-
1
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 1997;88:355-65.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
2
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A, Dixit VM. Death receptors: Signaling and modulation. Science 1998;281:1305-8.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
3
-
-
0035936797
-
The tnf and tnf receptor super family: Integrating mammalian biology
-
Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamily: Integrating mammalian biology. Cell 2001;104:487-501.
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
4
-
-
0033613143
-
Caspase activation: The induced-proximity model
-
Salvesen GS, Dixit VM. Caspase activation: The induced-proximity model. Proc Natl Acad Sci USA 1999;96:10964-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
5
-
-
2942746419
-
Caspase activation: Revisiting the induced proximity model
-
Shi Y. Caspase activation: Revisiting the induced proximity model. Cell 2004;117:855-8.
-
(2004)
Cell
, vol.117
, pp. 855-858
-
-
Shi, Y.1
-
6
-
-
22744436580
-
Engineering a dimeric caspase-9: A re-evaluation of the induced proximity model for caspase activation
-
Chao Y, Shiozaki EN, Srinivasula SM, Rigotti DJ, Fairman R, Shi Y. Engineering a dimeric caspase-9: A re-evaluation of the induced proximity model for caspase activation. PLoS Biol 2005;3[6]:e183.
-
(2005)
PLoS Biol
, vol.3
, Issue.6
, pp. e183
-
-
Chao, Y.1
Shiozaki, E.N.2
Srinivasula, S.M.3
Rigotti, D.J.4
Fairman, R.5
Shi, Y.6
-
8
-
-
17644378775
-
C-flipr, a new regulator of death receptor-induced apoptosis
-
Golks A, Brenner D, Fritsch C, Krammer PH, Lavrik IN. c-FLIPR, a new regulator of death receptor-induced apoptosis. J Biol Chem 2005;280:14507-13.
-
(2005)
J Biol Chem
, vol.280
, pp. 14507-14513
-
-
Golks, A.1
Brenner, D.2
Fritsch, C.3
Krammer, P.H.4
Lavrik, I.N.5
-
9
-
-
0037099678
-
C-flip(l) is a dual function regulator for caspase-8 activation and cd95-mediated apoptosis
-
Chang DW, Xing Z, Pan Y, et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J 2002;21:3704-14.
-
(2002)
EMBO J
, vol.21
, pp. 3704-3714
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
-
10
-
-
7344220967
-
Cell death attenuation by "usurpin, " a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex
-
Rasper DM, Vaillancourt JP, Hadano S, et al. Cell death attenuation by "Usurpin, " a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ 1998;5:271-88.
-
(1998)
Cell Death Differ
, vol.5
, pp. 271-288
-
-
Rasper, D.M.1
Vaillancourt, J.P.2
Hadano, S.3
-
11
-
-
0030800070
-
Inhibition of death receptor signals by cellular flip
-
Irmler M, Thome M, Hahne M, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-5.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
-
12
-
-
0035192884
-
Flice-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
Krueger A, Baumann S, Krammer PH, Kirchhoff S. FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis. Mol Cell Biol 2001;21:8247-54.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
13
-
-
0037160117
-
The long form of flip is an activator of caspase-8 at the fas death-inducing signaling complex
-
Micheau O, Thome M, Schneider P, et al. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 2002;277:45162-71.
-
(2002)
J Biol Chem
, vol.277
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
-
14
-
-
21244449877
-
Cellular flip long form augments caspase activity and death of t cells through heterodimerization with and activation of caspase-8
-
Dohrman A, Russell JQ, Cuenin S, Fortner K, Tschopp J, Budd RC. Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8. J Immunol 2005;175:311-8.
-
(2005)
J Immunol
, vol.175
, pp. 311-318
-
-
Dohrman, A.1
Russell, J.Q.2
Cuenin, S.3
Fortner, K.4
Tschopp, J.5
Budd, R.C.6
-
15
-
-
0033662341
-
Requirement for casper (C-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh WC, Itie A, Elia AJ, et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000;12:633-42.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
-
16
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh WC, Pompa JL, McCurrach ME, et al. FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998;279:1954-8.
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
-
17
-
-
0032555697
-
Cleavage of bid by caspase 8 mediates the mitochondrial damage in the FAS pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
18
-
-
0032555716
-
Bid, a bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
19
-
-
0035947776
-
Cathepsin b acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
-
Foghsgaard L, Wissing D, Mauch D, et al. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001;153:999-1010.
-
(2001)
J Cell Biol
, vol.153
, pp. 999-1010
-
-
Foghsgaard, L.1
Wissing, D.2
Mauch, D.3
-
20
-
-
0033756474
-
Cathepsin b contributes to tnf-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi ME, Deussing J, Miyoshi H, Bronk SF, Svingen PA, Peters C, Kaufmann SH, Gores GJ. Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 2000;106:1127-37.
-
(2000)
J Clin Invest
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
23
-
-
34347392130
-
Cflipl prevents trail-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis
-
Guicciardi ME, Bronk SF, Werneburg NW, Gores GJ. cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis. Am J Physiol Gastrointest Liver Physiol 2007;292:G1337-46.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
, pp. G1337-G1346
-
-
Guicciardi, M.E.1
Bronk, S.F.2
Werneburg, N.W.3
Gores, G.J.4
-
24
-
-
35348948380
-
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by BCL-2 proteins
-
Werneburg NW, Guicciardi ME, Bronk SF, Kaufmann SH, Gores GJ. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by BCL-2 proteins. J Biol Chem 2007;282:28960-70.
-
(2007)
J Biol Chem
, vol.282
, pp. 28960-28970
-
-
Werneburg, N.W.1
Guicciardi, M.E.2
Bronk, S.F.3
Kaufmann, S.H.4
Gores, G.J.5
-
25
-
-
33847051539
-
Rip1, a kinase on the crossroads of a cell's decision to live or die
-
Festjens N, Vanden Berghe T, Cornelis S, Vandenabeele P. RIP1, a kinase on the crossroads of a cell's decision to live or die. Cell Death Differ 2007;14:400-10.
