) Nat. Commun. , vol.3
    • Li, Z.1    Huang, H.2    Chen, P.3    He, M.4    Li, Y.5    Arnovitz, S.6    Jiang, X.7    He, C.8    Hyjek, E.9    Zhang, J.10
  • 114
    • 77957821737 scopus 로고    scopus 로고
    • Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of Hoxa genes in pediatric acute lymphoblastic leukemia
    • Schotte, D.; Lange-Turenhout, E.A.; Stumpel, D.J.; Stam, R.W.; Buijs-Gladdines, J.G.; Meijerink, J.P.; Pieters, R.; den Boer, M.L. Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of Hoxa genes in pediatric acute lymphoblastic leukemia. Haematologica 2010, 95, 1675-1682.
    • (2010) Haematologica , vol.95 , pp. 1675-1682
    • Schotte, D.1    Lange-Turenhout, E.A.2    Stumpel, D.J.3    Stam, R.W.4    Buijs-Gladdines, J.G.5    Meijerink, J.P.6    Pieters, R.7    den Boer, M.L.8
  • 115
    • 84863105116 scopus 로고    scopus 로고
    • miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis
    • Bai, H.; Cao, Z.; Deng, C.; Zhou, L.; Wang, C. miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis. J. Cancer Res. Clin. Oncol. 2012, 138, 595-602.
    • (2012) J. Cancer Res. Clin. Oncol. , vol.138 , pp. 595-602
    • Bai, H.1    Cao, Z.2    Deng, C.3    Zhou, L.4    Wang, C.5
  • 116
    • 80053375836 scopus 로고    scopus 로고
    • MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of Ara-C-induced apoptosis
    • Gocek, E.; Wang, X.; Liu, X.; Liu, C.G.; Studzinski, G.P. MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of Ara-C-induced apoptosis. Cancer Res. 2011, 71, 6230-6239.
    • (2011) Cancer Res. , vol.71 , pp. 6230-6239
    • Gocek, E.1    Wang, X.2    Liu, X.3    Liu, C.G.4    Studzinski, G.P.5
  • 117
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy
    • Christman, J.K. 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy. Oncogene 2002, 21, 5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 119
    • 84876143666 scopus 로고    scopus 로고
    • Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: A novel epigenetic-targeting approach in acute myeloid leukemia
    • Mims, A.; Walker, A.R.; Huang, X.; Sun, J.; Wang, H.; Santhanam, R.; Dorrance, A.M.; Walker, C.; Hoellerbauer, P.; Tarighat, S.S.; et al. Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: A novel epigenetic-targeting approach in acute myeloid leukemia. Leukemia 2013, 27, 871-878.
    • (2013) Leukemia , vol.27 , pp. 871-878
    • Mims, A.1    Walker, A.R.2    Huang, X.3    Sun, J.4    Wang, H.5    Santhanam, R.6    Dorrance, A.M.7    Walker, C.8    Hoellerbauer, P.9    Tarighat, S.S.10
  • 120
    • 84877097246 scopus 로고    scopus 로고
    • Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: A novel therapeutic strategy in acute myeloid leukemia
    • Huang, X.; Schwind, S.; Yu, B.; Santhanam, R.; Wang, H.; Hoellerbauer, P.; Mims, A.; Klisovic, R.; Walker, A.R.; Chan, K.K.; et al. Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: A novel therapeutic strategy in acute myeloid leukemia. Clin. Cancer Res. 2013, 19, 2355-2367.
    • (2013) Clin. Cancer Res. , vol.19 , pp. 2355-2367
    • Huang, X.1    Schwind, S.2    Yu, B.3    Santhanam, R.4    Wang, H.5    Hoellerbauer, P.6    Mims, A.7    Klisovic, R.8    Walker, A.R.9    Chan, K.K.10
  • 123
    • 44449085896 scopus 로고    scopus 로고
    • Linking miRNA regulation to BCR-ABL expression: The next dimension
    • Faber, J.; Gregory, R.I.; Armstrong, S.A. Linking miRNA regulation to BCR-ABL expression: The next dimension. Cancer Cell 2008, 13, 467-469.
    • (2008) Cancer Cell , vol.13 , pp. 467-469
    • Faber, J.1    Gregory, R.I.2    Armstrong, S.A.3
  • 124
    • 84883561421 scopus 로고    scopus 로고
    • Imatinib induces demethylation of miR-203 gene: An epigenetic mechanism of anti-tumor effect of imatinib
    • Shibuta, T.; Honda, E.; Shiotsu, H.; Tanaka, Y.; Vellasamy, S.; Shiratsuchi, M.; Umemura, T. Imatinib induces demethylation of miR-203 gene: An epigenetic mechanism of anti-tumor effect of imatinib. Leuk. Res. 2013, 37, 1278-1286.
    • (2013) Leuk. Res. , vol.37 , pp. 1278-1286
    • Shibuta, T.1    Honda, E.2    Shiotsu, H.3    Tanaka, Y.4    Vellasamy, S.5    Shiratsuchi, M.6    Umemura, T.7
  • 125
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics. MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy
    • Kasinski, A.L.; Slack, F.J. Epigenetics and genetics. MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11, 849-864.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 126
    • 84875200257 scopus 로고    scopus 로고
    • Long noncoding RNAs: Cellular address codes in development and disease
    • Batista, P.J.; Chang, H.Y. Long noncoding RNAs: Cellular address codes in development and disease. Cell 2013, 152, 1298-1307.
    • (2013) Cell , vol.152 , pp. 1298-1307
    • Batista, P.J.1    Chang, H.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.