Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications

Cancer Research

Volumn 65, Issue 24, 2005, Pages 11367-11374

  Milne, Thomas A ^a   Martin, Mary Ellen ^a   Brock, Hugh W ^b   Slany, Robert K ^c   Hess, Jay L ^a,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HYBRID PROTEIN; METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; NUCLEAR PROTEIN;

ACETYLATION; ACUTE LEUKEMIA; ARTICLE; CHROMOSOME 11Q; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; HOX A9 GENE; HOX GENE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LEUKEMOGENESIS; MEIS1 GENE; METHYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; REAL TIME POLYMERASE CHAIN REACTION; TRANSACTIVATION; TRANSCRIPTION REGULATION; WILD TYPE;

DIMERIZATION; GENE EXPRESSION REGULATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; LYSINE; METHYLATION; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; TRANSCRIPTION, GENETIC;

EID: 29244433742     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-1041     Document Type: Article

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