-
(2007)
Cell Death Differ
, vol.14
, pp. 400-410
-
-
Festjens, N.1
Van Den Berghe, T.2
Cornelis, S.3
Van De Nabeele, P.4
-
26
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase rip as effector molecule
-
Holler N, Zaru R, Micheau O, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000;1:489-95.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
-
27
-
-
0028963667
-
Three functional soluble forms of the human apoptosis-inducing fas molecule are produced by alternative splicing
-
Cascino I, Fiucci G, Papoff G, Ruberti G. Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J Immunol 1995;154:2706-13.
-
(1995)
J Immunol
, vol.154
, pp. 2706-2713
-
-
Cascino, I.1
Fiucci, G.2
Papoff, G.3
Ruberti, G.4
-
28
-
-
0032500793
-
Cell surface trafficking of FAS: A rapid mechanism of p53-mediated apoptosis
-
Bennet M, MacDonald K, Chan S-W, Luzio JP, Simari R, Weissberg P. Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis. Science 1998;282:290-3.
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennet, M.1
MacDonald, K.2
Chan, S.-W.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
29
-
-
0033936183
-
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of fas
-
Sodeman T, Bronk SF, Roberts PJ, Miyoshi H, Gores GJ. Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am J Physiol Gastrointest Liver Physiol 2000;278:G992-G9.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.278
, pp. G992-G993
-
-
Sodeman, T.1
Bronk, S.F.2
Roberts, P.J.3
Miyoshi, H.4
Gores, G.J.5
-
30
-
-
0033953939
-
Colchicine protects mice from the lethal effect of an agonistic anti- fas antibody
-
Feng G, Kaplowitz N. Colchicine protects mice from the lethal effect of an agonistic anti- Fas antibody. J Clin Invest 2000;105:329-39.
-
(2000)
J Clin Invest
, vol.105
, pp. 329-339
-
-
Feng, G.1
Kaplowitz, N.2
-
31
-
-
0028835330
-
Cell surface sialylation plays a role in modulating sensitivity towards apo-1-mediated apoptotic cell death
-
Peter ME, Hellbardt S, Schwartz-Albiez R, et al. Cell surface sialylation plays a role in modulating sensitivity towards APO-1-mediated apoptotic cell death. Cell Death Differ 1995;2:163-71.
-
(1995)
Cell Death Differ
, vol.2
, pp. 163-171
-
-
Peter, M.E.1
Hellbardt, S.2
Schwartz-Albiez, R.3
-
32
-
-
33846247103
-
Palmitoylation of cd95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
-
Feig C, Tchikov V, Schutze S, Peter ME. Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling. EMBO J 2007;26:221-31.
-
(2007)
EMBO J
, vol.26
, pp. 221-231
-
-
Feig, C.1
Tchikov, V.2
Schutze, S.3
Peter, M.E.4
-
33
-
-
0033011889
-
Activation-dependent transcriptional regulation of the human FAS promoter requires NF-KAPPAB p50-p65 recruitment
-
Chan H, Bartos DP, Owen-Schaub LB. Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment. Mol Cell Biol 1999;19:2098-108.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2098-2108
-
-
Chan, H.1
Bartos, D.P.2
Owen-Schaub, L.B.3
-
34
-
-
0029935682
-
Involvement of the cd95 (APO-1/FAS) receptor/Ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 1996;2:574-80.
-
(1996)
Nat Med
, vol.2
, pp. 574-580
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
35
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the cd95 (apo-1/FAS) receptor/LIGAND system and involves activation of wild-type p53
-
Muller M, Strand S, Hug H, et al. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 1997;99:403-13.
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Muller, M.1
Strand, S.2
Hug, H.3
-
36
-
-
0031743648
-
P53 activates the cd95 (apo-1/FAS) gene in response to DNA damage by anticancer drugs
-
Muller M, Wilder S, Bannasch D, et al. p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 1998;188:2033-45.
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
-
37
-
-
0027145632
-
Molecular cloning and expression of the FAS ligand, a novel member of the tumor necrosis factor family
-
Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169-78.
-
(1993)
Cell
, vol.75
, pp. 1169-1178
-
-
Suda, T.1
Takahashi, T.2
Golstein, P.3
Nagata, S.4
-
38
-
-
0028932731
-
The ctl's kiss of death
-
Berke G. The CTL's kiss of death. Cell 1995;81:9-12.
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
39
-
-
0028110928
-
Fas and perforin pathways as major mechanisms of t-cell-mediated cytotoxicity
-
Kagi D, Vignaux F, Ledermann B, et al. Fas and perforin pathways as major mechanisms of T-cell-mediated cytotoxicity. Science 1994;265:528-30.
-
(1994)
Science
, vol.265
, pp. 528-530
-
-
Kagi, D.1
Vignaux, F.2
Ledermann, B.3
-
40
-
-
0027937745
-
Cytolytic t-cell cytotoxicity is mediated through perforin and fas lytic pathyways
-
Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathyways. Nature 1994;370:650-2.
-
(1994)
Nature
, vol.370
, pp. 650-652
-
-
Lowin, B.1
Hahne, M.2
Mattmann, C.3
Tschopp, J.4
-
41
-
-
0032550366
-
Conversion of membrane-bound FAS(cd95) ligand to its soluble form is associated with down regulation of its proapoptotic activity and loss of liver toxicity
-
Schneider P, Holler N, Bodmer JL, et al. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with down regulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 1998;187:1205-13.
-
(1998)
J Exp Med
, vol.187
, pp. 1205-1213
-
-
Schneider, P.1
Holler, N.2
Bodmer, J.L.3
-
42
-
-
13344268993
-
Fas ligand in human serum
-
Tanaka M, Suda T, Haze K, et al. Fas ligand in human serum. Nat Med 1996;2:317-22.
-
(1996)
Nat Med
, vol.2
, pp. 317-322
-
-
Tanaka, M.1
Suda, T.2
Haze, K.3
-
43
-
-
0028919473
-
Expression of the functional soluble form of human FAS ligand in activated lymphocytes
-
Tanaka M, Suda T, Takahashi T, Nagata S. Expression of the functional soluble form of human Fas ligand in activated lymphocytes. EMBO J 1995;14:1129-35.
