Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO- 1/Fas) receptor/ligand system and involves activation of wild-type p53

Journal of Clinical Investigation

Volumn 99, Issue 3, 1997, Pages 403-413

  Müller, Martina ^a   Strand, Susanne ^a   Hug, Hubert ^b   Heinemann, Eva Maria ^a   Walczak, Henning ^c   Hofmann, Walter J ^d   Stremmel, Wolfgang ^a   Krammer, Peter H ^c   Galle, Peter R ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b Center for Molecular Biology   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d Institute of Pathology   (Germany)

Author keywords

Apoptosis; Cancer therapy; CD95; Drug sensitivity; p53

Indexed keywords

BLEOMYCIN; CISPLATIN; COMPLEMENTARY DNA; DOXORUBICIN; FAS ANTIGEN; IMMUNOGLOBULIN F(AB')2 FRAGMENT; METHOTREXATE; PROTEIN P53;

ANTIGEN EXPRESSION; ARTICLE; CELL DEATH; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SENSITIVITY; GENE ACTIVATION; GENE MUTATION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TUMOR SUPPRESSOR GENE;

EID: 0040419494     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119174     Document Type: Article

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