-
1
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 2003; 3: 89-101.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
2
-
-
79960066925
-
Genetic abnormalities and challenges in the treatment of acute myeloid leukemia
-
Kumar CC. Genetic abnormalities and challenges in the treatment of acute myeloid leukemia. Genes Cancer 2011; 2: 95-107.
-
(2011)
Genes Cancer
, vol.2
, pp. 95-107
-
-
Kumar, C.C.1
-
3
-
-
17444369333
-
Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells
-
Manfredini R, Trevisan F, Grande A, Tagliafico E, Montanari M, Lemoli R et al. Induction of a functional vitamin D receptor in all-trans-retinoic acid-induced monocytic differentiation of M2-type leukemic blast cells. Cancer Res 1999; 59: 3803-3811.
-
(1999)
Cancer Res
, vol.59
, pp. 3803-3811
-
-
Manfredini, R.1
Trevisan, F.2
Grande, A.3
Tagliafico, E.4
Montanari, M.5
Lemoli, R.6
-
4
-
-
27144560218
-
Translational study of vitamin D differentiation therapy of myeloid leukemia: Effects of the combination with a p38 MAPK inhibitor and an antioxidant
-
Wang Q, Harrison JS, Uskokovic M, Kutner A, Studzinski GP. Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant. Leukemia 2005; 19: 1812-1817.
-
(2005)
Leukemia
, vol.19
, pp. 1812-1817
-
-
Wang, Q.1
Harrison, J.S.2
Uskokovic, M.3
Kutner, A.4
Studzinski, G.P.5
-
5
-
-
33750064270
-
Identification of a molecular signature predictive of sensitivity to differentiation induction in acute myeloid leukemia
-
Tagliafico E, Tenedini E, Manfredini R, Grande A, Ferrari F, Roncaglia E et al. Identification of a molecular signature predictive of sensitivity to differentiation induction in acute myeloid leukemia. Leukemia 2006; 20: 1751-1758.
-
(2006)
Leukemia
, vol.20
, pp. 1751-1758
-
-
Tagliafico, E.1
Tenedini, E.2
Manfredini, R.3
Grande, A.4
Ferrari, F.5
Roncaglia, E.6
-
6
-
-
0030065422
-
Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
-
Liu M, Lee MH, Cohen M, Bommakanti M, Freedman LP. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev 1996; 10: 142-153.
-
(1996)
Genes Dev
, vol.10
, pp. 142-153
-
-
Liu, M.1
Lee, M.H.2
Cohen, M.3
Bommakanti, M.4
Freedman, L.P.5
-
7
-
-
0031788329
-
P21Cip1/WAF1 is important for differentiation and survival of U937 cells
-
Asada M, Yamada T, Fukumuro K, Mizutani S. p21Cip1/WAF1 is important for differentiation and survival of U937 cells. Leukemia 1998; 12: 1944-1950.
-
(1998)
Leukemia
, vol.12
, pp. 1944-1950
-
-
Asada, M.1
Yamada, T.2
Fukumuro, K.3
Mizutani, S.4
-
8
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K et al. Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J 1999; 18: 1223-1234.
-
(1999)
EMBO J
, vol.18
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
-
9
-
-
84856758666
-
MicroRNAs in acute leukemia: From biological players to clinical contributors
-
Schotte D, Pieters R, Den Boer ML. MicroRNAs in acute leukemia: from biological players to clinical contributors. Leukemia 2012; 26: 1-12.
-
(2012)
Leukemia
, vol.26
, pp. 1-12
-
-
Schotte, D.1
Pieters, R.2
Den Boer, M.L.3
-
10
-
-
80053375836
-
MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis
-
Gocek E, Wang X, Liu X, Liu CG, Studzinski GP. MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis. Cancer Res 2011; 71: 6230-6239.
-
(2011)
Cancer Res
, vol.71
, pp. 6230-6239
-
-
Gocek, E.1
Wang, X.2
Liu, X.3
Liu, C.G.4
Studzinski, G.P.5
-
11
-
-
62449121929
-
MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3
-
Wang X, Gocek E, Liu CG, Studzinski GP. MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3. Cell Cycle 2009; 8: 736-741.