-
(1995)
EMBO J
, vol.14
, pp. 1129-1135
-
-
Tanaka, M.1
Suda, T.2
Takahashi, T.3
Nagata, S.4
-
44
-
-
0034850864
-
The membrane-bound but not the soluble form of human FAS ligand is responsible for its inflammatory activity
-
Shudo K, Kinoshita K, Imamura R, et al. The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity. Eur J Immunol 2001;31:2504-11.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2504-2511
-
-
Shudo, K.1
Kinoshita, K.2
Imamura, R.3
-
45
-
-
0031452949
-
Membrane fas ligand kills human peripheral blood t lymphocytes, and soluble fas ligand blocks the killing
-
Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 1997;186:2045-50.
-
(1997)
J Exp Med
, vol.186
, pp. 2045-2050
-
-
Suda, T.1
Hashimoto, H.2
Tanaka, M.3
Ochi, T.4
Nagata, S.5
-
46
-
-
0034600068
-
Opposing effects of trans membrane and soluble fas ligand expression on inflammation and tumor cell survival
-
Hohlbaum AM, Moe S, Marshak-Rothstein A. Opposing effects of trans membrane and soluble Fas ligand expression on inflammation and tumor cell survival. J Exp Med 2000;19:1209-20.
-
(2000)
J Exp Med
, vol.19
, pp. 1209-1220
-
-
Hohlbaum, A.M.1
Moe, S.2
Marshak-Rothstein, A.3
-
47
-
-
0032969285
-
Tumor necrosis factor receptor and fas signaling mechanisms
-
Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol 1999;17:331-67.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
48
-
-
0035824635
-
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
-
Kischkel FC, Lawrence DA, Tinel A, et al. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 2001;276:46639-46.
-
(2001)
J Biol Chem
, vol.276
, pp. 46639-46646
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Tinel, A.3
-
49
-
-
0035923653
-
Caspase-10 is an initiator caspase in death receptor signaling
-
Wang J, Chun HJ, Wong W, Spencer DM, Lenardo MJ. Caspase-10 is an initiator caspase in death receptor signaling. Proc Natl Acad Sci USA 2001;98:13884-8.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13884-13888
-
-
Wang, J.1
Chun, H.J.2
Wong, W.3
Spencer, D.M.4
Lenardo, M.J.5
-
50
-
-
16844381848
-
The extracellular domains of fasl and fas are sufficient for the formation of supra molecular fasl-fas clusters of high stability
-
Henkler F, Behrle E, Dennehy KM, et al. The extracellular domains of FasL and Fas are sufficient for the formation of supra molecular FasL-Fas clusters of high stability. J Cell Biol 2005;168:1087-98.
-
(2005)
J Cell Biol
, vol.168
, pp. 1087-1098
-
-
Henkler, F.1
Behrle, E.2
Dennehy, K.M.3
-
51
-
-
9444268061
-
Spots: Signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane
-
Siegel RM, Muppidi JR, Sarker M, et al. SPOTS: Signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. J Cell Biol 2004;167:735-44.
-
(2004)
J Cell Biol
, vol.167
, pp. 735-744
-
-
Siegel, R.M.1
Muppidi, J.R.2
Sarker, M.3
-
52
-
-
0036133127
-
Molecular ordering of the initial signaling events of CD95
-
Algeciras-Schimnich A, Shen L, Barnhart BC, Murmann AE, Burkhardt JK, Peter ME. Molecular ordering of the initial signaling events of CD95. Mol Cell Biol 2002;22:207-20.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 207-220
-
-
Algeciras-Schimnich, A.1
Shen, L.2
Barnhart, B.C.3
Murmann, A.E.4
Burkhardt, J.K.5
Peter, M.E.6
-
53
-
-
3442895056
-
Cd95 death-inducing signaling complex formation and internalization occur in lipid rafts of type i and type ii cells
-
Eramo A, Sargiacomo M, Ricci-Vitiani L, et al. CD95 death-inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells. Eur J Immunol 2004;34:1930-40.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1930-1940
-
-
Eramo, A.1
Sargiacomo, M.2
Ricci-Vitiani, L.3
-
54
-
-
30744459357
-
Modulation of FAS-mediated apoptosis by lipid rafts in t lymphocytes
-
Legembre P, Daburon S, Moreau P, Moreau JF, Taupin JL. Modulation of Fas-mediated apoptosis by lipid rafts in T lymphocytes. J Immunol 2006;176:716-20.
-
(2006)
J Immunol
, vol.176
, pp. 716-720
-
-
Legembre, P.1
Daburon, S.2
Moreau, P.3
Moreau, J.F.4
Taupin, J.L.5
-
55
-
-
33644858084
-
The role of receptor internalization in cd95 signaling
-
Lee KH, Feig C, Tchikov V, et al. The role of receptor internalization in CD95 signaling. EMBO J 2006;25:1009-23.
-
(2006)
EMBO J
, vol.25
, pp. 1009-1023
-
-
Lee, K.H.1
Feig, C.2
Tchikov, V.3
-
57
-
-
0038198615
-
Actin dependent cd95 internalization is specific for type i cells
-
Algeciras-Schimnich A, Peter ME. Actin dependent CD95 internalization is specific for Type I cells. FEBS Lett 2003;546:185-8.
-
(2003)
FEBS Lett
, vol.546
, pp. 185-188
-
-
Algeciras-Schimnich, A.1
Peter, M.E.2
-
58
-
-
0029950290
-
BCL-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin SA, Zamzami N, Castedo M, et al. BCL-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996;184:1331-41.
-
(1996)
J Exp Med
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
-
59
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating iap inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
60
-
-
0034616942
-
Identification of diablo, a mammalian protein that promotes apoptosis by binding to and antagonizing iap proteins
-
Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000;102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
61
-
-
0028223847
-
Generalized lympho proliferative disease in mice, caused by a point mutation in the fas ligand
-
Takahashi T, Tanaka M, Brannan CI, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994;76:969-76.
