Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody

Journal of Clinical Investigation

Volumn 105, Issue 3, 2000, Pages 329-339

  Feng, Guoping ^a   Kaplowitz, Neil ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CASPASE 3; CASPASE 8; COLCHICINE; DACTINOMYCIN; FAS ANTIGEN; MESSENGER RNA; NOCODAZOLE; PACLITAXEL; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; VINBLASTINE;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; HISTOPATHOLOGY; LETHALITY; LIVER CELL; LIVER PROTECTION; LIVER SINUSOID; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SURVIVAL;

EID: 0033953939     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI7398     Document Type: Article

References (43)

1. Vaux, D.L., and Strasser, A 1996. The molecular biology of apoptosis. Proc. Natl. Acad. Sci. USA. 93:2239-2244.
2. Thompson, C.B. 1995. Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1452.
3. Jacobson, M.D., Weil, M., and Raff, M.C., 1997. Programmed cell death in annual development. Cell. 88:347-354.
4. Nagata, S., and Suda, T. 1995. Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16:39-43.
5. Kerr, J.F.R., Wyllie, A.H., and Currie, A.R. 1972. Apoptosis: a basic biological phenomenon with wide-range implications in tissue kinetics. Br. J. Cancer. 26:239-257.
6. Thornberry, N.A., and Lazebnik, Y. 1998. Caspases: enemies within. Science. 281:1312-1316.
7. Green, D.R. 1998. Apoptotic pathways: the roads to ruin. Cell. 94:695-698.
8. Itoh, N., et al. 1991. The polypeptide encoded by the DNA for human cell surface antigen Fas can mediate apoptosis. Cell. 66:233-243.
9. Nagata, S., Goldstein, P. 1995. The Fas death factor. Science. 267:1449-1456.
10. Nagata, S. 1997. Apoptosis by death factor. Cell. 88:355-365.
11. Ashkenzi, A., and Dixit, V.M. 1998. Death receptors: signaling and modulation. Science. 281:1305-1308.
12. Suda, T., Takahashi, T., Golstein, P., and Nagata, S. 1993. Molecular cloning and expression of the Fas ligand: a novel member of the tumor necrosis factor family. Cell. 75:1169-1178.
13. Griffith, T.S., Brunner, T., Fletcher, S.M., Green, D.R., and Ferguson, T.A. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science. 270:1189-1192.
14. Itoh, N., Suda, T., and Nagata, S. 1993. Lethal effect of the anti-Fas antibody in mice. Nature. 364: 806-809.
15. Galle, P.R. 1997. Apopotosis in liver disease. J. Hepatol. 27:405-412.
16. Faubion, W.A., and Gores, G.J. 1999. Death receptors in liver biology and pathobiology. Hepatology. 29:1-4.
17. Mochizuki, K., et al. 1996. Fas antigen expression in liver tissues of patients with chronic hepatitis B. J. Hepatol. 24:1-7.
18. Hiramatsu, N., et al. 1994, Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology. 19:1354-1359.
19. Galle, P.R, et al. 1995. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J. Exp. Med. 182:1223-1230.
20. Kondo, T., Suda, T., Fukuyama, H., Adachi, M., and Nagata, S. 1997. Essential roles of the Fas ligand in the development of hepatitis. Nat. Med. 3:409-413.
21. Strand, S., et al. 1998. Hepatic failure and liver cell damage in acute Wilson's, disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat. Med. 4:588-593.
22. Adachi, M., et al. 1995. Targeted mutation in the Fas gene causes hyperplasia in the peripheral lymphoid organs and liver. Nat. Genet. 11:294-300.
23. Shiraki, K., Tsuji, N., Shioda, T., Isselbacher, K., and Takahashi, H. 1997. Expression of Fas ligand in liver metastasis of human colonic adenocarcinomas. Proc. Natl. Acad. Sci. USA. 94:6420-6425.
24. Joshi, H.C. 1998. Microtubule dynamics in living cells. Curr. Open. Cell Biol. 10:35-44.
25. Muriel, P., Quintanar, M.E., and Perezalvarez, V. 1993. Effect of colchicine on acetaminophen-induced liver damage. Liver. 13:217-221.
26. Favari, L., Perezalvarez, V. 1997. Comparative effects of colchicine and silymarin on CCL4 chronic liver damage in rats. Arch. Med. Res. 28:11-17.
27. Tregs, G., Freudenberg, M A., Galanos, C., and Wendel, A. 1992. Colchicine prevents tumor necrosis factor-induced toxicity in vivo. Infect. Immun. 60:1941-1945.
28. Kershenobich, D., et al. 1988. Colchicine in the treatment of cirrhosis of the liver. N. Engl. J. Med. 318:1709-1713.
29. Deleve, L.D. 1994. Dacarbazine toxicity in murine liver cells: a model of hepatic endothethial injury and glutathione defense. J. Pharmacol. Exp. Ther. 268:1261-1270.
30. Reinhart, P.H., Taylor, W.M., and Bygrave, F.L. 1982. A procedure for the rapid preparation of mitochondria from rat liver. Biochem. J. 204:731-735.
31. Scharschmidt, B.F., Keeffe, E.B., Blankenship, M.M., and Ockner, R.K. 1979. Studies of relationships among bile flow, liver plasma membrane Na/K ATPase, and membrane microviscosity in the rat. J. Clin. Invest. 64:1590-1598.
32. Hatefi, Y., and Stigall, D.L. 1978. Preparation and properties of succinate: ubiquinone xoreductase (complex II). Methods Enzymol. 53:21-27.
33. Fernandez-Checa, J.C., Takikawa, H., Horie, T., Ookhtens, M., and Kaplowitz, N. 1992. Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats. J. Biol. Chem. 267:1667-1673.
34. Müller, M., et al. 1997. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J. Clin. Invest. 99:403-413.
35. Sorger, P.K., Dobles, M., Tournebize, R., and Hyman, A.A. 1997. Coupling cell division and cell death to microtubule dynamics. Curr. Opin. Cell Biol. 9:807-814.
36. Hofmann, K., and Dixit, V.M. 1998. Ceramide in apoptosis: does it really matter? Trends Biochem. Sci. 23:374-377.
37. Pastorino, J.G., et al. 1996. The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition J. Biol. Chem. 271:29792-29798.
38. Garcia-Ruiz, C., Colell, A., Mari, M., Morales, A., and Fernandez-Checa, J.C. 1997. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J. Biol. Chem. 272:11369-11377.
39. Cock, J.G., Tepper, A.D., de Vries, E., van Blitterswijk, W.J., and Borst, J. 1998. CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase. J. Biol. Chem. 273:7560-7565.
40. Wanner, G.A., Mica, L., Wanner-Schmid, E., Kolb, S.A., Hentze, H., et al. 1999. Inhibition of caspase activity prevents CD95-mediated hepatic microvascular perfusion failure and restores Kuffer cell clearance capacity. FASEB J. 13:1239-1248.
41. Ni, R., et al. 1994. Fas-mediated apoptosis in primary cultured mouse hepatocytes. Exp. Cell Res. 215:332-337.
42. Ding, A.H., Porteu, F., Sanchez, E., and Nathan, C.F. 1990. Downregulation of tumor necrosis factor receptors on macrophages and endothelial cells by microtubule depolymerizing agents. J. Exp. Med. 171:715-727.
43. McDermott, M.F., et al. 1999. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR 1, define a family of dominantly inherited autoinflammatory syndromes. Cell. 97:133-144.