-
(2009)
Cell Cycle
, vol.8
, pp. 736-741
-
-
Wang, X.1
Gocek, E.2
Liu, C.G.3
Studzinski, G.P.4
-
12
-
-
79952830167
-
Myc roles in hematopoiesis and leukemia
-
Delgado MD, León J. Myc roles in hematopoiesis and leukemia. Genes Cancer 2010; 1: 605-616.
-
(2010)
Genes Cancer
, vol.1
, pp. 605-616
-
-
Delgado, M.D.1
León, J.2
-
13
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6: 635-645.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
14
-
-
79952694643
-
Myc: Maestro of microRNAs
-
Bui TV, Mendell JT. Myc: maestro of microRNAs. Genes Cancer 2010; 1: 568-575.
-
(2010)
Genes Cancer
, vol.1
, pp. 568-575
-
-
Bui, T.V.1
Mendell, J.T.2
-
15
-
-
0034616116
-
Reciprocal regulation via protein-protein interaction between c-Myc and p21 (cip1/waf1/sdi1) in DNA replication and transcription
-
Kitaura H, Shinshi M, Uchikoshi Y, Ono T, Iguchi-Ariga SM, Ariga H. Reciprocal regulation via protein-protein interaction between c-Myc and p21 (cip1/waf1/sdi1) in DNA replication and transcription. J Biol Chem 2000; 275: 10477-10483.
-
(2000)
J Biol Chem
, vol.275
, pp. 10477-10483
-
-
Kitaura, H.1
Shinshi, M.2
Uchikoshi, Y.3
Ono, T.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
16
-
-
61349112251
-
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
-
Sander S, Bullinger L, Klapproth K, Fiedler K, Kestler HA, Barth TF et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 2008; 112: 4202-4212.
-
(2008)
Blood
, vol.112
, pp. 4202-4212
-
-
Sander, S.1
Bullinger, L.2
Klapproth, K.3
Fiedler, K.4
Kestler, H.A.5
Barth, T.F.6
-
17
-
-
80052999610
-
Critical role of c-Myc in acute myeloid leukemia involving direct regulation of miR-26a and histone methyltransferase EZH2
-
Salvatori B, Iosue I, Djodji Damas N, Mangiavacchi A, Chiaretti S, Messina M et al. Critical role of c-Myc in acute myeloid leukemia involving direct regulation of miR-26a and histone methyltransferase EZH2. Genes Cancer 2011; 2: 585-592.
-
(2011)
Genes Cancer
, vol.2
, pp. 585-592
-
-
Salvatori, B.1
Iosue, I.2
Djodji Damas, N.3
Mangiavacchi, A.4
Chiaretti, S.5
Messina, M.6
-
18
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008; 40: 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
Wentzel, E.A.4
Arking, D.E.5
West, K.M.6
-
19
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009; 137: 1005-1017.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
-
20
-
-
84861542135
-
MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein
-
Zhu Y, Lu Y, Zhang Q, Liu JJ, Li TJ, Yang JR et al. MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein. Nucleic Acids Res 2012; 40: 4615-4625.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 4615-4625
-
-
Zhu, Y.1
Lu, Y.2
Zhang, Q.3
Liu, J.J.4
Li, T.J.5
Yang, J.R.6
-
21
-
-
78651411120
-
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2
-
Lu J, He ML, Wang L, Chen Y, Liu X, Dong Q et al. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res 2011; 71: 225-233.
-
(2011)
Cancer Res
, vol.71
, pp. 225-233
-
-
Lu, J.1
He, M.L.2
Wang, L.3
Chen, Y.4
Liu, X.5
Dong, Q.6
-
22
-
-
79961020784
-
Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways
-
Chen L, Zheng J, Zhang Y, Yang L, Wang J, Ni J et al. Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways. Mol Ther 2011; 19: 1521-1528.