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
-
62
-
-
0026568919
-
Lympho proliferation disorder in mice explained by defects in FAS antigen that mediates apoptosis
-
Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lympho proliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992;356:314-7.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
63
-
-
0025875259
-
Lpr and gld: Single gene models of systemic autoimmunity and lympho proliferative disease
-
Cohen PL, Eisenberg RA. Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1991;9:243-69.
-
(1991)
Annu Rev Immunol
, vol.9
, pp. 243-269
-
-
Cohen, P.L.1
Eisenberg, R.A.2
-
64
-
-
33645784245
-
Genetic disorders of programmed cell death in the immune system
-
Bidere N, Su HC, Lenardo MJ. Genetic disorders of programmed cell death in the immune system. Annu Rev Immunol 2006;24:321-52.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 321-352
-
-
Bidere, N.1
Su, H.C.2
Lenardo, M.J.3
-
65
-
-
0034641898
-
Cd95's deadly mission in the immune system
-
Krammer PH. CD95's deadly mission in the immune system. Nature 2000;407:789-95.
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
66
-
-
0028927607
-
The fas death factor
-
Nagata S, Golstein P. The Fas death factor. Science 1995;267:1449-56.
-
(1995)
Science
, vol.267
, pp. 1449-1456
-
-
Nagata, S.1
Golstein, P.2
-
67
-
-
0036377840
-
The biological role of the FAS/FASL system during tumor formation and progression
-
Reichmann E. The biological role of the Fas/FasL system during tumor formation and progression. Semin Cancer Biol 2002;12:309-15.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 309-315
-
-
Reichmann, E.1
-
69
-
-
10544232277
-
Melanoma cell expression of FAS(APO-1/CD95) ligand: Implications for tumor immune escape
-
Hahne M, Rimoldi D, Schroter M, et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape. Science 1996;274:1363-6.
-
(1996)
Science
, vol.274
, pp. 1363-1366
-
-
Hahne, M.1
Rimoldi, D.2
Schroter, M.3
-
70
-
-
16144363507
-
Lymphocyte apoptosis induced by cd95 (apo-1/FAS) ligand-expressing tumor cells-a mechanism of immune evasion?
-
Strand S, Hofmann WJ, Hug H, et al. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells-A mechanism of immune evasion? Nat Med 1996;2:1361-6.
-
(1996)
Nat Med
, vol.2
, pp. 1361-1366
-
-
Strand, S.1
Hofmann, W.J.2
Hug, H.3
-
73
-
-
10044232636
-
Induction of apoptosis and activation of NF kappa b by cd95 require different signalling thresholds
-
Legembre P, Barnhart BC, Zheng L, et al. Induction of apoptosis and activation of NF kappa B by CD95 require different signalling thresholds. EMBO Rep 2004;5:1084-9.
-
(2004)
EMBO Rep
, vol.5
, pp. 1084-1089
-
-
Legembre, P.1
Barnhart, B.C.2
Zheng, L.3
-
74
-
-
0142117313
-
The BCL-2 family: Roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM. The BCL-2 family: Roles in cell survival and oncogenesis. Oncogene 2003;22:8590-607.
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
75
-
-
0033523670
-
Immune escape of tumors in vivo by expression of cellular flice-inhibitory protein
-
Medema JP, de Jong J, van Hall T, Melief CJ, Offringa R. Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein. J Exp Med 1999;190:1033-8.
-
(1999)
J Exp Med
, vol.190
, pp. 1033-1038
-
-
Medema, J.P.1
De Jong, J.2
Van Hall, T.3
Melief, C.J.4
Offringa, R.5
-
76
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of mycn
-
Teitz T, Wei T, Valentine MB, et al. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 2000;6:529-35.
-
(2000)
Nat Med
, vol.6
, pp. 529-535
-
-
Teitz, T.1
Wei, T.2
Valentine, M.B.3
-
77
-
-
4143108125
-
Cd95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells
-
Barnhart BC, Legembre P, Pietras E, Bubici C, Franzoso G, Peter ME. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO J 2004;23:3175-85.
-
(2004)
EMBO J
, vol.23
, pp. 3175-3185
-
-
Barnhart, B.C.1
Legembre, P.2
Pietras, E.3
Bubici, C.4
Franzoso, G.5
Peter, M.E.6
-
78
-
-
0027291205
-
Lethal effect of the anti-fas antibody in mice
-
Ogasawara J, Watanabe-Fukunaga R, Adachi M, et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993;364:806-9.
-
(1993)
Nature
, vol.364
, pp. 806-809
-
-
Ogasawara, J.1
Watanabe-Fukunaga, R.2
Adachi, M.3
-
79
-
-
0027297663
-
Mice deficient for the 55 KD tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to l. Monocytogenes infection
-
Pfeffer K, Matsuyama T, Kundig TM, et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993;73:457-67.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
-
80
-
-
0035914945
-
Impaired c-jun amino terminal kinase activity and t cell differentiation in death receptor 6-deficient mice
-
Zhao H, Yan M, Wang H, Erickson S, Grewal IS, Dixit VM. Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice. J Exp Med 2001;194:1441-8.
-
(2001)
J Exp Med
, vol.194
, pp. 1441-1448
-
-
Zhao, H.1
Yan, M.2
Wang, H.3
Erickson, S.4
Grewal, I.S.5
Dixit, V.M.6
-
82
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumor necrosis factor a from cells
-
Black RA, Rauch CT, Kozlosky CJ, et al. A metalloproteinase disintegrin that releases tumor necrosis factor a from cells. Nature 1997;385:729-33.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
-
83
-
-
0041853690
-
Induction of TNF receptor-1-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. Induction of TNF receptor-1-mediated apoptosis via two sequential signaling complexes. Cell 2003;114:181-90.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
84
-
-
0035889252
-
Induction of gadd45b by NF-KB down regulates pro-apoptotic jnk signalling
-
De Smaele E, Zazzeroni F, Papa S, et al. Induction of gadd45b by NF-kB down regulates pro-apoptotic JNK signalling. Nature 2001;414:308-13.
-
(2001)
Nature
, vol.414
, pp. 308-313
-
-
De Smaele, E.1
Zazzeroni, F.2
Papa, S.3
-
85
-
-
0035891320
-
Inhibition of JNK activation through NF-KB target genes
-
Tang G, Minemoto Y, Dibling B, et al. Inhibition of JNK activation through NF-kB target genes. Nature 2001;414:313-7.
-
(2001)
Nature
, vol.414
, pp. 313-317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
-
86
-
-
0035122689
-
Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling
-
Wajant H, Scheurich P. Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling. Int J Biochem Cell Biol 2001;33:19-32.
-
(2001)
Int J Biochem Cell Biol
, vol.33
, pp. 19-32
-
-
Wajant, H.1
Scheurich, P.2
-
87
-
-
0032508414
-
NF-KB anti apoptosis: Induction of TRAF 1 and TRAF 2 and c-iap1 and c-iap2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS. NF-kB antiapoptosis: Induction of TRAF 1 and TRAF 2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998;281:1680-3.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin, A.S.5
-
88
-
-
0034282432
-
The inhibitor of apoptosis, ciap2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspase-3 and -7
-
Huang H, Joazeiro CA, Bonfoco E, Kamada S, Leverson JD, Hunter T. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspase-3 and -7. J Biol Chem 2000;275:26661-4.
-
(2000)
J Biol Chem
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfoco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
89
-
-
33744951304
-
Ubiquitination of rip is required for tumor necrosis factor alpha-induced nf-kappab activation
-
Li H, Kobayashi M, Blonska M, You Y, Lin X. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem 2006;281:13636-43.
-
(2006)
J Biol Chem
, vol.281
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
90
-
-
0038742813
-
Recruitment of TNF receptor 1 to lipid rafts is essential for TNF alpha-mediated nf-kappab activation
-
Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity 2003;18:655-64.
-
(2003)
Immunity
, vol.18
, pp. 655-664
-
-
Legler, D.F.1
Micheau, O.2
Doucey, M.A.3
Tschopp, J.4
Bron, C.5
-
91
-
-
33750593637
-
Inhibition of TNF receptor 1 internalization by adenovirus 14.7kas a novel immune escape mechanism
-
Schneider-Brachert W, Tchikov V, Merkel O, et al. Inhibition of TNF receptor 1 internalization by adenovirus 14.7Kas a novel immune escape mechanism. J Clin Invest 2006;116:2901-13.
-
(2006)
J Clin Invest
, vol.116
, pp. 2901-2913
-
-
Schneider-Brachert, W.1
Tchikov, V.2
Merkel, O.3
-
92
-
-
0031021356
-
RAIDD is a new "death" adaptor molecule
-
Duan H, Dixit VM. RAIDD is a new "death" adaptor molecule. Nature 1997;385:86-9.
-
(1997)
Nature
, vol.385
, pp. 86-89
-
-
Duan, H.1
Dixit, V.M.2
-
93
-
-
0030990177
-
Bile duct and portal and central veins are major producers of tumor necrosis factor alpha in regenerating rat liver
-
Loffreda S, Rai R, Yang SQ, Lin HZ, Diehl AM. Bile duct and portal and central veins are major producers of tumor necrosis factor alpha in regenerating rat liver. Gastroenterology 1997;112:2089-98.
-
(1997)
Gastroenterology
, vol.112
, pp. 2089-2098
-
-
Loffreda, S.1
Rai, R.2
Yang, S.Q.3
Lin, H.Z.4
Diehl, A.M.5
-
94
-
-
0031028140
-
Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type i tumor necrosis receptor
-
Yamada Y, Kirillova I, Peschon JJ, Fausto N. Initiation of liver growth by tumor necrosis factor: Deficient liver regeneration in mice lacking type I tumor necrosis receptor. Proc Natl Acad Sci USA 1997;94:1441-6.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1441-1446
-
-
Yamada, Y.1
Kirillova, I.2
Peschon, J.J.3
Fausto, N.4
-
95
-
-
0032835529
-
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice
-
Yin M, Wheeler MD, Kono H, et al. Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology 1999;117:942-52.
-
(1999)
Gastroenterology
, vol.117
, pp. 942-952
-
-
Yin, M.1
Wheeler, M.D.2
Kono, H.3
-
96
-
-
0025250037
-
Spontaneous production of tumor necrosis factor a and interleukin b during interferon treatment of chronic hbv infection
-
Daniels H, Meager A, Goka J, Eddlestone ALWF, Alexander GJM, Williams R. Spontaneous production of tumor necrosis factor a and interleukin b during interferon treatment of chronic HBV infection. Lancet 1990;335:875-7.
-
(1990)
Lancet
, vol.335
, pp. 875-877
-
-
Daniels, H.1
Meager, A.2
Goka, J.3
Eddlestone, A.L.W.F.4
Alexander, G.J.M.5
Williams, R.6
-
97
-
-
0028979703
-
Tumor necrosis factor-alpha is required in the protective immune response against mycobacterium tuberculosis in mice
-
Flynn JL, Goldstein MM, Chan J, et al. Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 1995;2:561-72.
-
(1995)
Immunity
, vol.2
, pp. 561-572
-
-
Flynn, J.L.1
Goldstein, M.M.2
Chan, J.3
-
98
-
-
0000682810
-
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling
-
Le Hir M, Bluethmann H, Kosco-Vilbois MH, et al. Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling. J Exp Med 1996;183:2367-72.
-
(1996)
J Exp Med
, vol.183
, pp. 2367-2372
-
-
Le, H.M.1
Bluethmann, H.2
Kosco-Vilbois, M.H.3
-
99
-
-
0345609037
-
Characterization of tumor necrosis fact or deficient mice
-
Marino MW, Dunn A, Grail D, et al. Characterization of tumor necrosis factordeficient mice. Proc Natl Acad Sci USA 1997;94:8093-8.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8093-8098
-
-
Marino, M.W.1
Dunn, A.2
Grail, D.3
-
100
-
-
0034095570
-
Tnfrsf1a mutations and autoinflammatory syndromes
-
Galon J, Aksentijevich I, McDermott MF, O'Shea JJ, Kastner DL. TNFRSF1A mutations and autoinflammatory syndromes. Curr Opin Immunol 2000;12:479-86.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 479-486
-
-
Galon, J.1
Aksentijevich, I.2
McDermott, M.F.3
O'Shea, J.J.4
Kastner, D.L.5
-
101
-
-
0033738779
-
Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases
-
Illei GG, Lipsky PE. Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases. Curr Opin Immunol 2000;12:712-8.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 712-718
-
-
Illei, G.G.1
Lipsky, P.E.2
-
102
-
-
0035056003
-
Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned?