-
(2011)
Mol Ther
, vol.19
, pp. 1521-1528
-
-
Chen, L.1
Zheng, J.2
Zhang, Y.3
Yang, L.4
Wang, J.5
Ni, J.6
-
23
-
-
84860363212
-
E2F7 represses a network of oscillating cell cycle genes to control S-phase progression
-
Westendorp B, Mokry M, Groot Koerkamp MJ, Holstege FC, Cuppen E, de Bruin A. E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res 2012; 40: 3511-3523.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 3511-3523
-
-
Westendorp, B.1
Mokry, M.2
Groot Koerkamp, M.J.3
Holstege, F.C.4
Cuppen, E.5
De Bruin, A.6
-
24
-
-
84860745157
-
MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
-
Donzelli S, Fontemaggi G, Fazi F, Di Agostino S, Padula F, Biagioni F et al. MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function. Cell Death Differ 2012; 19: 1038-1048.
-
(2012)
Cell Death Differ
, vol.19
, pp. 1038-1048
-
-
Donzelli, S.1
Fontemaggi, G.2
Fazi, F.3
Di Agostino, S.4
Padula, F.5
Biagioni, F.6
-
25
-
-
34347383305
-
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
-
Fontana L, Pelosi E, Greco P, Racanicchi S, Testa U, Liuzzi F et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat Cell Biol 2007; 9: 775-787.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 775-787
-
-
Fontana, L.1
Pelosi, E.2
Greco, P.3
Racanicchi, S.4
Testa, U.5
Liuzzi, F.6
-
26
-
-
80455164567
-
Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation
-
Pospisil V, Vargova K, Kokavec J, Rybarova J, Savvulidi F, Jonasova A et al. Epigenetic silencing of the oncogenic miR-17-92 cluster during PU.1-directed macrophage differentiation. EMBO J 2011; 30: 4450-4464.
-
(2011)
EMBO J
, vol.30
, pp. 4450-4464
-
-
Pospisil, V.1
Vargova, K.2
Kokavec, J.3
Rybarova, J.4
Savvulidi, F.5
Jonasova, A.6
-
27
-
-
61749085629
-
Atypical E2Fs: New players in the E2F transcription factor family
-
Lammens T, Li J, Leone G, De Veylder L. Atypical E2Fs: new players in the E2F transcription factor family. Trends Cell Biol 2009; 19: 111-118.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 111-118
-
-
Lammens, T.1
Li, J.2
Leone, G.3
De Veylder, L.4
-
28
-
-
76549124435
-
E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation
-
Deng Q, Wang Q, Zong WY, Zheng DL, Wen YX, Wang KS et al. E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation. Cancer Res 2010; 70: 782-791.
-
(2010)
Cancer Res
, vol.70
, pp. 782-791
-
-
Deng, Q.1
Wang, Q.2
Zong, W.Y.3
Zheng, D.L.4
Wen, Y.X.5
Wang, K.S.6
-
29
-
-
77449150365
-
The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis
-
Sozzani R, Maggio C, Giordo R, Umana E, Ascencio-Ibanez JT, Hanley-Bowdoin L et al. The E2FD/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis. Plant Mol Biol 2010; 72: 381-395.
-
(2010)
Plant Mol Biol
, vol.72
, pp. 381-395
-
-
Sozzani, R.1
Maggio, C.2
Giordo, R.3
Umana, E.4
Ascencio-Ibanez, J.T.5
Hanley-Bowdoin, L.6
-
30
-
-
79954847218
-
Loss of E2F7 expression is an early event in squamous differentiation and causes derepression of the key differentiation activator Sp1
-
Hazar-Rethinam M, Cameron SR, Dahler AL, Endo-Munoz LB, Smith L, Rickwood D et al. Loss of E2F7 expression is an early event in squamous differentiation and causes derepression of the key differentiation activator Sp1. J Invest Dermatol 2011; 131: 1077-1084.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1077-1084
-
-
Hazar-Rethinam, M.1
Cameron, S.R.2
Dahler, A.L.3
Endo-Munoz, L.B.4
Smith, L.5
Rickwood, D.6
-
31
-
-
79959998220
-
The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation
-
Sirma H, Kumar M, Meena JK, Witt B, Weise JM, Lechel A et al. The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation. Gastroenterology 2011; 141: 326-337.