-
Feldmann M, Maini RN. Anti-TNF alpha therapy of rheumatoid arthritis: What have we learned? Annu Rev Immunol 2001;19:163-96.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 163-196
-
-
Feldmann, M.1
Maini, R.N.2
-
103
-
-
0037319273
-
Overview of the use of the anti-TNF agent in fliximab in chronic inflammatory diseases
-
Braun J, Sieper J. Overview of the use of the anti-TNF agent in fliximab in chronic inflammatory diseases. Expert Opin Biol Ther 2003;3:141-68.
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 141-168
-
-
Braun, J.1
Sieper, J.2
-
104
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for trail
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997;277:815-8.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
105
-
-
0030996297
-
The receptor for the cytotoxic ligand trail
-
Pan G, O'Rourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997;276:111-3.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
-
106
-
-
0031472042
-
Cell death: Trail and its receptors
-
Golstein P. Cell death: TRAIL and its receptors. Curr Biol 1997;7:R750-R3.
-
(1997)
Curr Biol
, vol.7
, pp. R750-R753
-
-
Golstein, P.1
-
107
-
-
0030869432
-
Cloning and characterization of trail-r3, a novel member of the emerging trail receptor family
-
Degli-Esposti MA, Smolak PJ, Walczak H, et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 1997;186:1165-70.
-
(1997)
J Exp Med
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
-
108
-
-
0031414749
-
The novel receptor trail-r4 induces NF-kappab and protects against trail-mediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 1997;7:813-20.
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
109
-
-
29144496895
-
Preligand assembly domain-mediated ligandin dependent association between trail receptor 4 (tr4) and tr2 regulates trail induced apoptosis
-
Clancy L, Mruk K, Archer K, et al. Preligand assembly domain-mediated ligandin dependent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL induced apoptosis. Proc Natl Acad Sci USA 2005;102:18099-104.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18099-18104
-
-
Clancy, L.1
Mruk, K.2
Archer, K.3
-
110
-
-
20344396647
-
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL
-
Riccioni R, Pasquini L, Mariani G, et al. TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL. Haematologica 2005;90:612-24.
-
(2005)
Haematologica
, vol.90
, pp. 612-624
-
-
Riccioni, R.1
Pasquini, L.2
Mariani, G.3
-
111
-
-
33749164762
-
Differential inhibition of trail-mediated dr5-disc formation by decoy receptors 1 and 2
-
Merino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol 2006;26:7046-55.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7046-7055
-
-
Merino, D.1
Lalaoui, N.2
Morizot, A.3
Schneider, P.4
Solary, E.5
Micheau, O.6
-
112
-
-
0034725664
-
Temperature-sensitive differential affinity of trail for its receptors. Dr5 is the highest affinity receptor
-
Truneh A, Sharma S, Silverman C, et al. Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor. J Biol Chem 2000;275:23319-25.
-
(2000)
J Biol Chem
, vol.275
, pp. 23319-23325
-
-
Truneh, A.1
Sharma, S.2
Silverman, C.3
-
113
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995;3:673-82.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
-
114
-
-
17544367410
-
Induction of apoptosis by apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996;271:12687-90.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
115
-
-
0347364696
-
NK cell trail eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy
-
Hayakawa Y, Screpanti V, Yagita H, et al. NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy. J Immunol 2004;172:123-9.
-
(2004)
J Immunol
, vol.172
, pp. 123-129
-
-
Hayakawa, Y.1
Screpanti, V.2
Yagita, H.3
-
116
-
-
14544288632
-
Cd4+ t-cell help controls cd8+ t-cell memory via trail-mediated activation-induced cell death
-
Janssen EM, Droin NM, Lemmens EE, et al. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005;434:88-93.
-
(2005)
Nature
, vol.434
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
-
117
-
-
0037240850
-
Nature's trail-on a path to cancer immunotherapy
-
Smyth MJ, Takeda K, Hayakawa Y, Peschon JJ, van den Brink MR, Yagita H. Nature's TRAIL-On a path to cancer immunotherapy. Immunity 2003;18:1-6.
-
(2003)
Immunity
, vol.18
, pp. 1-6
-
-
Smyth, M.J.1
Takeda, K.2
Hayakawa, Y.3
Peschon, J.J.4
Van Den Brink, M.R.5
Yagita, H.6
-
118
-
-
0031905817
-
Differential regulation of TRAIL and CD95 LIGAND in transformed cells of the t and b lymphocyte lineage
-
Mariani SM, Krammer PH. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur J Immunol 1998;28:973-82.
-
(1998)
Eur J Immunol
, vol.28
, pp. 973-982
-
-
Mariani, S.M.1
Krammer, P.H.2
-
119
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999;104:155-62.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
-
120
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant apo2l/trail versions
-
Lawrence D, Shahrokh Z, Marsters S, et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 2001;7:383-5.
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
-
121
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, et al. Tumoricidal activity of tumor necrosis factor related apoptosis-inducing ligand in vivo. Nat Med 1999;5:157-63.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
-
122
-
-
0034682802
-
Fadd is required for dr4- and dr5- mediated apoptosis: Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
-
Kuang AA, Diehl GE, Zhang J, Winoto A. FADD is required for DR4- and DR5- mediated apoptosis: Lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 2000;275:25065-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 25065-25068
-
-
Kuang, A.A.1
Diehl, G.E.2
Zhang, J.3
Winoto, A.4
-
123
-
-
0033824918
-
The trail DIS cussion: It is FADD and caspase-8!
-
Peter ME. The TRAIL DIS Cussion: It is FADD and caspase-8! Cell Death Diff 2000;7:759-60.
-
(2000)
Cell Death Diff
, vol.7
, pp. 759-760
-
-
Peter, M.E.1
-
124
-
-
34250331231
-
Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (trail)-induced apoptosis
-
Kohlhaas SL, Craxton A, Sun XM, Pinkoski MJ, Cohen GM. Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J Biol Chem 2007;282:12831-41.
-
(2007)
J Biol Chem
, vol.282
, pp. 12831-12841
-
-
Kohlhaas, S.L.1
Craxton, A.2
Sun, X.M.3
Pinkoski, M.J.4
Cohen, G.M.5
-
125
-
-
0034630161
-
The cd95 (apo-1/FAS) and the trail (apo-2l) apoptosis systems
-
Walczak H, Krammer PH. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 2000;256:58-66.
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
126
-
-
34948894931
-
Death-receptor o-glycosylation controls tumor-cell sensitivity to the pro apoptotic ligand apo2l/trail
-
Wagner KW, Punnoose EA, Januario T, et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the pro apoptotic ligand Apo2L/TRAIL. Nat Med 2007;13:1070-7.
-
(2007)
Nat Med
, vol.13
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
-
128
-
-
0032697485
-
Tumor necrosis factor-related apoptosis-inducing ligand receptors signal nf-kappab and JNK activation and apoptosis through distinct pathways
-
Hu WH, Johnson H, Shu HB. Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. J Biol Chem 1999;274:30603-10.
-
(1999)
J Biol Chem
, vol.274
, pp. 30603-30610
-
-
Hu, W.H.1
Johnson, H.2
Shu, H.B.3
-
129
-
-
28844441555
-
Molecular determinants of kinase pathway activation by apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
-
Varfolomeev E, Maecker H, Sharp D, et al. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J Biol Chem 2005;280:40599-608.
-
(2005)
J Biol Chem
, vol.280
, pp. 40599-40608
-
-
Varfolomeev, E.1
Maecker, H.2
Sharp, D.3
-
130
-
-
0037105386
-
Mitogenactivated protein kinase/extracellular signal-regulated kinase signaling in activated t cells abrogates trail-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8
-
Soderstrom TS, Poukkula M, Holmstrom TH, Heiskanen KM, Eriksson JE. Mitogenactivated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8. J Immunol 2002;169:2851-60.
-
(2002)
J Immunol
, vol.169
, pp. 2851-2860
-
-
Soderstrom, T.S.1
Poukkula, M.2
Holmstrom, T.H.3
Heiskanen, K.M.4
Eriksson, J.E.5
-
131
-
-
0035844129
-
Mapk/erk overrides the apoptotic signaling from fas, tnf, and trail receptors
-
Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J Biol Chem 2001;276:16484-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 16484-16490
-
-
Tran, S.E.1
Holmstrom, T.H.2
Ahonen, M.3
Kahari, V.M.4
Eriksson, J.E.5
-
132
-
-
33750813868
-
Acquired trail resistance in human breast cancer cells are caused by the sustained cflip(l) and xiap protein levels and erk activation
-
Lee TJ, Lee JT, Park JW, Kwon TK. Acquired TRAIL resistance in human breast cancer cells are caused by the sustained cFLIP(L) and XIAP protein levels and ERK activation. Biochem Biophys Res Commun 2006;351:1024-30.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 1024-1030
-
-
Lee, T.J.1
Lee, J.T.2
Park, J.W.3
Kwon, T.K.4
-
134
-
-
33845221022
-
Trail promotes metastasis of human pancreatic ductal adenocarcinoma
-
Trauzold A, Siegmund D, Schniewind B, et al. TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma. Oncogene 2006;25:7434-9.
-
(2006)
Oncogene
, vol.25
, pp. 7434-7439
-
-
Trauzold, A.1
Siegmund, D.2
Schniewind, B.3
-
135
-
-
0042844783
-
Trail-induced apoptosis and gene induction in hacat keratinocytes: Differential contribution of trail receptors 1 and 2
-
Leverkus M, Sprick MR, Wachter T, et al. TRAIL-induced apoptosis and gene induction in HaCaT keratinocytes: Differential contribution of TRAIL receptors 1 and 2. J Invest Dermatol 2003;121:149-55.
-
(2003)
J Invest Dermatol
, vol.121
, pp. 149-155
-
-
Leverkus, M.1
Sprick, M.R.2
Wachter, T.3
-
136
-
-
0035137696
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
-
Takeda K, Hayakawa Y, Smyth MJ, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 2001;7:94-100.
-
(2001)
Nat Med
, vol.7
, pp. 94-100
-
-
Takeda, K.1
Hayakawa, Y.2
Smyth, M.J.3
-
137
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in tnf-related apoptosis-inducing ligand-deficient mice
-
Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol 2002;168:1356-61.
-
(2002)
J Immunol
, vol.168
, pp. 1356-1361
-
-
Cretney, E.1
Takeda, K.2
Yagita, H.3
Glaccum, M.4
Peschon, J.J.5
Smyth, M.J.6
-
138
-
-
0036687185
-
Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, trail/apo2l, using trail/apo2l gene-deficient mice
-
Sedger LM, Glaccum MB, Schuh JC, et al. Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice. Eur J Immunol 2002;32:2246-54.
-
(2002)
Eur J Immunol
, vol.32
, pp. 2246-2254
-
-
Sedger, L.M.1
Glaccum, M.B.2
Schuh, J.C.3
-
139
-
-
38149139518
-
Trail-r deficiency in mice promotes susceptibility to chronic inflammation and tum origenesis
-
Finnberg N, Klein-Szanto AJ, El-Deiry WS. TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tum origenesis. J Clin Invest 2008;118:111-23.
-
(2008)
J Clin Invest
, vol.118
, pp. 111-123
-
-
Finnberg, N.1
Klein-Szanto, A.J.2
El-Deiry, W.S.3
-
140
-
-
38149122326
-
Trail-r deficiency in mice enhances lymph node metastasis without affecting primary tumor development
-
Grosse-Wilde A, Voloshanenko O, Bailey SL, et al. TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development. J Clin Invest 2008;118:100-10.