-
(2011)
Gastroenterology
, vol.141
, pp. 326-337
-
-
Sirma, H.1
Kumar, M.2
Meena, J.K.3
Witt, B.4
Weise, J.M.5
Lechel, A.6
-
32
-
-
84859316621
-
Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma
-
Li L, Sarver AL, Alamgir S, Subramanian S. Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. Lab Invest 2012; 92: 571-583.
-
(2012)
Lab Invest
, vol.92
, pp. 571-583
-
-
Li, L.1
Sarver, A.L.2
Alamgir, S.3
Subramanian, S.4
-
33
-
-
0346874353
-
E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes
-
Di Stefano L, Jensen MR, Helin K. E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes. EMBO J 2003; 22: 6289-6298.
-
(2003)
EMBO J
, vol.22
, pp. 6289-6298
-
-
Di Stefano, L.1
Jensen, M.R.2
Helin, K.3
-
34
-
-
27144515981
-
Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription
-
Christensen J, Cloos P, Toftegaard U, Klinkenberg D, Bracken AP, Trinh E et al. Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription. Nucleic Acids Res 2005; 33: 5458-5470.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5458-5470
-
-
Christensen, J.1
Cloos, P.2
Toftegaard, U.3
Klinkenberg, D.4
Bracken, A.P.5
Trinh, E.6
-
35
-
-
77951757309
-
The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression
-
Wong P, Iwasaki M, Somervaille TC, Ficara F, Carico C, Arnold C et al. The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res 2010; 70: 3833-3842.
-
(2010)
Cancer Res
, vol.70
, pp. 3833-3842
-
-
Wong, P.1
Iwasaki, M.2
Somervaille, T.C.3
Ficara, F.4
Carico, C.5
Arnold, C.6
-
36
-
-
41149101523
-
MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression
-
Ivanovska I, Ball AS, Diaz RL, Magnus JF, Kibukawa M, Schelter JM et al. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol Cell Biol 2008; 28: 2167-2174.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2167-2174
-
-
Ivanovska, I.1
Ball, A.S.2
Diaz, R.L.3
Magnus, J.F.4
Kibukawa, M.5
Schelter, J.M.6
-
37
-
-
79952118835
-
Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer
-
Zhang B, Liu XX, He JR, Zhou CX, Guo M, He M et al. Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer. Carcinogenesis 2011; 32: 2-9.
-
(2011)
Carcinogenesis
, vol.32
, pp. 2-9
-
-
Zhang, B.1
Liu, X.X.2
He, J.R.3
Zhou, C.X.4
Guo, M.5
He, M.6
-
38
-
-
76649130555
-
Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship
-
Kim H, Huang W, Jiang X, Pennicooke B, Park PJ, Johnson MD. Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship. Proc Natl Acad Sci USA. 2010; 107: 2183-2188.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2183-2188
-
-
Kim, H.1
Huang, W.2
Jiang, X.3
Pennicooke, B.4
Park, P.J.5
Johnson, M.D.6
-
39
-
-
58149236959
-
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells
-
Viale A, De Franco F, Orleth A, Cambiaghi V, Giuliani V, Bossi D et al. Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells. Nature 2009; 457: 51-56.
-
(2009)
Nature
, vol.457
, pp. 51-56
-
-
Viale, A.1
De Franco, F.2
Orleth, A.3
Cambiaghi, V.4
Giuliani, V.5
Bossi, D.6
-
40
-
-
67349240823
-
A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of Acute Promyelocitic Leukemia cells
-
De Marchis ML, Ballarino M, Salvatori B, Puzzolo MC, Bozzoni I, Fatica A. A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of Acute Promyelocitic Leukemia cells. Leukemia 2009; 23: 856-862.
-
(2009)
Leukemia
, vol.23
, pp. 856-862
-
-
De Marchis, M.L.1
Ballarino, M.2
Salvatori, B.3
Puzzolo, M.C.4
Bozzoni, I.5
Fatica, A.6
-
41
-
-
78751640369
-
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation
-
Rosa A, Brivanlou AH. A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation. EMBO J 2011; 30: 237-248.
-
(2011)
EMBO J
, vol.30
, pp. 237-248
-
-
Rosa, A.1
Brivanlou, A.H.2
|