-
(2008)
J Clin Invest
, vol.118
, pp. 100-110
-
-
Grosse-Wilde, A.1
Voloshanenko, O.2
Bailey, S.L.3
-
141
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 2000;6:564-7.
-
(2000)
Nat Med
, vol.6
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
-
142
-
-
0742272016
-
Human normal hepatocytes are susceptible to apoptosis signal mediated by both trail-r1 and trail-r2
-
Mori E, Thomas M, Motoki K, et al. Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2. Cell Death Differ 2004;11:203-7.
-
(2004)
Cell Death Differ
, vol.11
, pp. 203-207
-
-
Mori, E.1
Thomas, M.2
Motoki, K.3
-
144
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of trail either alone or in combination with chemotherapeutic drugs
-
Ganten TM, Koschny R, Sykora J, et al. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 2006;12:2640-6.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
-
145
-
-
34248187996
-
Phase i pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1
-
Tolcher AW, Mita M, Meropol NJ, et al. Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1. J Clin Oncol 2007;25:1390-5.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1390-1395
-
-
Tolcher, A.W.1
Mita, M.2
Meropol, N.J.3
-
146
-
-
35948952826
-
Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
-
Plummer R, Attard G, Pacey S, et al. Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers. Clin Cancer Res 2007;13:6187-94.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6187-6194
-
-
Plummer, R.1
Attard, G.2
Pacey, S.3
-
147
-
-
34248190642
-
On the trail toward death receptor-based cancer therapeutics
-
Gajewski TF. On the TRAIL toward death receptor-based cancer therapeutics. J Clin Oncol 2007;25:1305-7.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1305-1307
-
-
Gajewski, T.F.1
-
148
-
-
10544236916
-
Signal transduction by dr3, a death domain-containing receptor related to tnfr-1 and cd95
-
Chinnaiyan AM, O'Rourke K, Yu GL, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996;274:990-2.
-
(1996)
Science
, vol.274
, pp. 990-992
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Yu, G.L.3
-
149
-
-
0030896087
-
Tramps, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and fas (apo-1/cd95)
-
Bodmer JL, Burns K, Schneider P, et al. TRAMPS, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95). Immunity 1997;6:79-88.
-
(1997)
Immunity
, vol.6
, pp. 79-88
-
-
Bodmer, J.L.1
Burns, K.2
Schneider, P.3
-
150
-
-
0029969717
-
A death-domain-containing receptor that mediates apoptosis
-
Kitson J, Raven T, Jiang YP, et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996;384:372-5.
-
(1996)
Nature
, vol.384
, pp. 372-375
-
-
Kitson, J.1
Raven, T.2
Jiang, Y.P.3
-
151
-
-
0030466894
-
Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and nf-kb
-
Marsters SA, Sheridan JP, Donahue CJ, et al. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kB. Curr Biol 1996;6:1669-76.
-
(1996)
Curr Biol
, vol.6
, pp. 1669-1676
-
-
Marsters, S.A.1
Sheridan, J.P.2
Donahue, C.J.3
-
152
-
-
37249091646
-
Tumor necrosis factor family receptors regulating bone turnover: New observations in osteoblastic and osteoclastic cell lines
-
Robinson LJ, Borysenko CW, Blair HC. Tumor necrosis factor family receptors regulating bone turnover: New observations in osteoblastic and osteoclastic cell lines. Ann NY Acad Sci 2007;1116:432-43.
-
(2007)
Ann NY Acad Sci
, vol.1116
, pp. 432-443
-
-
Robinson, L.J.1
Borysenko, C.W.2
Blair, H.C.3
-
153
-
-
0032559998
-
Identification of a ligand for the death-domain-containing receptor apo3
-
Marsters SA, Sheridan JP, Pitti RM, Brush J, Goddard AD, Ashkenazi A. Identification of a ligand for the death-domain-containing receptor Apo3. Curr Biol 1998;8:525-8.
-
(1998)
Curr Biol
, vol.8
, pp. 525-528
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Brush, J.4
Goddard, A.D.5
Ashkenazi, A.6
-
154
-
-
0035027854
-
Dr3 regulates negative selection during thymocyte development
-
Wang ECY, Thern A, Denzel A, Kitson J, Farrow SN, Owen MJ. DR3 regulates negative selection during thymocyte development. Mol Cell Biol 2001;21:3451-61.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3451-3461
-
-
Wang, E.C.Y.1
Thern, A.2
Denzel, A.3
Kitson, J.4
Farrow, S.N.5
Owen, M.J.6
-
155
-
-
18344385475
-
Tl1a is a tnf-like ligand for dr3 and tr6/dcr3 and functions as a t cell costimulator
-
Migone TS, Zhang J, Luo X, et al. TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity 2002;16:479-92.
-
(2002)
Immunity
, vol.16
, pp. 479-492
-
-
Migone, T.S.1
Zhang, J.2
Luo, X.3
-
156
-
-
0032563275
-
Identification and functional characterization of dr6, a novel death domain-containing tnf receptor
-
Pan G, Bauer JH, Haridas V, et al. Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett 1998;431:351-6.
-
(1998)
FEBS Lett
, vol.431
, pp. 351-356
-
-
Pan, G.1
Bauer, J.H.2
Haridas, V.3
-
157
-
-
85047700229
-
Tumor necrosis factor-alpha induces the expression of dr6, a member of the tnf receptor family, through activation of nf-kappa b
-
Kasof GM, Lu JJ, Liu D, et al. Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappa B. Oncogene 2001;20:7965-75.
-
(2001)
Oncogene
, vol.20
, pp. 7965-7975
-
-
Kasof, G.M.1
Lu, J.J.2
Liu, D.3
-
158
-
-
38049119903
-
Overlapping cleavage motif selectivity of caspases: Implications for analysis of apoptotic pathways
-
McStay GP, Salvesen GS, Green DR. Overlapping cleavage motif selectivity of caspases: Implications for analysis of apoptotic pathways. Cell Death Differ 2008;15:322-31.
-
(2008)
Cell Death Differ
, vol.15
, pp. 322-331
-
-
McStay, G.P.1
Salvesen, G.S.2
Green, D.R.3
|